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Author Topic: Two year follow up  (Read 9466 times)

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Offline Mike

  • Member
  • Posts: 999
Two year follow up
« on: November 28, 2016, 06:26:00 pm »
I have a two year follow-up with my GI. I've had all the blood work (i.e., fibrosure, CMP et. al.) and I have a fibroscan scheduled for December 1st.

I see the GI on December 15th.

In short, I completed a 12 week course of SOL+INTF+RIB in early 2014, cleared the virus, attaining an SVR 12, 24 and 52.

Prior to treatment, I had grade 2 fibrosis. My AST & ALT levels have ranged from 14-24 since clearing the virus.

I'm hoping that my fibrosis score is below 2, which means my liver is/has rejuvenated. If not, at least I stopped the progression.

I'll post my 2 year results after I meet with the GI.

Best wishes, Mike
Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014

Offline Lynn K

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  • Member
  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: Two year follow up
« Reply #1 on: November 28, 2016, 06:54:57 pm »
 Good luck with your testing Mike hopefully you will see a regression in your fibrosis level
« Last Edit: November 29, 2016, 01:08:22 am by Lynn K »
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline dragonslayer

  • Member
  • Posts: 873
Re: Two year follow up
« Reply #2 on: November 28, 2016, 11:25:04 pm »
Good luck Mike on your 2 yr followup.   Hoping you regressed like crazy; looking forward to your results!
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline jakas

  • Member
  • Posts: 265
Re: Two year follow up
« Reply #3 on: November 30, 2016, 05:46:27 am »
Yep looking forward to the results. I know they are gonna be great
M/57 yrs.
Contracted (Unknown) 10-20-30 yrs back ??
Treatment Naive
Geno 1a&1b
VL  17+ million
ALT 200+, AST 170+
Fibroscan F4 ( 26+ kpa ) on 8th Dec. 2105
Started Tx 11th Dec.2015 ( 12 wks. Gilead Harvoni)
7/1/2016 :Viral Load|<25 UND.
23/1/2016: ALT 34 , AST 35, ALP 143
8 week NO labs done
EOT:03.03.2016 ( 84 pills eaten )
ALT 26, ALP 124, BIL .54
V/L <25 UND E.O.T.
4 weeks E.O.T. V/L UND::: SVR 4
SVR 12 and  SVR 24 on 16/8/16
Fibro 24.5kpa 23/05/16
SVR 63 05/17
Fibro 17.03.2020 kpa 6.3

Offline Mike

  • Member
  • Posts: 999
Re: Two year follow up
« Reply #4 on: December 01, 2016, 05:12:14 pm »
I just completed a fibroscan, which was painless and only took about 5 minutes.

My results fell within the normal range for those without liver disease, meaning that my liver has rejuvenated over the past two years to the point of being detected as  normal by the fibroscan!

Best wishes, Mike
Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014

Offline dragonslayer

  • Member
  • Posts: 873
Re: Two year follow up
« Reply #5 on: December 01, 2016, 05:41:41 pm »
Mike, Thats such great news.. I have just one word for you:


CHEERS!!!    :D

and

Mazel Tov!!!!
« Last Edit: December 01, 2016, 06:02:03 pm by dragonslayer »
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline Lynn K

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  • Member
  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: Two year follow up
« Reply #6 on: December 01, 2016, 09:13:44 pm »
 That is great news Mike congratulations!  What an amazing organ the liver is
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline I fightis thetitis

  • Member
  • Posts: 129
Re: Two year follow up
« Reply #7 on: December 02, 2016, 02:13:59 am »
I just completed a fibroscan, which was painless and only took about 5 minutes.

My results fell within the normal range for those without liver disease, meaning that my liver has rejuvenated over the past two years to the point of being detected as  normal by the fibroscan!

Best wishes, Mike

Wow that is awesome! Congradts Mike!

I did not read through any of your earlier post. what stage of fibrosis were you?
You must be very happy.

Best always,
Greg
M59  56@start of TX. date infected:1976
diagnosed 1997 - asymtomatic
Genotype 1a
AST 111 -ALT 124 - AFP -89
Viral Load 1900000 - Log 6.28
Fibro Test F4 ActiTest A3
Harvoni 24 wks - start date 11/24/15

6 Week Labs VL Undetected!
104 weeks EOT Undetected.

8/25/17 Fibrosure score 80 = F4
11/10/17 Fibroscan 7.5 mean 1.6 m/s = F2
8/2018 Ultra sound normal.

Offline I fightis thetitis

  • Member
  • Posts: 129
Re: Two year follow up
« Reply #8 on: December 02, 2016, 02:15:17 am »
Never-mind- I just saw you were grade 2.
M59  56@start of TX. date infected:1976
diagnosed 1997 - asymtomatic
Genotype 1a
AST 111 -ALT 124 - AFP -89
Viral Load 1900000 - Log 6.28
Fibro Test F4 ActiTest A3
Harvoni 24 wks - start date 11/24/15

6 Week Labs VL Undetected!
104 weeks EOT Undetected.

8/25/17 Fibrosure score 80 = F4
11/10/17 Fibroscan 7.5 mean 1.6 m/s = F2
8/2018 Ultra sound normal.

 


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