Author Topic: Sovaldi, Ribavirin, and Daklinza for 24 wks, links for them and clinical trials (Read 42749 times)

chuck3a · « **on:** September 16, 2015, 10:36:59 am »

Good morning, All
I am starting this new thread for this combination of treatment, I start my journey today. I had the Pegasys/Ribavirin combination which came back after a month of finishing that combo. That was rough. so I figured if I could handle that combo, this combo should be a lot easier to deal with. Kinda know already what my side effects will be. So to all that follow this one, I wish your 24 wks fly by. and come out healthier on the other end. Thanks for all who make this site a great place to help each other out. Chuck

KimInTheForest · « **Reply #1 on:** September 16, 2015, 11:43:33 am »

Congrats on starting your journey, Chuck! And good luck to you.

kim

chuck3a · « **Reply #2 on:** September 16, 2015, 10:13:02 pm »

I posted this on another thread for molly, so I thought I would copy and paste it here also seeing how it is about the daklinza pills possible side effects.

this is what is on the info sheet they gave me
This information is for MALE patients only. it does NOT include important information for FEMALE patients

For daclatasvir aka daklinza.
rash, hives, itching, red, swollen blistered, or peeling skin with or without fever. wheezing, tightness in the chest or throat, trouble breathing or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue or throat. other minor s/e are headache, feeling tired or weak, upset stomach.

if taken with amiodarone, sofosbuvir and certain other hep c drugs, sometimes it has been deadly, slow heartbeat has happened up to 2 weeks after starting hep c treatment, let your doctor know if signs of slow heartbeat like chest pain, confusion, dizziness, passing out or near-passing out, memory problems, shortness of breath, tiredness or weakness

chuck3a · « **Reply #3 on:** September 16, 2015, 10:22:49 pm »

Quote from: KimInTheForest on September 16, 2015, 11:43:33 am

Congrats on starting your journey, Chuck! And good luck to you.

kim

Thanks Kim, for the encouragement, and may your October labs have you looking like this

badbradley · « **Reply #4 on:** September 17, 2015, 10:48:25 am »

Quote from: chuck3a on September 16, 2015, 10:13:02 pm

I posted this on another thread for molly, so I thought I would copy and paste it here also seeing how it is about the daklinza pills possible side effects.

this is what is on the info sheet they gave me
This information is for MALE patients only. it does NOT include important information for FEMALE patients

For daclatasvir aka daklinza.
rash, hives, itching, red, swollen blistered, or peeling skin with or without fever. wheezing, tightness in the chest or throat, trouble breathing or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue or throat. other minor s/e are headache, feeling tired or weak, upset stomach.

if taken with amiodarone, sofosbuvir and certain other hep c drugs, sometimes it has been deadly, slow heartbeat has happened up to 2 weeks after starting hep c treatment, let your doctor know if signs of slow heartbeat like chest pain, confusion, dizziness, passing out or near-passing out, memory problems, shortness of breath, tiredness or weakness

Her is the prescribing information

http://www.daklinzahcp.bmscustomerconnect.com/treating/

chuck3a · « **Reply #5 on:** September 17, 2015, 11:34:58 am »

Thanks Brad,
I really appreciate the link that you did, I am still a newbie on linking in this forum. and to Molly, sorry about scaring you. from what my care team said, they went to a informational meeting about this pill the day before I started my tx and most of the people just experienced the minor s/e.
Chuck

chuck3a · « **Reply #6 on:** September 17, 2015, 02:01:41 pm »

I am posting some links for daklinza and sovaldi and clinical trials to help others out.

for daklinza:
https://www.medicines.org.uk/emc/medicine/29129
http://packageinserts.bms.com/pi/pi_daklinza.pdf
http://news.bms.com/press-release/fda-approves-daklinza-daclatasvir-treatment-patients-chronic-hepatitis-c-genotype-3
http://www.healio.com/hepatology/hepatitis-c/news/online/%7B8487a256-3dd8-48a0-9fa4-8e2c6feb886b%7D/health-canada-approves-daklinza-for-hcv
http://www.biocentury.com/products/daklinza

for sovaldi
http://hcp.sovaldi.com/
http://hcvadvocate.blogspot.com/search/label/package%20insert
http://hcvadvocate.org/hepatitis/factsheets_pdf/Sovaldi_GT2-3.pdf
http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/204671s000lbl.pdf
http://www.rxlist.com/sovaldi-side-effects-drug-center.htm#

for clinical trials
http://hcvadvocate.blogspot.com/
http://hcvadvocate.org/treatment/drug-pipeline/#FDA
http://hcvadvocate.org/treatment/clinical-trials/

