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Author Topic: FDA Approves Merck's Zepatier for Genotypes 1 and 4  (Read 6848 times)

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Offline gnatcatcher

  • Member
  • Posts: 1,372
FDA Approves Merck's Zepatier for Genotypes 1 and 4
« on: January 29, 2016, 06:28:46 pm »
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline FutureThinker

  • Member
  • Posts: 711
  • Onward and upward!
Re: FDA Approves Merck's Zepatier for Genotypes 1 and 4
« Reply #1 on: January 30, 2016, 05:03:52 pm »
Just saw this news on Zepatier!! Also, for anyone who needs a dose of hope, go to Hepmag's homepage under "Most Viewed" on the right, and read the article, "2016 Hepatitis C drug Approval Outlook" dated 1-15-16.  THIS IS GOING TO BE THE YEAR FOR A LOT OF US!!!!!

***** A new and very important recommendation for treatment with this new drug is pre-treatment testing for NS5A polymorphisms.  I got into an argument with my doctor about the benefit of this before starting any of the available drugs for GT1 and he thought I was crazy........ there is going to be more specific testing done before any of these are prescribed in the very near future, IMHO. Thanks for posting, FT
Treatment naive
Likely contracted mid-70s
Diagnosed 1a, 2011
F1-2
Harvoni X 12 weeks, completed 5/17/16
Pre-treatment: VL 3 mil, AST 64, ALT 84
4 week labs: VL 30, AST 21, ALT 14
8 week labs: VL UD!!!, AST 22, ALT 16
12 week labs: VL UD, AST 23, ALT 14
2 wk EOT: VL UD
12 wk EOT: VL UD, AST 22, ALT 13 =  SVR 12! Yay! 
Last hep appointment: VL UD, AST 19, ALT 12 = SVR 39! I AM DONE!

 


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