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Author Topic: viral load increased on Harvoni?  (Read 7349 times)

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Offline suec

  • Member
  • Posts: 14
viral load increased on Harvoni?
« on: March 24, 2015, 02:08:52 pm »
has anyone or know of anyone, that was successful on harvoni after increase of virus at 8wks from 6.5 baseline to 11.0 at 4wks? wondering if too late for me. or i'm too old, had it too long or just? on borderline of cirrhosis, whatever that means? suppose to do 12 wk treatment and now maybe i'll need 24 wks? and will they pay for it is the next big question? thanks

Offline Momof3

  • Member
  • Posts: 55
Re: viral load increased on Harvoni?
« Reply #1 on: March 24, 2015, 02:34:04 pm »
I can't say I know what would be the course of action for yourself... But I offer a hug for you!!
Hep c GT 1a from transfusion at birth 1986
Treatment naive
Stage f0-f1 fibroscan score 2.5kpa
Harvoni started 02/11/2015 8 weeks
Baseline VL 689,594 ALT 35 AST 25
2 weeks ALT 13 AST 16
4 weeks VL <15 detected ALT 12 AST 15
 UNDETECTED  at EOT April 7
4 weeks post Harvoni UNDETECTED ALT 10 AST 14
12 weeks post Harvoni UNDETECTED ALT 8 AST 15
24 weeks post Harvoni UNDETECTED ALT 13 AST 18

CURED!!!!

Offline dragonslayer

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  • Posts: 873
Re: viral load increased on Harvoni?
« Reply #2 on: March 24, 2015, 03:05:15 pm »
has anyone or know of anyone, that was successful on harvoni after increase of virus at 8wks from 6.5 baseline to 11.0 at 4wks? wondering if too late for me. or i'm too old, had it too long or just? on borderline of cirrhosis, whatever that means? suppose to do 12 wk treatment and now maybe i'll need 24 wks? and will they pay for it is the next big question? thanks

Are these logarithmic measurments?  Is this an increase from 6.5mil to 11 mil iu/Ml  during 4  wks of Harvoni?  Ive never heard of anything like this.
« Last Edit: March 24, 2015, 04:28:08 pm by dragonslayer »
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline suec

  • Member
  • Posts: 14
Re: viral load increased on Harvoni?
« Reply #3 on: March 24, 2015, 06:14:15 pm »
Paul,
Thanks, I had it all wrong! It was the HCV Antibody, HepC Virus Ab that was >11. Saw my doc today and he said I was doing great HCV Not Detected! I got a copy of the test and still don't get what the #s mean? But sure do know what Not Detected means! Means I can hopefully get some of my health back. And no more damage to liver from HepC. Have 6 wks to go and then more blood work and then again at 6mos post treatment and hopefully all stays good,very happy, Yeah, hope it lasts!!Thanks for getting back to me. Too bad my doc doesn't explain very well and the on line results from the lab don't explain nothin'. the HCV antibody I think, is something that will never go away. But the point is no new replication and my liver gets a long awaited break from being attached. Have a good night.

Offline dragonslayer

  • Member
  • Posts: 873
Re: viral load increased on Harvoni?
« Reply #4 on: March 24, 2015, 06:56:58 pm »
That's fantastic news; a whole lot better than you were fearing.  Congratulations!
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

 


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