MaryC · « **Reply #7 on:** September 18, 2015, 06:34:52 pm »

Chuck,
Great job getting into a clinical trial. I wish you the best on your exciting journey!

I started Daklinza and Sovaldi on 9/17/15 for 12 weeks. I am also GT 3a. Very happy to start a non-interferon treatment regimen. Perhaps we can exchange stories of our experience, and health tips along this journey.

BTW...love your profile pic.

MaryC

chuck3a · « **Reply #8 on:** September 23, 2015, 02:11:06 am »

Mary,
not sure if I am in a clinical trial, but I am the first in my doc's office to try out this combo. I am also very happy to be on a non-interferon treatment this time, that was rough. 1 week down and 23 to go. and I would love to exchange our experiences on the road to recovery. tomorrow I go in for my first labs. should have the results by Monday at the latest.
on the pic, I wanted to put in the pic of our cocker spaniel mugging the camera, but I couldn't get it to accept it so I went with one of the pics you could use as an avatar on here. well time for me to see if I can get some sleep.
Chuck

Philadelphia · « **Reply #9 on:** September 23, 2015, 06:05:04 am »

Good luck with your bloods - hope you get a nice surprise.

KimInTheForest · « **Reply #10 on:** September 23, 2015, 12:17:13 pm »

Quote from: MaryC on September 18, 2015, 06:34:52 pm

I started Daklinza and Sovaldi on 9/17/15 for 12 weeks. I am also GT 3a. Very happy to start a non-interferon treatment regimen. Perhaps we can exchange stories of our experience, and health tips along this journey.
MaryC

Congrats MaryC on starting treatment! I was Geno 3a too. I think I am cured now. waiting til Oct for my SVR12 lab. In July, I finished 12 weeks of Harvoni+ribavirin. It would have been nice to avoid the riba! I became very anemic. Daklinza wasn't out yet. I will be very interested to hear how you and Chuck and any other Team Daklinza people are doing. Hope it all goes super for both of you.

kim

MaryC · « **Reply #11 on:** September 23, 2015, 06:55:28 pm »

Quote from: KimInTheForest on September 23, 2015, 12:17:13 pm

Congrats MaryC on starting treatment! I was Geno 3a too. I think I am cured now. waiting til Oct for my SVR12 lab. In July, I finished 12 weeks of Harvoni+ribavirin. It would have been nice to avoid the riba! I became very anemic. Daklinza wasn't out yet. I will be very interested to hear how you and Chuck and any other Team Daklinza people are doing. Hope it all goes super for both of you.

kim

Thanks Kim. Very excited to see your results in Oct. Dealing with the anemia from the riba must have been pretty tough. Hopefully this has improved post treatment.

Quote from: chuck3a on September 23, 2015, 02:11:06 am

Mary,
not sure if I am in a clinical trial, but I am the first in my doc's office to try out this combo. I am also very happy to be on a non-interferon treatment this time, that was rough. 1 week down and 23 to go. and I would love to exchange our experiences on the road to recovery. tomorrow I go in for my first labs. should have the results by Monday at the latest.
on the pic, I wanted to put in the pic of our cocker spaniel mugging the camera, but I couldn't get it to accept it so I went with one of the pics you could use as an avatar on here. well time for me to see if I can get some sleep.
Chuck

Chuck...Sorry, I misread your initial post. Good luck tomorrow. I don't go for labs until Oct. 14th. I, too, was happy to be approved for non interferon treatment (my initial denial was overturned on appeal). The Specialty Pharmacy pharmacist said I was the first person she has seen who has been successful in getting the denial for Daklinza and Solvaldi overturned. I feel very fortunate. I am ready to be cured!! I was diagnosed in April of this year. I've given up losing sleep trying to figure how, when (and why) I was infected. I am now focused on recovery and getting strong and healthy!

