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Author Topic: Harvoni  (Read 9301 times)

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Offline Rascal

  • Member
  • Posts: 3
Harvoni
« on: July 21, 2015, 02:30:56 pm »
Newbie here.....

I started Harvoni about 6 weeks ago.  After my first 28 days my viral load went from 3.5 million to less than 15.  My Liver Functions tests were normal for the first time since I contracted/diagnosed and or had LFTs on a recurring basis.  I know the goal is not detectable and hopefully the next test will be there.   No side effects that I've noted. 

Genotype 1A.

Thanks, Rascal

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Harvoni
« Reply #1 on: July 21, 2015, 04:12:50 pm »
Congrats Rascal! And welcome to the forums! Sounds like you are on your way to being cured! :)

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Rascal

  • Member
  • Posts: 3
Re: Harvoni
« Reply #2 on: July 22, 2015, 07:53:14 am »
Thank you very much. 

Offline Else

  • Member
  • Posts: 523
  • Appeal, appeal, and appeal again!
Re: Harvoni
« Reply #3 on: July 22, 2015, 12:54:14 pm »
That's fantastic, Rascal.  I think I read somewhere on these forums that the viral test doesn't go below 15 on labs reports. 

Quote
A result of "<15 IU/mL (<1.18 log IU/mL)" indicates that HCV RNA is detected, but the HCV RNA level present cannot be quantified accurately below this lower limit of quantification of this assay.

In other words, I'm pretty sure your considered clinically "virus undetected" right now! Add that to normal liver function tests and I'd start celebrating immediately.  ;D

Best of luck in completing your course of treatment - you've totally got this.  8)

F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline Rascal

  • Member
  • Posts: 3
Re: Harvoni
« Reply #4 on: July 22, 2015, 02:42:59 pm »
Thanks Else.  I'm feeling pretty good about those numbers!  Ron

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: Harvoni
« Reply #5 on: July 22, 2015, 08:54:16 pm »
Hi different labs may report differently this was my 4 week post test result for reference

Component Results

Component   Standard Range   Your Value

HCV RNA RT-PCR, QT   See Notes IU/mL   See Below
HCV Not Detected

HCV QNT TEST INFO   See Notes   See Below

The quantitative range of the assay is 15 IU/mL to 100 million IU/mL
using COBAS(R) TaqMan(R) HCV test, v 2.0. The limit of detection (LOD)
and lower limit of quantification (LLOQ) for this assay is 15 IU/mL.
Results less than the quantitative range of the assay will be reported
as "HCV RNA detected, less than 15 IU/mL".
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

 


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