Hepatitis Forums

Hepatitis C Main Forums => On Hepatitis C Treatment => Topic started by: CE on November 20, 2014, 07:13:48 pm

Title: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on November 20, 2014, 07:13:48 pm
I am a 60 yr. old female and I was diagnosed with HCV in July this year after my doctor found my liver enzymes elevated (ALT 170 and AST 106) with a routine blood test. This just blew my mind! Never in a million years would I have thought I had this. I either acquired it in 1978 or 1988 with blood transfusions after childbirth. I am genotype 3 (yay, of course it has to be the worse one!), and my viral load was 950,000. I started treatment Nov. 1st with Sovaldi and 1200ml Ribavirin for 24 weeks. I am about to complete week 3. At week 2 my ALT was down to 57 and AST down to 43, and my viral load dropped to 667! I really had no symptoms until 3 days ago. I had a low grade fever (100) and just felt cold and achy like I was getting sick. Fever was gone by morning, but then my chest hurt sporadically in different locations and my heart felt jumpy! That is gone now, but I still get chilled easily and am feeling more tired. When I think back, there were signs in my health that make sense now. I suffered anxiety and panic attacks, I would get unexplained rashes and hives, along with other "weird" ailments! I am so very determined to rid my body of this evil. I just hope that this treatment works on my genotype the first time. I was fortunate to have insurance that covered the majority of it and a co-pay assistance for the remainder. I work full time in a hospital materials management, and I have to remain sharp! I hope I can persevere with the side effects and become SVR by next July. I am thankful to have found this forum. Reading the experiences of others is very comforting and provides hope. I thank God everyday for my family and many blessings and pray for strength to endure.  It will be a long winter! God bless all!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Doluska on November 20, 2014, 07:34:57 pm
Good luck with your treatment! I am week 5 with Sovaldi/olysio and Ribaverin. It is not an easy jorney, but we need hope to continue and support from our close circle! This forum is very professional, optimistic and supportive. You are in the right place! D.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on November 21, 2014, 09:26:01 pm
hi c.e.
   today i took my last pills of 24 weeks.drink plenty of water, and exercise. i have never felt the immediate mental reward of deep breathing an d exercise, like i have felt while on these drugs.these  last couple of weeks i have been on intermittent fmla, i am in sales and just a little support helped me with stress, and my memory loss from the pills.the interesting thing is, a memory of self is getting stronger than its been for years.paranoia, and anxiety has plagued me for years getting stronger as my viral load skyrocketed.now, i remember things  with less emotion and being 56, am forgiving myself for silly mistakes until these pills are out of my system with the hep c.most importantly, evercise will help with aches and pains. drinking volumes of water and soups as my doc would say, helps with dehydration which can cause utis  which can cause low grade fevers, which i had in the beginning. anyway i worked overtime for most of these months , but needed to slow down at the end, you can and will DO THIS!!!  GOOD LUCK and post your fears and successes.we love to share...i am a girl too.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on November 21, 2014, 10:10:17 pm
Thank you Doluska and Zeena for your encouraging words. I just refilled my week of meds. Amazing how each day of meds means a step closer to being healed. I have been drinking so much water, I know I must have resized my bladder! Lol!
Good luck to both of you, too. Zeena, congrats on completing your course. Keep posting to let us know how you are. Hope you get the best news there is to hear in a few months! Take care.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on November 22, 2014, 03:31:45 pm
Hi CE,
I am also on week 4 of Solvaldi /ribra for geno 3.... And the same age! I love what you said being a step closer to healing, I have to remember that on my down days. I wake up every morning not knowing how I will feel, I am doing what the wiser members say and that is to drink plenty of water. I try and exercise every day no matter how I feel, like you I am determined to slay this dragon, I have had it for to long and I no longer want it in my body. I try and focus on a life free of this and all the possibilities it brings.
Keep me informed, it will be good for me to have another traveller on this path to recovery.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on November 22, 2014, 03:56:10 pm
Hi Francis60,
We do have a lot in common right now for strangers! Of course we are no strangers to this demon. Genotype 3 is the rarer, difficult type and it seemed that there were not too many folks with this. That is why I started this forum with that info first. I figured it would attract birds of a feather! Please do stay close as we battle the dragon! Good luck and God bless.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on November 28, 2014, 06:31:34 am
Hi,
Just got my 2 week VL back it is at 51...the doctor was expecting it to be undetected, any one else had a 2 week reading out their?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on November 28, 2014, 09:36:55 am
nope, 4 week was the first UD. still felt all beat up physically at 2 weeks.sounds like a good number though, the virus is going down the drain.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on November 28, 2014, 02:48:20 pm
Thanks Zeena, I can relate to "being beaten up"....lol
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: lucky-in-lasVegas on November 29, 2014, 02:41:19 pm
genotype 3 is the hardest to treat? I thought genotype 1 was? I am geno 3, My viral load is 9mill, fribosure bood test said  I am stage one liver damage, so my doctor says I can not get treatment until I am stage 3, does this make sense to anyone, in the meantime I am infectous to my family!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on November 29, 2014, 05:09:38 pm
Geno 1 use to be the hardest to treat but with all the new drugs it's now become the easiest. There are not as many geno 3s around so not as much  money has been thrown at it. But it's changing:)... That's my understanding of it. There are much more knowledgeable people on here than can help you . Good lucj
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on November 29, 2014, 09:21:37 pm
Hi Lucky,
Genotype 3 is the now the hardest because if the new drug treatments mostly aimed at genotype 1 as Francis said. But lucky for us all, it is a new and fast growing era of new hcv drug tratments. If you ever had to pick a time to have it treated, this is it. 24 weeks of Sovaldi and rbaviin is cake compared to 48 weeks with interferon and riba. I think it is totally insane to tell a person that they have to be "sicker" to get treatment. That should not be an option. I did not have any scan or biopsy. My history of post surgical bleeding made biopsy dangerous, and there is no fiberscan available in my area. All I know is I wanted this out of my body at any cost! My specialist wasted no time in setting up my treatment. If I were you, I would seek another doctor. After all, it is your health at stake. Please don't accept that decision. I hope you are able to find the way to treatment soon. Best wishes.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: badbradley on December 01, 2014, 02:44:12 am
Hi,
Just got my 2 week VL back it is at 51...the doctor was expecting it to be undetected, any one else had a 2 week reading out their?
Hey Francis,   I see your on this thread, What was your last alt/ast enzyme levels?           brad
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on December 01, 2014, 02:48:55 am
Hi Brad,
My Alt after 2 weeks had dropped to around 33. It was over 300 when I started.All my other blood work was within normal range.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: badbradley on December 01, 2014, 03:05:44 am
Francis, That is a significant drop and a positive sign that the meds are doing what they're supposed to! A VL test at 2 wks. is a curiosity check for Docs. They want to have a looksee to see if meds are working. It's not cause for alarm that it's still detected at this early in treatment. I didn't have a VL test until 4 wks in. My Alt was 23 at 2wks. Your Alt is in the normal range so personally-Iwouldn't worry at this point. I am geno 1a. I understand where you might be a little more concerned with geno 3 but I think it's too early for worry.   Best wishes - Brad
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on December 01, 2014, 03:11:01 am
Thanks Brad, I will know m one month in 2 weeks time, will keep you posted.
Take care
Francis
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on December 01, 2014, 04:55:31 pm
Hi all,
Just got my 4 week test results, (it actually was 24 days because of the holiday). My ALT is 28, AST is 29, but my VL is 63. It went from 950000 to start, down to 667 at 2 weeks. I have to admit, after hearing everyone talk about being undetected at 4 weeks, I am disappointed and worried that I won't be cured. Also, my HG is down to 10.3. Not good, although I am not really suffering any bad fatigue or other symptoms. Did anyone else have a VL at 4 weeks and still go on to be cured? Also, what foods can I eat to up my HG? I really don't eat red meat. Should I start chomping it?
Thanks for any help.  Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Doluska on December 01, 2014, 05:12:38 pm
Pomegranate, backweet, spinach
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on December 01, 2014, 08:40:29 pm
Hi Chris,
I went from 1,700,000 to 110 in one week to 51 in 2 weeks, I am waiting on my one month results, and will let you know. I was  hoping to be undetected after 2 weeks, but I was told its still early days, 20 more weeks to go.I have heard of other people with a VL after 4 weeks and still cured.
good luck
Liam
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on December 01, 2014, 10:32:02 pm
doluska, i didnt know pomegranite was good for us, i have been craving it, and eating the fruit, which I never liked before.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on December 01, 2014, 10:35:36 pm
CE.
   My hemoglobin dipped, and then turned back up while i was still on riba 1000 a day and sov.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on December 01, 2014, 10:37:14 pm
CE
 24 sounds more like 3 weeks. and that dipped alot from 2 weeks!!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Doluska on December 02, 2014, 07:43:02 am
Hi Zeena! See, sometimes our body is talking to us on it own way!!! Good luck and us usual, SVR forever!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on December 07, 2014, 11:11:39 am
Hi geno type three and riba ragers,
                            Its been 2 weeks post meds. and I am getting stronger everyday.My mental confidence is better than ever, and I am working overtime due to the holidays.Where there was confusion under riba, I now feel the initial confidence that put me in my job 20 years ago.I still crumble under sadistic management techniques, but I dont drink anymore, so the personal pain dissapears and my confidence moves in.Yes it is all in our head, unfortunatly we share our head with hep c and riba, for a time, and this too will pass. I wish all of you a speedy and safe svr.Another point, I wanted to know my svr early pre x-mas. Now I feel healthy enough it doesnt matter. I am so pleased with my thinking and organizing skills now, which were nearly  impossible under the meds.I may wait for 12 weeks to see, but my point is I am functional and feel great!!this to me is healed.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on December 07, 2014, 11:33:05 am
Wonderful news, Zeena! We all have so much to look forward too!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on December 07, 2014, 05:03:46 pm
Hi Zeena,
I just woke up with a heavy Riga head, and reading your email picked me up no end.
It is so inspiring to hear what you have said, enjoy your new life. And thanks again for making my day.
All the best to you ...well done
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on December 07, 2014, 08:32:59 pm
and thank you francis 60 for making mine!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kelly on December 08, 2014, 10:44:11 am
I just have to say thanks to whoever it was that posted the information about emailing express scripts!  I emailed them this morning at 6 a.m. and just got a response from a really super nice lady named Liz.  She told me she is working my case for Harvoni and that she would have an answer for me by today at 3:30!!!  My son was diagnosed back in July with Hep C when he entered the military.  He was discharged soon after and sent home.  We sought care from a gastro doctor here and he said he wanted to wait to start treatment until Harvoni became available.  Well, he prescribed it for him right around Thanksgiving or soon after and we were DENIED.  He asked if he would file an appeal for me and he said he did not have "time" due to "patient needs".  WOW.  So, we are seeking help from the Liver and Wellness Center tomorrow and will see what this doctor does for us, as well as express scripts.  I can't believe it.....prayers he will be on Harvoni soon.  He is 21 years old.  :)  Thank you for this very informative forum.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: BattleTheBeast on December 08, 2014, 10:51:52 am
I just have to say thanks to whoever it was that posted the information about emailing express scripts!  I emailed them this morning at 6 a.m. and just got a response from a really super nice lady named Liz.  She told me she is working my case for Harvoni and that she would have an answer for me by today at 3:30!!!  My son was diagnosed back in July with Hep C when he entered the military.  He was discharged soon after and sent home.  We sought care from a gastro doctor here and he said he wanted to wait to start treatment until Harvoni became available.  Well, he prescribed it for him right around Thanksgiving or soon after and we were DENIED.  He asked if he would file an appeal for me and he said he did not have "time" due to "patient needs".  WOW.  So, we are seeking help from the Liver and Wellness Center tomorrow and will see what this doctor does for us, as well as express scripts.  I can't believe it.....prayers he will be on Harvoni soon.  He is 21 years old.  :)  Thank you for this very informative forum.

Kelly,

That was Lynn that shared the ExpressScripts email address. I was able to get right through the red tape by using it myself and started Harvoni on Saturday.

I hope it goes the same for your son and he is able to find a supportive Dr to work with. As we have all learned not all doctors are the same.

This forum and the members are truly a blessing for all of us.

Mel~
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kelly on December 08, 2014, 10:58:02 am
Thank you, Mel!  I told the lady at Express Scripts that I did not want to have to involve the former gastro in any of it so I'm not sure if we will have to have an active prescription or not....which I guess we could always get tomorrow.  I'm new to all of this and had no idea what to do or where to go until this forum.  I could not believe the doctor did not want to help and I'm super glad we found out early rather than him monitoring his treatment all along.  My son hasn't really done any research on Hep C and I personally feel like he tries to block it from his mind that he actually has it.  I'm sure at his age he doesn't even understand what could happen to him in the future.  I am the one with most of the questions and concerns at this point and am fighting hard to get a good treatment plan that will allow him to work and function each day.  Are there certain foods he should be eating or avoiding that will help him cope?   We believe he got his Hep C from a tattoo, or at least that's what he wants to fess to me so far.  :)  Not important how he got it at this point for me.....just want him cured.  Prayers for all who are going through this. 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: BattleTheBeast on December 08, 2014, 01:48:07 pm
Hey Kelly,

It's amazing that you agree it really doesn't matter where it came from, he has it and he is going to get cured. You are a good mom!

I'd google a liver friendly diet, there are things that help and clean eating without processed foods is important. I am fairly new to the diagnosis myself so still learning. I do know that drinking lots of water is important. There are many here who will be able to provide you with way better advise that I can give you.

Perhaps if you tell us the closest metro area to you someone here will have a doctor they can refer you to.

Mel
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kelly on December 08, 2014, 02:50:49 pm
Thank you, Mel.  I have seen a lot of people talking about drinking water.  We live in the little rock Arkansas area.  We are going to the liver wellness center tomorrow.  Got called this afternoon by the prior gastro and was told that solvaldi and olysio were denied as well.  Express scripts called a bit after and said they have contacted the wellness center and faxed paperwork over to start the appeals immediately. Hoping to have answer by end of week is what she said.  Please keep praying for treatment on harvoni!!! 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kelly on December 08, 2014, 02:51:55 pm
He doesn't eat much as it is now but I will research a liver friendly diet! 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: BattleTheBeast on December 08, 2014, 03:35:44 pm
Hey Forum Members,

Anyone have a great doctor in the Little Rock Area to recommend? I know we are spread all over the world but you never know.

Kelly's son could use a doctor who cares!

Thanks,

Mel
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kelly on December 08, 2014, 03:38:41 pm
Thanks again Mel!!  So far I've heard great things of who we are seeing tomorrow.  Let's keep our fingers crossed.  If I don't get a good vibe then that one is out as well!! 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on December 09, 2014, 03:00:04 am
Hi Mel

Thanks for sharing the address with folks. That was my hope to help folks get around the red tape. I am so glad it is working for people.

Actually Liz is the same person I spoke with as well small world that connects us all.

Lynn
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: BattleTheBeast on December 09, 2014, 07:57:56 am
Hi Mel

Thanks for sharing the address with folks. That was my hope to help folks get around the red tape. I am so glad it is working for people.

Actually Liz is the same person I spoke with as well small world that connects us all.

Lynn

I had a young man named Jason and I have a direct number to call him should the need arise!

We are fighters if nothing else!

Mel
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kelly on December 09, 2014, 12:48:42 pm
That's awesome, Lynn!  Maybe your luck will rub off on me!  She sounds absolutely wonderful to deal with.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Krissy on December 10, 2014, 03:09:25 pm
CE,

I recently finished the same treatment for type 3 and I am so happy to report that my end of treatment blood work came back undetected!! I was undetected at 4 weeks too. Now I wait 3 months to see if I have a SVR. I'm feeling pretty positive about it though.
The treatment was really not too bad for me. The worse side effect was insomnia. I used Ambien a few nights a week and that really helped.
Best wishes on your journey!
Krissy

Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on December 10, 2014, 04:24:23 pm
Hi Chrissy,
Congratulations, it must be a wonderful feeling.Love hearing these reports, I get my results back for my one month tomorrow morning.enjoy your hep c free new life. Please keep us updated.
Cheers
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on December 10, 2014, 04:55:50 pm
Krissy,
A big high 5!! So happy for you. My 4 week blood work was done at 3 1/2 weeks and I still had a vl of 68. It depressed me, but I was told not to worry, that it does not mean I won't have a svr. I feel ok, but feel a bit tired during the week after work. I do have a funny cough. I cough when I take a real deep breath, whatever that means. The riba has my HGB down to 10.3. I just had my 6 week labs done, but not for vl. I won't get that until my 8 week. I hate all the suspense! Lol! I do hope my treatment works. As for you, I will keep you in my thoughts and prayers that you keep the SVR FOREVER!! Best wishes and keep us posted.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kelly on December 10, 2014, 04:59:15 pm
Hey Krissy!  Thanks for your response,  not me though that has SVR!  We are waiting for that day!  Still pending approval for my sons harvoni.  I'm sorry you still have sighns but hang in there and I promise it will happen.   Patience and prayers!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on December 11, 2014, 10:38:10 pm
Hi all,
Just got my 4 weeks blood work back am still detected VL 15 it was 68 after 2 weeks,
My hgb has dropped from  150 at baseline to 132, not sure if that is good or bad and my ALt  is 23 it was 390   4 weeks ago, my energy levels are ok but was hoping to be undetected already. Feel a little disappointed, I guess I am posting to  hear some other opinions on these numbers. I Am on a clinical trial and my doctor is not very forthcoming with explaining results to me .
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on December 12, 2014, 10:22:12 am
my understanding,is your doing great!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Picnic on December 12, 2014, 11:05:58 am
Definitely going in the right direction!! Be patient, it will go UD on the next one!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on December 12, 2014, 12:10:14 pm
You faired better than me! At 2 weeks, my vl was 667, 3 1/2 wk it was 68. I dont get another VL test until 8 weeks, so I dont even know if it's UD or not. I know exactly how you feel with the disappointment especially after hearing everyone else saying they were UD at 4 weeks. My doctor's nurse said not to worry that my body was responding, and that's good. My hgb was down to 10.3 at 4 weeks. I never called about my results this week for the 6 weeks. I figure no news is good news. I basically feel ok, just more tired after work during the week, but on the weekends, I don't get tired!
Hang in there, Francis60. You are my soulmate right now. Together we will battle this beast!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on December 12, 2014, 04:04:50 pm
thanks CE....keep me posted on your results....yep we are in this together!. Take care
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on December 30, 2014, 12:30:18 pm
Just got 8 week blood results. All liver enzymes are absolute normal, bili good, hgb still low but recovering, but best of all, VIRUS UNDETECTED!!!! 16 more weeks to go. A perfect ending to this year!
Happy New Year to all and may you all be blessed with SVR!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on December 30, 2014, 05:27:15 pm
Hi CE,
Congratulations fellow geno 3 ...24 weeks:)... Yes the new year is looking good. I get me 8 weeks results next week. Do you know what your hgb was?
Enjoy your new life and year.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on December 30, 2014, 05:46:44 pm
My HGB dropped to 10.3 at 4 weeks, but has went up to 10.8. That is really low, but I feel good and the doc is confident it will continue to rise now. I eat lots of green leafy veggies, especially spinach and Trying to eat more red meat. (I was not big on red meat) i look forward to the great report you will get soon too! Happy and blessed New Year!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: BattleTheBeast on December 31, 2014, 05:31:56 pm
Great Amazing Fantastic news CE!!!

Francis,

No worries, I too was still detected at 4 weeks and happy to report as of a week 9 blood test I am also Undetected, New Years Day I start week 13. I saw my IDhero today and he said that I looked human again, may sound like an insult but it was an amazing compliment considering how rough I have looked and felt for almost a year. I just know if you were at 20 @ 4 weeks this one will be undetected!

Keep doing what you are doing, take your meds the same time each day, drink lots of water, rest when you need to (it's ok, this medicine is strong stuff).

Happy New Year to you both and SVR in 2015 for us all!!!

Mel
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on December 31, 2014, 06:02:06 pm
My VL was at 68 at week 4. They skipped week 6 count, and UD at week 8. Not really sure when the exact moment was that I was UD. As for looks, I know I look rough around the corners! Lol! When you think of the battle our bodies are going through, and the nasty meds we're consuming, it's no wonder. I really can't wait to feel that "burst of energy and brightness" that every one that is SVR has experienced. 
Have a very happy New Year, and may the new year bring us resounding good health and new life! God bless!
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on January 03, 2015, 11:45:26 pm
Hello, I've just joined this forum, and so glad I found it, as here in Aus I live in the country and cannot access any support groups, that may be able to address my concerns regarding side effects of the Sovaldi/Riba combo.

12 wks ago when I began tx, I was initially prescribed 1000mg of Ribavirin (and 400mg Sovaldi). Within 3 wks my Hemaglobin had decreased from baseline 13.7 to 9.2. My hepatologist reduced my dose to 600mg - and I must add, there is not much of me, I weighed in at 51.3kg at baseline. He said, that despite the fact that I had become quite anaemic, this was a good indicator of successful tx, as it indicated that my blood was thoroughly saturated with the Riba. I was relieved to reduce my dose, if it was going to make me feel better, as my energy, mood etc all were very affected. By wk 6 my haemoglobin increased to 10.4 and has stayed so since then. My hepatologist said if it rose to 11 he would increase my dose of Riba, and I am now quite comfortable to be able to withstand a dose increase.

My concern is, will 600 Riba, since wk 3, eradicate the virus? Would anyone on this forum be able to answer this?

Btw, all my blood tests (except Hgb) have moved within normal range, though my platelets, although within range, are still regarded as low by the lab - sitting on 210.

Wishing you all a happy healthy virus free New Year!
Jazz
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on January 04, 2015, 12:09:30 am
Hi Jazz,
Welcome to the forum, I am also on the same treatment week 10 undetected.there are some very knowledgable people on this forum that I am sure will be able to assist you. Are you from Australia ? 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on January 04, 2015, 01:00:19 am
Thank you for your greeting Francis
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on January 04, 2015, 01:02:13 am
Hmmm, didn't include the rest of my msg. Yes, I live in Australia, where it's very hot at the moment!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on January 04, 2015, 01:14:43 am
I am on the riba/solvaldi 24 week trials in Melbourne. Yes it is very hot.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on January 04, 2015, 02:15:42 am
Hi Jazz,
Welcome to the forum! Ribavirin is dosed by weight and 1000 seems pretty high for your low weight. I could be wrong though as I am not an authority on the matter.
My hgb dipped from 14 down to 10.3, but at week 6 increased back to 10.8. That was scary as I did not want to take Procrit or have a transfusion. One good thing is you are half way thru treatment! Congrats. I just began my 10th week today. I have had only a few effects along with the low hgb. Twice I ran a low grade fever and felt cold, my skin and hair is more dry, and my eyes feel dry. Also, get tired on some days.  I drink lots of water and try to eat healthy.
Good luck to you and please let us know your progress. Happy New Year!
Chris

Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on January 04, 2015, 02:47:23 am
From the Sovaldi prescribing information sheet

https://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/sovaldi/sovaldi_pi.pdf

Dose of ribavirin is weight-based (<75 kg = 1000 mg and ≥75 kg = 1200 mg). The daily dose of ribavirin is administered orally in two divided doses with food. Patients with renal impairment (CrCl ≤ 50 mL/min) require ribavirin dose reduction; refer to ribavirin prescribing information.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on January 04, 2015, 03:08:07 am
Thanks for the replies and welcome Chris and Lynn.

I agree with you Lynn 600mg is probably enough for my weight, and as my doc says, my blood is saturated with it so, it is doing the job.

I realise there would not be a great deal of stats on this, as this combo is still relatively new. If the trial I'm on didn't allow a reduction of Riba dose, I would have ceased the Tx, as I was very breathless, fatigued and tearful on the 1000mg, and generally could not function.

I shall be watching everyone's progress with interest and hope we all successfully clear this virus once and for all!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on January 04, 2015, 03:09:14 am
Sorry, I meant, 'I agree with you Chris'
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on January 04, 2015, 03:37:42 am
Hi Jazz

This is a link to some clinical trial results for Sovaldi riba with 250 genotype 3 patients

For the treatment naive the results were 94% so looking good!

http://depts.washington.edu/hepstudy/presentations/uploads/93/valence.pdf
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on January 04, 2015, 03:42:45 am
Ah yes, thanks Lynn, I have seen the results of this Valence trial - looking good indeed!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: amh on January 20, 2015, 09:08:02 pm
I too am in my late 50s (when did that happen?)  and have had Hep C probably for about 35 years.  I have geo type 3 with a VL in the high range.  According to my DR my liver is functioning normally and my ultrasound was normal.   
I was approved for a 24 week treatment of solvadi/ribaviran today.  I've already spoken to the pharmacy and will have my meds sometime next week. 
I am very apprehensive about beginning treatment.  I have a demanding and stressful job and I need to work throughout the course of my treatment. I do not want my job to know I am undergoing treatment for HC,.   I work in HR/benefits so if I applied for any FMLA I would have to disclose to my co-workers and I would like to avoid that if it all possible.   it is very encouraging to read other people's stories who have and are going through the same thing I am going through.  I wish you continued success on your journey and want you to know how helpful your posts are to those of us who are about to start on their journey.


Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on January 20, 2015, 09:18:53 pm
I don't see why you would need to disclose the nature of your medical condition to anyone not even you direct supervisor. All they are allowed to know is your are taking a Medical leave for all they know it could be to care for an ailing parent, child or spouse. I have been on FMLA a couple of times and only worked with the approval department. I do work for an very large company so an outside entity handles our HR and FMLA and other functions. But still I believe HIPPA protects you right to privacy.

But in any case many here have done treatment with Sovaldi and Ribavirin and worked continuously throughout their treatment including those with physical jobs. Ans those that were so inclined continued their work out routines. Most have reported mild side effects so I really believe you can make it through.

The time I took 2 weeks of FMLA I  was treating with Interferon and Ribavirin and that combo caused my hemoglobin levels to become very low. But that is not so much a concern with Sovaldi ribavirin.

Good luck on treatment. You can do it!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on January 20, 2015, 09:58:22 pm
Anh, I too work a very stressful job. I am a buyer for a hospital. I am known throughout the hospital. I absolutely refuse to tell anyone there what I have. I travel to another hospital to have my labs done. I have to pay more since it is something that can be done at my work place, but it is worth not having everyone talking behind your back. Trust me, I have seen it happen to other people. I did tell my boss that I am on some medicine, and it can make me tired, and that is it! But so far, 12 weeks in, I am as alert and productive at work as ever. Never had to miss a day! So, relax, and take it day by day.   :)   Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on January 21, 2015, 02:04:43 am
Anh, if I hadn't become so anaemic so rapidly at the beginning of my treatment, I would not have experienced any fatigue. Now at 14 wks, I am still anaemic but my body has adjusted to it and I am as productive as always with no side effects to speak of, except for the fact, that I am bit more quiet than usual. If my experience is anything to go by, you will be fine. All the best to all for our mutual success!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on January 21, 2015, 04:19:58 am
Hi Amh,
I am on 12 weeks of 24 riba/sol and besides so fatigue and minor skin rashes it has been ok. You can do it. Welcome !
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 04, 2015, 10:53:52 pm
Trudging through my 14th week of 24. I'm not gonna lie, this week has been one of my worse weeks. I've been irritable, bit off a few heads, and I look like crap. My skin is pasty and I have sullen eyes. The concealer is struggling to make me look healthy. I'm not sure if it's the lack of sunshine or the riba that is giving me a lower tolerance towards people who irritate me. I decided to use some PTO and take a long weekend. Some much needed time off work. It has been very stressful lately. I plan on doing NOTHING for 4 days! All R&R. I hope this makes for a nicer me next week!
Best wishes to all in the same boat! Take care and keep on trudging! We will eventually make it!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on February 04, 2015, 11:21:37 pm
Hi CE,
I know exactly how u feel also on week 14 and it's been my worst..... By far.been in such a dark space, this is the first day I have felt a little bit better. I look like I havnt slept for a week. We will get their.!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on February 05, 2015, 02:07:17 am
Ditto. I'm on my 16th week and I'm soooo fatigued, drugged and, yes, the fatigue and achy joints ( a new side effect I have developed in the last week) are really quite depressing. I have to summon all of my positive energy (!! did I say energy?) to stay afloat.
I mark off every week, so now I only (!!) have 8 more weeks to go. I would stop sooner if I could be certain the virus has been eradicated, but we don't know that for sure til 6 mths end of treatment. Catch 22.
We must all hang in there and have a good grizzle here when necessary.

All the best fellow patients,
Jazz :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kate0b1 on February 05, 2015, 11:23:59 am
@Ce,jazz and Francis I'm sending you lots of positive thoughts for the w/e, Im not on riba this time but i'm cringing remembering the terrible feelings, i'm so sad anyone has to go through it  :'(. Ce, i hope your 4 day R&R gets you back to a better place, i think naps could help! and come here to vent if you get ragy, we can listen at least and understand.  8)

kate
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Long_Haul on February 05, 2015, 11:32:42 am
Sorry to hear Ribavirin is taking it's toll on you guys, you can do it. I did 48 weeks of Interferon and Ribavirin. I still can't figure out how I made it through without my wife taking a contract out on me. Keep your eyes on the prize and you will make it!

Hang in there,

AL

Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 05, 2015, 04:24:39 pm
Thanks all for your unconditional support! It really makes a difference when you can relate what you are feeling and there is someone that REALLY knows how you feel! As Long Haul says, we need to keep our eye on the prize! Best wishes!
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on February 05, 2015, 06:53:56 pm
Yes, I second CE's thanks, and Long Haul, you put the biggest smile on my face with yr joke about the wife and contract! Very funny!

Eye on the prize! We can do it! Yes sir!

All the very best to all,

Jazz xx
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on February 05, 2015, 07:26:13 pm
Same here. Gen 3 S&R for 24 weeks. I just finished my first month yesterday and already my enzymes all plummeted to normal levels and my viral load dropped significantly. I resisted interferon hoping for something better to come along and it finally did. Glad too because I was in the fatty liver stage, nearing cirrhosis, and wasn't sure how much longer I could hold out.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 05, 2015, 08:01:01 pm
Welcome, Billy! You are in the right place with the most supportive people ever! Congrats on your progress! Someday soon this dragon will be history for all! The very best to you!
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on February 05, 2015, 09:16:52 pm
Thanks!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on February 05, 2015, 09:22:00 pm
Yes, welcome Billy. That was the case with me, enzymes back to normal, VL undetected at 4 wks, it really is remarkable and I tend to forget all this when I'm so fatigued from the treatment and the anaemia I have developed due to the Ribavirin - doesn't happen to everyone, 10% are affected this way.

Don't be put off by my moaning, energy levels on this stuff Have their troughs and then, viola! the next day after a trough, you don't feel so bad after all.

I waited, like you, but boy, am I glad something Interferon free came my way, as my liver disease was progressing too.

Apparently the fatty liver resolves itself after successful treatment as does fibrosis, and even Cirrohsis, so I am hearing and reading. So it's all looking good for us!

All the best, Jazz
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on February 05, 2015, 09:49:21 pm
Yeah they felt I could becoming anemic as well and reduced the ribavirin  from 6 to 5 a day. Hope that doesn't throw a wrench in the gears..
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 05, 2015, 10:07:37 pm
My HGB went as low as 10.3 in the first month! It is staying between 10.5 and 10.8 now, which is really low, but the doc says it has to go below 10 before they will treat it. And they would either give me Procrit or a transfusion (the very culprit that gave me this 35 years ago!). I want neither. Lowering the riba was never mentioned. I hope it doesn't go any lower. I'm trying to eat more iron rich food, and orange juice to help absorb the iron. Under eye concealer is my friend. I will just shuffle along for the next 10 weeks. Cheers to all with a big glass of sparkling water!
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on February 05, 2015, 11:18:47 pm
Hi all,
Chris and Billy it's not iron deficient anaemia unfortunately, it's haemolytic anaemia - the Riba is knocking off our red blood cells before they get to maturity, so we are deficient in heme, so iron rich foods won't really make much of a difference. But don't worry, my Hemaglobin went down to 9.2 in 2 1/2 wks into treatment and now oscillates anywhere between 9.5-10.5, what my treatment team call 'stable anaemia', and will go back to normal btw 2-4 wks after treatment.

Just pace yourself, don't over do it, and you should be fine.

Btw, anaemia means our blood is saturated with Riba, so don't be worried if your doc insists on lowering your Riba dose, as if you stay anaemic, that means you are getting more than enough. And the trade off for feeling extra fatigued on treatment, is that Riba induced anaemics have high odds for clearing the virus, as Riba is killing anything that moves!

Cheers, Jazz
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on February 05, 2015, 11:53:43 pm
Welcome Billy,

Please keep us updated with your progress. We are going to all beat this!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on February 06, 2015, 12:01:16 am
Yes we are! I'm feeling very good about it. Very impressed with how fast the S&R works.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 06, 2015, 09:57:51 am
Thanks for the great info! I had to chuckle at the "riba is killing anything that moves"!!   Gives me hope though that all our misery will not be in vain.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on February 06, 2015, 07:09:11 pm
I do feel better today taking one less riba...slept better too.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 10, 2015, 07:44:21 pm
Returned to work today after 4 glorious relaxing days. Felt totally refreshed. And a good thing I did. Within 30 minutes of the start of my day the serenity fell apart as multiple departments pounded me with their problems. At least I was rested enough to bear it and even managed to lighten their turmoil with some humor! I think my shoulders were a few inches wider at the end of the day! Lol! I can only imagine my incredible energy to look forward to after the EOT! Bring it on!!
Hope all are doing well and keeping the battle strong!
Best wishes. Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kate0b1 on February 11, 2015, 06:11:04 am
@chris,  im glad you had a great R&R, i thought your shoulders sounded a little wider lol, I'm glad you are feeling better/stronger ;)

kate
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on February 11, 2015, 06:25:36 am
Yes Chris, good you are feeling refreshed.

While I've become even more anaemic! Most recent blood tests have my Hgb at 9.1. But to be honest, if they pull me off the trial at this stage - this is my 17th week - I won't be sorry. There is plenty of data that suggests anaemia during treatment increases odds of success, as blood is totally saturated with Riba, as well I'm treatment naive. Anyway my body and the trial rules will make that decision for me, but I'm not concerned either way. Indeed I'm confident the virus has been eradicated by now.

Cheers all,
Jazz

Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 11, 2015, 12:30:16 pm
Jazz, i'm sorry to hear your HGB is so low. That riba is really attacking you. Perhaps they will just reduce it. You have come too far to stop. You got that beast by the butt! The best to you! Take care!

Kate, hope you are doing well. Honestly, this place was a hornets nest and today is not shaping up much better! Stress can't be good for us! Take care!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on February 11, 2015, 09:28:03 pm
hey y*all,
    been there , done that...stress enters new levels of meaning on riba and i now think sovaldi is a little to blame. keep your mantra of water and exercise,I messed up a couple of times drinking while on tx. paid for it with pain too! The pain in my side was prominent for a few days after my 2 mistakes.One time was a wedding, the other time was overworking and getting home soulspent. I didn t care anymore for a minute and opened a bottle of wine.Being in sales can leave someone healthy feeling used and discarded after a hectic day. To us on these meds? Well we all deserve medals. 24 weeks is a long time to pretend to be your normal self, especially if dipping in a cabernet was a way to relax.Today I got my 12 week undetectable post tx.There are many changes I feel. Calmer, more confident in my decisions.post hep c feels good . but its a kind of beginning  too, like discovering this new self, and finding out days can go by without wanting to drink because its o.k. just to be  whatever.my liver still feels sensitve, sometimes, but it could be I expect it too. whatever it is , you guys will be here on the day i am now, svr12  YES YOU WILL.stand back at the teeth gritting moments and laugh. drink a bottle of water join a zumba class.   enjoy the ride... the destination is worth it!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on February 11, 2015, 09:53:43 pm
Hi All

I am taking Harvoni for 24 weeks but my doctor added Riba part way in due to my treatment history and cirrhosis.

My HGB was 13.7 before I added the Riba but just 3 weeks later it has dropped to 9.3.

I am guessing I will be hearing from my doctor to reduce dose but for me the Riba is just an add on in case I need the extra percentage point to cure my hep c on this my 5th try at treatment. Hopefully I will be cured this time.


Just would like to add this information I found

http://www.rxwiki.com/askrx/4036/can-you-consume-alcohol-while-taking-harvoni

Harvoni, a prescription medicine containing ledipasvir and sofosbuvir, is used to treat chronic hepatitis C genotype 1 infection in adults.

You should avoid alcoholic beverages, not specifically because you are taking Harvoni, but because no amount of alcohol is considered safe for those with hepatitis C or other liver diseases. Any amount of alcohol can further damage the liver.

Just a thought
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 11, 2015, 09:59:44 pm
Cheers to you Zeena (with a bottle of sparkling water held up in the air!) So wonderful to hear you are SVR12! I SOOO look forward to the day! I want to see what I have been unknowingly missing all these years! Keep up the good work and enjoy your new life to the fullest! Keep us posted. Take care!
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on February 11, 2015, 11:36:28 pm
 i agree dont drink!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: db on February 12, 2015, 12:11:53 am
Hi I'm new to this forum was told today my Sovaldi approved with a out of pocket copay of 20 grand. I'm shocked and depressed no one c a new afford that any suggestions on what to do. I'm hoping for assistance thru Gilead
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on February 12, 2015, 02:00:06 am
Hi and welcome

Yes Gilead is a good option. What insurance and prescription drug provider do you have? Others with the same insurance may be able to provide suggestions.

Good Luck
Lynn
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jazz on February 12, 2015, 04:40:04 am
Thanks for encouragement Zeena.  :)

I haven't had a drink for some time and have not ever really been a drinker, but I must admit, when i get my 24wk SVR, I will be celebrating with a good red and a posh dinner!

Best to all,
Jazz
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on February 12, 2015, 08:59:11 am
dear Lynn,
      Sounds like riba has you in its clutches. I took 1000. riba though i am 125 pounds.I hope your levels go up,,Good luck, and after 5 tries I believe this is going to be the one.  Keep Laughing!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 12, 2015, 12:17:25 pm
Hi DB! Welcome to the forum! If you have insurance, you can get assistance with the copay through the Patient Access Network (PAN) www.panfounation.org. Check it out. They covered my copay in full. Very nice people too. Good luck to you! Best wishes.
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kimharvest on February 16, 2015, 04:51:02 pm
This is my first time on this forum. Hep C seems to separate one from everyone else; people say "It's OK with me" "Do I look ignorant?" "We are family...". But they all disappeared. I found out I had it in 2002, unfortunately my thyroid doctor missed all the high liver enzyme rates throughout the 90's. Took a ghetto clinic to notice those red flags. I wish I knew earlier because I shared razors sometimes with my daughter. I must have picked Hep C up in the 1970's. But the last few years I have been so incredibly tired and my mind was in a constant haze I couldn't fight through. I was lately down to just paying bills and nothing much more. I felt I was losing control over my life. Now I see here about Mind/Brain Fog and I can't believe how alone I have been in this. I swear I couldn't have gone on another year. I waited over 10 years for a new medicine. My VL was a few million then but now is over 8 million. All the blood surging through my brains had no room for nutrients just laden with virus. My tinnitus was horrid. I used to work on my farm 4-6 hours easy now 1 or 2 is too much. My house is a mess and nothing is organized. I work continuously on my art/hobby to keep producing and learning but at times seems like there is no future. Now I started on the Sovaldi and Ribavirin and I am at my three week point. I have symptoms like being bus sick; thick headed to headache, slight nausea, muscle tightness and some itching. I can actually feel every one of my hair follicles! I was feeling the promise of much more energy and my tinnitus shrill has lowered. There are good days and bad, probably dictated by food and water intake. I started crying the 2nd week but it wasn't depression as much as realizing how sick I was and how horridly it made me alone. The fog starting to lift had tears of, basically, joy! I quit drinking a decade ago, unless it was special... so Friday 2 weeks ago, I was in an exhibit and had a truly trying day and got a glass of wine during the show. Within 20 minutes I collapsed and was violently sick. Can't make that mistake again! Two week blood test showed my liver enzymes dropped 50 points. Now very upset how people are claiming S/R doesn't work for 3a. Hope to God that isn't true for everyone. Six months of this will be enough, I certainly hope they aren't blowing smoke up my ass.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 16, 2015, 05:19:09 pm
Hi Kimharvest. Welcome to the forum. You surely have been through a lot. But, you are in a good place now with people who all experienced what you have. It's really comforting to know you are not alone. It's interesting that you mentioned the tinnitus. I developed very loud tinnitus in Feb. 2013. That is the reason I went to the doctor. I had an MRI to rule out a tumor and had some routine bloodwork. That is when the high liver enzymes were discovered. The tinnitus is still there, but I'm used to it, but view it as a blessing in disguise to get me to the doctor. I also felt feverish and had chills in the first few weeks. Drink plenty of water as it does help with the headaches. I chose not to disclose my illness to my friends, co workers and extended family because I did not want that stigma of being contagious or dirty. I got mine in the 70's from a transfusion with the birth of my first child. Only my immediate family know what's going on. I do hope you are hearing wrong about the S and R not working. I heard it's at least 85%, better than past treatments. They have not been concentrating on geno 3 much. I hope that changes for those who need more treatment. Congrats on the drop in your enzymes! The meds are doing their thing! Continue to do what you physically can, it's ok to rest. The housework can wait! Your health is more important. And no wine! Lol. Water, water and more water. I like mine with a fresh lemon slice. Keep us posted with your progress and express any concern or ask questions. There is always great feedback. Take care!
Best wishes,  Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on February 16, 2015, 09:47:01 pm
While Sovaldi plus Ribavirin is not perfect for GT 3 per the clinical trial results you odds are about 85% overall 94% treatment naive and 79% treatment experienced while about 95% for treatment naive without cirrhosis and 92% for treatment naive with cirrhosis

It does work for GT 3. With the new meds formerly GT 1 was the most difficult now GT 3 is but still most GT3 patients do cure.

Conclusions: “Therapy with sofosbuvir–ribavirin for 12 weeks in patients with HCV genotype 2 infection and for 24 weeks in patients with HCV genotype 3 infection resulted in high rates of sustained virologic response.”

http://depts.washington.edu/hepstudy/presentations/uploads/93/valence.pdf

Hang in there and good luck
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on February 17, 2015, 10:59:59 am
hey kim
  yes yes and yes.KIM DRINK MORE WATER THAN YOU EVER WANTED TO!!! exercise. and it will be an easier ride.I went to the er because of dehydration in the first few weeks. i was so weak i had to be wheeled in, and i am not weak!had wine at my brothers wedding and felt like my liver would fail. ouch! by the time i started on the meds, i was getting unexplained rashes, and always tired, and paranoid !!I  dont remember when i found out but, i have had it since the early  80 s .I was at millions when i started too. our liver rejuvinates itself, so let the  meds kill the virus, and take care of yourself. i dont know why you think these meds dont cure 3 genotype, it did for me!as the spring brings new life to your farm, see that life also beginning in you!!i am happy now in ways i couldnt be before.btw, my husband and son are hep c free. you are being given a new chance at life with these meds Riba did a number on me, I was still running the show at home while fully medicated and working full time, there were moments when my voice reached decibals i hadnt heard since i was an angry teenager.HOW LUCKY YOU ARE TO BE INVOLVED IN ART. These meds work for geno 3!!  good luck
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on February 19, 2015, 08:04:42 am
Genotype 3 ,
My name is Lisa, and I am beyond scared to start my tx. .... there, got that out of the way. I am a tentative F4, rated through a Fibroscan imaging test. I have a 950,00 viral load. Also discovered a small cyst on liver. I so appreciate all of your posts and advise. I'm going to be 50 in a month and on last step of Sovaldi/Ribo med approval... so I should start tx soon. I have to work, in medical field, and have chosen to keep my health conditions private.... so knowing ahead of time kind of what to expect is very helpful. I'm worried. Nervous.  I feel side effects from things as simple as immodium for example, I cut all dosages of anything in half, and rarely have had to take even an abx for anything, thus I have myself so worked up mentally over this that I had to share my fears. I have little support.
Wish me luck, and God Bless
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on February 19, 2015, 08:09:07 am
Kimharvest and all,

I have tinnitus too. I'm going to ENT before starting tx. I'm used to it at this point, but it is a concern as Ive noticed it has gotten louder lately and I don't want it getting worse

Thanks. God bless and keep us
lisa
Genotype 3
F4
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: tinybim669 on February 19, 2015, 12:01:44 pm
Hello everyone i'm new on here but i have been reading posts on here for awhile. I just got done doing my first 4 weeks of 1 Sovaldi / 1200 mg Ribavirin a day (24 week treatment for G 3a treatment naive). I know i have only had HCV for 3-4 years. I have just received my 4 week results last night (A little birthday gift for my birthday yesterday).

Pre-Treatment

01/03/14
 Hepatitis C Virus RNA, Quantitative
Result: Detected
3229540 I.U./mL
6.51 log10 I.U./mL

08/06/14
 Hepatitis C Virus RNA, Quantitative

Result: Detected
2160612 I.U./mL
6.33 log10 I.U./mL

Sov / Riba Treatment
4 week Results
02/16/15

Result: Detected
< 12 I.U./mL
< 1.08 log10 I.U./mL

Range of Quantification: 12 - 100,000,000 IU/mL HCV RNA
Range of Quantification: 1.08 - 8.00 Log10 HCV RNA

I am close to defeating this beast.. ;-) The only issue i have had from the meds are bad heartburn in the morning and get tired a little earlier at night but other than that this is a piece of cake so far.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 19, 2015, 12:42:05 pm
Hello and welcome, LisaMarie and Tinybim! I found this a very supportive good place to be! You will too! First of all, LisaMarie, don't be afraid. I am so much like you in respect to being sensitive to any meds. I never took any OTC cold meds cause I would end up in the ER with palpitations! I am about to finish my 16th week tomorrow. I had very few sides. I also work full time and it has not affected my performance except for an occasional stress related irritability due to the ribavirin. Eat well, rest when you can, drinks lots of water, and stay tuned to the forum. You will do well!
Tinybim, Happy Birthday and congrats on your good results! Keep up the good work and keep us posted with your progress! SVR for all in the near future! Take care and best wishes!  Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Trenz on February 19, 2015, 02:40:00 pm
And so it begins...UPS dude just delivered Harvoni and Ribavirin. I'll start them this evening. 24 weeks to go. Doing 24 wks because relapsed a couple of months ago from Sovaldi, Riba, and Peg and have decompensated cirrhosis.
I'm geno 1A, diagnosed back in 1990, first treatment was in 2003,  Riba and Peg...stopped after 6 wks because it wasn't working and I wanted to die.
This 3rd time is going to be the charm!!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 19, 2015, 04:49:02 pm
Trentz, wishing you the "charm"! Best of luck!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on February 20, 2015, 07:01:28 pm
Hi,
Just finished 16 weeks riba/sol... 8 more to go. I have started to get cramps and tingling in me feet at night time just after I try and go to sleep, has anyone else had this?
Good luck to everyone out there.
cheers
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 20, 2015, 10:37:21 pm
Hi Franis60. I was thinking about you as I took the last of my 16th week today. Yep, we are down to 8!! I don't have any leg cramps, or any joint pains. I did before I started my treatment tho. I have more itching in the evening and I started having dreams! Good dreams! I can't remember dreaming like that for the longest time. Since dreaming occurs during the REM stage (deep sleep), I assume that means that I am sleeping better than I did for years.
Best wishes to all!
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Trenz on February 20, 2015, 10:47:24 pm
I just realized I posted to the wrong page. I just started Harvoni.  My bad, sorry for any confusion.  I have enough confusion for all of us!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 20, 2015, 11:04:06 pm
Don't matter Trentz, we all have the same thing! Our meds might be different, but we are all experiencing the same trials and tribulations that go along with this beast. Best of luck to you!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Trenz on February 20, 2015, 11:30:00 pm
You are so right CE, I hope we all get cured no matter what meds we are on!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on February 21, 2015, 12:42:54 am
Hi Chris,

Great to hear from you, I have been having a lot of joint pain and restless sleeping, but am hanging in their. 8 weeks and counting. We are all in this together Trent ! welcome.

cheers
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kimharvest on February 23, 2015, 04:06:32 pm
Lisa Marie: Good trick is to say or think, when I take these pills I will feel stronger and stronger. Embrace it as your savior. If you remain afraid and nervous about it you will feel more negative responses. I too am sensitive to drugs and usually go for half but this is a different ball game. Try not to think about it! Keep in touch.
My biggest point is nothing is worse than losing your mind from Hep C. As my mind clears, I feel a lot of sorrow over loss, all the aloneness, all the suffering in silence, all the guilt from feeling bad. I was totally losing the ability to take care of myself and was apathetic too. I lost interest in most everything I cared about. It was a lonely, sad, lost path to nowhere. If taking these meds will give you a new life of vibrancy and energy, you can only try. I am taking my one month blood test and am excited to see the viral count. It will be a week before my nurse practitioner appointment. I don't think I will ever meet this doctor. Thanks everyone for your advice and encouragement! Good Health!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on February 23, 2015, 05:22:04 pm
Kimharvest, 
Thank you, a thousand times thank you! I wish I were the strong one helping someone, courageous and encouraging, but sadly I'm not. Not when it comes to medicine,  or changes in my mind and body. I will do as you suggest and get positive, looking at how much clearer my mind will be, and how bright my future will be. 6 months is a small price to pay, I know. Fear grips me. I have some pain meds and xanax if needed. I won't take the Zoloft, scared of that too. But doc gave me the other for pain and anxiety. I take half at night, lol. Half of the lowest dose. Ugh. I better get with it, meds coming in tomorrow! Do you feel better?
Thanks again!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: amh on February 23, 2015, 07:31:09 pm
Hi everyone,
I finally started my treatment.  Just completed week 1 of 24 weeks of solvadi/ribavirin.  So far so good.  I know the side effects are cumulative so I am prepared (I hope) for some rough roads ahead, but I am taking this journey one day at a time so I am not going to worry about that.  Anyway, I am working full time and managing with at the moment minimal side effects.  Just happy I am one week closer to my goal.  Next week I have my first DR appointment since I started treatment. 
I enjoy reading everyone's posts, I will say I was one of those who was petrified to begin the meds.  I had my pills in my possession for over a month before I finally had the nerve to take that first set of pills.  But so far I'm ok.  This can be done.   