MaryC

Debula · « **Reply #12 on:** October 01, 2015, 01:56:11 pm »

Congratulations to both of you for starting your new journey with Daklinza
I would also be interested in hearing all about your life with this new drug as my husband is GT3 and doctor told him to come back in November to try to get on this medication. (His initial visit was before FDA approval)
I see that my insurance still does not list it as covered so not sure if we wille ven be able to get it for him.
I just finished my 24 weeks of Harvoni today and I am now part of the waiting Team! I am curious to see what live after Harvoni will be like

Kim I am sure you will be SVR12 at the end of October
Sending good vibes and best wishes to all of you

Deb

chuck3a · « **Reply #13 on:** October 16, 2015, 04:46:35 am »

Hi all, just did my 4 week labs on the 14th of Oct. got some of the results in, look at my signature for the alt/ast results. should hear about my vl in next day or so. hoping for that ud, but if not got another 20 more weeks to achieve it. lol

. saw the post about joint and muscle pain, I am experiencing that also. started around week 2.5 in my both of my legs and in groin area on left side, plus slightly in other parts of my body, the one I thought would really act up is my back, but it hasn't changed much from normal (for me) pain. been using a TENS unit (electrical stimulation) and heating pad together on my legs and it helps a lot, but when it doesn't I use the Vicodin and flexeril (muscle relaxer) that's for my back to get some sleep. I will post my vl in the next day or so. get to see my doc on Monday to go over every thing on my labs.

chuck3a · « **Reply #14 on:** October 18, 2015, 04:53:12 am »

just got my labs back from Oct. 14 2015,
7/24/15 10/14/15
Hepatitis C Qnt Interp detected not detected

Hepatitis C Quant 1656491 not detected
<=15 IU/mL

Hepatitis C Quant Log 6.2 not detected
<=1.2 LOG 10

that is what I wanted and waited to see. woo-hoo

Philadelphia · « **Reply #15 on:** October 18, 2015, 05:22:06 am »

those are great numbers!

Cal · « **Reply #16 on:** October 18, 2015, 06:07:03 am »

Chuck,
Good on you! Cal

lporterrn · « **Reply #17 on:** October 21, 2015, 11:05:33 am »

great lab results Chuck!

chuck3a · « **Reply #18 on:** October 23, 2015, 02:51:54 am »

Thanks Philadelphia, Cal, and Iportern, for the support. also Maryc too,
I do have to go in for a EPO injection due to my HGB has dropped to 9.9. and also to take only 4 Ribavirin pills a day instead of 5. to see if that helps my HGB to go back up. but again thanks for the support from all on this forum.

Cal · « **Reply #19 on:** October 24, 2015, 12:33:30 am »

Hi Chuck,
Its not unusual to take down a riba or two. I was taken down two for 7 weeks and put up again 2 weeks ago to 4. I was orginally 5. What is an EPO injection? Cal

chuck3a · « **Reply #20 on:** October 24, 2015, 01:06:44 am »

Hi Cal,
I wasn't sure what a epo injection was either, so this is from the mayo clinic website. I don't have the kidney problem, I believe it is from the riba pills doing their job.

Epoetin injection is a man-made version of human erythropoietin (EPO). EPO is produced naturally in the body, mostly by the kidneys. It stimulates the bone marrow to produce red blood cells. If the body does not produce enough EPO, severe anemia can occur. This often occurs in patients whose kidneys are not working properly. Epoetin is used to treat severe anemia in patients with kidney disease.

Epoetin may also be used to prevent or treat anemia that is caused by surgery or medicines that are used for other conditions, such as AIDS or cancer.

