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Author Topic: Harvoni Results at Week 7 of 8  (Read 18848 times)

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Offline Lukey

  • Member
  • Posts: 319
  • Let Thy Food Be Thy Medicine
Harvoni Results at Week 7 of 8
« on: March 01, 2015, 10:03:17 am »

Last week, week 7 : ALT & AST : 18 / 25 ~ VL : Undetected

I have 3 more days on Harvoni.
I go back for gastro appt and blood work in late March.
« Last Edit: March 01, 2015, 03:31:15 pm by Lukey »
Logged
Male -  HCV since 1982 - Born 1951 ~ Geno 1a

Did 8 weeks of Harvoni in 2015. Got normal AST & ALT and undetected VL by week 5, then relapsed 4 weeks post.
-----------------------------------------------------------
July 5, 2018 : began 12 weeks of Vosevi with a VL of 540,000 and AST & ALT of 65 and 105.
2 weeks in : AST 19, ALT 20
5 weeks in : AST 18, ALT 12, VL "<15 detected"
10 weeks in : AST 19, ALT 14, VL "<15 not detected"
4 weeks post : "<15 not detected"

Offline kate0b1

  • Member
  • Posts: 293
Re: Harvoni Results at Week 7 of 8
« Reply #1 on: March 01, 2015, 12:20:39 pm »
congrats on the great labs and being just about done. stay well

kate
Logged

Offline Mike

  • Member
  • Posts: 999
Re: Harvoni Results at Week 7 of 8
« Reply #2 on: March 01, 2015, 01:25:40 pm »
Congrats Lukey!

That's great news!

Best wishes, Mike
Logged
Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014

Offline bsmith9876

  • Member
  • Posts: 29
Re: Harvoni Results at Week 7 of 8
« Reply #3 on: March 01, 2015, 08:42:47 pm »
Good Deal, Lukey.  High Five!
Logged
G 1b

Offline badbradley

  • Member
  • Posts: 294
Re: Harvoni Results at Week 7 of 8
« Reply #4 on: March 01, 2015, 08:49:26 pm »
Lukey
            That is nice to see and I wish you the best on your next results!
                                                                                          Brad
Logged
Geno 1a
Sov/Oly 12wks - relapse
Har/Riba 12wks
Alt-16  Ast-17 SVR - 12
Alt-15  Ast-14 SVR - 24

Offline Lukey

  • Member
  • Posts: 319
  • Let Thy Food Be Thy Medicine
Re: Harvoni Results at Week 7 of 8
« Reply #5 on: March 02, 2015, 03:58:58 pm »
Thank you for the well wishes for SVR24.

Nurse told me to keep up the way I have been because my Tx is working for me.
I've been exercising often and taking dry heat saunas.
Harvoni seemed to make me feel more chilled and it's been very cold at times lately, but the saunas have helped me with that. 
I've been using my inversion table and other things to increase my circulation, which I think I'll do as long as I live.
A week or two ago I realized I can go to most any gym in town for free with my new Silver Sneakers card, so I went to a gym with dry heat sauna, which I have gotten off and on for several years. I like them, especially in the Wintertime.

Lukey
Logged
Male -  HCV since 1982 - Born 1951 ~ Geno 1a

Did 8 weeks of Harvoni in 2015. Got normal AST & ALT and undetected VL by week 5, then relapsed 4 weeks post.
-----------------------------------------------------------
July 5, 2018 : began 12 weeks of Vosevi with a VL of 540,000 and AST & ALT of 65 and 105.
2 weeks in : AST 19, ALT 20
5 weeks in : AST 18, ALT 12, VL "<15 detected"
10 weeks in : AST 19, ALT 14, VL "<15 not detected"
4 weeks post : "<15 not detected"

Offline dragonslayer

  • Member
  • Posts: 873
Re: Harvoni Results at Week 7 of 8
« Reply #6 on: March 02, 2015, 04:17:40 pm »
Quote from: Lukey on March 02, 2015, 03:58:58 pm
Thank you for the well wishes for SVR24.