 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 23, 2015, 07:49:07 pm
Hi Amh, so glad you decided to start your journey! You'll see, as you finish each week, you are closer to your goal and it drives you to keep going strong! And once you get those wonderful words "undetected", you REALLY become determined to defeat the dragon! I am half way through my 17th week. So far things are going well. Everyone will have different affects, but the prize is the same. Good luck and keep us posted on your progress so we can cheer you on! Best wishes!
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on February 23, 2015, 07:52:38 pm
i was genotype 3 since early 80s. found out early 2000.s through exercise and diet ,there were moments i had a 0 viral load, then,  it came back, went up to millions. had rashes, itches, and always felt tired.i was treatment naive until i started riba and sov.if i  can do it, anyone can. just exercise, drink loads of water, rest, accept what comes . it goes away.keep your body and muscles in motion, if you can sweat, i think thats good too. get oxygen in your blood and water to wash away the dead virus.girls, this virus is gone from my body.i also had  the pills for weeks before i had the mental strength to start.i was svr 12 weeks ago, and no rashes, new energy, and a new addiction to zumba.. . go girls,!!2015 is your year!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 23, 2015, 08:06:13 pm
Zeena, you are a true inspiration! So happy for you! I look forward to the renewal of energy and health. I slowly became depressed, lost interest in things I loved to do, had weird randon rashes, hives, anxiety, panic attacks, hair loss, etc, never knowing that I had HCV. The puzzle pieces fit!  I pray that I see the SVR12 in July. Congrats to you Zeena on your new life! Take care!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: amh on February 23, 2015, 08:52:40 pm
Zeena & CE thanks so much for your words of encouragement.
 CE, every symptom you describe I have experienced.  Depression, lethargy, weird rashes on my feet.  My joints ached, especially my big toe, like I had gout.  Plus I always felt a bit separated from the world, like I carried around a huge secret and burden.  And it's still a secret, no one at work and very few people in my personal life have any idea that I am HepC+ and am undergoing treatment.
That is just on of the reasons I really love this forum, it is very reassuring to be around others who are going through the same thing your are.  Good luck to all of us!   :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on February 23, 2015, 09:29:36 pm
Yes, thanks to all of you! I haven't started yet, and meds due to be delivered tomorrow, I may wait until mid March to start as I have a lot going on at work, but those on this Forum are my inspiration. I'm not telling anyone  at work either.
I am finally kind of looking forward to starting because it will be the step toward freedom from this dragon. It is y'all words of truth that are helping me overcome my fears. I haven't been myself in a year, now I see it's probably the virus causing the changes. I am committed to being committed to myself for once. To exercise,  rest without guilt, work, and to be positive. 
Good Luck, God bless us all
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: debbie9947 on February 25, 2015, 11:28:56 am
I am starting the same treatment, waiting for it to come today via ups. It took awhile for insurance to approve and then get the co pay assist for the rest. My son found this forum and i am so thankful that you are all here. I am amazed at all the posts that talk about the having anxiety, feeling separated from the world, rashes,, that has been me... I never thought it could be connected with the Hep C. I had to start taking meds for anxiety and depression about 4 years ago, I didn't know what hit me. I was having panic attacks, but thought i was having a stroke and ended up at the ER many nights. I was clueless.
  I am grateful for this forum. I know I will need help through this and I want to be here for others also.  I have been getting things in order around the house before treatment started & took time off from work, I have been kind of dreading this day. Hopefully it wont be so bad. I haven't told anyone about the hep c or treatment starting accept my adult children. I wish i didn't feel shame and embarrassment about this.   Thank you all for being here.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 25, 2015, 12:46:18 pm
Hi Debbie and a great big welcome to you. I, like you, was amazed by this forum. It's a place where you can talk about your HCV symptoms and concerns, and actually have people who understand first hand what you are feeling. Only my immediate family know about my condition. We really have nothing to be ashamed of, but the general public really don't understand this enough to have compassion. I am about through my 17th week. I only experienced minor thing. In the beginning I did have a low grade fever and chills a few times. My biggest issue is the anemia from the riba and dry itchy skin. As for the anxiety and panic attacks, I started getting them back in 1981, 3 years after a blood transfusion! Who knew!! I was only diagnosed last year after my liver enzymes became elevated. Came as a real shock to me. However, I was fortunate to get on treatment and hope it is the only treatment I will need. I understand treatments have come a long way in the past few years with great outcomes. Good luck and God bless. Yes, I pray we all achieve SVR!
Best wishes, Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: debbie9947 on February 26, 2015, 10:35:46 pm
Thank you for your welcoming me.

Yahoo,, Your 17th week is about done. I am happy to hear that the side effects have been minimal for you. I started the treatment yesterday and hope all goes well..

 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on February 27, 2015, 06:33:06 am
Debbie and 17th week, I am reading your posts with interest and compassion. I got my Sovaldi and ribavirin yesterday.  I have not started. I knew I was waiting until either this weekend to start, or mid march, but now I have some slight cold and sinus symptoms coming on, so I know I won't start with any chance of weakening immune system. Good Luck to you Debbie on starting, I too am getting my house in order,  but have not taken off work. Please let us know how your first week goes. Also, does anyone take supplements? Are they helpful? Needed? I am thinking about taking calcium and  Vitamin D for bones and teeth. Also for pre menopause I take a natural herbal supplement daily, wonder if that would still be as effective?  I plan on calling the pharmacist, but thought I'd ask those of you guys and gals on treatment what your thoughts were. Also, if sleeping is a problem,  why wouldn't we be prescribed a sleep aid? Anxiety an anxiety med? Meaning is it not wise to consider taking those types of things and why.
Sorry to be a pill. I really need to succeed at this tx.
God Bless you and good luck Debbie and all!
LisaMarie
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on February 27, 2015, 12:07:56 pm
Hi LisaMarie, and welcome to you too! Hope you get over your sniffles soon and get on you battle of the beast! I, too, used to take supplements before treatment and my doctor said not to as they are hard on the liver. The coatings are what is not good. I don't take anything. I try to get my vitamins and good stuff from eating the right foods. As for any other problems, I would wait to see if they even will materialize first, and if they do, discuss it with your doctor and let him prescribe something if needed. Drink lots and lots of water! The best you can do for yourself on treatment. Helps to keep headaches at bay and keep you hydrated.
I wish you the best of luck as you go on your journey to SVR! God bless.
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: debbie9947 on February 28, 2015, 12:58:28 am
Hi Lisa Marie,

 I do not take any vitamins or supplements, I eat a variety of foods and hope I am getting what I need through the food. I also do not want to give me liver any more work. I need it to focus on ridding the virus.

I was on sleeping pills before starting this treatment,and only take when needed. I am sure if you develop ay trouble, your Doc should give you what you need.
I wish you luck,, Keep us posted :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on March 03, 2015, 12:31:29 pm
Hi all, hope you are doing great. I am just giving a brief update on my progress. I am halfway through week 18 of 24. I do feel different than when before I started. First the bad stuff: I still am anemic. My HGB is now 10.8, up .5 from my week 12 labs. I have some moderate itchiness mostly in the evening and mostly on my back. My skin is kind of dry, but I have been using a mix of vitamin E and baby lotion. Awesome!! I still have dark undereyes. The good news: virus is still undetected, liver functions are absolute normal. My mind is clearer, I feel like I have a bit more energy. One big, but strange thing I noticed is my lack of joint pain, and thickening of my thin hair! I always had joint pain before treatment. I have none, nadda! I have no headaches either. I only took a total of 2 Tylenol at 2 different times for a headache at the beginning of treatment. That's it! Maybe it's the large amount of water that I consume. As for my hair, before treatment, my hair was falling out over the years, and was so thinned out you could see my scalp on top and I had a receding hairline. My eyebrows almost did not exist! Now, my baldness filled in, I have fresh new growth at my temples! And my eyebrows are filling in. Did anyone else experience this? The doctor thinks my hair thinning had to do with the virus. You all can't imagine how ecstatic I am about this. I do look forward to getting my face color back again too. I look rather sallow. But I look more forward to achieving SVR after treatment! Well, that's it! I pray that we all get cured! Take care and God bless!
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on March 04, 2015, 04:03:45 am
Hi Chris,
Good to hear from you fellow dragon slayer. Also on week 18, great to hear about your hair;) I thought we were suppose to loose it! I think mine has got more grey over the last weeks but none has fallen out.
I have a bad shoulder and it has got worse over the last few weeks, amazing your aches are getting better. I drink a lot of water but very little at night time due to it keeping me awake . When do you take your Solvaldi pill? Do you drink much water at night time ?
I also have black under my eyes and look very pale....but nearly their!!
Keep in touch
cheers
Liam
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on March 04, 2015, 06:51:51 pm
So today they decided to bring the RBV back up to the full amount of 6 caps. They say my body has had time to adjust to the treatment and they aren't expecting the anemia to return. Hope it doesn't interfere with my sleep I've been sleeping soundly on 5 a day.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on March 04, 2015, 07:19:38 pm
Hi Liam! Slaying dragons is hard work! Lol! Hopefully your shoulder will get better soon. You must be swinging that sword too hard! Seriously tho, I do hope you feel better soon. I do drink water in the evening, but only Sunday thru Thursday since I get up for work at 4:15. I like to sleep till 6 on the weekends. I take my Sovaldi in the morning with 3 ribas. I am getting weary of gulping pills! I never took meds on a regular basis except for when I would have to take some antibiotics. I am looking forward to April! My doc made my EOT appointment for May 1. I pray everyday for us to achieve SVR. Take care fellow slayer! Best wishes, Chris

Hi Billy! Happy to hear your anemia is under control and you are sleeping better. Like I said, slaying dragons is hard work! Best wishes. Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kimharvest on March 07, 2015, 10:24:01 pm
One month viral load test came in undetected! 10,000,000 to none! People with 3a hold the hope! Sovaldi & Ribavirin can help us.

Warning: my nurse practitioner told me I was lucky I got in January; I hit a lucky bubble, they have now tightened up acceptances and are asking for more rigorous testing now.

I can't imagine refusing anyone this cure. I needed treatment 5 years ago. I know I could not have gone on 6 more months. I woke up in a strange house every day and was getting lost in my town of 30 years. They say the viral count isn't important but it slowed my brain to a stop. That and the exhaustion. I weep at times about the loss of the many years going into failure now that I can remember again. Hoping my mind gets even sharper after I am done with the meds. It is a whole new life for me. Good luck everyone! 4 1/2 more months to make sure it stays away! Can do!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: zeena on March 07, 2015, 11:10:40 pm
congratulations kim   it just keeps getting better!   svr 12 geno 3a
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on March 09, 2015, 06:03:17 pm
Congrats Kim, mine is now undetectable at 10 weeks also.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Danster on March 10, 2015, 09:48:07 am
Hello all…  I am geno 3a and was helped through support path for my Sovaldi. My girlfriend found a coupon online for Ribaviron (see one of my earlier post for info on that) which dramatically reduced the cost. I started my treatment Sunday. It is day 3 and the journey has began. I have not had any side effects at all. When I started my VL was 9+ Mil. I have no doubt that by the time I complete 24 weeks I will be cured. Up through Saturday when I finally got my fedex with the Sovaldi, I had been in such a mental knot…so much anxiety as I inched my way through the maze of my insurance company's denial for treatment, then the yellow brick road appeared which lead to support path. I am in sales… the stress has affected my work. Since Sunday I have felt a new freedom and since of renewed hope. I am grateful. I can already tell my body is healing. I felt it important that I share the hope.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: amh on March 13, 2015, 08:48:41 pm
Hello fellow dragon slayers.
I have almost completed a whole month of treatment, just 5 more months to go.  So far, so good.  Yes, I do get tired really tired at times. Yes, I do wake up with a bit of a headache but it goes away within a couple of hours. Yes, I am having difficulty sleeping.  My Dr. did prescribe Ambien but I take it sparingly.  But I am still working my normal crazy schedule, haven't missed a day yet.   To sum it up,  I am tolerating my treatment of 1,000 mg of Ribo and 400mg of Solvadi really well.  No complaints, especially if I achieve my goal of being HCV free.

To everyone out there afraid to take that first pill, just do it!  I was so scared to take that first step because I was afraid I would be really sick and unable to work, but I am doing it.  So can you.  Just follow everyone's advice, eat well, drink lots of water, rest when you need to and drink lots of water!   
To everyone who are currently in the middle of their treatment, especially CE, who started this thread, thank you, reading your posts are inspirational and encouraging. 
I just had blood work yesterday, so am keeping my fingers crossed I get some good results.   
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on March 13, 2015, 09:44:42 pm
Congrats, amh on your first month of slaying! You seem to be right on track. You will def get some good news on your lab report. Tomorrow starts my 20th week. When
I look back to the beginning of treatment, I had visions of horror, but it really went quite well. Of course there are some rough spots, but nothing like what I heard it used to be like years ago. Right now all my labs are excellent except for my HGB, but it has stayed above 10.3. My undereyes are quite dark, but yay for concealer!! Right now not only am I doing well at my job, but I am almost finished with painting my home and fixing things up. Despite the low HGB, my energy has increased! And my hair got healtier! Maybe that is from all the water and extra conditioning. Having this dragon has definitely forced me to change my lifestyle for the better. I also want to thank all my fellow slayers for your incredible friendship and comforting words. You are all wonderful! I pray each day for all of us to be finally cured.
Hugs to all! Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on March 14, 2015, 06:13:00 pm
Hi,
Just checking in, welcome amh, you will be undetected and good to hear you are managing ok. Yes the tiredness seems to be a recurring theme,I drink a lot of water and I am sure it has minimised the side effect.]
CE...great to hear from you, I start week 20 this friday;) Can so relate to the rings under the eyes, I seem to wear sunglasses every time I go out. I started doing Pilates and it is really helping with the joint pain. We are nearly their my friend,to all those who are starting the journey just like to say that it has been no where as bad as my head was telling me it would be.Its all manageable;)
Thankyou all for your support..."keep your eye on the prize"
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on March 22, 2015, 11:12:24 am
Its week 12 and everything has been going very well other than some irritability and occasional insomnia. I was pretty used to that already due to the condition of my liver, but now something else has popped up. I've developed very itchy rash that is sometimes associated with Ribavirin. Some are legions and some areas are bulls eye circles and its driving me up a wall. I'm afraid to mention this side effect to the VA because they might terminate the treatment so tomorrow I'll just ask to go back to 5 RBVs a day rather than the full 6....I'll just tell them that 6 is causing irritability and insomnia. I will tolerate this and just keep it secret rather than risking termination of the treatment.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on March 22, 2015, 01:44:48 pm
Billy,
I'm sorry you are having the rash. It's interesting because I haven't started tx, but have some bullseye red spots.... wondered what they were. Also, why would VA take you off tx? I would hope not.
And, to all, my start date is April 3. I think I'm ready...... I'm terrified though still. Sigh. Praying for you all, wishing the best. We will slay this dragon.
Warmly and Appreciatively :)
LisaMarie
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on March 22, 2015, 01:55:12 pm
Riba rash is a well known side effect which can be treated by dose reduction also helpful is OTC hydrocortisone cream   

Here is some info from the VA web site

http://www.hepatitis.va.gov/HEPATITIS/mobile/index.asp?page=/provider/reviews/treatment-side-effects&#S6X

Skin Rash

20-25% of patients develop a skin rash, which is generally due to ribavirin. It is a fine, red, petechial or reticular rash, and tends to be seen over the arms and trunk, although it may be present diffusely. It tends to improve and recur spontaneously during treatment.

Management

Topical therapies, starting with moisturizing lotions and then low-dose steroid creams (eg, 1% hydrocortisone or triamcinolone), are often very helpful in improving the rash and its associated pruritus.
Oral medications such as diphenhydramine may be helpful if topical therapies do not relieve symptoms.
In severe cases, dosage reduction or even discontinuation of ribavirin tends to be helpful, with reintroduction as symptoms improve.

Ps the little red spots are called petechia they can be a symptom of liver disease and also some people just have them. I have hundreds of them on my arms, chest, stomach, and back
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: tinybim669 on March 22, 2015, 01:59:47 pm
The Ribavirin gives me dry skin but never developed into a rash. I started using baby lotion ever couple days after my shower and I haven't had any problems since I started using the baby lotion
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on March 22, 2015, 05:09:47 pm
I'm not sure if they would stop the treatment over this or not...I'm just worried that they might. They are a Govt agency and they march to a different drum than private doctors.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on March 22, 2015, 05:33:59 pm
One would hope they would want to help make your treatment more tolerable by telling you about the hydrocortisone cream or the benadryle or maybe prescribing something or last resort reducing the riba.

That would be very unfortunate to be afraid to tell your doctors what they really do need to know so they can treat you properly. Riba rash is not a uncommon side effect so they really should not be concerned unless you want to quit because you cannot tolerate the sides.

Hope you try the cream or Benadryl and it works out for you

Good luck on treatment
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on March 22, 2015, 08:57:03 pm
I read that Almond oil is good for those dry patches.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on March 22, 2015, 09:13:08 pm
How is almond oil for very itchy rash?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on March 22, 2015, 10:09:43 pm
Too soften the rough scales that form.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on March 22, 2015, 10:23:27 pm
But does it help with the itchiness? Dry skin is one thing but a hives like rash that Ribavirin sometimes can cause can be very, very itchy.

But I guess as long as you feel better you can always escalate treatment as needed
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on March 24, 2015, 09:06:48 pm
I contacted the VA monday and told them about this rash and they said they won't terminate the treatment unless it gets worse, like boils or something. They reduced the RBV down to 1000 but they are concerned about the rash and want me to try and make it in before my my apt next Wed. I honestly don't know for sure if RBV is causing this - it could be some type of fungus like ringworm for all I know.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on March 24, 2015, 10:50:25 pm
About 25% of people treating with Riba develop the rash so it is a reasonable possibility it very well could be the riba glad you decided to be honest with your doctors and that they are trying to help.

I all of a sudden last week got a rash on the backs of both my hands and forearms I also never get rashes or skin problems so it kinda freaked me out.

Fortunately it did not itch and did settle down and go away after I used some hydrocortisone 1% cream I had in the house.

The rash can actually have serious adverse reactions for some but very few so I am sure you will be fine. Just maybe itchie for a while but I hope it clears up for you.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on March 24, 2015, 11:05:51 pm
ok thanks.
 
When I find out exactly the cause I will post it. It may or may not be RBV related and I didn't mean to worry anyone about their treatment.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on March 25, 2015, 06:23:49 am
No, I think we were more concerned about you and your rash issues, as well as the possibility the VA could stop tx. Glad you told them, and i suspect it's caused from tx, and the Dr's need to be aware of it, but I understand your concern and your need to be cautious in what you tell them. But, since this is a common side effect they need to know about it and help you with it so it DOESNT get infected like they said.
Keep us up to date please. Try not to worry! I'm doing enough worrying for all of us! ??? ???
LisaMarie
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on March 27, 2015, 05:28:12 pm
Just checking in..... Tomorrow starts week 22! Only 3 weeks to go! I want so terribly to be done with this battle. My sword is getting dull! Other than my dry skin and tiredness, I think I'm doing ok. My HGB is still quite low as it has been thru the whole treatment. I really notice it when going up stairs. My mind is quite clear though! And my past interests are reviving! I just hope the prize stays within my reach. Prayers for all for SVR.  Best wishes --Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on March 27, 2015, 10:40:40 pm
Chris,

Happy to hear you're almost through with tx!! I'm VERY hopeful when I hear you say you are getting a clear mind and past interests coming back. That is my hope and prayer for sure. I start friday the 3rd of April. Rain or shine, work in order or not, I have set my date. I have 2 months worth of meds staring at me, I put tx off for 3 family birthdays in March, one being my 50th on Thursday... also put off to get work in order, but I see it's just not realistic, so off I go, with an anxious but hopeful heart. I'm depressed, scared, mad. Hard to live with, hard to work with I'm sure. On the 3rd I will wake up, eat breakfast at home, which I never, ever do during the work week and take my first 3 pills. Then go to work, then head to hospital for my MRI, (my first ever, lol) to check my septated complicated liver cyst... praying it hasn't grown. Thanks for listening.
LisaMarie
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on March 27, 2015, 10:56:09 pm
That's great Chris! You're almost there. Wonderful to hear about clear mind. I would welcome that too!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on March 28, 2015, 02:39:01 pm
Thanks LisaMarie and Kim. When I first started treatment, I had the same fears that you did. I also was depressed, scared, and really mad that I was invaded with this virus. But stay strong, keep it in the back of your mind that you will win. I have not had a bout with depression or anxiety for months now! I really feel different. Drink lots of water. It really does help with headaches and keeping you hydrated. Best of all, if you do get any issues,you always have the wonderful people on this forum to answer your questions and give you unconditional support. Good luck to both of you.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Danster on April 01, 2015, 02:49:30 pm
Has anyone experienced sore gums and sores on the tongue from Sovaldi/Riba 24 wk regimen? I also have little "hotspots" on my body that are dry and itch badly behind my knee, ankle & waistline area. Can anyone suggest something for these symptoms?   
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on April 01, 2015, 07:30:21 pm
Just returned from the VA and showed them the rash. They said it could even possibly be the sofos rather than the RBV. Either way I made it clear I'm not going to stop treatment now that I'm half way home over some itchy little rash. They didn't offer anything for the condition other than reducing the RBV to 600 temporarily, and recommended over-the-counter hydrocortisone and Sarna Lotion (which I already had). Sarna works pretty good...the camphor in it has a cooling effect that helps a lot. Heat aggravates the itch in my case and I found that getting up at night and rubbing a frozen water bottle over the rash works better than anything if things get too intense.... and coconut oil helps soften the roughness.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on April 02, 2015, 07:35:04 am
Tomorrow I meet Sovaldi and Riba. I'm hoping I've just made this out to be worse than it actually is! I've mentally prepared for it all except work environment. Is it so wrong to work in a small office and not want to coworkers to know you're sick?? I work in medical field.
I have been going through stress at work. Huge work load. Worry, even got weepy for a couple days. My GI Nurse told me I should have been taking my Zoloft....... I started it then flushed it down the toilet so I wouldn't be tempted to take another. I was up all night, probably 10 times with diarrhea. I would rather suffer side effects from treating my HCV than from treating something that may not need to be treated. Or, I can treat other ways, exercise, music, etc. I have low dose xanax to take if I felt I needed it. So, my question is based on information from nurse, do any of you feel depression or extreme anger/ mood swings? I haven't seen any comments in here about this issue other than some irritability. I don't have depression and don't feel I should take antidepressants,  although I have NOT been myself for a few months now, my symptoms don't fit the criteria for depression. Opinions?
I AM concerned about work performance,  energy levels, etc, but don't need to add worries about mental health issues.
Thank you all for your support. Wish me luck. I've prayed for all of you many times.
LisaMarie
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on April 02, 2015, 07:39:59 am
Billy, so glad you went to VA and told them! I start tx tomorrow,  Friday the 3rd of April and based on what I read from y'all about rashes and skin itching I got myself some Melaleuca oil, lotion, hydrocortisone cream mix. I order melaleuca products monthly, it's an amazing oil so I will let you all know if it works! Hopefully I won't need it......
LisaMarie
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on April 02, 2015, 02:16:58 pm
Lisa, this treatment works very well in spite of a few uncomfortable side effects. I noticed an improvement right away and after 10 weeks you will begin to feel like the person you once knew. Everything gets better - your mood elevates, your outlook improves, your energy level heightens.... Its well worth any inconveniences you may encounter.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on April 02, 2015, 05:55:44 pm
LisaMarie, first of all I want to wish you the best of luck as you start your battle. As for the depression, anxiety, panic attacks and mood swings. I suffered with these for 30 years not realizing it was a symptom of HepC, which I didn't even know I had. Since starting treatment, I have had a few days of being irritable, but as of late, I have nothing! I feel completely relaxed, I am once again enjoying doing things that I had loved, but lost interest in over the years. My mind is clearer. I still am tired, only because my hemoglobin is so low from the riba. I had some mild itching and dry skin, but no rashes. Everyone will react to treatment differently, but to rid your body of this dragon is worth it! Good luck to you too, Billy as you are half way there! I got 2 more weeks. It was a long winter! Lol. I pray for all of us to achieve SVR! Best wishes.  --Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on April 03, 2015, 06:14:31 am
Thanks so much for replies. They were of great help/ hope for me! I've decided to hold off starting until Sat just in case I have 1st day side effects that will interfere with work. (When I planned my start date I didn't know we'd have patients today and short staffed.)  but, after reading your replies, I think I can work and now I'm even looking forward to starting. Didn't feel that glimmer if hope, just dread and duty. Thanks again, so much.
Lisa
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Greatful on April 06, 2015, 05:08:00 pm
Hello everyone, I just received my Solvaldi today (already had Ribovarin) and plan to start my treatment tomorrow. I've had this beast for 35 years and am so ready to beat this. I went through treatment in 1999 (interferon and ribovarin) only to relapse. The side effects from the treatment were so bad that I said I would never use interferon again.

