Depression on Sovaldi and Olysio?

[FRED220]

Hello, I read in another site two individuals that shared how they were suffering from depression,I have read lots on Sovaldi and Olysio and have not seen anything that put depression as a side effect. Anyone seen anything?

[lporterrn]

I am not hearing this reported. Anyone else hear this?

[willie g]

WELL I HAVE DEALT WITH DPRESSION DUE TO DIFFERENT HAPPENINGS IN MY LIFE BUT LIKE I HAVE MENTIONED, I HATE CHANGE AND THIS IS A BIG GAME CHANGER IN OUR LIVES AND IF YOUR ANYTHING LIKE ME YOU MAY DWELL ON THINGS ALOT MORE,, IT IS DEPRESSING TO GO THRU THIS WHOLE GIG AND WHEN IT COMES TO DOING THINGS YOUR MIND SAYS GO AND YOUR BODY SAYS NO OR YOUR BODY SAYS GO AND YOUR MIND SAYS NO~!  AHH, WE JUST GOTTA KEEP TRUCKIN AND KEEP SHARING BECAUSE CARING REALLY HELPS. THX  WILLIE G

[Mike]

Simply put, depression can be viewed as endogenous (from within) or exogenous (from without). Endogenous depression is caused by a chemical imbalance within the body. Exogenous depression, on the other hand, is caused by factors outside the body (death of a family member, serious health concern, divorce and so on).

One of the well documented side-effects of Interferon is endogenous depression, as the drug causes a chemical imbalance within the body, leading to depression in some who take it.

I haven't read anything that suggests that Sovaldi and/or Olysio causes depression; but it can't be ruled out.

I do know that a Hep-C diagnosis can cause depression, especially if liver disease is present. I also know that Hep-C treatment sucks and can also be depressive.

My guess is that your depression may be exogenous depression (from without) because of the emotions and feelings about Hep-C and the treatment (much in the same way a cancer diagnosis can cause depression).

I would recommend talking to your doctor about this. I was placed on 20 mg of Paxil while in treatment, though I was taking SOL+INTF+RIBV (depression is common side-effect of INTF).

Remember, keep your eye on the mark (getting cured) and the fact that the treatment is a lot shorter then it use to be. If the depression worsens, talk to your doctor about putting you on an antidepressant.

Best wishes, Mike