Cal · « **Reply #21 on:** October 25, 2015, 04:49:49 am »

Hi Chuck,
Thanks for that information. You must be severely anaemic then, we have different measurements her in Australia. How are you feeling? Cal

chuck3a · « **Reply #22 on:** November 13, 2015, 04:36:32 am »

had to go back to get more labs for the epo injections, finally got approved 2 days ago. have to start on this Saturday for 9 injections spaced out every 2 weeks. Thinking about changing my name from chuck3a to pincushion Charlie.

lol The riba from what my doc is telling me is the cause for my anemia. My HGB was 9.9 on 10/14 and on 11/11 it is 9.8 ref range is 13.6-18.0 gm/dL. I am feeling pretty tired and rundown. but with these epo injections hope to feel better soon.
Also went in for my labs on 11/11/15 and my ast/alt results are on my signature now. will get my vl on next set of labs on Dec. 9th.
So about half way thru tx. now and some of the s/e are going away. the fogginess, and most of the joint and muscle aches.

Philadelphia · « **Reply #23 on:** November 13, 2015, 04:52:37 am »

My riba dose was reduced too, so I managed to keep my hb above 100 (just). Your numbers
(with the exception of hb) are looking awesome!

Dj5263 · « **Reply #24 on:** November 14, 2015, 11:19:15 pm »

First of all I would like to thank you all for sharing this has helped me greatly I am currently taking dazlinza and sovaldi in six days will be 4 weeks. Then I will have blood work done.

I went to my regular dotor for a physical and blood work. This is when I found out I had hep c. I was in disbelief and actually ignored it hoping I could be one of lucky ones and it would go away. Yea that was silly on my part.

Went to a specialist started treatment when I get the results I will repost.

Cal · « **Reply #25 on:** November 15, 2015, 07:04:36 pm »

Hi CHuck,
You are doing it hard. I am severely run down from the ribas, I stopped them last Thursday, now to wait for them to leave my body and get those HB numbers up again. It knocks the wind out of your sails for sure! Cal

chuck3a · « **Reply #26 on:** November 17, 2015, 01:46:58 am »

Hi Cal, Philadelphia, and welcome to the forums, Dj5263, some good people on here, to help you thru it all.
so went in for the epo injections Saturday, they had to test my HGB before giving me the shot. well my HGB was at 8.9 then, so it had dropped .9 in 4 days. still on just 4 riba's a day. still feel pretty tired and rundown, probably take a couple of more shots before it starts to go back up again. and my hematocrit has also dropped too. over last 4 years it's been around 34.9 - 39.5% but since I started this tx it has been going down. 36.8 to 31.3% since 7-24-15 to 11-11-15. but a big drop from 11-11-15 to 11-14-15 it dropped to 27.9%, not sure what this means, so time to read up on it. the ref range is 39.8 to 52% so it's been low since first tx.

chuck3a · « **Reply #27 on:** November 19, 2015, 04:38:41 am »

Quote from: chuck3a on September 17, 2015, 02:01:41 pm

I am posting some links for daklinza and sovaldi
for daklinza:
https://www.medicines.org.uk/emc/medicine/29129
http://packageinserts.bms.com/pi/pi_daklinza.pdf
http://news.bms.com/press-release/fda-approves-daklinza-daclatasvir-treatment-patients-chronic-hepatitis-c-genotype-3
http://www.healio.com/hepatology/hepatitis-c/news/online/%7B8487a256-3dd8-48a0-9fa4-8e2c6feb886b%7D/health-canada-approves-daklinza-for-hcv
http://www.biocentury.com/products/daklinza

for sovaldi
http://hcp.sovaldi.com/
http://hcvadvocate.blogspot.com/search/label/package%20insert
http://hcvadvocate.org/hepatitis/factsheets_pdf/Sovaldi_GT2-3.pdf
http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/204671s000lbl.pdf
http://www.rxlist.com/sovaldi-side-effects-drug-center.htm#

Cal · « **Reply #28 on:** November 19, 2015, 04:52:09 pm »

Hi chuck,
Us it ok if I cut and paste that for a friend on the same combo and same geno as you? Cal

chuck3a · « **Reply #29 on:** November 20, 2015, 12:04:52 am »

Hi Cal
sure, I was trying to get rid of the clinical trial stuff, seeing how it is old now. but share away. btw congrats again. So glad that your labs came back with the great news, even if they were a day late. chuck

Cal · « **Reply #30 on:** November 20, 2015, 01:57:31 am »