Fast forward 15 years and we have Solvaldi. I have Express Scripts as prescription insurance, and got caught in the December/January we are not covering Solvaldi anymore debacle. Thankfully my doctor and the third party pharmacy that tried to get my insurance to cover the cost, also helps when they don't. They applied to Giliad and Merck programs and were able to get me both meds for free!! That's why I'm calling myself Greatful on this forum, because that is how I feel.

I'm so glad they have these forums now for people in treatment to share their stories. This opportunity means so much to me as it does to everyone on here. I look forward to sharing my experiences and cheering other on.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on April 06, 2015, 05:23:44 pm
Welcome Greatful! That's a fantastic name! We all can relate to it as we are all on that same boat. I started this string 22 weeks ago when I first started treatment. In that time, I found friends, answers, and the best support. I wish you all the best as you begin your battle. You will succeed this time! Blessings to you.  --Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Greatful on April 06, 2015, 05:33:06 pm
Thanks CE, your posts have been inspiring to me. I am working through treatment as you have. Last time the side effects were so bad, I had to quit my job, this time that is not an option. I feel confident I can soldier through this time, and reading your posts and those of the others in treatment here bolstered that feeling.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on April 06, 2015, 10:47:37 pm
I started tx Easter Sunday. It was time. So far so good. But every piece of advise and encouraging words I carry with me every day. I have only had headaches, some queasy stomach. Water is the key.
Good Luck and welcome greatful.
Liss
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on April 06, 2015, 11:20:10 pm
You are right about water. It sounded too easy to be true but it really does help.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Danster on April 11, 2015, 10:44:29 am
I have been reading through some of the post from all of you. I got lab results back from my 4 week check point. I am on Sovaldi/Ribaviron for 24 weeks with Genotype 3a. I was hoping I would be undetectable, but I went from +9 Mil VL down to less than 15. I am so suturated with all these drugs and my body definitley notices it in a big way. Some days are good, other days I lose energy at around 3:00 and my day is done. One member suggested SARNA lotion for the itching and slight rash. This is a wonder lotion. (at least it seriously helps me) It is steroid-free with 0.5% Camphor & 0.5% Menthol. I strongly suggest anyone having problems with itching give this a try.

I am wondering if anyone can tell me if my test results are on-track?  I've heard of some people that are UD after 4 weeks.  <15 is impressive and is a huge boost to my moral… I HAVE to beat this beast!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on April 11, 2015, 11:12:55 am
Danster,

Sounds like meds are doing what they are supposed to do! Killing the virus. Without tx virus is replicating, with numbers getting higher! Your numbers getting lower! Virus losing ground in your body! Meds are winning the battle!
I am on day 6....... it sucks, I hate it, I am still working on my attitude. On a positive  note I am doing very well, water solving most of my side effects. First labs showing the effects of meds on RBCs, etc, my Basophils are high, and oddly rbcs, hgbs, are all abnormal high, not low..... but I have a question  for you, do you have cirrhosis? I just wonder if that makes it tougher on body, feeling side effects more.
Oh, and i use Melaleuca oil compound with cortisone. It works too.
Did you feel side effects right away?
Thank you for your input. I just said a prayer for you. That you will be free from virus on next check up!
LisaMarie
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on April 11, 2015, 11:48:08 pm
Hi Danster,
You're lab results are terrific! At 4 weeks, I still had a viral load of 63. I went UD somewhere between 4 and 8 weeks. And my viral load was only 950,000 to start. So I think you are well on your way to UD and beating this beast! I have started my 24th week. My side effects have been mild except for my hemoglobin being very low the whole time. I have really felt it the last few weeks with fatigue and getting winded with stairs. So glad to be done next week. Best of luck to you and Lisa. Stay strong and keep your eye on the prize! You will be rid of the beast for good!
Best wishes -- Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on April 12, 2015, 09:44:17 am
Chris, week 24!! You are entitled to a do a happy dance right now! (I can't wait to be on the last week.) I have one down, and yesterday was stuck out of town with no meds. I made it home around 11 pm, took ribavirin,  but felt off schedule, wondered if I would have a long night, but all was fine. The ribavirin  gives me headaches. Water cures them, along with a 200 MG ibuprofen once in awhile. Best advice ever is water and support system.
If you can, could you give us an update after you're done with week 24?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on April 12, 2015, 09:45:00 am
Chris, week 24!! You are entitled to a do a happy dance right now! (I can't wait to be on the last week.) I have one down, and yesterday was stuck out of town with no meds. I made it home around 11 pm, took ribavirin,  but felt off schedule, wondered if I would have a long night, but all was fine. The ribavirin  gives me headaches. Water cures them, along with a 200 MG ibuprofen once in awhile. Best advice ever is water and support system.
If you can, could you give us an update after you're done with week 24?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on April 12, 2015, 10:50:38 am
LisaMarie, I always carried a one day supply of pills with me for whenever I could not be home to take them. I always take my pills at 6 am and 6 pm. Worked very well for me, never missed a dose. You never know when you may be delayed on the road or for whatever reason, but you will have your pills. My "on the road" back up will be the last dose I take. AMEN!! I AM so ecstatic about it, but the waiting game will probably be nerve racking! I will update with the news. Praying for SVR. Take care. --Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Danster on April 12, 2015, 11:04:27 am
Hi LisaMarie,

I appreciate your reply. First of all, no, I did not feel side effects right away. Initially I felt like I got clarity of thought. Perhaps that was just because mentally I knew I had begun my journey with treatment after a couple decades of being infected with this disease. Secondly, I did not have much liver damage. My fibrosure score was at level 2 which is why my insurance company denied coverage. I was fortunate and extremely grateful that I was accepted by support path for free meds. I have days (daze) where I am completely exhausted and others that I zoom right through as if I were normal. The down days are very noticeable. I manage the advertising for a magazine so I always have 12 plates spinning on 8 sticks. Kind of hard to work sometimes, but the show must go on and I am on a mission to beat this thing.  Thank you for your prayers. I return that to YOU and everyone else that shares what we are going through. There really is strength and comfort as we trudge the road to happy destiny!
Best of luck to you…


Danster
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Danster on April 12, 2015, 11:23:01 am
Chis,

I am very excited for you! Today I start week 7. I don't like to count the days, weeks or months… but it is hard not to. Doing it in weeks is an easier chunk of time to manage. LOL. To hear that my VL at <15 is a great number after 4 weeks is more than motivating. I needed to hear that from someone. I don't go back to my GI doctor until April 30th. At that time I am sure they will also confirm my progress is very good. For a 62 year old guy, my skin has always been pretty good, despite a little wear and tear. There has been a BIG difference in the texture of my skin in the last few weeks. I am wondering if you experienced that as well? Will it come back? I am a strong advocate of takiing care of myself… (not so years ago which is why I have Hep C in the first place) For now I am using lots of lotions & oils. The SARNA works very well for the itching. I will also follow your advice regarding carrying a daily medication dose with me. I might be reluctant to do this during summer. I live in an area with extreme heat during the summer months. I travel (in my car) every weekday to meet with clients - from one to the next. Not sure if the heat would affect the medication. Your thoughts?

Again, thank you for your feed back. Please let us know your results after 90 days. Prayers and light your way!

Danster
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on April 12, 2015, 11:40:34 am
I missed a dose early in the treatment once so I had to mark two containers - Morning - and After 5. This treatment effects people in different ways, if I had genotype 1a I would have shot through the treatment without a problem...I felt unbelievably good and wondered what all the fuss about side effects was about.  It wasn't until week 8 that I noticed an itchy rash and by week 10 it had gone ballistic. Makes me wonder if this treatment were not made especially for 1a and not for the 24 weeks required for 3a. The VA reduced the RBV down to 800 mg - 2 in the morning and 2 in the evening. Most of the rash and itching went away, but I worry what effect that will have on the final outcome.  Maybe in the final month I'll go back to 1200mg,. My viral was still 57 at week 6 but was undetectable at 8. Insomnia is still an issue.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on April 12, 2015, 01:46:22 pm
Danster,
I would still take a daily dose with you every day. Don't leave it in the car, tho. Do you carry a wallet? You could put at least a Solvadi and 3 Ribaviron in a small plastic baggy and fit it into a pocket of your wallet. There were quite a few times that I was not going to be home in time such as when I would go shopping after work. I think it is pertinent to keep on time with the meds. As for my skin, I always had nice skin too. I will be 62 this year. A few weeks into treatment it got dry to the point that I was slathering my face with moisturizer like crazy. I never got any rashes, but did have a low grade fever and chills in the beginning. Also, my eyes are very dark underneath like I didn't sleep for a week. I do hope that clears up. I am sure it will take time till these meds clear out of my system. Keep posting here of your progress. Blessings to all! -- Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Lynn K on April 12, 2015, 07:34:51 pm
I have a little pill container if I am our and about running errands. I have seen a metal UND you can attach to your keys.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on April 13, 2015, 07:04:41 am
Yes,  I plan on carrying a dose with me. We were at an out of town event, and all I could think of was my evening dose of meds. Since I just finished my first week I guess I'm still in the figuring out what works best phase. Won't happen again though!.
And I've had nausea since that late night dose.... Ginger tea is what I'm trying now. Gotta get through hectic days at work 5 days a week. I also feel like a vice grip is around my liver...anyone else experience  this? It passes but comes on slowly and leaves gradually as well. It doesn't bother me because it's the only side effect that makes me think of an army in there fighting a battle and winning! Another question for y'all, my stools are light, not white as in a dysfunctional liver, but kinda close. I will talk to my Doc about it at next visit, but wonder if it's the meds? At this point I can feel, on week 2, nausea and have had the headaches since day 1. Only nausea seems to be "unfixable"..... sigh..... but if this is as bad as it gets I will survive the next weeks. I do take it in weeks. Trying to change it to months. they sure passed by quickly before I started treatment lol!  I also need to consider that I have a complex cyst on my liver will get results soon and that may have an effect on my body as well. hope I'm not sounding negative because I want to be helpful and not bring people down and I know that I read every word the others are sharing and want to share Hope not dicouragement ! I was so fearful, don't want others to feel that. This is doable! One week at a time.
thanks everyone for sharing. Chris, you are awesome. Danster, thanks so much for responding. Billy too! Remember  I'm just starting and appreciate y'alls input and support!
Have a great week.
Lisa
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on April 13, 2015, 12:19:48 pm
I just read an article that says that itching and rashes can be caused by an overloaded body eliminating toxins through the skin....that's why its so important to drink lots of water to help flush the toxins so it doesn't have to resort to an alternate method.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on April 13, 2015, 01:59:59 pm
Billy,
Makes .sense, and well normally I can't drink a lot of water I took everyones advice and prepared myself and just drink lots and lots of water and it's not difficult it's as if my body needs it it's the Ribavirin  that seems to require it. if I even think I'm getting a headache most of the time the water seems to heal it I just drink and drink and carry water with me everywhere.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on April 13, 2015, 02:29:18 pm
Billy, that really makes sense! I drank so much water over the past 6 months it's a wonder I didn't grow a hump! Lol! But I only had 2 headaches and no rash the whole time! Great advice for all!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Greatful on April 13, 2015, 08:01:38 pm
Hey Everyone,

Week one complete and I'm feeling good. This is definitely easier then the interferon. Lisa Marie, I too have had some odd sensations from my liver. The gripping you talked about and some aches. I'm sure it's the meds fighting for us, I urge them on.

Besides the water, I also use yoga and oil pulling to feel better. Yoga helps with any aches and pains while oil pulling helps to eliminate toxins. Google oil pulling, it's just swishing oil in your mouth for 20 minutes a day.

Like some of you have said, I feel like I have really good energy sometimes, then all the sudden I'll be really tired. I'm just grateful for this treatment and feel really positive and I make it through while working. I'm taking it one week at a time as far as a countdown, but really day by day.

Thanks to everyone on the forum, it's such a positive place and feel safe sharing.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on April 16, 2015, 01:57:13 pm
Ok my fellow SVR users. BAD day. I'm sorry, helpful hint to self: NO JUNK FOOD, SMALLER MEALS. I am so tore up. Stomach. Brain. Tired. Wanna cry my eyes out. 2 days in a row I slacked on my healthy eating..... say a prayer for me!
Thank you
Lisa
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on April 16, 2015, 04:12:37 pm
Prayers for you LisaMarie. Give yourself time to adjust. You will find what works for you. This treatment is no piece of cake by any means. Praying for you to feel better. Take care.
-- Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Greatful on April 16, 2015, 06:23:59 pm
Lisa Marie, I feel for you. I experienced some of the same thing this week as far as the not eating well and feeling bad. I know you said you had a stressful job, so that's just adding more to the mix. I'm starting the feel the saturation of the meds in my body, it's that feeling you get on heavy antibiotics sometimes if you know what I mean.
Hep C has been making me feel sick for years, panic attacks, fatigue, anxiety, depression. I am in a lower paying but not stressful job because of Hep C, which now is a good thing. I can sit in my tiny office and drink water and go to the bathroom all day virtually unnoticed.
I agree with Chris, I think we will adjust and figure what we can and can't do while on treatment. Anyway, I hope you feel better soon.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on April 17, 2015, 01:49:25 pm
Thank y'all. I pulled out if it, only to get hit so hard with severe and pain and pressure that lasted about 45 minutes to an hour. We reluctantly decided to go to ER, but I left after thankfully pulling out of it. But. Today, still feel the bloating (lower abdominal distention) , very strange,so all I can do is attribute it to the meds, and keep making my way through until I figure out what works. What happened last night was awful. Unrelenting pain, pressure, slight nausea, after all day of slight epigastric pain. It just made its way down and turned into that! I got very sweaty ( I work out regularly, don't sweat, and don't throw up), thus the ER visit, because we just didn't know what else to do.
Mercy came, I slept very well, weekly labs ok, but still no liver cyst results.
Thanks for listening. I'm sharing to help, not to hog, and sharing to get input from anyone.
Thanks a hundred times over for prayers!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on April 17, 2015, 07:19:35 pm
So happy to announce, I AM DONE!! Completed my 24 weeks! I cannot wait to not take pills tomorrow! Now I will join the waiting gang. This will be tough too. I hope and pray this treatment has done it's job. I will post my results in 12 weeks. Fingers and toes crossed, and lots of prayers that I achieve SVR. Good luck to all that are still battling and those just starting. I continue to pray for you all. Thanks to all my dragon fighting friends for the kind words, strong support, and excellent advice. Best wishes and hugs to all! Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Greatful on April 17, 2015, 08:07:03 pm
Congratulations Chris! That must feel so great. Wishing you SVR!!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on April 17, 2015, 09:07:05 pm
Good luck, thanks for the water advice, most of my itchy rash is gone.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on April 17, 2015, 09:21:01 pm
Congratulations Chris, !!
I finished yesterday, I enjoyed binning my " pill counter"..... It's been a privilege to share this journey with you. Now the waiting game begins. Do they tell you your 4 week results as well? I have to wait until after the 12 weeks.
All the best my friend, we have a new life.
Cheers
Liam
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on April 17, 2015, 10:06:15 pm
Hi dear Liam, it certainly has been a privilege to share our journey but more if a privilege to make a friend. I see my doctor May 1st. I have no idea what my next steps will be at this point. I can't wait to start feeling that incredible vitality that the "cured" speak of. I wonder how long it will take. Well, I hope to hear from you on the "other" side of the forum! Take care and happy new life to you! On to SVR !!! 
Best wishes.  -- Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: tinybim669 on April 18, 2015, 01:25:38 pm
Congrats Chris hope you the best.
I just got my 12 week results back and hep c was Undetected. Yay.... another 12 weeks of pills to go. Good luck to everyone.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on April 20, 2015, 06:24:55 pm
800 mg of rbv and 3 liters of water a day has the rash all but gone. However,  sleeplessness and brain fog are worse. Last friday I finished a job at 6:30, got paid and lost a 600 dollar check before I could get to the bank on Sat. They put a stop pyment on the check and wrote a new one but I felt like a fool. Today I took a 50 dollar bill to work... it was all gone when I got home and I can't account for 1 cent. I read that RBV can cause those effects.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Michigan on April 20, 2015, 10:15:22 pm
I am a 42 yr old female with type 3. First day of 24 week Solvadi, ribasphere treatment. I work full time and have a teenage son. SO thankful to find this forum and to be on treatment. Looking forward to get this out of me! My doctor is great and got me on treatment right away, although I've had hep C for 10 years. Just recently went for help. Only close family know of my hepatitis, hoping to survive busy summer months at work without any issues. Nervous, scared, but thankful for treatment.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Greatful on April 21, 2015, 08:45:06 pm
Hi Michigan, welcome to the forum. There is so much information here, it's great. I'm just two weeks into treatment and would say I have light side effects so far, working full time, so far so good You will make it through treatment and beat the beast.

Billy, I think you are so right about drinking the right amount and more of water. I woke up this morning with a rash starting around my wrist, down to one finger. I had not drank as much as I should for a couple of days and I'm pretty sure that was the issue. I put some Cortaid on it and drank more than enough water today. I can hardly see it now, but sure it was the water. Drink more than than your body weight requirement to keep some of side-effects at bay. I have insomnia anyway and take sleeping pills, the meds are making it worse. I have dealt with this for years, so I'm trying not to let it get to me. Every woman of a certain age has experienced brain fog, so again, nothing new. You will make it through this Billy, there is an end date to the treatment.
Stay strong and have a great rest of the week everyone!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on April 21, 2015, 09:46:58 pm
On the bright side I'm almost down to my last 8 weeks!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on April 22, 2015, 10:32:09 pm
Yes they do that sometimes, I had one make a perfect ring around my ankle like a bracelet, then shoot straight down to one toe. Pretty weird.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: hepc on April 26, 2015, 06:58:44 pm
hi all, Been lurking on the forum for a few weeks,

31 year old male, starting sovaldi ribi tommorow. Very scared that i will have a bad reaction to these drugs, been putting it off for a month now. This forum is very inspiring. I have gilberts so my billi is high. ast is 167 alt is 107. stage 3 genotype 3. Need all the prayers. Thanks to ce for starting this thread and good luck with svr.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: hepc on April 26, 2015, 07:00:06 pm
Forgot to post that billi is high 1.9 becuase of gilberts. And also lumps is hig hat 3.7 and one else had high lymps(absolute)very worried about that. thanks!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on April 26, 2015, 07:40:49 pm
Welcome, hepc, and good luck to you. You will be fine. You may experience some uncomfortable sides (everyone is different), but it is is nothing compared to what the beast does to your body. Stay strong, stay focused, and stay with this forum. The support here is awesome and I personally really relied on the friendship and knowledge here.  We all share the same same common factor and will all beat this at some point. I pray for all everyday to be healed. Best wishes to you as you start your journey. Take care.   --Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on May 04, 2015, 08:37:56 am
Hi Hep c, hope I can encourage you by saying I was scared also. Hate meds, just read my past posts, and my recommendation is that you get everything in place, good support system, communicate your needs to those around you, and get started. Chris is right, Hepatitis is the destroyer, the meds are the warriors ready and able to fight for your health! I'm on week 6. My first viral load results just came back and virus is UNDETECTED! I'm ecstatic! Amazed! Empowered! I was at 1 million 5 weeks ago...
As for side effects, again, read past posts, drink water!! For me I am able to work. I am fine. Side effects minimal and inconsistent, not debilitating. If you even feel a headache coming on get to that water! Take a Tylenol or iboprofen. Eat small meals, no fast food. All I can say is it's not as bad as you think and fight to win. God bless, and i just prayed for you.
Lisa
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on May 04, 2015, 08:58:43 am
Amazing how fast it KOs that viral load. I agree, its well worth the side effects.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kimharvest on May 04, 2015, 09:42:28 pm
Congratulations LisaMarie! You are doing great! You have come so far! I am so proud  watching you overcome your fears.  I am finding the 4th month to be the hardest but only because it wears you down. Also a bit anemic, so suffering from fatigue and uncontrollable constant riba rage.  Odd belly problems too like jello-belly.  Keep up the great habits and let us all pray this cure is forever for us 3a types. 
   Hang in there Billy!
   Welcome Michigan!
   Chris and Francis60 - All my best to you two! Please let us know your post treatment results please when they come in!!!
   hepc - welcome for joining the secret backbone we all can use.
Title: Genotype 3, Kicked Out for Riba Rage!
Post by: kimharvest on May 08, 2015, 11:38:16 pm
Just got kicked off!  I am half way through my treatment and I met with my nurse-practitioner and mentioned it was a tough month. I said week 13 and 14 were my roughest, but I was doing better but showing wear. My personality has become one of totally annoying and rude. But I was hanging on, trying my best. He decided I could no longer tolerate the anxiety and stopped my treatment. I begged him to let me continue, if it is ever too much I will admit it, but I am hanging in there. He wouldn't change his mind. It feels like I am watching my own murder. It also seems that if you ever try to mention any side effects you get let go. I have never had the chance to list any side effects. Odd. Do these doctors get paid a lump sum whether the patient follows through or not, taking the incentive for them to complete the treatment? I have 10 days to solve this.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on May 08, 2015, 11:49:43 pm
He wouldn't even try to adjust the dosage? What kind of jerk is he?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Greatful on May 09, 2015, 10:37:38 am
Kimharvest - that is the most ridiculous thing I have ever heard! You are having anxiety, a known side effect. Your doctor should help you by giving you an anti-anxiety med. I know, I had to go on them back in 1999 with interferon and ribovarian. If none of your doctors will help you with this, try meditation or yoga and tell your jerk doctor that it's working. Tell the jerk that you realize it's just anxiety and you are dealing with it. Say whatever you need to so you are allowed to stay on the meds. I am so sorry you have to deal with such a heartless doctor.

I got my first month labs drawn on Tuesday, have an appointment with the dr on Monday. Anxious for the VL numbers. My initial VL was 4.8 mil. I'll post my results as soon as I get them.

