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Hepatitis C Main Forums => Hepatitis C Research News & Studies => Topic started by: FutureThinker on September 09, 2016, 12:51:51 am

Title: The Liver Meeting 2016
Post by: FutureThinker on September 09, 2016, 12:51:51 am
The AASLD's Liver Meeting will be held in Boston this year from Nov. 11 - 15th. I am sure there will be a LOT of new information this year!!  It's really been a stellar year for new treatment options, and such a big graduating class! FT
Title: Re: The Liver Meeting 2016
Post by: elias on November 13, 2016, 01:33:05 pm
Anyone have links for developments at this important AASLD Meeting?

Would be good to keep updated
Title: Re: The Liver Meeting 2016
Post by: elias on November 14, 2016, 05:40:15 pm
ooops!!! sorry

Lucinda Porter is keeping us informed, as usual:

https://www.hepmag.com/blog/highlights-2016-liver-meeting (https://www.hepmag.com/blog/highlights-2016-liver-meeting)

Thanks Lucinda!!

-elias
Title: Re: The Liver Meeting 2016
Post by: Lynn K on November 15, 2016, 08:46:14 pm
Hi Lucinda

Did you see anything of interest for those of us with long standing cirrhosis as far as odds of liver improvement, regression of cirrhosis, or our prognosis in general?

Thanks
Title: Re: The Liver Meeting 2016
Post by: Pete on November 16, 2016, 11:24:47 pm
Small world, I got a note from my Hepatologist just yesterday who is at the Liver Conference in Boston this week.  She mentioned that she's learning about new treatments coming soon for those of us who fail DAA's.  She reassured me by stating that while she believes what I'm doing now (VP/Riba) will work, don't despair because "I will get you cured if it don't..."  Talk about uplifting!  It felt really good to know she took time out of her busy conference schedule send my positive vibes like that. 

I have an awesome doctor and proud to say so!   

Pete
Title: Re: The Liver Meeting 2016
Post by: elias on November 17, 2016, 05:16:10 pm
Lynn wrote:
Quote
Did you see anything of interest for those of us with long standing cirrhosis as far as odds of liver improvement, regression of cirrhosis, or our prognosis in general?

I too am very interested in this. As well as in fibrosis/cirrhosis regression in general.

Wondering if there are things we can actually do to improve odds and degree of such regression after HCV clearance? Not sure this meeting will address that

I already see some report on regression at the meeting. There will probably be more.
Would love to keep updated:

http://hepatitisc.hcvadvocate.org/2016/11/direct-acting-anti-viral-daa-therapy-chronic-hepatitis-c-virus-hcv-infection-associated-regression-liver-fibrosis-assessed-serial-transient-elastography-fibroscan.html (http://hepatitisc.hcvadvocate.org/2016/11/direct-acting-anti-viral-daa-therapy-chronic-hepatitis-c-virus-hcv-infection-associated-regression-liver-fibrosis-assessed-serial-transient-elastography-fibroscan.html)
Title: Re: The Liver Meeting 2016
Post by: Lynn K on November 17, 2016, 09:09:04 pm
What we can do is if we are overweight or obese per our BMI scores is to lose weight as being overweight can contributate to having a fatty liver which will also cause liver problems all by itself.

Also I have read a heart smart diet is a liver friendly diet as well. Really no different than everyone should do maintain normal weight eat health and exercise. I need to do all of those things but easy to say harder to do
Title: Re: The Liver Meeting 2016
Post by: elias on November 17, 2016, 10:15:07 pm
Ty Lynn:

That does simplify it some.

Is "heart smart diet" similar to one for insulin resistance or pre-diabetes?

Oddly enough. I had started such a diet and exercise program a few weeks before my HCV diagnosis.  Still not sure which of the several approaches for this was optimal. Coincidentally, I discovered i was suddenly in pre-diabetic fasting glucose range at same time my family doc noticed spike in my liver enzymes which led him to test me for HCV.

It's interesting, that I came across reference to relationship between insulin resistance and clearing HCV just today:

Quote


Abstract # 912 Impact of Sustained Virological Response to Direct Acting Antivirals on Insulin Resistance in Patients with Chronic HCV - Mostafa G. Elhelbawy, et al.

From:
https://www.hepmag.com/blog/effects-hepatitis-c-treatment-liver-meeting (https://www.hepmag.com/blog/effects-hepatitis-c-treatment-liver-meeting)
Title: Re: The Liver Meeting 2016
Post by: Lynn K on November 18, 2016, 01:25:59 am
I was thinking the heart smart diet from the American Heart Association good general purpose information here is a link

http://www.heart.org/HEARTORG/HealthyLiving/HealthyEating/Healthy-Eating_UCM_001188_SubHomePage.jsp#mainContent

Title: Re: The Liver Meeting 2016
Post by: elias on November 18, 2016, 05:03:45 pm
The relationship between fibrosis/cirrhosis regression and insulin resistance is fascinating to me.

On the one hand, insulin resistance improves much after HCV is cleared. Conversely, diabetes decreases odds of such regression. Diabetes (adult onset) is later stage of insulin resistance. This is best viewed as a continuum.

About one quarter to third of Americans are believed have some form of insulin resistance or other. Increases with age. Most don't know it, and the definition and cutoffs for this change from year to year. It's actually defined arbitrarily , in terms  of cutoff glucose values used. It is quite treatable by diet, weight loss,  exercise, stress reduction, etc.

This bi-directional relationship between HCV and insulin resistance is something I'd like to learn more about