Nurse told me to keep up the way I have been because my Tx is working for me.
I've been exercising often and taking dry heat saunas.
Harvoni seemed to make me feel more chilled and it's been very cold at times lately, but the saunas have helped me with that. 
I've been using my inversion table and other things to increase my circulation, which I think I'll do as long as I live.
A week or two ago I realized I can go to most any gym in town for free with my new Silver Sneakers card, so I went to a gym with dry heat sauna, which I have gotten off and on for several years. I like them, especially in the Wintertime.

Lukey

Agreed on the Silver Sneakers card. I belong to 3 gyms.. One I pay for as it's just down the street and has by far the best lifting equipment, and to which I belonged prior to my acquiring a SS card.  One of the SS gyms is open anytime and has card key access, and the other is a posher gym which is not so crowded as my regular pay gym,  and is cleaner, but has somewhat lesser equipment.. Between the 3, there'is hardly a day goes by I dont workout.  Love that SS program :)
Logged
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,546
  • Get tested, get treated, get cured, fight Hep c!
Re: Harvoni Results at Week 7 of 8
« Reply #7 on: March 02, 2015, 11:06:39 pm »
Congrats on finishing tx Lukey

Wishing you SVR 12, SVR 24 and forever SVR
Logged
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Lukey

  • Member
  • Posts: 319
  • Let Thy Food Be Thy Medicine
Re: Harvoni Results at Week 7 of 8
« Reply #8 on: March 03, 2015, 08:11:03 am »
Thank you. :)

I believe that exercise is an important thing for Tx and any other time.
I go to the gym 3x a week, lately early Mon-Wed-Fri mornings.

I had been going to Planet Fitness which is new and only cost me $11 a month.
They had lots of good equipment but no sauna.
I used to pay $48.50 at one gym. It was really nice but I found other gyms that were comparable for less, and now I pay nothing due to my SS card.

Today is my last day on Harvoni. :)

Lukey
« Last Edit: March 03, 2015, 10:16:26 am by Lukey »
Logged
Male -  HCV since 1982 - Born 1951 ~ Geno 1a

Did 8 weeks of Harvoni in 2015. Got normal AST & ALT and undetected VL by week 5, then relapsed 4 weeks post.
-----------------------------------------------------------
July 5, 2018 : began 12 weeks of Vosevi with a VL of 540,000 and AST & ALT of 65 and 105.
2 weeks in : AST 19, ALT 20
5 weeks in : AST 18, ALT 12, VL "<15 detected"
10 weeks in : AST 19, ALT 14, VL "<15 not detected"
4 weeks post : "<15 not detected"

Offline Islandgirl

  • Member
  • Posts: 295
  • Started Harvoni 12/3/14 - EOT 2/25/15
Re: Harvoni Results at Week 7 of 8
« Reply #9 on: March 03, 2015, 09:58:35 am »
Congrats on your last pill, Lukey!  Wishing you SVR forever!  ....Islandgirl 8)
Logged
1b, treatment naive, positive for Hep C since 1994; thought to be transmitted via blood transfusions in 1976
Started Harvoni 12/3/14, EOT 2/25/15
12/31/14 labs - Virus Undetected, ALT/18, AST/34
3/25/15 labs - 1 mo post 12 wk Harvoni TX Virus Undetected!!  :) ....Islandgirl

Offline WaltFrazier

  • Member
  • Posts: 30
Re: Harvoni Results at Week 7 of 8
« Reply #10 on: March 03, 2015, 10:27:23 am »
Great News Lukey! and its so encouraging to read all the UND.  Day 13....
Logged
54 Y-O Genotype 1a Since 1987
TX 2007 48 Weeks INTFR + RIBR ..Hell!
Week 62 Relapse
On Harvoni 12 week
4 Week Undetected!

Offline Lukey

  • Member
  • Posts: 319
  • Let Thy Food Be Thy Medicine
Re: Harvoni Results at Week 7 of 8
« Reply #11 on: March 03, 2015, 01:49:14 pm »
Thank you. :)

Day 13, your ALT & AST are probably in the normal range now. It was with me. :)

Logged
Male -  HCV since 1982 - Born 1951 ~ Geno 1a

Did 8 weeks of Harvoni in 2015. Got normal AST & ALT and undetected VL by week 5, then relapsed 4 weeks post.
-----------------------------------------------------------
July 5, 2018 : began 12 weeks of Vosevi with a VL of 540,000 and AST & ALT of 65 and 105.
2 weeks in : AST 19, ALT 20
5 weeks in : AST 18, ALT 12, VL "<15 detected"
10 weeks in : AST 19, ALT 14, VL "<15 not detected"
4 weeks post : "<15 not detected"

Offline Lukey

  • Member
  • Posts: 319
  • Let Thy Food Be Thy Medicine
Re: Harvoni Results at Week 7 of 8
« Reply #12 on: March 03, 2015, 03:30:46 pm »

I took Magnesium all through my Tx. I figured, if I wasn't responding well, I could have quit it for a while but I seemed to respond really well so I took my Mg 4 hours before & after my mid day Harvoni dose.