Welcome HepC, I like the majority of folks have not had any side effects that keep me from working or operating normally. Overly tired in the evening sometimes, no big deal. You can do this!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: hepc on May 09, 2015, 11:17:56 am
Kim Dont let him do that to you, you worked so hard to get to the 4th month, Be nice and say you just had some temporary anxiety. I am at my two month mark and doing well except for maybe slight dry throat? sore throat, but i dont want to tell my doctor its just really hot so thats why probably. Anyone else had this?god help us all, prayers for everyone going through this treatment.hepc
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on May 09, 2015, 02:59:47 pm
@Kim, you need to report this to a patient advocate. OF COURSE there are going to be side affects. There were people that had worse ones than you and their doctor didn't stop such a life saving procedure. I was rude at times too during treatment. Big deal! They'll get over it. Please report this to your insurance company too. They already paid for the treatment!
@ hepc, I had a dry throat and cough during treatment too. It got so dry sometimes, my eyes would water. My eyes also got dried out.
Good luck to you both. Kim, I pray you get back on treatment asap.
Take care.  -Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Greatful on May 11, 2015, 05:20:49 pm
Great news to share, from 4.8 mil to undetected in 4 weeks! Some slight anemia, but just something to monitor monthly at this point. This medication works everyone, keep up the good fight.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on May 11, 2015, 05:51:52 pm
Congrats, Greatful!!! That is fantastic news! My HGB was between 10.3 and 11 for my whole treatment. Just take it easy, you will get winded easily especially with steps. But you will be fine!! Best wishes to you!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on May 20, 2015, 07:21:57 am
Hi everyone, I've been out of pocket, for some reason stopped getting email notifications showing replies or comments from y'all. .... idk how to "fix" it.... anyway, wanted to check in and get back on track. I'm on week 8 or 9 I think. I stopped paying attention. I know that's probly' weird, but it's helpful for me. I know my end date, and that's what I'm shooting for.
GOOD, GREAT NEWS: VIRUS UNDETECTED AT WEEK 5!!!! Joy!!
But, as my precious Nurses told me of course I must continue on because the virus hides in organs and tissue and we want to kill it all. But, wow, what a boost to go from a million to zero in 5 weeks! I am an f4, no cirrhosis and treatment naive, but this week the irritability is off the charts. I am feeling quite rude and have decided to carry my xanax to work today just in case. I work with patients and of course co workers who only know I'm different, on some sort of meds for something.... thank God I have wonderful co workers. My family loves me and understands. I made my roommates  5 year old cry yesterday though with my irritability. NOT good! So, since this is the worst it's been with this side effect I made my apologies this morning, cried, made my plan of attack, and got back on this forum. Yesterday I also asked for a few days off next month. Also want to share with new treatment users something I've noticed and that is that with me the side effects are not consistent. Good days and bad days. No certain progression. It's a headache day, or nausea day, then 3 days of, wow, I feel "normal".... I just keep aware and have solutions in place for whatever is going on. The irritability freaks me out though. I strive for peace, balance, respect to all, so I pray this doesn't get worse.  ::) my tinnitus is bad, headache bad, but drinking water and ibuprofen solves it usually.
I think I'm all over the place in this post, so forgive me for that, I have a lot to say!
Oh and my medical bills, labs and MRI's for complex liver cyst are drowning me..... and I have great insurance, do I have not done labs in 2 weeks. I'm tired and crazy. Wonder if, even though hgb labs have been acceptable, if I'm not getting anemic? I was going weekly at first. Counts were out of range, whites up, reds down, but Dr said it was acceptable.
Time to check again?
Be blessed, I'll close now.
Lisa Marie


Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: hepc on May 21, 2015, 08:58:40 pm
Hi Guys, Great news. 2 week test results came back <15 iu/ml rna detected. Feeling good about the #'s. Billi is a bit high at 3 but doc said i prolly have gilberts. I go in for my one month in about 5 days will update you guys. prayers and healing to all.hepc
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on May 28, 2015, 06:51:00 am
Hep c,
Great news! I'm anxious for my next labs. They'll be drawn at 13 weeks. At 5 weeks I was already undetected. I was so grateful for the meds. At this point I am doing well, but have been experiencing slight but constant nausea. Nothing serious, but I find it puzzling because I didn't have it until now, 10 weeks in. Also wonder if any of you experience an aching in your muscles? Again, nothing debilitating but it's a new issue and is every evening when I lay down I notice it. Just a dull ache, especially in legs, calves, thigh muscles are most noticeable. I wake up nauseaus too.
One more question, if virus is being destroyed, shouldn't I feel better?
Thanks.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on May 28, 2015, 06:51:38 am
Hep c,
Great news! I'm anxious for my next labs. They'll be drawn at 13 weeks. At 5 weeks I was already undetected. I was so grateful for the meds. At this point I am doing well, but have been experiencing slight but constant nausea. Nothing serious, but I find it puzzling because I didn't have it until now, 10 weeks in. Also wonder if any of you experience an aching in your muscles? Again, nothing debilitating but it's a new issue and is every evening when I lay down I notice it. Just a dull ache, especially in legs, calves, thigh muscles are most noticeable. I wake up nauseaus too.
One more question, if virus is being destroyed, shouldn't I feel better?
Thanks.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on May 28, 2015, 12:18:56 pm
Also wonder if any of you experience an aching in your muscles? Again, nothing debilitating but it's a new issue and is every evening when I lay down I notice it. Just a dull ache, especially in legs, calves, thigh muscles are most noticeable.

Hi Lisa Marie. I am on Week 4 of 12 weeks of Harvoni+Riba. So it is similar to what you are on. For a couple of days I was experiencing cramps in foot and calf muscles - almost constant in foot arch. I increased my dietary sources of magnesium and potassium (dark leafy greens, bananas, pumpkin seeds brazil nuts, brown rice) and the problem resolved immediately. It may not help your muscle aches. But magnesium and potassium deficiency are often involved in muscle dysfunction. And the more water we drink (which most of us on treatment are doing a lot of) the more potassium we wash out of our body.

All the best to you! :)
kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on May 28, 2015, 04:46:29 pm
Hi LisaMarie! Great news to hear you are undetected! You are about half way done! As you get further into treatment, the ribavirin saturates your blood and not only attacks the virus, but your whole body! It is a very toxic drug. I ate a banana every day, and lots of green leafy veggies. This helps with the potassium and magnesium loss, which would cause muscle cramps and pain. Like what Kim said, we are drinking lots of water to counter the dehydration, and in turn we are washing those important minerals from our body. I am 6 weeks EOT and still eat that banana and the veggies along with lots of water! I developed a healthy habit because of treatment! The skin on my face actually became very dry and crepey. But within weeks after EOT, it returned to normal. I am 6 weeks EOT and feeling better. Not quite 100%, but getting there. I go for my 12 week labs in July. I try not to think about it cause it makes me nervous. I wish you the best as you finish the second half of treatment. A big SVR will make all those discomforts worth it! Good luck and God bless!   
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CureSeeker on May 30, 2015, 04:50:38 pm
Hi everyone!  *waves*

My name is CureSeeker, and I am HCV positive.

Im lucky I guess.  Stopped drinking pretty much by the time I was old enough to legally do it  Despite a high VL, and living infected since at least 1993, my LFTs are good and there is no sign of fibrosis. 

I started treatment yesterday.  I felt strange, but that could be psychological I suppose.  Had some tension in my TMJs and shoulders about and hour or so after my first dose, about 4:30PM I crashed and needed to nap for a couple hours, but nothing to really complain about.  Today is much better.

Thanks to those that advised me to eat with the Riba in the other forum.  Ive stocked up on fruit and whenever I start feeling sleepy I go grab a few pieces.  It helps alot with perking me up and the dry mouth.

Congratz to those that have completed treatment!  I cant wait to join you!  :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Justcass on June 08, 2015, 12:47:53 pm
You all are really giving me inspiration. I am geno type 3 as well. And should be on the meds in a couple of weeks. I just received the Solvaldi and waiting on the ribavirin now. Thank you all for your stories and I am looking forward to having you all to lean on through this 6 month journey! ;D ;D ;D ;D
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: notnow on June 08, 2015, 03:56:11 pm
Hi, I'm new on the forum but so grateful I found this site. I am in week 4 of treatment ribi+sovaldi for geno 2b...I have only 12 weeks of treatment but side effects kicked my butt this week, been pushing myself way to hard not realizing how stronng this stuff is. Bad headaches dizziness fatigue pounding heart emotional cried for two days straight could barely get out of bed. I am a single parent and work fulltime.....this confusion and fatigue is killing me...doc might lower my ribi depending on latest bwork find out tomorrow......I am so scared I havent told many people I have it and I just want to get thru this w/o alienating my friends and family or losing my job.....very happy to hear im not alone and that others are pushing thru this tough task
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on June 08, 2015, 04:26:42 pm
Welcome Justcass and Notnow! You will find many friends here, all in different stages of treatment, each having their own unique symptoms, but all with the same virus in common. I am 7 1/2 weeks post treatment now, and hope to hear the word cured in the near future. I had good days and bad. It does get better. Notnow, drink lots of water. At least 8 glasses per day. It REALLY does help with the headaches and dizziness. Eat plenty of green leafy veggies too. You both will find ways to help your symptoms. I worked full time also, but managed ok, and I never told anyone other than my immediate family about the HepC. I work in a hospital, but went to another hospital for my labs. Take one day at a time, you don't need to explain yourself to anyone. Use this forum frequently for your questions, advice, and support. Good luck to you both! May your journey go quickly and reach SVR!! God bless! 
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on June 08, 2015, 07:09:28 pm
Day 8 of Riba and sov for 24 weeks. Working a lot of hours. Fatigue and poor appetite. Itchy with just a little rash. Headache post meds that lightens up by hour 3. Had some heart flutter today with low bp before work. I tried to drink liquids all day and did a shake for meals. I just wasnt hungry.
Concentration is tough. Did 8 1/2 hours of work and went home and finished up what I could do remote from the computer.
Got out and repotted 4 plants into 5 gallon pots. In this heat it was a bit of a chore. I did a few and came in to cool down then went back out.
I miss the sunshine :(. Have sunblock to put on but getting a liitle sun 20-30 min a day.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: hepc on June 08, 2015, 07:43:36 pm
Hi All, 4 weeks no HCA detected! YAY!! Just wanted to update and let everyone know this med really is awsome and it works, keep going even when its tough. I pray for us all that we heal and move on with our lives.  One thing i noticed was that my LYMPHS Absolute were high like 4.2, anyone else had that during treatment or before?just curios. Good luck all. will update with 8 week results. thanks!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: notnow on June 08, 2015, 11:46:51 pm
Thanks CE I hope and pray u hear those words cured of hep soon my friend. Im praying my viral load was undetected,  I hear from my doc tomorrow,  worried about my side effects, the highs and lows are terrible, anyone who manages to make it thru this deserves to be cured, I have to force myself to take the meds especially the second dose, things get worse at the end of the day for me, mymemory is sooooooo shot and I get upset I cant remember anything.How can I be so tired and my heart is pounding away....god help me complete this treatment and be cured without going completely crazy
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TXLastTime on June 21, 2015, 06:51:24 pm
Hi everyone,

I am new to the forum and want to my post my experience and it will be helpful for a support system.

A little about me is I have Genotype 3 for the last 27 years. I got it when I was 18 and am now 45yrs old. I have stage 2 fibrosis and drink very rarely and do not use drugs. I imagine that's why I am still alive. As genotype 3 is very aggressive and can kill you fast if you have a drinking problem. I went through Interferon/Ribo treatment about 3 years ago and had a undetectable viral load at week 4. At 5 months into my 6 month treatment I experienced a very bad rash from the Ribo and had to get a steroid shot. I quit treatment 3 weeks early from my 6 months as I was miserable and wasn't getting the support from my doctor I needed. I would soon regret is as 6 months later the virus came back. The doctor said it could of been because I had fatty liver. I ate a lot of sugary foods before and gained around 25lbs during treatment.

Now I am into day 5 of the Sovaldi/Ribo for my new treatment. I have to take this for 6 months again. But, with no interferon its way more manageable. I am already feeling stronger as before I was very fatigued and needed two naps a day just to function. I dropped a bunch of weight before treatment and now know how to control my weight.

I will post blood work results in a few weeks to show my progress. I can't wait to be cured and am so tired of living with this disease. Good luck to everyone!

 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on June 21, 2015, 07:25:22 pm
Good luck to you, TXLastTime! :) And welcome to the forums.

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TXLastTime on June 21, 2015, 08:00:50 pm
Thanks Kim. Here are more of my stats since I can access my medical records now. My viral loads when last checked:

03/2015 was 5.24 Million ALT 57 IU/L and AST 35 IU/L.
03/2014 was 6.1 Million ALT 40 IU/L and AST 26 IU/L

Last HIV test was in 2014 and was Negative. Thank god!

Last Liver Biopsy was 06/2014

Tissue: Liver. Clinical Data: Hepatitis C. Diagnosis: Liver, core biopsy: Chronic hepatitis with the following features: · Inflammatory activity: Grade 1 of 4 (minimal periportal inflammation). · Fibrosis: Stage 2 of 4 (portal fibrosis with periportal extension). · No increase in iron stores. · Histologic findings consistent with chronic hepatitis C. Comment: The Batts and Ludwig system was used to grade and stage this liver biopsy. Gross Description: The specimen are four 0.9 cm to 2.2 cm fragments of tan-brown tissue, submitted in toto. BKS:jmm Microscopic Description: The quantity of sampled liver tissue was adequate for evaluation. The portal areas are expanded by a chronic inflammatory process which is almost entirely composed of lymphocytes. The lymphocytes are forming small aggregates within the portal regions. There is minimal extension of the inflammatory process outside the confines of the portal areas. No lobular inflammation is noted. There is no evidence of ductopenia, ductular proliferation, or inflammatory destruction of bile ducts. No granulomas are noted within the portal regions. The hepatocytes have a very mild degree of steatosis, estimated to involve approximately 5% of the hepatic parenchyma. No other hepatocytic abnormalities or pigmentation is appreciated. Central veins appear unremarkable. The trichrome stain demonstrates increased portal fibrosis with focal areas of periportal extension. The reticulin stain shows focal condensation of the hepatic microarchitecture in the periportal regions. The iron stain shows no increase in iron stores. Control material for the special studies stained appropriately.


How does my biopsy compare to others with long term Genotype 3's on here?


 

Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Billy on June 21, 2015, 08:58:58 pm
Down to my last 3 days! A final check up at the VA thurday and then its just a matter of healing my wounded liver with proper nutrition and exercise. Thanks to everyone for the support....it was a rough road for awhile there.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: hepc on June 30, 2015, 08:14:20 am
hi All, Just inished my 2 months, hanging in there, fatigue and pains on the side and liver...other then that i am doing ok i guess. Its still a long journey to go. How is everyone else doing? this message board is a bit quiet. Kimharvest how are things going? did you get to keep going on treatment? Chris when is your svr date? billy how does it feel to get done with tratment? come on guys keep posting...this board needs some life. thanks!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on June 30, 2015, 09:43:09 am
Hi hepc,
Good to see you are on treatment, the time will fly hang in their and don't forget the water!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on June 30, 2015, 05:01:02 pm
Week 5 of 24 weeks riba and sovaldi. 4 week viral load will be resulted by the time my next appointment July 2cnd.
Not sleeping well. Small rash but not bad. Concentration slightly better. Fatigue most likely from not sleeping well. Hemoglobin went up a bit !! Yay me!!
Liver enzymes still normal , but even lower !! Anyone else have ringing in their ears?
19 weeks to go!!! Meds are now coming to my house a huge plus, so no need for the  hour drive just to get my meds. This should be the last of my 2 week appointments. Should be every month after this.
Glad there are some posts. I feel kind of alone in this and your posts really help.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on June 30, 2015, 09:40:06 pm
Hi TexasC

I had some ringing in the ears but it went away, good you are getting the meds delivered. Keep us posted on your VL results. I also felt very alone on this journey, i found it helpful to keep my self busy and exercise (moderate) really helped.
take care
liam
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: hepc on June 30, 2015, 10:28:53 pm
Hi, I also had the ringing in the ear once in a while, i think its normal, did anyone have any pull/tugs slight discomfort in the general liver area?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Justcass on July 01, 2015, 11:05:48 am
Just finished week one of Solv/Riba treatment. So far so good! A little nausea, but my doctor prescribed some meds for it. I hope the rest of the treatment is like this! And I have noticed itching & pain in the right side. :) Hope everyone has a great weekend & Happy 4th of July!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: notnow on July 06, 2015, 12:48:12 am
Hello my hep warriors...hope all is wll w u all. Im going into my 8 th eek of treatment,  doing okay except itching my skin on my arm n legs off, not my best look.....very annoying...trouble sleping also but sooo tired alot of the time. Doctor says my body is handling treatment very well blood results are good and my viral load was undetected at 6 weeks woooooohhhooooo, such good news. I am so scared to be excited and expect to be cured even though my doctor believes I will be. I pray shes right, I am also tired of living with this disease and the fear of spreading it. I had a child while unknowingly infected with this virus and got her tested last week, I should find out tomorrow if shes got hep c, praying n hoping with everything in me shes negative, I cant imagine having her go thru this...wish us luck please..I believe in the power of prayer so maybe u could send one out for her...thank u all for posting and for reading....we are not alone and we can do this

Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on July 06, 2015, 06:32:47 pm
Notnow I am sending up a prayer for great results for your child. Congrats at the great lab results. I am slightly bummed I had a vl of 200 at 3 weeks 5 days.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on July 06, 2015, 07:47:37 pm
Don't be bummed TexasC+, you will clear. I didn't clear until my 6 week labs. And Notnow, I send prayers for your daughter, but I must tell you I unknowingly got hepc with a transfusion with my first child and went on to have 3 more children. They are adults now. They did not get it. In fact, 2 of them donate blood regularly. Congrats on your great lab results. I had my first post treatment labs done last week and am nervously waiting for results. Like you, I am afraid to get my hopes up. Take care all, and God bless.
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LilyGarden on July 07, 2015, 08:24:18 am
Greetings GENO-3 Army!

I just wanted to chime in and thank everyone for their contributions to this thread. I just started a 24 Week Sovaldi + Ribavirin regimen and had no idea this forum and support system even existed until yesterday. I was feeling very alone and now I don’t, so “thank you” to each and every one of you.

I’ve learned more here in these forums in one day than I have from my doctor since this whole ordeal began. I can’t believe how much he’s left me in the dark on some important issues and concerns…now I ‘know what I didn’t know’ and I am equipped to ask the right questions.

Hang in their peeps. And thanks again.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on July 07, 2015, 09:39:01 am
Welcome all,

I also learnt more on this forum than any of the doctors combined. Just drink plenty of water be gentle on yourself. 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: notnow on July 09, 2015, 02:20:49 pm
 :D thank u all for your well wishes...Amazing news is my daughter does not have this nasty disease thank god...And at 4 weeks I also had a viralload of less than 15....at 6 weeks it was undetectable so just hang in there...this is a cure.....and I pray your postlab results are cleared negative for this beast hep c.......thank u again
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on July 10, 2015, 06:46:28 am
YAYYYYYY I got approved till September!! I am sure there will be labs and more Prior authorization's to do then as I don't complete my 24 weeks till December. BUT I am thankful I can get some emotional rest from fighting the insurance battle for a few weeks.
Itchy yesterday and a headache that hung in there. Heat makes it worse and where my stock is at work has no aircondition. Got a truck in yesterday so packing in boxes and stocking stuff most likely didn't help.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on July 10, 2015, 01:36:48 pm
Congrats Mary!! Very good to hear you got your next round of approval so you can focus on healing for a while, not fighting insurance hounds. Astounds me what insurance companies are making people go through. Hang in there! It will be worth it in the end.

best,
kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: mrcat211 on July 11, 2015, 01:00:31 pm
I am desperately trying to start on Medication.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: jberlin on July 11, 2015, 01:38:02 pm
Mrcat:

Your solicitation for funding was removed from the above post.  A lot of our members are fighting the same expensive battle you are, and we are happy to answer questions about finding treatment and various treatment options, but solicitations for money is not allowed on our forums.

Please let me know if you have any further questions. 

Good luck,
jack
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on July 15, 2015, 06:26:16 pm
Hi all!
Good news! SVR12!!!!!!!!!!
I am ecstatic! Today is my birthday and there is no better present than this! I pray to stay this way and get an SVR24 in October. I still have some slight aftereffects, and my hair is still thinning. But otherwise, I feel good, am eating healthier and have more appreciation for the little things in life. I figured I should post this on the string that I started last November as a ray of hope to all. It has been a long tough battle. And the waiting game is the worse!! Lol!
Thanks to all my soulmates on this forum. You all are a tremendous blessing to me and I continue to pray for you all to reach the cure!
God bless.
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: jberlin on July 15, 2015, 07:11:00 pm
Chris,

Congratulations! I have been there and I know how you feel, and it is awesome! 

Please continue to drop in (all of you) on this forum often and cheer on, and console, and counsel, all of our members here going through various stages of treatment and news, whether good or bad.

Way to beat this dragon!
jack
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: hepc on July 15, 2015, 07:31:13 pm
Hi Chris,
Congrats, Excellent news.YAYYYYY! We are all really happy for you. Do you really need a svr24? arent svr12 the last thing and we are done?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on July 15, 2015, 07:37:05 pm
Hi Chris
Well done....so happy for you!!! What sweet letters "SVR" I hope I can join you soon.
Enjoy your new life.
Liam
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on July 15, 2015, 07:53:41 pm
Thank you!
Jack, I will definitely drop in to cheer and console! This forum was more supportive and informational than the doctor! Everyone here has the same battle and no one else could know what they are going through except for people who are on the same journey.
Hepc, yes, you need an SVR24. It's the icing on the cake!! That is considered the cure point.
Liam, you will be joining the SVR team very shortly! Did you have your labs done yet?
I must say, I was sweating bullets and fretting over this test. I feel a great sense of relief! Until October, that is! Lol
Take care, hugs to all!
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on July 15, 2015, 08:07:55 pm
Congratulations  Chris! So happy for you! I'm on week..?? 13,14?.not exactly sure, lol because I've decided to just trudge on knowing in Sept I take the last pills.... I do know I am just past the halfway mark and labs have stayed stable. I will not get a viral check until end of tx because at 5 weeks I already had virus free result. Dr says let's just wait until 24 weeks and last one at 36 weeks. I was told if virus free at 36 weeks then I can use the word CURED and that it is now an accepted term in the medical community. This is a wonderful thing to be truly cured while right now I'm simply termed "in remission". I have missed some evening Riba doses. Not often, but a few times. Just felt saturated, and slightly nutty when I chose to not take a full dose. I know it's wrong, but it is what it is and I now firmly tell myself no matter what, take all pills! Headaches stopped completely, nausea started about 10 weeks in. No biggie, Zofran works. Irritability minor, but present, and slight negative thinking creeps in but all manageable. I'm sharing to help others who have just started. It's not easy but it is very doable. Manage my lifestyle and thinking and I'm great. My Dr and staff at Baylor are so encouraging, makes a huge difference in successful tx.
good luck all!
LisaMarie 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on July 15, 2015, 08:29:21 pm
 Oh, and reply to hepc, yes, the board was way too quiet for awhile. I had just started and was quite dissapointed, but it's back to life now! We each need to hear from each other, symptoms and encouragement! Billy, SO happy you are done with tx!! I know you had a hard time with VA, rashes.... very glad to know you have made it.
To those just starting DRINK WATER! !! and I've noticed the symptoms change. No 2 days are alike. I have "normal" days now and then freakishly crappy days that just slap me in the face saying, oh yea, you're on some powerful meds! But all that does is prove to me that I'm stronger than I gave myself credit for. :) I drank quite a bit before treatment. The first weeks were tough on that front too. I have drank some at week 6 but am back on the proverbial wagon again. It's not hard when I set my mind on what's important and that is healing my body and showing some appreciation for the healing powers of this medicine. Don't get discouraged, I have and when I do I phone a friend and get a pep talk.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Francis60 on July 15, 2015, 08:41:16 pm
Hi Chris,
I just had my 12 week bloods done,as I am on a trial they will not give me the results until 24 weeks, but the nurse said if you don't hear from us within 10 days it means you are clear.I will only be contacted if the have to retest me. So I am having some stressful days ahead.
Good luck to everyone
Cheers
Liam 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on July 15, 2015, 08:50:25 pm
Liam, no news will be good news! Please let me know. Take care!

Lisamarie, keep up the good work! You are over halfway there! It will go faster now! And you are so right, everyday is different! I remember ripping few heads off at work with that riba rage! Take care and keep us posted!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jorah on July 16, 2015, 11:59:28 am
Gee... :o all these posts about rage and anxiety etc are scaring the sh*t out of me, I have to get treated and waited because I thought interferon was bad....but looks like the other meds are as bad... :P  hopefully I'll get 3 meds and may drop one if I get bad sides. Good to hear from the folks that have svr12.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on July 16, 2015, 12:25:00 pm
Hi Jorah! Please don't fear treatment. It has come a long way and it really is tolerable. I work full time at a very demanding job and never missed a day. The riba rage is the irritability and mood swings that the ribavirin can cause. It was not constant, and only caused me to be crabby sometimes and short with people who aggravated me! Lol! Not everyone gets the same sideeffects. But whatever you may encounter, you will find a way to cope with it in your own way. Treatment is far better than living with HCV forever. Good luck to you and never hesitate to ask questions on this forum. Take care.
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jorah on July 16, 2015, 07:27:28 pm
Thanks Chris, I have to see my Hep Docs at the end of the month...see what they think..on which treatment...they already mentioned the 24  week Sovaldi/Riba, but were also hoping for Daklinza to be approved this month or next (that's what Squibb says) maybe 24 weeks with the three. I will also talk to them about Harvoni, but I want it for 24 weeks. I've had it for a long time.
One doctor told me a couple years ago that they also start you with an antidepressant when doing treatment , I don't know if its still valid.
But whatever it is I'm going to do it this time...
Thank you   :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on July 17, 2015, 03:04:04 am
Hip and back pain kicking my butt this past few days. But I have been doing some heavy lifting in the heat. Our stock area has no air condition and I live in Texas. Rash is not bad. Ringing in the ears better.
Congrats CE !!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on July 17, 2015, 06:19:57 am
Jorah, I know in reading the comments about the side effects sounds terrible intimidating, but Chris said it well, the term Riba rage is really a mood affect, an irritability and it is not a constant nor is it uncontrollable. It's an irritability, your normal filter in your brain and sometimes your mouth just doesn't wanna,work! People irritate you some days when normally your mind would work through it or not notice it. I've not missed any work either and I have a stressful job in health profession. I too was frightened of meds. But you can do it with support and arm yourself with knowledge. I had so much anxiety about work/life/meds. Turned out I was wrong is all I can say. It's not interferon. But you do need support. I have anti nausea pills (rarely use), low dose xanax for anxiety, I bought sunscreen, hydrocortisone creams, lol, i was prepared! I am very careful about not eating fast food and drinking lots of water. I rest when I need too, and had family meetings forcing them to acknowledge they understood what this treatment meant to my life as well as theirs! This is called support. We will encourage you. Stay in touch with your nurse too.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jorah on July 17, 2015, 04:41:11 pm
Hey LisaMarie thanks for your reply. sometimes I have this crazy talk that happens in my head  :D I read stuff and I get all worked up about it. You know: what if that happens to me, what if they kick me off TX like Kimharvest because I can't handle it, what if... what if, and you know with my luck...etc etc
I do want treatment, I just want the best one that will kill the virus and that's it...I doubt the plan will pay to repeat the same treatment considering what they charge for it ...but I must also learn to accept that TX  may not work...but maybe a new product down the road may work  ::)

Thanks kindly..
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on July 17, 2015, 05:20:26 pm
Hi Jorah. I think many of us here have gone through that kind of mental turmoil you describe prior to starting our treatment ... "will I be able to handle the side effects? the longer I wait the better the drugs get" etc. So welcome to  the club! :)

In my case I knew I had a good chance of being accepted into the Harvoni+Riba trial that is currently curing me 3 months before the trial actually began. And in those 3 months, I spent a lot of time on these forums reading up. I can tell you, I did a complete 180 in my thinking in that period of time, and it was a very important mental shift for me to make. I am glad I had 3 months "advance notice" before starting my trial so that I could get my head together on this. It is a shift that takes time. I understand exactly what you are going through. I nearly talked myself out of participating in the trial at an early stage in my thinking when I first started reading these forums.