Thanks Chuck,
He will be very happy to get more info. He lives on an island so is cut off from other heppers. And thanks again for your kind congratulations. Cal

chuck3a · « **Reply #31 on:** November 20, 2015, 02:41:54 am »

http://www.hepmag.com/articles/ALLY_3_2501_28049.shtml?utm_source=homepage&utm_medium=tji1&utm_campaign=conference

Hi Cal, was just reading this on the home page, it concerns the 3 meds that I am taking, you should pass it on to your friend. just listed on the 16th of Nov. I was also reading on Billt's page about the lichen planus, I have the same thing going on too, wonder if anyone who has finished tx has this disappeared, my hep doc always put it down to my high ferritin level, for me it has always been high, in the 700's, even after a phlebotomy for 8 weeks during first treatment in 2009 it dropped to 400's but quickly went back to 700's ref range is 22-322, then he said it may be because I am American indian that is why my ferritin level is high and that caused the rash/scaly skin. the iron in my blood pooling in my legs. next time I see him in Dec. I will bring it up to him.

Cal · « **Reply #32 on:** November 20, 2015, 05:46:54 pm »

Hi chuck,
I won't give him that link, as he's on 12 weeks and it obviously is mire effective for longer, so I don't want to give him anything to make him worry. This is his 3rd tx.

Thanks though. There's some good stuff coming out of the San Francisco conference that finished Wednesday. It can be googled.

I have lichen planus, my skin is really effected. I also have vitiligo and have list 50% if my pigment all HCV related. I'll try to find a good publication for you on HCV co morbidities. I gave, small vein and peripheral neuropathy, cardiomyopathy, slight brain damage and a hist if auto immune issues and diseases. I get my whole thyroid removed after this tx. At a Hep Q and A I recently spoke at, I asked the Doctors in the audience to start looking at HCV as an all body illness not just the liver. You can have fibrosis 0 and be disabled or dying from HCV.

Cal

Cal · « **Reply #33 on:** November 20, 2015, 05:49:34 pm »

Here's the link Chuck to HCV co morbidities. Cal

http://www.hindawi.com/journals/jir/2012/236148/

Hope it still works

chuck3a · « **Reply #34 on:** November 21, 2015, 01:55:09 am »

Hi Cal,
I could see why you would not like your friend to see that link, longer that you are on tx the better chance, especially with being a 3x relapser.
and thanks for the link, it still works. Going to have to share that with my hep doc, some of it was over my head, but got the basic glist of it. and it explains a lot of the changes I have been going thru the last 5-6 years. going to break out my medical dictionary. so I can understand the whole thing. Thanks Chuck

Cal · « **Reply #35 on:** November 21, 2015, 02:12:21 am »

Hi chuck,
It is a tad wordy isn't it. HE he! I took it to my GP and she scanned it in too my file. The Doctors respond to it because it's in the lingo. I think it's a worthwhile publication, it certainly validated a lot of my symptoms.

Yes I feR my friend should be on the combo longer but he is unable, you get what you're given. I think hell clear though. I just don't want him fretting. Cal

Dj5263 · « **Reply #36 on:** November 27, 2015, 03:22:35 pm »

Got the results after 5 weeks.....hep c undetected
Liver functions....normal
CBC...normal
Still have 7weeks of meds but my doctor told me to see him in six months
Holiday week could not get a hold of him have to wait till monday

KimInTheForest · « **Reply #37 on:** November 27, 2015, 03:58:37 pm »

Quote from: Dj5263 on November 27, 2015, 03:22:35 pm

Got the results after 5 weeks.....hep c undetected
Liver functions....normal
CBC...normal

Way to go DJ!

kim

Dj5263 · « **Reply #38 on:** November 27, 2015, 04:55:35 pm »

Thank you Kim I was going to call the doctor I was getting pains in my chest and experienced almost passing out. But being the ex. Party I was this was a normal sensention to Me...lol

Cal · « **Reply #39 on:** November 27, 2015, 09:32:16 pm »

Hi DJ,
What drugs are you taking? Are you taking ribas? Maybe you can fill in your profile signature then we can see where you're at with your treatment. Different drugs have different side effects. You should see a Doctor more regularly than what he's saying. You need to have ongoing blood tests. Cal

chuck3a · « **Reply #40 on:** November 28, 2015, 01:17:01 am »

