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Hepatitis C Main Forums => Hepatitis C and HIV Coinfection => Topic started by: Hep Editors on October 08, 2019, 11:31:56 am

Title: Curing Hep C in Women With HIV Is Tied to Reduced Inflammation
Post by: Hep Editors on October 08, 2019, 11:31:56 am
Women with HIV and hepatitis C virus (HCV) who are cured of the latter virus may experience a decline in markers of inflammation as a result, aidsmap reports.

Presenting her findings at the 10th International AIDS Society Conference on HIV Science (IAS 2019) in Mexico City in July, Audrey French, MD, of Cook County Health in Chicago, analyzed the association between curing HCV among women with HIV and biomarkers of what is known as microbial translocation.

Shortly after an individual contracts HIV, the virus wages a massive assault on the gut, causing damage the lining that even very early antiretroviral treatment does not totally reverse. This damage can allow bacteria to leak out of the intestine—this is microbial translocation—which leads to inflammation. In this process, a bacterial membrane component called lipopolysaccharide (LPS) spurs the activation of macrophages and other types of immune cells.

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