One thing that happens for those of us who have lived with Hep C for years or decades is that we have made our pact with it. We feel we are managing it, can slow the progression of liver disease through our diet, supplements, lifestyle choices, etc. And above all, many of us have become fervent about not letting any toxins enter our body ever - not even once. And so the prospect of a taking a bunch of pills (harsh chemicals in themselves) every day for 12 weeks or longer is something we are going to initially be very reluctant to do. From that paradigm, the logical choice seems to be to continue to live with Hep C "just a little while longer until something better comes along."

In other words, our value system is distorted as a result of the pact we have made with this virus over time to convince ourselves we still have some measure of control over our lives. And that skews our judgment.

In the 3 months lead-in time I had to prepare for my trial, I went from being scared off by the possible side effects, to ultimately fighting to be included in this trial through phone calls, emails, everything I could think of to be the squeaky wheel that gets the grease.

From my reading of all the side effects people were experiencing, I had compiled a 13-page list of protocols I could follow for all the various side effects that might arise (riba rash, riba rage, depression, anxiety, anemia, insomnia, acid reflux, hair loss, high blood pressure, urinary tract infections, cough, nausea, mouth sores, etc.).

By the time I started my trial, I threw the list away (or rather never looked at it again.) My thinking had shifted and I was committed to my new view that NOTHING was as important as removing this virus from my body. (I have probably had it for 45 years.) And I wanted to enter 2016 well, not waiting for an even better cure to come along. I had also "decided" that I wasn't going to have a problem with side effects, that 12 weeks would fly by. And that is what has happened. I have 10 more days to go. Mental attitude is all-important. Our thoughts create our reality.

Wellness to all,
kim

Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on July 17, 2015, 09:29:16 pm
Amen Kim! So true. And Jonah if you go back through my first posts I had the same fears as you express. Kim is correct in the peace we make with the disease which is partially distorted thinking because it does seem to make sense, why put all these powerful meds in your body? Well, I'll tell you why, the Hep C is a powerful destroyer of the liver and the homeostasis of the body and mind, while the meds are a powerful destroyer of the enemy Hep C. Period. I too was prepared for all possible side effects, but 12 weeks in (I counted today finally lol) I can say I had nothing to fear but the fear itself. I'm a coward and control freak when it comes to meds. We are all doing it on this site and you can too. Have faith and know you are not alone.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on July 17, 2015, 09:45:19 pm
Oh, TexasC+, yes, I have ringing in my ears..... I'm used to it. It is very loud too. I was tested at ENT dr and offered hearing aid that puts a tone on the device which x's out the ringing you hear but opted out. Hope that makes sense. Maybe in the future I will.
Just thought I'd share.
Good luck
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on July 17, 2015, 11:39:59 pm
It is really interesting about the ringing in the ears. That is actually what prompted me to see a doctor in the first place and then through testing found the hepc. I developed a very loud ringing in my right ear. I an MRI to check for a tumor and hearing tests. The MRI was negative. (They found nothing in my head, lol!) I do have substantial hearing loss though and was also offered the hearing aid, but declined. Then the doc ordered blood tests and found the elevated liver enzymes. And then it all began! I have to wonder if the ringing is nerve damage from the virus. It is very loud, but like LisaMarie said, I'm used to it now.
Take care.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jorah on July 18, 2015, 08:52:49 am
Thanks Kim and the other replies,  great attitude. I will have to keep that in mind and keep focused.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Justcass on July 21, 2015, 01:42:55 pm
My first month is ending tomorrow, & 5 more to go! The last 2 days I have been getting very dizzy and vomiting a lot. I take my med's with food and somedays are good, but some are terrible. Does anyone else get dizy from these med's????
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on July 21, 2015, 04:09:55 pm
My first month is ending tomorrow, & 5 more to go! The last 2 days I have been getting very dizzy and vomiting a lot. I take my med's with food and somedays are good, but some are terrible. Does anyone else get dizy from these med's????

I have not experienced dizziness on harvoni+ribavirin (and harvoni is sovaldi with another drug, ledipasvir - so it is similar to what you are on). I always think 'blood pressure' when I hear mention of dizziness. can you check your blood pressure - either on a home machine if you have one or at one of those booths in drugstores? low blood pressure (lower than your normal) can certainly cause dizziness - especially upon standing up.

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Justcass on July 23, 2015, 11:17:59 am
Yes, I have one!I will start using it pronto! My doctor just told me im anemic! So I guess that's what's doing this! :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on July 23, 2015, 10:28:35 pm
CE so very happy your done with meds. I can't wait to read your VND in 12 weeks!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on July 24, 2015, 07:20:34 am
Thanks TexasC+! But I already am SVR12! You may have missed my earlier announcement! Needless to say, I am ecstatic with that!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: HeppyChick on July 27, 2015, 12:48:59 pm
Yes, I have one!I will start using it pronto! My doctor just told me im anemic! So I guess that's what's doing this! :)

I researched the anemia problem related to the Ribavirin. It looks like you need to increase your oxygen consumption. How? By doing exercise, aerobic and anaerobic! I force myself to the gym twice a week and my labs are normal.

Oxygen = RBC increase and carry more O2 in the bodies' cells.

Good luck
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks HIV/HCV
Post by: HeppyChick on July 27, 2015, 12:54:15 pm
Week 13......undetectable Viral Load of HCV!!

HIV already been undetectable for 5 years.

This treatment makes me grumpy, lethargic, exhausted at times, and down in the dumps sometimes!

MAIN COMPLAINT??

I have a lot of hair loss. Anyone else?

stay strong and never give up!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on July 27, 2015, 01:40:26 pm
I researched the anemia problem related to the Ribavirin. It looks like you need to increase your oxygen consumption. How? By doing exercise, aerobic and anaerobic! I force myself to the gym twice a week and my labs are normal.

Oxygen = RBC increase and carry more O2 in the bodies' cells.

I agree HeppyChick about increasing one's oxygen intake during ribavirin so that even though your red blood cells are fewer in number due to the hemolytic anemia caused by the ribavirin, they will be carrying as much oxygen as they can pack. I did this mainly through conscious deliberate deep breathing daily (where each inhalation fills and swells your belly first, not your chest). Also sitting up straight. I spend a lot of time in front of a computer for my work. That situation promotes very shallow breathing and often a collapsed posture, both of which minimize oxygen intake tremendously.

I also noticed that my primary muscle weakness due to the riba-anemia occurred for the first hour each morning upon rising. My legs would be so shaky upon rising, I sometimes wondered if they would support my weight. And that makes sense since deep sleep is the time of lowest oxygen intake. So I began doing 10-minutes worth of deep breathing in bed each morning before getting up, and that noticeably improved the shaky-leg problem upon rising.

IMO, deep-breathing is perhaps better for this than hard exercise or gym workouts to increase O2 level in blood. With exercise, although you are increasing your O2, it is because your muscles require more O2 during exercise. So perhaps no net gain in O2 for your organs, brain, other tissues because your muscles are consuming it all. With deep breathing, your muscles don't require more O2, you are simply increasing the oxygen saturation of your blood, which can enrich your organs.

best,
kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: MontanaBlue on July 28, 2015, 10:29:14 pm
Hello All,

New to posting, but have been reading for 14 weeks as this is my 14th week out of 24 -- Geno 3.  I have had the usual side effects.  About 3 weeks ago I have had a hard time breathing, shortness of breath, can't catch my breath.  Got really worried and went to see a Pulmonary Doc.  He said he has had one other person come in with the same side effects. I am an X smoker as of 14 weeks ago. Why not kill two dragons at one time.  Have not had a cig since.  Doc tested me for COPD, don't have that.  Going in for lung xray to see if I have fluid in my lungs.  I will know the results Thur.  He also said I might need an Cardiac Echogram, that is the second step as I could have pulmonary hypertension, NOT GOOD.  Just wondering if anyone else has had breathing problems with these meds - Sovaldi and Rib. I am hoping it is a side effect from meds cuz I just cant handle anymore pressure. I have search the boards and only found on other post about breathing problems.  She never wrote about what her doc said.  I hope she is fine.  Anyway, any one else having breathing problems?  I am really worried as it is getting worse everyday.  Please share your thoughts with me as depression is setting back in.  BTW - Had Hep C since 1980, no other treatment, virus cleared at 4 weeks, Liver biopsy stage 3-4 before starting TX.  I felt what do I have to lose if you know what I mean.  Thanks for reading and look forward to reading your thoughts.  God Bless and thank you to everyone on this site.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on July 28, 2015, 10:46:58 pm
Hi MontanaBlue, Welcome to the forum. Have you reported your breathing problems to your liver doc? This could be caused by the ribavirin, as it destroys your red blood cells making you anemic.  Your then cannot get enough oxygen to all parts of your body, which causes you to be winded easily. This is a common side of Ribavirin, but needs attention. What was your HGB(hemoglobin) on your last blood test? I don't want to alarm you, but increasing shortness if breath is an urgent matter. Please contact your liver doc asap. You may just need a decrease of the riba, or some Procrit to help your red blood cells. My HGB dipped very low (10.3) which caused me to be short of breath on exertion, but did not need treated. Best of luck to you and please let us know how things go. You are in a great forum for info and support.
Take care and best wishes, Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: hepc on July 28, 2015, 10:50:21 pm
Yes had the shortness of breath thing once in a while, very scary, after sovaldi usually. Almost felt like heart was going to stop. hemoglobin fine. just side effect of the meds but always check with your doc anyway.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: hepc on July 28, 2015, 11:30:51 pm
Hi, at the 14 week mark, i dont have rashes but i have alot of ichy pimples daily? is that the rash everyone was talking about?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on August 01, 2015, 04:17:20 pm
Hello All...New to the forum...started on my 5th week of Solvadi/Ribavirin yesterday & will have my 1st lab done on Wednesday 8/5...Hoping for the best but we'll see...Contracted Hep c in 1978 when it was just called non A/B...turned 65 in February & during my "welcome to medicare" Drs appt  it was discovered that I had Hepatitis C Genotype 3a...Always thought I was extremely healthy & all the little annoyances were just part of growing...now I'm not so sure if they weren't part of having this disease running through my body...amazingly I've had no nausea or headaches...I do have a  problem with shortness of breath but I had asthma when I was younger so I'm used to that & how to alleviate it...my main complaint is how tired I feel by at least 2pm everyday...I take my Solvadi & 3 Ribavirin while I'm having breakfast @ 7am & final dose of 2 Ribavirin @ 5pm...so far this time works out for me...I cant wait to see my results & will let y'all know...Thanks to all of you for being there for each other...I'm glad to be part of it... 8)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on August 01, 2015, 06:41:38 pm
Welcome to the forums, Cazbyrd - and to the journey to being cured! I hope you have a smooth ride. :)

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on August 01, 2015, 07:58:24 pm
Welcome Cazbyrd! I find it amazing that we thought all along we were in excellent health while unknowingly living for 30+ years with HepC! Mine was discovered thru a routine well-visit blood work also. I also had some strange annoyances for years, but never in my wildest dreams would I ever have thought I had this. It floored me! 
Eat healthy and be sure to drink lots of water. I wish you all the best as you battle this beast. You WILL win!! Take care.
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on August 01, 2015, 08:22:56 pm
Thanks Kim & Chris...been reading both of your postings from the past week...I've gotten quite a bit of info from both concerning breathing or should I say the lack of...that has been my biggest side effect besides the fatigue but whats one without the other...good food & lots of water...we will all make it.....
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Danster on August 01, 2015, 10:17:13 pm
I haven't been on the forum in a few months. This has been a long journey and I am finally down to 21 days (daze) In a nut shell, for all of those just starting the 24 week treatment, this is doable! I have not missed a day of work yet. I also have an extremely demanding job. In the beginning the hardest thing I encountered was rash and terrible itching. It came on in my 4th week and lasted a month and a half…two months. Glad it passed.For any of you who might encounter itching, I was referred by a member on this forum to get "Sarna lotion with camphor.05% and menthol 0.5%. It was the ONLY thing I tried to provided relief!
I can see the light at the end of the tunnel, finally, and all of you will as well! I tested negative after 6 weeks and have remained so to date. I am convinced that at the end of this, I will be cured of Hep C. I want to wish all of you the VERY BEST. Stay strong and committed! 

Best regards!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Greatful on August 02, 2015, 10:21:08 am
Hi everyone, I have not been on the forum for a couple of months. Glad to see some new members and see everyone doing so well. Huge congratulations to Chris, so happy for you.
The beginning of July my HGB went down to 9.9 and I basically hit a wall physically and mentally. My doctor reduced my Ribovarin from 1000mg a day to 600mg. A week later my HGB was back up to 10.5 and I was feeling much better. I'm still on this reduced does and getting labs this week. I fear this will impede my ability to clear the virus, but my doctor said it will not affect the viral load.
I then went on a wonderful trip to see family in Alaska! I returned home and on July 4th fell in my backyard and broke my wrist :-/
I had surgery a week later and had a plate screwed into my bones to hold everything together. I'm just now starting to focus back on my HepC treatment and wonder if surgery and pain melds I used will have an affect on my treatment outcome.
Anyway, folks I'll let you know how everything turns out. My body is dealing with two big hits, and I'm back at work! You are stronger than you think, just keep pushing through.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on August 10, 2015, 02:58:18 pm
Hello everyone...I'm a little bit disappointed today...got back my results from my 4 week CBC and I fully expected to be undetected but my RNA is detectable @ 18...I know its a drop but..........................anyway my gastro changed my Ribavirin dosage from 1000 to 800 because my Hgb is 9.9...pretty anemic I guess...that answers a lot of questions about my muscle aches & lack of air...just hoping that this will not affect my VL nor the total outcome of my treatment...WOW...my very best to all of you... 8)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on August 20, 2015, 06:57:52 pm
Today is a very special day for me...13 years ago today I put down the needle & have never picked up that bad habit again...Not until this year during a random blood test did I know that I had picked up Hep c...early in 1978 I found out that I had Hep non A/B the same day my Dad found out he was dying of Leukemia...he died that year so I didn't think anymore about my illness...I continued to dabble with drugs off & on for the next 29 years...I guess I'm very fortunate because other than being so very sick in the beginning I have never shown any symptoms...I'm thinking all of these little annoyances over the years such as shortness of breath that I blamed on my asthma & insomnia & fatigue that I blamed on my age was probably due to Hep C...I really am very healthy & will hopefully be amazed at how good I feel once I have beaten this thing...I am very thankful for my treatment...and the time I have yet to live clean sober & virus free..my best to all of you who are fighting this battle along with me & especially to all of you who have fought & Won...

CAROL
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on August 20, 2015, 08:57:14 pm
Congrats Carol on being clean & sober 13 years today! That calls for a celebration! :)

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on August 21, 2015, 03:02:48 pm
Thank You for your well wishes Kim.... 8)

CAROL
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on August 22, 2015, 06:39:47 pm
Week 12 ending tomorrow. Labs are ok. H and H is holding and I am on riba 1200 mg, with sovaldi 400. I am at the half way mark!!
Lots of sleepless nights, I average 2-4 hours. Working a ton of hours.
I am now on every 6 week Dr visits. Next  viral load and labs are sept 2cnd.
Initial viral load 6 million, week 4 200, which doc said dont worry. I am praying for VND !!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on August 22, 2015, 07:07:48 pm
Week 12 ending tomorrow. Labs are ok. H and H is holding and I am on riba 1200 mg, with sovaldi 400. I am at the half way mark!!
Lots of sleepless nights, I average 2-4 hours. Working a ton of hours.
I am now on every 6 week Dr visits. Next  viral load and labs are sept 2cnd.
Initial viral load 6 million, week 4 200, which doc said dont worry. I am praying for VND !!!

Congrats on reaching the halfway mark!! That's a big accomplishment because 24 weeks is a long haul. I know I felt on top of the world when I reached my halfway mark, which for me was just 6 weeks.

Note to everyone on treatment: Do your best to take care of yourselves even though sleep is often hard, and for me diet and nutrition were also very hard since I was experiencing a lot of appetite suppression. And then with the low hemoglobin on top of that from the ribavirin, you can come off treatment in a badly depleted compromised condition, even though you will likely be rid of HCV. I am nearly 4 weeks post-tx, and am basically very sick. I think it is either a never-ending flu or something like that. And I think it is entirely due to the fact that I did not have a proper night's sleep in 12 weeks (usually just 2 hrs a night), I could not eat much, I couldn't eat my usual healthy diet (it didn't appeal at all), and my hemoglobin was below 100 (or 10.0 in some systems) for most of that time. So figure out a way to keep yourself rested and properly fed!

Will go for my 4-week EOT labs on Tuesday, then will get an appt with my GP after that.

best to all,
kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on August 22, 2015, 08:21:50 pm
Hoping for the very best in your EOT labs Kim...I'm also scheduled to have my viral load & labs done on the 2nd of Sept TexasC+...I'm about a month behind you starting mine on July 2nd...Congratulations on your being 1/2 way there...I've only had a few sleepless nights & that was just in the beginning...I take my last 2 Ribas @ 5pm & 1/2 of an Atarax around 9pm..I've not had a problem with my appetite at all...only eating lots of fresh fruits & proteins mostly consisting of chicken cod or salmon...and water...lots & lots & lots of water...there are those days I have to force myself & don't get a s much in me as I should and I can really tell the difference...that's when I suffer with side effects...So Kim you sure are right about keeping yourself rested & properly fed...Blessings to all

CAROL
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: janca on August 24, 2015, 09:56:01 pm
Hi, I am new to the forum and my name is Jan.
I found out I had Hepatitis C genotype 3 three years ago. I have to have a liver transplant 23 months ago.
I recently ended up purchasing my drugs from India and have been taking them two weeks today. I have no numbers but as I am seeing my Doc in two days and I am sure he will take blood and let me know the results.
My side effects have been rough with lack of appetite, upset stomach, off and on headaches, loose stools, as well as just feeling exhausted all the time.
I am drinking lots of water and I have the meal replacement ensure for when I just cannot stomach food.
If any of you can offer me some ideas on how to deal with these side effects I would appreciate it.
Thank you
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on August 24, 2015, 10:08:08 pm
Hi Janca. Sorry to hear you are having so many problems with side effects. I had diarrhea for a week when I was on treatment. Others here recommended the "BRAT" diet for that. I tried it after a week, and my diarrhea stopped almost immediately. Could have been coincidence, but I think it was the BRAT diet: Bananas, Rice, Applesauce, Toast. (Rice and toast are supposed to be white, and applesauce is suppose to be from peeled apples so there is no roughage to irritate/stimulate digestive system.)

Maybe others here will have other suggestions. I too found it hard to eat during treatment.

Best of luck to you,
kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on August 25, 2015, 08:50:05 am
Fortunately I have no problem eating although sometimes I wish I did, lol and one thing I can say is that each week seemed to bring different side effects. I kept my anti nausea medicine readily available, but did not experience nausea until 7 weeks into treatment the beginning was being tired and headache consistently.  NO fast food!  I am Not sure what the correlation is, and it would taste fine to me but I would always end up feeling terrible by the end of the day every single time I ate test one particular fast food restaurant so I skip all processed and fast foods. I am not sure what the correlation is, and it would taste fine to me but I would always and up feeling terrible by the end of the day every single I ate hat 1 particular fast food restaurant so I feel all process and fast food.  Water, water, water! Excercise  a little each day. Irritability a problem  sometimes. But overall I have been able to take all my medicines including supplement and I just go with the flow as far as side effects because they literally do not stay for more than 3 to 5 days and then I will have a few very good normal days.so, this helped me not get discouraged.  I had a lot of family meetings before I started my medicine and I let my boss know as well but my coworkers do not know. They just think I'm crazy I guess but I have not missed any work due to the side effects And much of this is mental. They say, get rest and know that it will be worth it I have 4 more weeks left I am so grateful and honestly there were days when I said no more I don't want to do this anymore! my doctor said that was fine, for 5 minutes then get back on trAck
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on August 25, 2015, 11:25:10 am
Welcome Jan...sorry you are having such a rough time..my first few weeks were pretty bad also but as long as you tell yourself it wont last forever...each day was a new experience & a new side effect but none of them lasted long...just be sure and drink lots of water not just liquids but WATER...the ensure is a good idea tho...I think the Gastro problems are on again off again......our systems are just trying to get used to the killing of these little bugs & they must go somewhere...at least that's what I would tell myself during those many times I spent in the bathroom...I am a third of the way through with 16 weeks to go...doesn't seem so far now but we'll see and good wishes to all of you... 8)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Sookiesue2 on August 25, 2015, 01:14:28 pm
Hi all,

Following this post as I will start the very same treatment on September 9th. Good luck to all of us!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on August 25, 2015, 05:39:23 pm
Hello Sookiesue2...so glad to see you here...many blessings to us all...
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on August 25, 2015, 06:26:43 pm
Hi all,

Following this post as I will start the very same treatment on September 9th. Good luck to all of us!

Hi Sookiesue. Welcome to the forums! That's great that you are set up to start treatment next month. You are in all likelihood on your way to being cured! :)

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Sookiesue2 on August 25, 2015, 06:54:02 pm
Thank you Kim! I hope so :) looks like you are cured and have supported many people in this group. Can't wait to get this over with and be cured once and for all! I'll let y'all my progress :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on August 25, 2015, 07:17:52 pm
Thank you Kim! I hope so :) looks like you are cured and have supported many people in this group. Can't wait to get this over with and be cured once and for all! I'll let y'all my progress :)

I very much hope I am cured. Won't know for certain until late October when I receive the results of my 12-week post-treatment labs. But I am ever hopeful. All of the new drugs have a very high success rate.

best,
kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Sookiesue2 on August 25, 2015, 07:32:07 pm
Fingers crossed Kim!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: janca on August 26, 2015, 12:44:41 am
Hi Janca. Sorry to hear you are having so many problems with side effects. I had diarrhea for a week when I was on treatment. Others here recommended the "BRAT" diet for that. I tried it after a week, and my diarrhea stopped almost immediately. Could have been coincidence, but I think it was the BRAT diet: Bananas, Rice, Applesauce, Toast. (Rice and toast are supposed to be white, and applesauce is suppose to be from peeled apples so there is no roughage to irritate/stimulate digestive system.)

Maybe others here will have other suggestions. I too found it hard to eat during treatment.

Best of luck to you,
kim


Thanks everyone! I started the brat diet today and have increased my water intake even more and I feel better today then I have int he last two weeks,
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on August 26, 2015, 05:51:43 pm
Hi Janca..glad you're feeling better today...Good luck to you each day after...

CAROL
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: janca on August 26, 2015, 07:40:59 pm
Hi Janca..glad you're feeling better today...Good luck to you each day after...

CAROL
thanks Carol.

