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Advanced Liver Disease Main Forums => Advanced Liver Disease => Topic started by: Hep Editors on July 08, 2019, 11:52:04 am

Title: Immunotherapy Shows Modest Promise for Liver Cancer
Post by: Hep Editors on July 08, 2019, 11:52:04 am
The immunotherapy drugs Keytruda (pembrolizumab) and Opdivo (nivolumab) led to tumor shrinkage in a minority of people with liver cancer treated in real-world clinical practice, underlining the difficulty of treating this type of cancer, according to a set of studies presented at the 2019 International Liver Congress in Vienna.

Over years or decades, chronic hepatitis B or C, heavy alcohol use, fatty liver disease and other causes of liver injury can lead to the development of liver cirrhosis and hepatocellular carcinoma (HCC), the most common type of liver cancer. HCC is often detected late and is difficult to treat. Chemotherapy does not work well against this type of cancer, and most people who use targeted therapies—which interfere with enzymes involved in cell growth and blood vessel formation—experience disease progression or develop unacceptable side effects.

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https://www.hepmag.com/article/immunotherapy-shows-modest-promise-liver-cancer