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Author Topic: Need Advice Viekira Pak or Harvoni  (Read 21307 times)

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Offline bsmith9876

  • Member
  • Posts: 29
Need Advice Viekira Pak or Harvoni
« on: January 03, 2015, 12:40:01 pm »
Hello, Happy New Year.  Going to my doc monday for tx discussion.  There are now two therapies to choose from and need some advice.

I am G1B, treatment naive, a viral load of <400k, and stage 2 damage.  I think the SVR rates are little higher for Viekira Pak vs. Harvoni. 

Looking at Pearl III info, Viekira is 100% SVR for women with my profile. 
http://www.natap.org/2014/EASL/EASL_59.htm

Or Harvoni for 8 weeks.  At 8 weeks, the ION-3 clinical data shows 95-96% for women with my profile.

Thank you.  Brenda =)

http://www.natap.org/2014/EASL/EASL_10.htm

So thoughts?  I'd love to hear what you guys think.
« Last Edit: January 03, 2015, 12:42:13 pm by bsmith9876 »
G 1b

Offline lporterrn

  • Member
  • Posts: 1,969
  • LucindaPorterRN
    • LucindaPorterRN
Re: Need Advice Viekira Pak or Harvoni
« Reply #1 on: January 03, 2015, 03:19:37 pm »
Hi,
This is a tough one. I'd love to hear what other people think. I'm leaning towards Viekira Pak. You have to be good at remembering to take pills. If you have Express Scripts, it is your only option, but you won't run into red tape.

Let me know what you and your doc decide.
 
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline BattleTheBeast

  • Member
  • Posts: 817
  • Female, 57 - SVR12 as of 7/23/15!!
Re: Need Advice Viekira Pak or Harvoni
« Reply #2 on: January 04, 2015, 05:52:51 pm »
Hi Brenda,

I would go with the Viekira Pak if I was you given the clinical results. Any percentage advantage is still an advantage!!!

I'd just make sure to set alarms on my cell for times I need to take my medication each day since it's more than one time daily with the Viekira Pak.

Best of luck and keep us looped in, can't wait to hear how your treatment goes and for you tell us you are SVR!

Mel
~Mel~
Hep C, Type 1, 10/11  viral load 8,238,340, AST-60, ALT-57 Bili .6  Stage 4 cirrhosis,
Week 4 VL <15 AST 20 - ALT 27 Bili .9
Week 9 - switched to Harvoni VL UD!! AST 20 ALT 19

EOT date is 4/30/2015,
SVR 12 is 7/23/15 ACHIEVED!!! 
and SVR 24 ACHIEVED!!

Offline rainbowray

  • Member
  • Posts: 263
  • Gen 1B
Re: Need Advice Viekira Pak or Harvoni
« Reply #3 on: January 05, 2015, 10:16:19 am »
Hi bsmith,

I am Gen 1B, and have completed Sovaldi/Ribavirin and waiting results.

After going thru treatment and been reading on the forum and such, I think if I did not have treatment and the Viekira Pak was approved, I would go for it since 100% looks very good for Naive. The only thing is since you are female, make sure you are not involved in any of the drugs that are contradictory, especially the birth control ones. Harvoni seems to have less side effects, so consider that also.

If I relapse, I have already arranged with the Dr. to immediately put in for the Viekira Pak, with no hesitation. (I am a male)

Offline bsmith9876

  • Member
  • Posts: 29
Re: Need Advice Viekira Pak or Harvoni
« Reply #4 on: January 05, 2015, 06:19:49 pm »
Thanks everyone for the great responses.

Saw the doc today for the RX.  His reco was Harvoni.  He said that I was a good candidate for the 8 wk.  He said all his patients on Harvoni are having zero to extremely low sides.  He called it a phenomenal breakthrough.

Another point he made was that if for some reason I relapsed on the Harvoni, we could use Veikira Pak as a fallback since it's a different formulation.

It's funny how my doctor and I (who've I have seen since he diagnosed me in 2001) were debating 95% vs. 99% SVR when it used to be in the low 70%'s with peg/inter/riba and really lower for G1b.  It's unreal really.

GAME ON!  He wrote the script.  Now it's in God's hands.

Brenda
G 1b

Offline rainbowray

  • Member
  • Posts: 263
  • Gen 1B
Re: Need Advice Viekira Pak or Harvoni
« Reply #5 on: January 05, 2015, 10:00:33 pm »
I believe you will be cured. sounds like your in good hands.

Offline bsmith9876

  • Member
  • Posts: 29
Re: Need Advice Viekira Pak or Harvoni
« Reply #6 on: January 09, 2015, 05:33:54 pm »
I was approved for the Harvoni!  whewwwwww huge sigh of relief.  The Encompass SP called me today and said I was approved but they have to switch it over to CVS/Caremark Mailorder and they should call me on Monday to schedule delivery.  I also got the $5 copay coupon. 

Thank you for all the advice and kind words. 

Brenda
G 1b

Offline Red Hen

  • Member
  • Posts: 187
Re: Need Advice Viekira Pak or Harvoni
« Reply #7 on: January 09, 2015, 05:41:21 pm »
Congratulations!
genotype 1a
completed 12 weeks Viekira pak and ribavirin
final results due around the end of April
Undetected 12 weeks post treatment!

Offline rainbowray

  • Member
  • Posts: 263
  • Gen 1B
Re: Need Advice Viekira Pak or Harvoni
« Reply #8 on: January 09, 2015, 05:52:20 pm »
 8)  Very Cool

Offline BattleTheBeast

  • Member
  • Posts: 817
  • Female, 57 - SVR12 as of 7/23/15!!
Re: Need Advice Viekira Pak or Harvoni
« Reply #9 on: January 09, 2015, 05:56:44 pm »
Great news Brenda!

You are on the road to SVR!!

Mel
~Mel~
Hep C, Type 1, 10/11  viral load 8,238,340, AST-60, ALT-57 Bili .6  Stage 4 cirrhosis,
Week 4 VL <15 AST 20 - ALT 27 Bili .9
Week 9 - switched to Harvoni VL UD!! AST 20 ALT 19

EOT date is 4/30/2015,
SVR 12 is 7/23/15 ACHIEVED!!! 
and SVR 24 ACHIEVED!!

Offline lporterrn

  • Member
  • Posts: 1,969
  • LucindaPorterRN
    • LucindaPorterRN
Re: Need Advice Viekira Pak or Harvoni
« Reply #10 on: January 09, 2015, 07:35:45 pm »
Fantastic! That is certainly the easier pill schedule to manage.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline bsmith9876

  • Member
  • Posts: 29
Re: Need Advice Viekira Pak or Harvoni
« Reply #11 on: January 09, 2015, 08:04:08 pm »
Thanks ya'll  :)
G 1b

 


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