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Welcome

Welcome to the Hep Forums, a round-the-clock discussion area for people who have Fatty Liver Disease, Hepatitis B, C or a co-infection, their friends and family and others with questions about hepatitis and liver health. Check in frequently to read what others have to say, post your comments, and hopefully learn more about how you can reach your own health goals.

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Recent Posts

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91
Advanced Liver Disease / FDA Approves Tecentriq Plus Avastin for Liver Cancer
« Last post by Hep Editors on December 02, 2020, 11:39:07 am »
The Food and Drug Administration has approved a regimen combining the immune checkpoint inhibitor Tecentriq (atezolizumab) and the targeted therapy Avastin (bevacizumab) for the treatment of people with inoperable or metastatic hepatocellular carcinoma, the most common type of liver cancer.

In the Phase III IMbrave150 study, Tecentriq plus Avastin reduced the risk of disease progression or death by 41%, prolonged overall survival and improved quality of life compared with standard-of-care treatment.

Read more...
https://www.hepmag.com/article/fda-approves-tecentriq-plus-avastin-liver-cancer
92
Hepatitis C and HIV Coinfection / Gay and Bi Men, in Particular Those With HIV, Have Higher Hep C Rate
« Last post by Hep Editors on November 24, 2020, 01:19:21 pm »
Compared with the general population, hepatitis C virus (HCV) rates are substantially higher among men who have sex with men (MSM), in particular those living with HIV as well as HIV-negative men taking pre-exposure prophylaxis (PrEP), NATAP reports.

Presenting their findings at the International AIDS Conference (AIDS 2020), which was held virtually last week, researchers at the University of New South Wales and the World Health Organization conducted a systematic review and meta-analysis of HCV rates among MSM compared with the general population.

Read more...
https://www.hepmag.com/article/gay-bi-men-particular-hiv-higher-hep-c-rate
93
Hepatitis C Research News & Studies / Hepatitis C Drugs Show Promise Against New Coronavirus
« Last post by Hep Editors on November 23, 2020, 11:53:19 am »
A combination of two antiviral drugs commonly used to treat hepatitis C virus (HCV) were found to shorten the duration of hospitalization and improve survival for people with moderate or severe COVID-19 in a set of studies in Iran, researchers reported at the virtual International AIDS Conference last week.

If larger studies now underway confirm these findings, sofosbuvir and daclatasvir could offer an affordable and widely accessible treatment option, study coauthor Andrew Hill, MD, of Liverpool University said at a press briefing.

Read more...
https://www.hepmag.com/article/hepatitis-c-drugs-show-promise-new-coronavirus
94
Nonalcoholic Steatohepatitis (NASH) / FDA Delays Approval of Ocaliva for Fatty Liver Disease
« Last post by Hep Editors on November 13, 2020, 11:23:52 am »
The Food and Drug Administration (FDA) indicated in late June that it would not approve Intercept Pharmaceuticals’ Ocaliva (obeticholic acid) for the treatment of fibrosis related to non-alcoholic steatohepatitis until more data are available, the company announced. This delays the debut of a first approved therapy for the increasingly common and potentially serious liver condition.

However, as Arun Sanyal, MD, of Virginia Commonwealth University noted at a fatty liver disease symposium sponsored by the Nutrition Obesity Research Center at Harvard, if the agency thought the drug was “ineffective or toxic,” they likely would have stopped an ongoing clinical trial of the drug.

Read more...
https://www.hepmag.com/article/fda-delays-approval-ocaliva-fatty-liver-disease
95
Post Hepatitis C Treatment / Re: 12 weeks post Mavyret treatment and I’m going to lose my mind!!!
« Last post by Lynn K on November 11, 2020, 06:16:23 pm »
All right!!! Great news so happy to hear you made it to 24 weeks SVR.

Enjoy your hep c FREEDOM!!!!!
96
Post Hepatitis C Treatment / Re: 12 weeks post Mavyret treatment and I’m going to lose my mind!!!
« Last post by joy2world on November 11, 2020, 11:19:27 am »
UPDATE!!!! Just got my 24 week post-treatment labs done and I am UNDETECTED!!!! I hope this brings some relief and hope to those out there still testing DETECTED 12 weeks after the end of treatment. I am beyond thrilled! Was seriously contemplating that something was wrong with me or that I had some type of immune issue. Here I am, 24 weeks post treatment and a big fat UNDETECTED!!!
97
Nonalcoholic Steatohepatitis (NASH) / Fatty Liver Disease Is Less Common but More Severe in Women
« Last post by Hep Editors on November 10, 2020, 11:08:11 am »
Women are less likely to develop non- fatty liver disease (NAFLD) than their male counterparts. But women with NAFLD were more likely to progress to non-alcoholic steatohepatitis (NASH) and fibrosis than men with the condition, according to a meta-analysis study published in Clinical Gastroenterology and Hepatology.

“Our findings indicate that once NAFLD is established, the risk of progressive disease (i.e., NASH and advanced fibrosis) is not different and may be slightly higher among women than men,” reported the study authors.

Read more...
https://www.hepmag.com/article/fatty-liver-disease-less-common-severe-women
98
Advanced Liver Disease / Hepatitis C–Infected Livers Can Be Safely Transplanted
« Last post by Hep Editors on November 06, 2020, 10:41:02 am »
Interim results from an ongoing study have indicated that people can safely receive liver transplants from donors with hepatitis C virus (HCV). Transplant outcomes are similar regardless of whether the donor liver was infected with HCV.

Researchers at the University of Cincinnati Medical Center established a cohort of 64 people who needed a liver transplant and divided them into two even groups. One group received livers from donors with hep C; the other group received livers from HCV-negative donors.

The transplants took place between June and October 2018.

Read more...
https://www.hepmag.com/article/hepatitis-cinfected-livers-can-safely-transplanted
99
Hepatitis C and HIV Coinfection / Hep C Testing Following HIV Diagnosis Needs to Increase
« Last post by Hep Editors on November 04, 2020, 11:02:50 am »
People newly diagnosed with HIV are subsequently tested for hepatitis C virus (HCV) at a suboptimal rate.

Guidelines recommend that all people living with HIV receive hep C testing.

Investigators reached this conclusion by analyzing data from the 2003 to 2017 IBM Watson Health MarketScan database, which included information on 46,277 people newly diagnosed with HIV during that time. The study authors published their findings in Open Forum Infectious Diseases.

For more...
https://www.hepmag.com/article/hep-c-testing-following-hiv-diagnosis-needs-increase
100
Nonalcoholic Steatohepatitis (NASH) / Even Lean People With HIV Can Get Fatty Liver Disease
« Last post by Hep Editors on November 03, 2020, 01:23:23 pm »
Almost a quarter of lean people living with HIV had evidence of nonalcoholic fatty liver disease (NAFLD) in a recent study, and nearly one in five of them developed substantial liver fibrosis, putting them at higher risk for cirrhosis and liver cancer, according to a recent study.

NAFLD and its more severe form, nonalcoholic steatohepatitis (NASH), are responsible for a growing proportion of advanced liver disease worldwide, and studies have shown that the condition is common among people living with HIV. Although often associated with obesity and metabolic syndrome—a constellation of cardiovascular risk factors including abnormal blood sugar and blood fat levels, hypertension (high blood pressure) and increased abdominal girth—fatty liver disease can also occur in people of normal weight.

Read more...
https://www.hepmag.com/article/lean-people-hiv-fatty-liver-disease
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