Hepatitis Forums

Hepatitis C Main Forums => Considering Hepatitis C Treatment => Topic started by: Hippo on August 22, 2015, 12:26:34 pm

Title: interactions with Harvoni
Post by: Hippo on August 22, 2015, 12:26:34 pm

How does beer interact with the success of harvoni.  Facts please not opinions.  Thank you.

Title: Re: interactions with Harvoni
Post by: Mike on August 22, 2015, 03:39:00 pm

Hi Hippo,
Since Harvoni is such a new drug, there is no definitive research either way. Because of this, and, to error on the side of caution, I would recommend abstaining from alcohol during treatment.

I would talk to your doctor about this.

Best wishes, Mike

Title: Re: interactions with Harvoni
Post by: hepboy1 on October 07, 2015, 07:45:48 pm

has anyone taken milk thistle on harvoni?  sorry cant figure out how to make own post  yet

Title: Re: interactions with Harvoni
Post by: Lynn K on October 08, 2015, 07:53:32 pm

hepboy1

http://www.webmd.com/drugs/2/drug-167109/harvoni-oral/details/list-interaction-details/dmid-2412/dmtitle-strong-or-moderate-cyp3a4-inhibitors-simeprevir/intrtype-drug

Harvoni
Interactions
Simeprevir/Strong or Moderate CYP3A4 Inhibitors

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:

Amprenavir, aprepitant, atazanavir, boceprevir, cimetidine, ciprofloxacin, clarithromycin, cobicistat, conivaptan, crizotinib, cyclosporine, darunavir, diltiazem, dronedarone, erythromycin, fosamprenavir, fluconazole, imatinib, indinavir, itraconazole, ketoconazole, lopinavir, mibefradil, milk thistle, nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telaprevir, telithromycin, tipranavir, troleandomycin, verapamil, or voriconazole may speed up how quickly your liver processes simeprevir.
What might happen:

The amount of simeprevir in your blood may increase and cause more side effects than expected.

Title: Re: interactions with Harvoni
Post by: dragonslayer on October 09, 2015, 09:14:57 am

Lynn, I believe that site is referring primarily to Olysio interactions, not specifically Harvoni.  It's misleading because it lists both, but if you check other interaction sites re Harvoni and Milk Thistle, I dont believe youll find a connection.

Title: Re: interactions with Harvoni
Post by: Scoutdoy on October 09, 2015, 10:46:16 am

Hippo,
     This is not factual but take it for what it's worth. Giliad did not have any data on alcohol and Harvoni. As far as I know, there is no direct evidence one way or the other with it interfering with the way Harvoni works to clear the virus. Here is what my doc told me about taking different things while on Harvoni. He said No, it doesn't interfere with the Harvoni directly but when one is trying to rid the body of a virus or disease it is best to have all organs functioning at the highest level they can to rid the virus. The liver being one of the most important organs while doing this. Alcohol makes the liver not function at its highest capability while ridding itself of the alcohol consumed. Whether it's 2 hrs for one drink or a whole day for a 12 pack.


Scout

Title: Re: interactions with Harvoni
Post by: Lynn K on October 09, 2015, 11:29:57 pm

oops Dragon you are correct. I googled Harvoni interactions guess it pays to read the whole article thanks!

Still though I would think we would want to err on the side of caution while treating and just don't take anything we don't have to and never without our doctors agreement.