I took other things too like Vit E, Vit C, Vit A, but usually 4 hours from Harvoni and so far so good.

Joe
Logged
Male -  HCV since 1982 - Born 1951 ~ Geno 1a

Did 8 weeks of Harvoni in 2015. Got normal AST & ALT and undetected VL by week 5, then relapsed 4 weeks post.
-----------------------------------------------------------
July 5, 2018 : began 12 weeks of Vosevi with a VL of 540,000 and AST & ALT of 65 and 105.
2 weeks in : AST 19, ALT 20
5 weeks in : AST 18, ALT 12, VL "<15 detected"
10 weeks in : AST 19, ALT 14, VL "<15 not detected"
4 weeks post : "<15 not detected"

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,546
  • Get tested, get treated, get cured, fight Hep c!
Re: Harvoni Results at Week 7 of 8
« Reply #13 on: March 04, 2015, 02:12:16 am »
Just a reminder to all

It is best to check with your doctor about all medications you take whether prescribed, or over the counter. As well as herbals and vitamins you may be taking or considering taking while on treatment
Logged
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Lukey

  • Member
  • Posts: 319
  • Let Thy Food Be Thy Medicine
Re: Harvoni Results at Week 7 of 8
« Reply #14 on: March 04, 2015, 12:52:11 pm »
I didn't take a lot of Vit C but I took some (maybe 1-2 grams a day).

My MDs nurse told me to just keep doing what I'm doing at week two and 97 VL, because they were very pleased with my bloodwork results.

Gilead didn't tell me not to take Magnesium either, they just told me to take it 4 hours away from Harvoni.

Harvoni did seem to lower my Magnesium but with me taking Mg every day, I did not suffer low Mg side effects like some people I've read about on here. Why avoid Mg or basic Vitamins if Harvoni is still going to make you Und and normalize your AST & ALT? It didn't make any sense to avoid these things and struggle with the 8 weeks on Harvoni. I used my common sense and it seemed to work just fine for me. They were concerned that something I might take might prevent me from Und status, but that didn't happen. So, I proved (to myself) that Magnesium taken 4 hours from Harvoni, does NOT hinder Harvoni's anti viral actions.

Joe
Logged
Male -  HCV since 1982 - Born 1951 ~ Geno 1a

Did 8 weeks of Harvoni in 2015. Got normal AST & ALT and undetected VL by week 5, then relapsed 4 weeks post.
-----------------------------------------------------------
July 5, 2018 : began 12 weeks of Vosevi with a VL of 540,000 and AST & ALT of 65 and 105.
2 weeks in : AST 19, ALT 20
5 weeks in : AST 18, ALT 12, VL "<15 detected"
10 weeks in : AST 19, ALT 14, VL "<15 not detected"
4 weeks post : "<15 not detected"

Offline dragonslayer

  • Member
  • Posts: 873
Re: Harvoni Results at Week 7 of 8
« Reply #15 on: March 04, 2015, 02:01:43 pm »
Quote from: Lukey on March 03, 2015, 08:11:03 am
Thank you. :)

I believe that exercise is an important thing for Tx and any other time.
I go to the gym 3x a week, lately early Mon-Wed-Fri mornings.

I had been going to Planet Fitness which is new and only cost me $11 a month.
They had lots of good equipment but no sauna.
I used to pay $48.50 at one gym. It was really nice but I found other gyms that were comparable for less, and now I pay nothing due to my SS card.