Hi DJ
great news on the results.
did your doctor schedule you for blood work at all for the next 7 wks. of meds? and not to see him for the next 6 months, that's a pretty long time. I am on wk. 12 of 24. and I get blood work every month now. and have appts. with my doc every other month. unless he sees something in my tests, then he wants me to come in asap. then at eot on Feb 15 or so. I go in at 12 wks. and 24 wks. after that to check and make sure I'm staying hep free

chuck3a · « **Reply #41 on:** December 17, 2015, 10:46:57 pm »

Good Day All,
just got in my latest lab results, vl - und, and in my signature my ast/asl both went down a notch. just picked up my 4th 28 day supply of pills, I just realized I have until march to hit EOT. went in for another EOP injection Saturday, my hgb dropped back down to 9 from 9.8 2 weeks ago. and just finished moving. was getting about 2 hrs. of sleep a day between work and packing and moving for the last 7 days. managed to get 5 hrs. last night, but still run down. well going to go for now, kinda feeling bummed out.

Cal · « **Reply #42 on:** December 18, 2015, 07:34:27 pm »

Hi Chuck,
Congrats on the UND, love your work

Of course you feel bummed out. OMG your HB is low. What did the Doctor say about it? Sometimes they reduce the ribas to help. I had a reduced riba amount from the second week until I was manageable then went back up. I still made UND at EOT. Ribas are the pits. The gift that keeps on giving I call it. Be gentle with yourself if you can. Moving?

OMG how high up the stress scale is that? What bad timing, nevermind you did it. Remember that it's all the ribas and you will get your mind and body back when those pesky things are gone. Also do you have anything to help you sleep? I found the upside of being on anti histamines for itch was that they made me sleep. Cal

chuck3a · « **Reply #43 on:** January 29, 2016, 03:38:10 am »

just got my latest labs in ast and alt both down and vl is still undetected. but just changed insurances due to new job and insurance company is fighting the last 8 weeks of pills. got 7 days of pills left, that will make it 16 wks of treatment. suppose to have 24 wks due to prior relapse from pegsys and ribapak. just hope that if I don't get the last 8 wks of pills that I don't relapse again. and hope the 16 weeks were good enough for the cure.

KimInTheForest · « **Reply #44 on:** January 29, 2016, 03:49:09 am »

Quote from: chuck3a on January 29, 2016, 03:38:10 am

just got my latest labs in ast and alt both down and vl is still undetected. but just changed insurances due to new job and insurance company is fighting the last 8 weeks of pills. got 7 days of pills left, that will make it 16 wks of treatment. suppose to have 24 wks due to prior relapse from pegsys and ribapak. just hope that if I don't get the last 8 wks of pills that I don't relapse again. and hope the 16 weeks were good enough for the cure.

These insurance companies are just too much - going against doctors' instructions about what the patient needs. I hope you can lobby them to get the full 24 weeks, although of course the time is tight. Congrats on your latest labs! That's all very re-assuring.

good luck!
kim

AussieRosa · « **Reply #45 on:** January 29, 2016, 05:13:49 am »

Chuck, so sorry to hear the insurance company is trying to sabotage your treatment. I hope you manage to get the rest of the meds approved. Good luck!

lporterrn · « **Reply #46 on:** January 29, 2016, 12:33:11 pm »

Chuck - If your doctor's office isn't set up to be very proactive with your insurance company, contact the drug company or a patient assistance program. In a pinch they will send or help you get medication https://www.hepmag.com/basics/hepatitis-c-basics/paying-hepatitis-c-treatment

Rocket Girl · « **Reply #47 on:** February 01, 2016, 12:52:43 pm »

Just received word KAISER Permanente will check my Viral count at 4 & 12 wks. My big mouth and Southern friend paid off. I feel for all of you fighting insurance. I didn't have it in me, so I purchased medicine abroad. Anyone going my route, make sure you have a plan B for blood tests.

