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Author Topic: The Big Problem With Liver Biopsies  (Read 6570 times)

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Offline Hep Editors

  • Member
  • Posts: 784
    • Hep Mag
The Big Problem With Liver Biopsies
« on: August 20, 2015, 02:00:00 pm »
Heads up hep C-positive people! A new study published in the American Journal of Gastroenterology says relying on liver biopsies alone to diagnose cirrhosis likely misses up to 75% of cases!!

http://www.hepmag.com/articles/cirrhosis_diagnosis_method_2501_27665.shtml

Offline Jorah

  • Member
  • Posts: 113
Re: The Big Problem With Liver Biopsies
« Reply #1 on: August 24, 2015, 10:04:06 pm »
Wow !!
« Last Edit: August 24, 2015, 10:19:07 pm by Jorah »

Offline dragonslayer

  • Member
  • Posts: 873
Re: The Big Problem With Liver Biopsies
« Reply #2 on: August 27, 2015, 05:21:26 pm »
I guess the gold standard isnt so golden anymore!  Thats a real bummer, because heretofore, it was the most accurate and reliable indicator of liver condition.   The noninvasive tests have always been known to be unreliable in the middle ranges at least.  So what are we left with thats better?   Maybe the biopsy can still be used for determination of liver condition if its in the F0-F2 range, but should be teamed with Fibroscan, for instance, which might now be the better option for detecting cirrhosis..?
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

 


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