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Author Topic: severe leg weakness with viekira pak  (Read 7046 times)

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Offline edman300

  • Member
  • Posts: 17
severe leg weakness with viekira pak
« on: November 09, 2015, 04:50:39 pm »
has anyone experienced SEVERE leg weakness while taking viekira pak? I feel like my legs are going to give out on me at any time. Im just wondering if its the meds or something else
thank you
DIAGNOSED IN LATE 80'S
INTERFERON/RIBA-1997-NON RESPONDER
PEGASYS INTERFERON/RIBA-2003-NON RESPONDER
HCV RNA >4,000,000
ALT 33
GGT 25
GENOTYPE-1B/F2
STARTED VIEKIRA PAK W/O RIBA- 8-18-2015 FOR 12 WKS
6wk vl =undetected
alt=12
10 wk vl= undetected

Offline BillT

  • Member
  • Posts: 573
Re: severe leg weakness with viekira pak
« Reply #1 on: November 09, 2015, 05:01:40 pm »
Hi Edman,
              That happened to me once a few weeks back but it was very short(30 min-1 hour).My back has done that to me before so I assumed that was what was causing it.
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: severe leg weakness with viekira pak
« Reply #2 on: November 09, 2015, 05:16:35 pm »
Edman,
Yes I get it and they feel like jelly. I figured it was the ribas, but looks like it could be a Viekira sxs? Cal
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline BillT

  • Member
  • Posts: 573
Re: severe leg weakness with viekira pak
« Reply #3 on: November 09, 2015, 05:31:21 pm »
I'm thinking when these drugs are going through clinical trials it wouldn't be a bad idea to let the patients have a hour a day to just sit and talk among themselves.It seems more information comes out about what's really going on.
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: severe leg weakness with viekira pak
« Reply #4 on: November 09, 2015, 06:45:06 pm »
Bill,
Unfortunately they couldn't give a toss unless it is an Adverse Event eg. death, liver failure. Our sxs are mere tivia to them. They've moved onto the second and third generation of Viekira. I have a friend about to go into a Phase 3 second wave of Viekira Park trial. The bad news it still has ribas with it so far!!!!!

It would be ideal but I think it would be under the muscle weakness sxs listed unless that's in Ribas I can't recall. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline edman300

  • Member
  • Posts: 17
Re: severe leg weakness with viekira pak
« Reply #5 on: November 09, 2015, 07:23:54 pm »
Hey cal, today I took my last dose of my viekira Pak and I will keep everyone updated on how I'm feeling as the meds get out of my system. One thing for sure........ The dragon is gone. PTL. I am very thankful for that
DIAGNOSED IN LATE 80'S
INTERFERON/RIBA-1997-NON RESPONDER
PEGASYS INTERFERON/RIBA-2003-NON RESPONDER
HCV RNA >4,000,000
ALT 33
GGT 25
GENOTYPE-1B/F2
STARTED VIEKIRA PAK W/O RIBA- 8-18-2015 FOR 12 WKS
6wk vl =undetected
alt=12
10 wk vl= undetected

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: severe leg weakness with viekira pak
« Reply #6 on: November 09, 2015, 11:04:43 pm »
Hi Edman,
Congratulations! Yes please keep us updated on your EOT tests and how you are going in yourself. Great news you made it! Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: severe leg weakness with viekira pak
« Reply #7 on: November 10, 2015, 12:28:37 am »
Hey cal, today I took my last dose of my viekira Pak and I will keep everyone updated on how I'm feeling as the meds get out of my system. One thing for sure........ The dragon is gone. PTL. I am very thankful for that

Congrats Edman on reaching End of Treatment! A cause for celebration.

kim :)
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

 


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