Rocket Girl · « **Reply #48 on:** February 01, 2016, 02:05:02 pm »

I sure have a hard time with this site and keeping up with everyone. I wish when I logged in, the posts would reflect the most recent replies and then work there way down, but it appears to be the opposite. I don't have much to offer as I have never done therapy up until now- Harvoni. and up until this point I used natural therapies waiting for this wonderful medicine. but you are all in my prayers. that you will get treatment, minimal side effects and undetectable virus . . . Completely healed. try to drink a lot of liquids, exercise . . . remember it's the consistency that counts and try to stay busy, good thoughts❤️❤️❤️

chuck3a · « **Reply #49 on:** February 06, 2016, 02:58:29 am »

Good evening All, I was on week 20 of 24 weeks of tx. It has been 7 days since that I took my last pill of wk 20. I just finally got approved thru my new insurance, my GI doctor and staff fought for me pretty hard, it was the new insurance company that resisted the coverage. what I would like to find out is since it will probably be 11 days since my last pills before I can get the last 28 day script sent to me, will there be a problem due to the time frame of missed dosages. I am a prior re-lapser (see signature), Thanks,
Chuck

KimInTheForest · « **Reply #50 on:** February 13, 2016, 03:50:38 pm »

Quote from: chuck3a on February 06, 2016, 02:58:29 am

Good evening All, I was on week 20 of 24 weeks of tx. It has been 7 days since that I took my last pill of wk 20. I just finally got approved thru my new insurance, my GI doctor and staff fought for me pretty hard, it was the new insurance company that resisted the coverage. what I would like to find out is since it will probably be 11 days since my last pills before I can get the last 28 day script sent to me, will there be a problem due to the time frame of missed dosages. I am a prior re-lapser (see signature), Thanks,
Chuck

Good luck Chuck! Damn those insurance companies! What did your doc say about the stoppage of treatment for 11 days due to insurance company resisting further coverage for you? I think your chances of cure are still really good! But I'm no doctor.

Keep us posted,
kim

one more time · « **Reply #51 on:** February 13, 2016, 07:17:17 pm »

Chuck
I too start today, I couldn't tolerate Peg/Ribavarin stopped at 7 weeks, then did a 24 week Solvaldi/Riba combo, only to have it interrupted twice by the insurance mongrels. The insurance has only approved me for 12 weeks, the doctor is appealing. Geno type 3, V/L 1.7 million; AST 75-ALT 110, F -3. I've waited 2 years between treatments. Hope the 3rd time is the charm!

KimInTheForest · « **Reply #52 on:** February 13, 2016, 10:10:02 pm »

Quote from: one more time on February 13, 2016, 07:17:17 pm

Chuck
I too start today, I couldn't tolerate Peg/Ribavarin stopped at 7 weeks, then did a 24 week Solvaldi/Riba combo, only to have it interrupted twice by the insurance mongrels. The insurance has only approved me for 12 weeks, the doctor is appealing. Geno type 3, V/L 1.7 million; AST 75-ALT 110, F -3. I've waited 2 years between treatments. Hope the 3rd time is the charm!

Good luck one-more-time! And welcome to the forums.

kim

one more time · « **Reply #53 on:** February 18, 2016, 04:35:54 pm »

Thanks Kim,
Been a week and the TX seems stronger this time or am getting flu, who knows lol. I was taking supplements but stopped prior to TX. Has anyone continued supplements on the TX? If so what were they?
I go see another doctor tomorrow trying to get my treatment extended to 24 weeks, (transplant hospital, friend of my GI doc, he thinks if they way in on the appeal, the insurance will change their mind) Ridiculous way to do things

chuck3a · « **Reply #54 on:** February 24, 2016, 02:36:45 am »

good evening all, well it looks like i will be moving over to the post tx side. after missing 14 day of no meds. the insurance company and pharmacy got their act together, I decided to tell them never mind, it's been too long of a period of missed doses to start again. what really pisses me off is that on jan 27th my last dose, they had both approved my last 4 wks but due to miscommunication between them, they didn't really tell me that until the 12th of feb. that i was approved. after calling them a couple of times a day starting jan 24th, that I talked to my gi doc. and his staff that it was approved by both of them. that I got a straight answer, that oh yes we do see that it was approved on the 27th of jan that was on feb 12th. the one time I am so glad of riba rage, I just went off on both of them, so if you have blue cross/blue shield of tenn. and cvs pharmacy, be prepared for bs. so now I wait until april 27th to get my 12 wk eot labs to see if I am still und. I did manage to get 20 of the original 24 wks of tx. so hope it stays und. Hopefully you will not see anymore posts from me on this side of the this wonderful forum. I have meet some really supportive people here. Cal, Philly, Kim,lporterrn, molly, plus way too many others to mention. THANKS FOR THE SUPPORT.