Today I saw my Doc and the hep C nurse. After filling me in on the legality of obtaining and taking drugs brought in from India they wished me luck, booked my blood test for tomorrow and then again after one month. Lol and after that they asked  for my contact in India...hmmm.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on September 02, 2015, 12:26:53 pm
On week 14 here!! Just had my viral load done this am. VND I hope. Will know in 5-7 days. 10 weeks to go.
I eat some hard cheese every night. I love italian cheese so thats what I choose. Has kept the loose stools under control.
Janica I am glad to read your feeling better. Are the drugs from India the same brand name or generics?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: MontanaBlue on September 06, 2015, 07:33:03 pm
Started week 20 today! Just had VL and still UD. All blood test in normal range. Seems like side effects are tapering off. finally!!! I just hope I don't get another side effect in the next 4 weeks. I must of had all of the side effects. UGH!!! I'm so ready to get off all meds and feel normal again. I will have another VL test done the day after my last pill. I will post my results. Then again in January for the big one.

For all who have just started, please stick with it. It gets easier.

Good luck to all.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on September 07, 2015, 10:00:09 am
Hi everyone, I am down to 2 weeks left! Side effects last week were minimal. I went through some scary times due to some confusion with Specialty pharmacy company and without some help from a WONDERFUL team , nurse, assistant, and Dr I would have been without meds for the 10 days it took to get it all straightened out. It sure makes a difference when your Healthcare team truly cares.
Now just waiting for MRI results concerning septiated complex cyst on liver. It's been of some concern over the last 6 months, and hasn't gone away. I have learned that out Genotype is considered somewhat more aggressive and, as we know by our tx regimine compared to the other G types, it is more stubborn to treat. So theory has it that G3 caused this cyst. It was my hope that it would go away as the Virus was going away..... anyone know if this is possible in time? That IF I beat the virus if the cyst may then shrink and go away.
Thanks.
Much compassion and respect to each of you.
LisaMarie
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: msu on September 08, 2015, 02:55:07 am
Hi Lisa

Nice to hear that you are doing well in the last part of the treatment.

best of luck for your SVR!

Cheers
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on September 08, 2015, 08:30:30 pm
day 2 of week 15. Sept 2cnd lab results today. VIRUS NOT DETECTED!!!! 9 weeks to go after this one.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on September 08, 2015, 08:39:32 pm
day 2 of week 15. Sept 2cnd lab results today. VIRUS NOT DETECTED!!!! 9 weeks to go after this one.

Congrats Mary! :-)

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on September 09, 2015, 11:40:59 am
YAY...went from 18 DETECTED on 4 week labs to <12 UNDETECTED on 8 week labs...Hgb came up from 9.9 to 10.5 after lowering my ribavirin to 800mg...Dr says to stay at this dosage...everything looks good...side effects are minimal...I'm psyched...Congratulations to TexasC+..LisaMarie..MontanaBlue...Good luck to us all...keep drinking that water  8)
CAROL
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on September 12, 2015, 10:38:07 am
Congratulations ! Sending happy and positive thoughts everyone's way.
8 more days.....
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on September 12, 2015, 12:30:23 pm
Best luck to you on SVR coming up soon... 8)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on September 13, 2015, 09:04:36 pm
Does anyone have any positive post tx news to share?
Thanks.
I need it. There's another Hep community site and it's so depressing. I have 7 days left and was looking forward to life after tx.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Greatful on September 15, 2015, 10:05:43 am
Lisa Marie, I have some good news! I posted earlier that I had broken my wrist on 7/4, had surgery & plate implanted 7/10. Everyone was telling me I would have a long recovery, 3-6 months. In 6 weeks I was out of the splint & had impressive bone growth. Now at two months I'm almost back to normal strength & flexibility.

I'm one week behind you in treatment, and so glad this is almost over. Our bodies have amazing healing powers and it sounds like you are doing well. Block out the negative thoughts and comments. Like many on tx, I've had to withdraw from a lot of my social life, and become the one who "rests". My husband has not stopped drinking alcohol in solidarity with me, and continues to go out without me as I'm too tired. Thankfully I have Netflix and four animals to keep me company!

Our six month journey is almost over, let's just be glad we made it! The odds are on our side that we are cured.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Sookiesue2 on September 15, 2015, 10:42:21 am
Congratulations to all of you on your last few days of treatment on Sovaldi/RIBA! I'm way behind you you, only on day 6! So far, so good, side effects have been minimal and hope it stays that way! Like you Gracie, I am pretty much canceling my social life, I live in California where we have the finest wines and love sharing a nice bottle with friends. I was afraid that I would miss it, but so far I'm psyched to make the best out of this 6 months and just take care of my body, not missing my wine yet :) my husband still drinks a little beer, but that doesn't bother me and he stays home with me and my fur babies :) the RIBA gives me bursts of energy and hoping I can use that to accomplish some fun sewing and canning projects this fall. Bought a 1/2 bushel of apples Sunday to can some applesauce and apple pie filling. I was also afraid of insomnia from the RIBA, but have been sleeping like a rock, fingers crossed that continues. I'll be following you guys and wishing us all a hep C free life!

Teri xx
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on September 15, 2015, 01:59:15 pm
Oh Grace, how far we've come!  Thank you both for taking time out of your tx to respond. Teri, please stay positive. It was all such a process for me and the not drinking socially was difficult at first.... anyway, both your posts are right on, I rest and keep to myself. Just trying to move to "recovery from tx" phase, lol.
Much love and respect to you both.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Sookiesue2 on September 15, 2015, 02:19:09 pm
Thanks Lisa Marie! Yea, I passed up our local art and wine festival this weekend and canceling the upcoming Pumpkin Festival as well as a Thankgiving camping trip :( but it's all good, just a bump in the road to good health, which is way more important!  :-*
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on September 15, 2015, 09:31:43 pm
Week 16 here of riba and sovaldi.  I have worked the whole time. Side effects are not to bad : itchy sometimes, do not sleep to well and some headache for an hour or so after the dose. All well controlled by drinking tons of water. I am VND as of 9/2.
This treatment works. I try to eat well, stay busy and get fresh air. I wear sun block as the sun is not your friend on riba.
Insurance denied me at first. My doc took care of the paper work. They told me up front to not worry about denial letters.
Stay positive and remember your 24 weeks will end and you can be cured.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: MontanaBlue on September 15, 2015, 10:27:10 pm
Hello brave ones,

Anyone know why some people are on a 12 week and not a 24 week with Ribavirin?

All have geno 3a....just wondering.

can you take solvaldi without ribavirin?

Peace to all!

Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Sookiesue2 on September 16, 2015, 12:26:05 am
Than you Texas! Did not know about the sun, I walk my dogs every day, at least fall is coming  :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: chuck3a on September 16, 2015, 04:17:52 am
Hello All,
Will be starting my pills in the morning, but not sure if this is the right thread to post on. looks like everyone here is on Sovaldi and Ribavirin. I also have to take Daklinza. so should I start a new thread for this treatment? or did I miss the thread for this combination?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Philadelphia on September 16, 2015, 07:34:32 am
Hi chuck3a and welcome! I started my own thread even though there were a couple of others about similar treatments. I wanted to keep a sort of journal of what I was doing, how I was responding and how I felt.

Feel free to do the same, or piggy back on a thread that is the next best fit if you'd rather.

Good luck! You've already got a sig - you are all over this stuff!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: chuck3a on September 16, 2015, 10:22:13 am
Thanks Philadelphia, I think I am going to start a new thread. due to the fact that adding Daklinza to the mix, it has a some different side effects not covered it in this thread.  Thanks, Chuck
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: badbradley on September 16, 2015, 10:39:22 am
Hello chuck3a             Welcome!  Another new forum member, Mollythedog, may be treating soon on Daklinza. Her posts are on another thread, "will our S/O please post EOT results 4, 12, 24". It is under the topic Post treatment. She has very recently learned of her relapse on 12wks of Sovaldi/Olysio.
    It is a great idea to start a new thread for Daklinza treatment. I hope your treatment goes well. Have a good day!
                                                Brad
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: mollythedog on September 16, 2015, 06:04:14 pm
Hello Cuck,
I too am starting same therapy end of month. Failed on S/O plus 400 ribavirina 12 weeks. I had LT almost 2 years ago then hep C gt1a came backl briinging the new liver to F4 in November last year. Did treatment from March to June then they recommended 24 weeks but it was too late for me. I am now hoping that retreatment will make the difference being 24 wks. I was undetected at 4 and 12 weeks during treatment and had next blood work 12 EOT. so don't know how long I stayed UND. What are the s/e with this? I mean Daklinza? I guess I'll have 1000 /day so probably will experience some s/e this time. Relapse is disappointing to say the least. I wish you a smooth time on treatment and undetected 12/24 weeks after. I'll be catching the same train soon so save me a seat and as you know, a train journey goes much quicker if you have someone to talk to. All the best, Molly
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: mollythedog on September 16, 2015, 06:08:33 pm
Sorry Chuck, I meant 1000 ribavirina.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: chuck3a on September 16, 2015, 10:06:47 pm
Hi molly,
this is what is on the info sheet they gave me
This information is for MALE patients only. it does NOT include important information for FEMALE patients
for daclatasvir aka daklinza.
rash, hives, itching, red, swollen blistered, or peeling skin with or without fever. wheezing, tightness in the chest or throat, trouble breathing or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue or throat. other minor s/e are headache, feeling tired or weak, upset stomach.

 if taken with amiodarone, sofosbuvir and certain other hep c drugs, sometimes it has been deadly, slow heartbeat has happened up to 2 weeks after starting hep c treatment, let your doctor know if signs of slow heartbeat like chest pain, confusion, dizziness, passing out or near-passing out, memory problems, shortness of breath, tiredness or weakness
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: mollythedog on September 17, 2015, 04:07:58 am
Oh my God! Is this only Daklinza or also Ledispavir? Sounds pretty grim doesn't it?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: badbradley on September 17, 2015, 10:21:26 am
Molly
      Here is Daklinza prescribing information.http://www.daklinzahcp.bmscustomerconnect.com/treating/

I do not have the actual paper in hand but usually for those symptoms they advise you to report them to your doctor if any of those develop and that is why they are listed. Those are not common side effects.

Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: chuck3a on September 17, 2015, 11:37:59 am
Thanks Brad,
I really appreciate the link that you did, I am still a newbie on linking in this forum. and to Molly, sorry about scaring you. from what my care team said, they went to a informational meeting about this pill the day before I started my tx and most of the people just experienced the minor s/e.
Chuck
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: mollythedog on September 17, 2015, 04:45:47 pm
Hi all, Molly Here, well thanks to Brad I understand more about resistance but as he said, the more in-depth you go, the more you realise you're unqualified to have full picture of your situation. My doc says Daklinza is pangenotype yet apart from one of Brad's links it seems to be for gt3/3a. I hope this isn't a question of conflict with Gilead. Yes, they want the full treatment to be in house and that could be questionable with my specialist. I must be honest, I'm still working on handing over the problem, spiritually, easier said than done. Sure I don't want treatment less likely to work for me, gt1a f3/4 and transplanted to boot. But I can't stress out on this, I don't want to lose my everyday living.  I teach and translate, take part in occasional short films, help my daughter study at Uni, go swimming 4 times a week (not since relapse last week), I have a dog, Molly, hence the nickname and have short breaks in Tuscany or nice places with my friends now and again. Simple but fulfilling life. All this came as a big surprise in June 2012, hcc formed in late July 2013, chemio ablation partly successful in October and 4 days later a new liver. Shock. Had to let all that out. LT was a great success, hcv not quite so. My prognosis is not good but I really don't want to consider that. I look and feel fine. No s/e from S/O plus riba. I think this filthy bastard
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: badbradley on September 17, 2015, 05:39:32 pm
Hi Molly,
          Don't stress. From links that I provided earlier I concluded that you have a very good chance of clearing on this regimen. It is only FDA approved here in United States for Geno type 3 but in fact is pangenotypic and is very effective for other genotypes.  Hope this helps. Please don't stress out. You are going to clear this time. It can be overwhelming studying this information and some of it is conflicting, mostly because of outdated material.
                                                                                   Brad

http://www.infohep.org/Hepatitis-C-treatment-factsheet-Daclatasvir-iDaklinzai/page/2911744/

I found this also
http://news.bms.com/press-release/rd-news/european-commission-approves-bristol-myers-squibbs-daklinza-daclatasvir-across

http://news.bms.com/press-release/rd-news/european-commission-approves-bristol-myers-squibbs-daklinza-daclatasvir-across

Daclatasvir (Daklinza) has been approved in Europe for use with Sovaldi since August 2014 for multiple genotypes and in those that failed previous treatment that contained an NS3 protease inhibitor.
And I also just found  this 
http://hepatitiscnewdrugs.blogspot.com/2015/05/fda-okays-hep-c-investigational-combo.html

This is encouraging info for your profile. I hope it helps.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: mollythedog on September 18, 2015, 03:56:34 am
Morning Brad,
What a kind person you are. Thank you. I am trying so hard not to stress, yet I dream of hepatitis, treatment combinations, side effects, all kinds of nasty situations. I'll work on letting go again today, all day.  Thanks for the links. Please post when you get treatment approval. All the very best meantime. good luck chuck3a and hope you sail through tx.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on September 18, 2015, 06:51:54 am
MontanaBlue, no! Can't take sovaldi without Riba...
Can't wait to be done. I had very few side effects, but Def had them, I have THREE MORE DAYS!!! I did have headaches (first side effect) water water water solves it.
Then on to 5 days fine and 3 weeks nausea and wow it was a roller coaster IF I paid attention. First day in sun weird line rash, but never again got it and I was out in sun more than I planned because I started my tx in April. Bad idea. Lol. The sun bothered me. It was bright. I'm in texas... alot of things bothered me. I think support, water, staying busy, staying positive, and riding the waves of really, compared to past tx's, minor side effects, no  over all. I admit, some days I was just not happy, some days I was like, "SCREW THIS, I'm not taking any more pills, I quit."... but that's not rational and must be noted that it was part of MY journey, the weird thinking was. I felt weirdly saturated at week 2. Like cotton in every part of me. Full . Saturated. It's mental, I just said YES! GO MEDS KILL THE VIRUS I WILL SUPPORT YOU MEDICATION BY POSITIVE THINKING OR GETTING POSITIVE SUPPORT!
I want you all to know... I never thought I'd make it. I hate meds except fun ones. I like to drink on weekends. I treasure my body, and my mental sharpness. But I did it. I did it. You can too.
LisaMarie
forgive mistakes in spelling and punctuation. I'm on a cell phone
And not gonna check it. :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on September 18, 2015, 07:07:41 am
Another other thought to hopefully help y'all:
  I do work for a Gastroenterologist.... kind of ironic, but I choose not to use my office. Not important why. but anyway It gives me the opportunity to see what real liver disease does, I am able to look in the eye of those with ascites , with those that didn't have this medication and now are desperately fighting for their lives and fighting to now get the medicine when honestly it is probably too late as far as the advanced stages of liver diseas3 they are in. This medicine gives so many people hope regardless It breaks my heart to see the devastation Hepatitis C does on some people's bodies. Please please keep that in mind on the days you get discouraged or think you can't handle it or, like me, wonder what the hell you are doing because you think you might have enjoyed life better and felt better before this treatment. The days you question everything, just remember, Hep C is the enemy to our bodies and this well researched medicine is the closest possibility to a cure we'll ever have.
Wish I could encourage each of you.
please hang in there.
Excercise daily, drink water, get a supportive hug from someone.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Sookiesue2 on September 18, 2015, 10:38:27 am
Than you so much for your inspiration Lisa Marie! I'm on day 8 of Sovaldi/RIBA and almost 2 weekends down without my beloved wine and I feel great. Water, water and more water, exercise, healthy food and a positive attitude that you're killing the dragon has been working foe me so far :) I have a lot of energy and so far the headaches and nausea has been vey minimal, knock on wood!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on September 20, 2015, 09:54:05 am
Your welcome. Please hang in there. I see these harvoni commercials, 8 weeks. 1 pill. Well, we with G3a don't have that 1 pill luxury and must get it in our heads that 6 months is what it is- longer then the 8, more side effects with Riba, but still a huge medical break through for Hep C G3 cure! Ups n downs but mostly the length of tx time was tough for me... but here it is... last day. Wow. Yours will come too. Survive. Conquer, defeat!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Sookiesue2 on September 20, 2015, 10:45:37 am
Congratulations Lisa Marie!! Can't wait for the last pill! Us Genotype 3's do have the longest and hardest treatment and my 10th day here is hardly a dent! This weekend was tough due to a heat wave here at our beach town, so wanted to be on the beach drinking wine but I stayed home and tried to stay productive. Looking forward to cooler fall and winter hibernation weather. I will survive, conquer and defeat!! Can't wait to hear about your 4 week after treatment labs! 22 weeks to go!! Ugh! LOL  ::)

Teri xx
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on September 21, 2015, 06:26:25 am
On to the gym this morning.... day 1 of Phase 2 of treatment: put up all signs of medicine, try to overcome the subtle, low key anxiety that must be a result of the meds, even the psychosomatic effects of TAKING the meds and going to try and  do some light cardio. You know, there are after effects, lingering effects....... doctors can't tell anyone how long or to what degree they last. So, in my mind, 6 month mark is end of phase 1. (Actually phase 1 should be the process of GETTING the medicine....but that's another story.... sigh...), Next 12 weeks is when virus either comes out of hiding from tissues and organs , reproduces, rearing it's ugly head in labs results  >:(  OR, DOESN'T EVER SHOW ITS UGLY FACE AGAIN.  :D ;D
 that's reality folks.
Stay strong, rest, don't get depressed. You can do it!!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: LisaMarie on September 21, 2015, 06:31:37 am
Teri, I live in Texas and summer time is rough here too... always bright, hot, sunny. I agree, winter time is hibernation time and may work better for you as far as heat and social activities! I'm really rooting for each of you who have just started. So much advice to give but really can't because we are all unique in our make up and disease stage. Blanket advice, again ^^^ stay strong, don't give up, seek positivety.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Sookiesue2 on September 21, 2015, 10:41:13 am
Good morning Lisa Marie!

Have fun at the gym and I agree you are in phase 2 and  I pray for phase 2 to be virus free blood work!! I'm on day 11 and am going to yoga today for the first time since I started treatment. I think I'm ready, I've spent the last 11 days getting used to side effects which have been minimal so far. Staying positive! Keep us posted on your after treatment journey, I love following you since we are on the same oh so long treatment :) have a great day!!!

Teri xx
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on September 26, 2015, 08:37:13 pm
Hi there all you GT3's...I'm 1/2 way through Tx as of last Thursday..Yay for me...Sx's have been minimal although I've probably experienced most of them a time or 2...they just didn't hang around very long...I just started my 13th week & thought it would be smooth sailing here on out but I woke up Friday morning with several sores inside of my mouth...I've had these off & on during Tx  but usually go away within a few hours...I also itch like the dickens & feel like a million little creepy crawlies are running all over my body...Wow...whats happening? any ideas from any of you...has this happened to anyone else at this stage? HELP... :-\
Best wishes to all.... 8)
CAROL
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on September 26, 2015, 09:00:54 pm
Hi there all you GT3's...I'm 1/2 way through Tx as of last Thursday..Yay for me...Sx's have been minimal although I've probably experienced most of them a time or 2...they just didn't hang around very long...I just started my 13th week & thought it would be smooth sailing here on out but I woke up Friday morning with several sores inside of my mouth...I've had these off & on during Tx  but usually go away within a few hours...I also itch like the dickens & feel like a million little creepy crawlies are running all over my body...Wow...whats happening? any ideas from any of you...has this happened to anyone else at this stage? HELP... :-\
Best wishes to all.... 8)
CAROL

Hi Carol. Congrats on passing your halfway point! :) As for the mouth sores and itching, I think those are both ribavirin-related. I had both.

For the mouth sores, you can google "oral lichen planus". That might be what's going on. Or it might be something else. Best thing for me was to really double down on oral hygiene - lots of regular brushing and flossing throughout day… more than usual. And rinsing with warm salt water. Swoosh it in your mouth for as long as possible before spitting it out. I think oral lichen planus wants acidic environment, so the alkalinity of salt water lessens it.

As for itching, in my case that was the riba rash, which for me only lasted a couple of weeks coinciding with my night sweats on treatment. And it was confined to my chest and upper back where my wet T-shirt was stuck to my body when I woke up. So I associated it with moisture. I kept that skin as clean as I could with soap and water and then always put potato starch on it to dry it out. The red bumps dried up and fell off and that was the end of it.

Some people with really bad itching problem on treatment are using Gold Bond lotion or benadryl to sleep at night. Mine was never that itchy.

good luck!
kim :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on September 26, 2015, 10:09:34 pm
Thanks Kim...I knew if anyone could help me it'd be you...I started using the warm water & salt & it already feels better...I also googled "oral lichen planus"...alot of good info there...I'll have to get potato starch & give that a try...I live in AZ & the heat is horrendous right now...My skin is super dry & it seems like I'm getting psoriasis on my left elbow...don't know for sure cause never had it before...my sweat feels sticky creamy & yucky all of a sudden like all the demons are leaving my body by any means...I already take Atarax @ night to help me sleep & it controls my itching during that time... we can do this...

CAROL
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TXLastTime on October 03, 2015, 02:25:16 am
Just a update I've been on Solvadi/Riba for about 16 weeks. Geno 3 contracted around 1988-1989 and had a 5million viral load before treatment. I've been un-detectable for the last few months. I have 8 weeks to go under my 24 week plan and then done with treatment. My biggest test is post followup at the 6 month mark. I was un-detectable before and did treatment back about 2 years ago with Interferon/Riba but it came back. I will make sure to throw away all razors/toothbrushes this time. I do not know why it came back and neither do the doctors.

I hope this is my last treatment this time.

I do not deal with stressful situations well under this treatment and I have what you may call RibaRage and have a short fuse. Tired all the time and have to take naps. I will be glad when its over!

 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on October 04, 2015, 10:07:17 am
Tomorrow I start week 19!! Almost there for my 24 weeks. Labs on 9/24 looked good. Last viral load VND.
I eat lots of ice pops and Italian ices this and using good oral hygiene have kept the mouth sores at bay.
As for itch I use sun screen, ivory soap to wash, dreft baby laundry detergent and avoid any processed foods with the exception of the ice pops.
I drink tons of water and on days I dont get as much in I feel more itchy. I don't drink any sodas or juice that's not real juice. NO GRAPEFRUIT juice as its contraindicated with the meds.
Tx last time I am sending up a prayer this is your last time. I found the riba moods to be controlled best by staying busy and positive. I also have a great deal of flowers and plants I tend to in the evening after work, This is a great stress relief. Keep telling yourself " its the medicine and its not me"  that has worked for me pretty well. I also have some utube meditations I have found that  I listen to. I have found a few that have really helped. They are free and I just book marked them on my phone.  Jody Whitley is one I found has lots of them on there but there are a lot of them.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on October 04, 2015, 02:57:01 pm
Already in week 14...moving right along...Had labs done...VL is UND...but Hgb is back down to 9 so Dr lowered my RBV again...I'm down to 400mg...1 in morning & 1 at night...hoping this is enough to keep me from relapsing...the itchy problems I had last weekend were all gone by Monday so it looks like the only SX I have is the Anemia...Everyone have a good day..

CAROL
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: janca on October 13, 2015, 10:14:24 am
Well, it has now been 9 weeks. My viral load is undetectable which is awesome! My anemia is so bad I cannot really function and my riba has been decreased by one pill. I am a little worried as I weigh 206 pounds but the doctor says my blood is totally saturated. Do not have much of an appetite but I am trying to eat healthy and drink lots of water. 15 weeks to go! I hope you all are having an easier time of it then me :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on October 13, 2015, 12:49:08 pm
Ribavirin can have some nasty side effects. I just tell muself its the drug and not me. I will finish and be able to celebrate being hep c free. I have 4 weeks 5 days to go.
Stay the course!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: janca on October 13, 2015, 12:51:12 pm
I am hanging in there :) Glad you are at the end!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on October 13, 2015, 01:35:28 pm
Well, it has now been 9 weeks. My viral load is undetectable which is awesome! My anemia is so bad I cannot really function and my riba has been decreased by one pill. I am a little worried as I weigh 206 pounds but the doctor says my blood is totally saturated. Do not have much of an appetite but I am trying to eat healthy and drink lots of water. 15 weeks to go! I hope you all are having an easier time of it then me :)

Fantastic that you are now undetected janca! Congrats!

Yes, riba can be tough. I just had it for 12 weeks, but the anemia made life difficult and I couldn't do a whole lot. I too had serious appetite suppression during treatment. It was very hard for me to eat healthy on tx but I did my best. I wouldn't worry about being dose-reduced by one pill. Your doctor is right about your blood being saturated with it.