Today is my last day on Harvoni. :)

Lukey

Planet Fitness... the No Judgement Zone!  Just make sure you dont drop a weight, utter a minor grunt, or look at anybody; Oh, and Definitely no bandanas, doo rags, or skull caps; way too threatening!  Congrats on your last day of Harvoni!
« Last Edit: March 04, 2015, 07:20:52 pm by dragonslayer »
Logged
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,546
  • Get tested, get treated, get cured, fight Hep c!
Re: Harvoni Results at Week 7 of 8
« Reply #16 on: March 05, 2015, 04:07:47 am »
Well for me I wouldn't want to take any risk of a cure for a mere 8 weeks of tx. Instead of going my own way and taking unknown chances I would recommend asking for and following your doctor's advice.

Glad things seem to have worked for you hoping you make SVR 12
Logged
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Lukey

  • Member
  • Posts: 319
  • Let Thy Food Be Thy Medicine
Re: Harvoni Results at Week 7 of 8
« Reply #17 on: March 05, 2015, 09:16:53 am »
I don't think they say to avoid Magnesium, it's antacids along with the Harvoni that they tell you not to take. Even antacids are OK as long as they're taken 4 hours away from Harvoni.

I don't know but it seems like some people get paranoid of not becoming Und and they will avoid things needlessly as if it's going to prevent them from getting SVR.

If I have a relapse I can always do it differently the next time I treat, if need be, but like I said, I didn't want to avoid something they didn't necessarily tell me to avoid in the first place. Magnesium has improved my health in many ways and I didn't want to go without it for 8 weeks. :)

Lukey

I might add that if Gilead doesn't tell us to avoid Magnesium then I doubt MDs are going to, or if they do, they're speculating about some possible interaction of Magnesium with Harvoni that even Gilead is unaware of.
« Last Edit: March 05, 2015, 01:45:25 pm by Lukey »
Logged
Male -  HCV since 1982 - Born 1951 ~ Geno 1a

Did 8 weeks of Harvoni in 2015. Got normal AST & ALT and undetected VL by week 5, then relapsed 4 weeks post.
-----------------------------------------------------------
July 5, 2018 : began 12 weeks of Vosevi with a VL of 540,000 and AST & ALT of 65 and 105.
2 weeks in : AST 19, ALT 20
5 weeks in : AST 18, ALT 12, VL "<15 detected"
10 weeks in : AST 19, ALT 14, VL "<15 not detected"
4 weeks post : "<15 not detected"

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,546
  • Get tested, get treated, get cured, fight Hep c!
Re: Harvoni Results at Week 7 of 8
« Reply #18 on: March 06, 2015, 03:32:57 am »
Sure I agree if the doc says its ok then it is ok. I have a different perspective from my position. If this treatment does not work for me I don't know if I will have time to wait for the next best thing coming.

I cannot risk a 5th treatment failure with cirrhosis for 7 years now how much time do I have left.

Best to you
Logged
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Lukey

  • Member
  • Posts: 319
  • Let Thy Food Be Thy Medicine
Re: Harvoni Results at Week 7 of 8
« Reply #19 on: March 06, 2015, 01:23:28 pm »
I hear you Lynn. :)

Crossing my fingers for both of our long term SVR and eternal normal LFTs.
I think we have a very good chance of it.

I'm not going to fret about it but will make it a point to avoid any possible new sources of viruses.

Congrats on the Und status.  8)

Joe
Logged
Male -  HCV since 1982 - Born 1951 ~ Geno 1a

Did 8 weeks of Harvoni in 2015. Got normal AST & ALT and undetected VL by week 5, then relapsed 4 weeks post.
-----------------------------------------------------------
July 5, 2018 : began 12 weeks of Vosevi with a VL of 540,000 and AST & ALT of 65 and 105.
2 weeks in : AST 19, ALT 20
5 weeks in : AST 18, ALT 12, VL "<15 detected"
10 weeks in : AST 19, ALT 14, VL "<15 not detected"
4 weeks post : "<15 not detected"

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,546
  • Get tested, get treated, get cured, fight Hep c!
Re: Harvoni Results at Week 7 of 8
« Reply #20 on: March 06, 2015, 02:04:52 pm »
Yes I plan to avoid getting any more tattoos from unlicensed tattoo parlors in the future but other that than I have no concerns of contracting hep c again. I am not a medical person giving shots.

As long as I can avoid getting any tattoos or doing any of my other youthful indiscretions  I doubt lightning will strike twice in the same place.

Good luck to you
Logged
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!
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