Philadelphia · « **Reply #55 on:** February 24, 2016, 03:36:29 am »

I can see why you'd be furious. But you got 20 weeks, your numbers are awesome and I have a good feeling about this. My good feeling has no scientific basis but I feel it nonetheless. Everything's crossed for you.

Also, document everything in case you need to go head to head with the insurance guys again. Bloody negligent I call it.

KimInTheForest · « **Reply #56 on:** February 24, 2016, 01:00:31 pm »

Good luck Chuck! And I'm with Philadelphia - your numbers look great, so there is a very high likelihood that you are rid of Hep C for good. Still no excuse for insurance company and pharmacy interfering with your prescribed course of treatment in this way. Negligent indeed! (or incompetent)

kim

chuck3a · « **Reply #57 on:** April 02, 2016, 01:14:54 am »

3-28-16 test results 8 weeks EOT (my hep doc wanted to test me since I didn't get the last 4 weeks of the 24 wks I was suppose to take it for. so 20 wks and
hep c virus not detected.
all the ones in blue I am either low or high on.
Hemoglobin 10.8 (L) 13.6 - 18.0 gm/dL Final
Hematocrit 33.9 (L) 39.8 - 52.0 % Final
MCV 68.5 (L) 80.0 - 97.0 fL Final
MCH 21.8 (L) 26.0 - 34.0 pg Final
MCHC 31.9 (L) 32.0 - 36.0 gm/dL Final
RDW 16.6 (H) 11.5 - 15.0 % Final
Component Value Ref Range & Units Status
Sodium 138 136 - 145 mmol/L Final
Potassium 4.0 3.6 - 5.0 mmol/L Final
Chloride 104 98 - 107 mmol/L Final
Carbon Dioxide 27 22 - 28 mmol/L Final
BUN 14 6 - 20 mg/dL Final
Creatinine 1.09 0.70 - 1.30 mg/dL Final
Glucose 159 (H) 74 - 100 mg/dL Final
Calcium 9.3 8.6 - 10.3 mg/dL Final
Total Protein 7.1 6.0 - 8.3 gm/dL Final
Albumin 3.8 3.5 - 5.0 gm/dL Final
SGPT/ALT 13 10 - 35 U/L Final
SGOT/AST 18 14 - 50 U/L Final
Alkaline Phosphatase 92 53 - 128 U/L Final
Total Bilirubin 1.3 (H) 0.3 - 1.2 mg/dL Final

MaryC · « **Reply #58 on:** April 02, 2016, 09:00:46 am »

Congrats chuck3a on the good news despite missing the last 4 weeks of tx. Your guardian angel (Neo) has been looking out for you for sure! Will your next labs be at 12 weeks EOT?

Mary

chuck3a · « **Reply #59 on:** April 03, 2016, 01:24:33 am »

thanks for the congrats mary, I haven't seen my gi doc yet, but it should be week 24 eot that I should do my next labs. so around july 27th is when I should get final answer if it is still und.

Philadelphia · « **Reply #60 on:** April 03, 2016, 07:40:21 am »

Looking good so far!

chuck3a · « **Reply #61 on:** February 03, 2017, 08:55:53 am »

1 year 1 month hep c free.

KimInTheForest · « **Reply #62 on:** February 22, 2017, 11:44:24 pm »

Quote from: chuck3a on February 03, 2017, 08:55:53 am

1 year 1 month hep c free.

Way to go Chuck!!! I was 3a also. Have been Hep C free 1.5 years! Time to celebrate.

kim

Philadelphia · « **Reply #63 on:** February 24, 2017, 04:00:47 am »

Congrats on your milestone!

Forums Index

Welcome

Author Topic: Sovaldi, Ribavirin, and Daklinza for 24 wks, links for them and clinical trials (Read 42749 times)