You'll make it through, and a new life will await you! :)

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: janca on October 14, 2015, 04:47:32 pm
Thanks Kim!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: belle3375 on October 15, 2015, 02:11:31 pm
I started treatment 10/9/2015 and so far so good, the most I've experienced is a metal taste in my mouth and occasional head aches. Other than that I'm excited to finally get this going and put it in my past.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on October 23, 2015, 10:08:29 am
What an amazing feeling to open that last box of Riba.( Mine comes in packs of 4 ) 3 weeks 2 days to go!!
24 weeks seems like  a long time when you start , but you get through it.
Not the best morning for me so I am going to do the unthinkable and stay home from work. I never miss and often work 16 -20 hours a day. Riba made me not sleep well so I filled the time with positive and productive work.
The fight is real and the victory is finally possible with new meds.
 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on October 23, 2015, 12:31:54 pm
Hi all,
I started this thread when I started treatment a year ago, and I think it only appropriate that I post my end results on it.
I am so overwhelmed with emotion right now! I just got my 24 week post treatment results and I am SVR24, CURED!!!  I was very apprehensive to hear my results as that fear was always in the back of my mind that is would not work. But ALLELUIA!!
I feel pretty good; my hair is growing again, I lost 12 pounds (eating better and wanting to lose weight), and my outlook on life is so different. I enjoy the little things and find myself more patient and kinder.
I want to thank all my kindred spirits on here for your support and sharing your experiences. You all helped me because only you know how it feels. Bless you all and I wish the very best for you. SVR FOR ALL. It will happen.
Take care.
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: slats1056 on October 23, 2015, 01:55:20 pm
  Super Happy for You CE!!!! Very appropriate, open to close. Long time coming. Your sentiment matches up with My personal message. Just finished Tx. 2 & 1/2 weeks ago and playing the waiting game Myself.  Good to know that the culmination of Your journey is here and that You are SVR and Happy. Big changes behind You as well as ahead!!!!!!
 I know that finding the forums through Lucinda's' blog has helped Me greatly. Always nice to have a sympathetic ear and a virtual shoulder when needed. Good for You and God Bless Us All!!!!!!!!!!!! Time marches on.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on October 23, 2015, 02:20:14 pm
Hi all,
I started this thread when I stared treatment a year ago, and I think it only appropriate that I post my end results on it.
I am so overwhelmed with emotion right now! I just got my 24 week post treatment results and I am SVR24, CURED!!!  I was very apprehensive to hear my results as that fear was always in the back of my mind that is would not work. But ALLELUIA!!
I feel pretty good; my hair is growing again, I lost 12 pounds (eating better and wanting to lose weight), and my outlook on life is so different. I enjoy the little things and find myself more patient and kinder.
I want to thank all my kindred spirits on here for your support and sharing your experiences. You all helped me because only you know how it feels. Bless you all and I wish the very best for you. SVR FOR ALL. It will happen.
Take care.
Chris

Fantastic news, Chris!!! Congratulations on your victory and your new life free of Hep C!  :D

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on November 02, 2015, 06:17:58 pm
Way to go Chris!!! I have 1 week 6 days left of my 24. I can not wait to be done with the treatment.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: mollythedog on November 24, 2015, 11:32:17 am
Hi chuck3 and everyone on sov/daklinza ribs 24 weeks
I relapsed 12 wks Eot on sov/oly riba 400mg for 12 weeks. I am 2 years post transplant hcv relapsed. Week 6 into TX and trying to recover from gastrointestinal virus going around here. Also have anaemia 10.0 last week so now on 600 mg ribavirina till it stabilizes. Feeling quite drained of energy, cold and sleeping badly, very dry skin but no rash. Must drink more water. Well I see all is going well for you Chuck and that's encouraging. After 4 weeks my Vl was 79 from almost 4 mln. Hope to get ud in a couple of weeks, second time around is a little more complicated but I think feeling fluish makes me somewhat negative. Of course I am worried that it may not work again but mainly don't think about results so long away yet. With winter coming in I have to be careful of catching anything as I take immune suppressants to avoid organ rejection. Reading this I sound like a physical wreck !!!!!! Yet I look as healthy as a butcher's knife hahaha. I hate complaining too so it's great to have somewhere to vent my feelings. Do you think 600mg is okay? I'm 5'4" and 8 stones 2 lbs more or less. Well will prepare a quiet evening with a film. Best wishes
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on November 24, 2015, 06:23:00 pm
I finished 11/14/15 most post labs were VND.
I am so happy to not have to have the alarm on my phone go off 2 times a day.
Side effects are greatly reduced. Next lab in 3 months. Post treatment md visit is 12/10/15.
Molly drinking water and staying positive helped me a lot.

CE congrats!!!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: chuck3a on December 02, 2015, 03:22:21 am
Hi Molly,
the riba's may be what is causing the anemia with you, at least it was for me. my GI had me going in for a EOP injection when my HGB dropped to 9.8, and he had me take 1 less riba pill a day. so 4 instead of 5. so I am at 800mg a day now. the first time I got the shot it was at 8.9, 2 weeks later it was at 9.7 right before the second one. when it gets above 10.0, they will stop the injections. I can tell that there is a big change with my being tired and rundown all the time. I feel more active now, not as tired as I was all the time. you may want to look into that if your HGB drops below 10.0. you can google EOP injections, I found it on a mayo clinic information thread. 
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Cal on December 02, 2015, 05:16:24 pm
Hi Molly,
That's good advice from Chuck about the injections. My FBC is still below normal but going up since I stopped ribas 3 weeks ago. I'm still on Viekira Pak. I was on 600mg for a month and then back up to 800mg. I am small like you. So yes 600 is ok. Phily went through her 24 weeks on, I think, 400mg. She might chime in. But I know it was reduced. You'll be fine.
I'm a relapser from the DAAs and ifn and RIBA. So I know your fear. I have it too. Vent on here, you'll get support. I was supported at times when I wad so down and fearful about relapse. It's ok to to realistic but it's not healthy to dwell there too long. Stay posting about your worries. Because you will be ok. If by any chance you do relapse, and if Molly, Merck and Gilead have drugs in phase 3 trials which will cure relapsers in the DAAs. It's ok. Cal :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on December 28, 2015, 02:00:54 pm
Took my last solvadi/ribavirin on 12/17/2015 then had EOT blood tests...am still waiting on my results...this is ridiculous...have always had results within a few days...you'd think the Dr would be the first to understand my dilemma...been on this treatment for 24 long & devastating weeks...need to know whether I am clear of this or not...also am having breathing problems due to the anemia from the ribavirin but need to see my results before I can address that situation...WTF
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Rubi on December 29, 2015, 11:57:47 am
It always takes about 10 days for me to get the RNA (viral load) tests back. Other tests come back quicker. But, that one takes longer. The more important one will be 3 months after treatment. Isn't that when they consider you cured?

Hope you are feeling better soon, no matter what. I just finished 12 weeks of sovaldi/riba. I don't think I could have made 24 weeks with the side effects I was already having.

Please keep us posted.

Rubi
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on December 29, 2015, 04:53:44 pm
Thanks Rubi for the kind thoughts...I'm just a little antsy after 24 weeks of RIBA...I'm glad its done but the results are what I need...
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: CE on December 29, 2015, 09:54:11 pm
Hi Cazbyrd!
I know that feeling all too well! But you got this one! You won! Have faith! Prepare to live again!
Take care and God bless!
Chris
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on December 31, 2015, 11:12:51 am
Thanks Chris...I did get my Labs back & I was UND...just as I thought they were in the drs office all along & signed off by my Gastro @5:30 am on the 23rd...I had to call & call & call & was told they werent even there yet...when I raised enough hell they were emailed to me on the 30th...I guess the right hand doesnt know what the left hand is doing...go figure...going back to my PCP...looks like I've been kicked to the curb by my Gastro...cant make anymore money off of me..SAD...Whew..needed to get that off my chest...my labs look good...everything is on the low side but still in the normal range...will be much better when this RIBA is out of my system...labored breathing...muscle cramps & joint pain...hopefully this will be all gone by the time I reach my SVR12...God Bless to everyone still on treatment & congratulations to those who have  slayed the dragon...



Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: mollythedog on December 31, 2015, 07:18:57 pm
hi everyone and thanks Caz For Your helpful advice.  I'm almost halfway through my second round of DAAs, March to June 2015 sov/oly/riba. Relapsed 12 weeks EOT. October to April sov/daklinza/600riba 24 weeks. 4 weeks vl 71, 8 weeks  vl <12
 ast/alt 25/19 . 5th Jan 12 weeks labs. Felt bad after 3 weeks. RIBA was 800 and I quickly became anaemic, dry skin, itching, dry eyes in the morning, frequently urinating, irritability, no inhibitory barriers when speaking, lost a couple of not real friends. So strange. Cramps like seizures in my feet and legs at night, and others. Most have passed  by drinking more water, cranberry juice, taking calcium and vit D.  Still out of order when I speak (actually I'm swearing, which I always loathed) my daughter finds it quite amusing. But the best thing is that now I can handle the passing s/e and finally I can reach that place inside where the source of strength and peace spring from. More in touch and as it's New Years Eve I'd like to wish everyone a very smooth and peaceful treatment and that this psychologically trying experience is a lifelong success for all of us. That we are ready to have this burden taken from us and most importantly, that we have all learned a lot from this experience, evolved as human beings, changed for our own good and that of all we come in contact with, that we can finally appreciate to the full the beauty all around us, in so many different forms, that it's free and available to us always. That we become less material and more spiritual, that we no longer waste time worrying about things we can do nothing about, and have the insight to solve problems in the right way. And mostly, my greatest wish for me and you all is once again experience times without worry, like when we were kids and felt protected somehow. Enthusiastic and optimistic, creative and that we never deny a smile or a kind word. Blessings to all. Molly
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jorjia on January 03, 2016, 06:23:06 pm
Am new and have a question
.... type 3 on sovaldi and ribavirin. Just started 14th week  of 24.. first month accidently took sovaldi 2 times  same day...tested undetected that month... did same 2nd month ( just stupid I guess ). ..tested undetected. ..just noticed have xtra ribavirin. .missed last week one day....question is did I mess up my treatment. .I will end 2 days earlier because of the 2 sovaldi mistakes and missed a dose of riba
Thanks for any advice
Jim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jorjia on January 03, 2016, 06:28:28 pm
Am new and have a question
.... type 3 on sovaldi and ribavirin. Just started 14th week  of 24.. first month accidently took sovaldi 2 times  same day...tested undetected that month... did same 2nd month ( just stupid I guess ). ..tested undetected. ..just noticed have xtra ribavirin. .missed last week one day....question is did I mess up my treatment. .I will end 2 days earlier because of the 2 sovaldi mistakes and missed a dose of riba
Thanks for any advice
Jim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on January 03, 2016, 06:50:46 pm
Am new and have a question
.... type 3 on sovaldi and ribavirin. Just started 14th week  of 24.. first month accidently took sovaldi 2 times  same day...tested undetected that month... did same 2nd month ( just stupid I guess ). ..tested undetected. ..just noticed have xtra ribavirin. .missed last week one day....question is did I mess up my treatment. .I will end 2 days earlier because of the 2 sovaldi mistakes and missed a dose of riba
Thanks for any advice
Jim

Hi Jim. I am not a doctor, but I don't think you have anything at all to worry about by accidentally shortening your treatment duration by 2 days out of 168. I think the virus will be well and truly gone by that point anyway.

best,
kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jorjia on January 03, 2016, 09:32:40 pm
Thanks Kim
Congrats
didn't know about harvoni and ribavirin.
So you think missing a dose of the ribavirin is ok also or should I try to make it up somehow
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on January 03, 2016, 09:55:46 pm
Thanks Kim
Congrats
didn't know about harvoni and ribavirin.
So you think missing a dose of the ribavirin is ok also or should I try to make it up somehow

From what I have been told by my own treatment team, missing a dose of ribavirin is pretty much irrelevant - especially by the time you are 14 weeks in on a 24-week stint of it. Your body is saturated with ribavirin by that point. Don't forget that many people are dose-reduced on their ribavirin or are taken off it altogether mid-way through if they can't tolerate it (i.e., if they become dangerously anemic). And from what I hear, they are all getting cured as well, even when the ribavirin is reduced or stopped mid-way through.

Harvoni+Ribavirin, the combo I did, seems to be very effective for genotype 3 (a 100% cure rate in the new zealand trial). And it is only a 12-week course instead of 24 weeks like the sovaldi+riba. But so far, I think the Harvoni/riba combo for geno 3 has only been done in clinical trials. So it is not yet being prescribed for geno 3.

good luck! :)
kim

Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Jorjia on January 04, 2016, 08:19:14 am
Thanks for everything
KIM
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: dan98584 on February 04, 2016, 07:11:15 pm
Hi hope this thread is still active. Just started my drug therapy this week. Sovaldi and Ribovirin. Have had hep C since I was 18, am now 60. I'm excited that after a lifetime , I have a chance for a cure. Doc says liver is healthy so far, although apparently a got a boulder stuck in my gall Bladder. Have to take to a surgeon about that. Please Lord one thing at a time. Still working.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on February 04, 2016, 08:32:20 pm
Hi hope this thread is still active. Just started my drug therapy this week. Sovaldi and Ribovirin. Have had hep C since I was 18, am now 60. I'm excited that after a lifetime , I have a chance for a cure. Doc says liver is healthy so far, although apparently a got a boulder stuck in my gall Bladder. Have to take to a surgeon about that. Please Lord one thing at a time. Still working.

Welcome to the forums, Dan! And congrats on starting treatment. You will do fine and in all likelihood be cured by this combo. Just remember to drink plenty of water daily. Helps with side effects. You may experience temporary anemia from the ribavirin at some point during your treatment. But if you do, just remember that it will go away once you finish treatment. Feel free to post any questions or experiences along the way! :)

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: dan98584 on February 04, 2016, 11:12:38 pm
Thanks Kim. Suppose I should google that. Umm off the top of my head, doesn't that mean low iron and tiredness? Or which symptoms are u referring to , with anemia?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on February 04, 2016, 11:39:17 pm
Thanks Kim. Suppose I should google that. Umm off the top of my head, doesn't that mean low iron and tiredness? Or which symptoms are u referring to , with anemia?

Ribarvirin induces hemolytic anemia in many/most people who take it. I experienced that when I did my 12 weeks of Harvoni+ribavirin. It is not iron-deficient anemia. So don't try to compensate with iron supplements. This anemia will result in your hemoglobin and red blood cell count dropping below normal, and yes, you will experience tiredness and shortness of breath. It's all temporary. But you do want to make sure you are getting blood tests, just to ensure that your hemoglobin doesn't drop dangerously low during this period. If a person's hemoglobin drops too low while on ribavirin, the doctor will usually reduce the ribavirin dose. Basically the riba-anemia is just one of those things you get through, knowing that it is part of the thing that is curing you. Some people are more affected by that ribavirin side effect than others.

good luck!
kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: dan98584 on February 05, 2016, 10:39:32 pm
Thx, good info. Part of the reason we get so many labs eh? My 2 week lab on the 15th
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: dan98584 on February 21, 2016, 06:27:39 pm
End of week 3. 21 weeks to go. Sounds so far away. some nausea, little bit foggy at times.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: TexasC+ on February 22, 2016, 06:27:29 pm
24 weeks sounds long, but so worth it. I had lots of side effects but kept going. Drinking lots of water helped. My 3 month follow up was NEGATIVE today.
I took my sov and riba am and pm and never missed a dose. I stayed positive and talked with someone who had done the treatments. You may feel like you can not go on but YOU CAN.
It is so worth it.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on February 22, 2016, 09:09:41 pm
Congratulations TexasC+...you and I are just a month apart...I am now waiting for my 3 month follow up...also stayed positive...sometimes it was hard but oh so worth it...You can do this too...water water & more water...the fogginess will pass... 8)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Sookiesue2 on February 22, 2016, 11:37:36 pm
I have 2 days left!!! Long ass 6 months!! EOT labs next Monday, then stress for 3 months for SVR 12 :) Minor side effect, except for the anemia and insomnia, but I can almost say I'm done! Wishing you all SVR 12!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on February 22, 2016, 11:59:37 pm
Congrats on your SVR12 TexasC+ !!! What a great feeling.  And good luck to all those coming up behind you.

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: AussieRosa on February 23, 2016, 06:41:58 am
Congratulations Sookiesue2 and TexasC+!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: dan98584 on February 29, 2016, 10:08:30 pm
4 weeks down 20 to go>>>>>>>>>>>>>>>>>>>>>>
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on February 29, 2016, 10:19:04 pm
4 weeks down 20 to go>>>>>>>>>>>>>>>>>>>>>>

good work, dan!

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on March 15, 2016, 10:31:17 pm
Tomorrow are my labs...been a long 12 weeks but not as long as the 24 weeks of treatment...I am sure I am cured but will only be positive when my tests say so...I went back to work a month ago after 2 years of retirement...something I couldn't have done prior to beginning treatment...didnt realize how the hepc had affected me...but not any longer...I now have so much energy & truly feel like a 50 year old although I turned 66 the day before I started my new job...I am thankful each & every day for my new lease on life...It is so worth all the bad side effects I had which by the way are pretty much gone..Now I can look forward to the next 30 some odd years... 8) I am BLESSED..so I will be totally surprised if I dont reach SVR12..Good luck to all
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: dan98584 on March 16, 2016, 08:54:57 am
Awesome Cazbyrd! I am 6 weeks along now , in my therapy. My 4 week lab came back as viral load undetected. 18 weeks and counting.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: AussieRosa on March 16, 2016, 11:29:28 pm
Best of luck Dan and Cazbyrd. I'm hoping for SVR for both of you.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: cazbyrd on March 22, 2016, 09:33:32 pm
Just got off the phone with my Dr...I am SVR12..I am cured...Such an awesome feeling...he'll check me in 3 more months...I can honestly say this is the best I've ever felt... 8)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on March 22, 2016, 09:41:00 pm
Just got off the phone with my Dr...I am SVR12..I am cured...Such an awesome feeling...he'll check me in 3 more months...I can honestly say this is the best I've ever felt... 8)

Fabulous news, Cazbyrd! So happy for you!  8)

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kimharvest on March 28, 2016, 01:20:34 am
Congratulations Cazbyrd! Welcome to your new beginning! Give it time!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Johnny_Wayne on May 21, 2016, 02:36:51 pm
Ribarvirin induces hemolytic anemia in many/most people who take it. I experienced that when I did my 12 weeks of Harvoni+ribavirin. It is not iron-deficient anemia. So don't try to compensate with iron supplements. This anemia will result in your hemoglobin and red blood cell count dropping below normal, and yes, you will experience tiredness and shortness of breath. It's all temporary. But you do want to make sure you are getting blood tests, just to ensure that your hemoglobin doesn't drop dangerously low during this period. If a person's hemoglobin drops too low while on ribavirin, the doctor will usually reduce the ribavirin dose. Basically the riba-anemia is just one of those things you get through, knowing that it is part of the thing that is curing you. Some people are more affected by that ribavirin side effect than others.
good luck!
kim

This was great information. Personally, when I heard that Ribavirin causes anemia, my first thought was indeed "iron supplements". This is good to know! Because of cirrhosis, my personal iron levels usually run high enough to suggest hemochromatosis. Self treating with iron could be highly dangerous.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on May 21, 2016, 02:52:56 pm
This was great information. Personally, when I heard that Ribavirin causes anemia, my first thought was indeed "iron supplements". This is good to know! Because of cirrhosis, my personal iron levels usually run high enough to suggest hemochromatosis. Self treating with iron could be highly dangerous.

Yes, self-treating with iron could be very dangerous, Johhny_Wayne. So I am glad you read this. I have read a couple of studies that diets very high in anti-oxidants (berries, fruits, carotenoids) may be useful in slowing and lessening hemolytic anemia. So that can't hurt. :)

good luck!
kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Johnny_Wayne on May 21, 2016, 03:26:23 pm
Where's the "Like" button?  ;D
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on May 21, 2016, 03:28:11 pm
Where's the "Like" button?  ;D

Haha! I know - I've thought the same thing myself many times. If only this were like Facebook. (Except I wouldn't want it to become the time-sink that Facebook is.)

kim ;)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: mollythedog on June 27, 2016, 06:28:16 pm
Hi all,
Just got svr12 on sovdakriba 24 weeks genotype 1a transplanted and relapsed on 12 weeks SovOlyRiba last but June. Slow responder so I would like to say to other slow responder s, don't worry, it means nothing
 I'd like to rejoice but  I can't believe it. Is better it really happening?
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: Johnny_Wayne on June 27, 2016, 07:30:30 pm
Glad to hear! Cheers!
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on June 27, 2016, 07:39:14 pm
Hi all,
Just got svr12 on sovdakriba 24 weeks genotype 1a transplanted and relapsed on 12 weeks SovOlyRiba last but June. Slow responder so I would like to say to other slow responder s, don't worry, it means nothing
 I'd like to rejoice but  I can't believe it. Is better it really happening?

Congrats on your SVR12, Mollythedog! That's great news. :)

kim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: AussieRosa on June 28, 2016, 05:27:47 am
Mollythedog, that's great news. You must be so relieved after all you've been through with this. Wishing you all the very best for your health going forward from here.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: mollythedog on June 28, 2016, 09:47:13 am
Thanks to both of you. Yes it's been very trying. So much so that I am afraid of crying victory till 24 weeks SVR. This whole thing has made me wary. I still can't take it in. I've felt like a walking time bomb on and kept my worry under control for 3 years. I think I need brain washing to let it sink in. But before the forum has been of great help. Especially Kim and the other moderators. Thanks also to youAussie  Rose. I received so much scientific information too. Hope we all get And stay cured.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: KimInTheForest on June 28, 2016, 01:49:34 pm
I'm actually not a moderator. I just blab a lot. Haha! ;) But I agree, the moderators here are great and extremely helpful! :)

I know what you mean about it being hard to believe the news about being cured after all these years with Hep C. It took me quite a while for it to sink in. In fact, it is probably still sinking in.

kim  8)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: mollythedog on June 28, 2016, 07:27:19 pm
Adored Reading your Story Kim. Can really relate to that.<3
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: crabby old guy on June 29, 2016, 11:28:52 pm
Hi, 1st time posting but reading a lot, nice to find a site that is happening now. And my user name says it all!
I'm 57, geno 3, stage 4 cirrhosis. Solvaldi, ribavirin and Daklinza. Started treatment 3/18/16 Get blood drawn every 2 wks. 24 wk treatment. On 4-29 test came back NOT DETECTED and has stayed that way. Side affects didn't kick in till about week 4 and then it was like getting run over by a dump truck. I'm a 2nd shifter and I sleep maybe 4 hrs and then I toss and turn witch doesn't help with my agitation. And I feel like a weepy little schoolgirl watching some tv shows. RBC is low and they cut down on the riba 2 wks in but I still feel run down and exhausted all the time. I see the doc on fri and I hope she say's I'm done. 1st time I saw her she told me there are almost no side affects and that it would be 12 wks. when her nurse called to give me dates for blood work she told me it would be 24 wks, because of my liver. I work in a shipping dept and the confusion and short time mem loss is scary it's to the point that I'm going to ask her if people take off for an extended amount of time because of side affects. Also I'm off right now because of vein things going on in my legs, so I have the added stress of waiting on short term dis to get ok'd. Ok I rambled enough for my 1st post   Thank's Jim
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: FutureThinker on June 30, 2016, 01:21:57 am
COG, welcome to the forums and  glad you found us!  Just want to let you know you have found the right place to vent, or ask questions, or give good news..... this is the place! HCV treatment isn't always fun or easy and there are people here who know exactly what you are going thru. Just hang in there and let those drugs do their thing to get you to the other side, the side of SVR. Keep us posted and the future is bright, FT
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: kimharvest on June 30, 2016, 01:25:36 am
Crabby Old Guy - from crabby old woman, welcome!  This is a very uplifting site because no matter what happens, we are all together.  And we know how it feels.  Just try to hang on, I think us 3a's cure well! But it is hell and doesn't get better fast.  Then you can join us bitching about our side effects. :)
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: AussieRosa on June 30, 2016, 07:42:14 am
hi, CrabbyOldGuy. Welcome to the forum and congratulations on getting treatment for the beast that is hep c. Wishing you all the best for SVR.
Title: Re: Genotype 3, Sovaldi and Ribavirin for 24 weeks
Post by: brie41 on June 30, 2016, 03:04:02 pm
Hi and welcome,

 I think soon you will be calling yourself, not so crabby, new guy!!  I only did 8 weeks, so I can't imagine 24 weeks is any type of walk in the park, but I do hope things get better for you as time goes along.  I can relate to the sleep issues, and I try everything to help my insomnia.  I hate the tossing and turning too.  I had some delicious cherries last night before bed and I fell asleep fairly quickly and stayed asleep.  Actually slept 7 hours which is really good for me.  Once in awhile I take half a xanax, but I really try not to.  I considered melatonin, but I read that your brain will stop producing melatonin so dropped that idea!  Brie