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Author Topic: Toothpaste be aware  (Read 5401 times)

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Offline Steve76

  • Member
  • Posts: 26
Toothpaste be aware
« on: December 01, 2015, 02:03:21 pm »
I on Harvoni just starting my third week.  I want to alert people to the  fact that most natural Toothpastes have Calcium Carbonate as the #1 ingredient.  I have been using this Toms of Maine for 3 weeks looked at the ingredients and Calcium Carbonate is #1. Had no idea about it being in there.

I brush my teeth 1st thing in the morning and then take my Harvoni pill right afterwords.  I don't knowingly swallow any Toothpaste but probably a bit gets swallowed plus any residue.  Kind of freaking out now,  I have changed out the Toothpaste for myself(wife likes the natural crap) and am using Colgate now with flouride. 

Very worried I compromised my treatment.  I worry a lot anyway...

Offline dragonslayer

  • Member
  • Posts: 873
Re: Toothpaste be aware
« Reply #1 on: December 01, 2015, 03:20:54 pm »
Is Calcium Carbonate contraindicated for use with Harvoni in the quantities you might absorb during tooth brushing?
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: Toothpaste be aware
« Reply #2 on: December 01, 2015, 03:37:45 pm »
Steve, Harvoni's manufacturer Gilead has a web site (www.harvoni.com) and 24/7 nurse line. You can ask if the tiny amount you may have ingested is a problem. I'm guessing it isn't.

Welcome to the Hep Forum.

Gnatty
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Re: Toothpaste be aware
« Reply #3 on: December 02, 2015, 03:57:46 am »
Hi Steve and welcome,

The concern is antacids (e.g., aluminum and magnesium hydroxide) like tums which should be taken no closer to harvoni than 4 hours before and at least 4 hours after taking harvoni.

Other antacids contain calcium carbonate but the amount you might ingest with tooth brushing is negligible as compared with chewing a couple of calcium carbonate antacid tabs. So I truly believe you are fine.


Tooth paste is not listed on the prescribing information sheet for harvoni.

https://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/harvoni/harvoni_pi.pdf

But as Gnatty suggested you can call the nurse line for peace of mind.

Good luck on treatment
Lynn
« Last Edit: December 02, 2015, 04:02:15 am by Lynn K »
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

 


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