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Author Topic: Can someone tell me what this means??  (Read 12050 times)

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Offline davidsconfused

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  • Posts: 53
Can someone tell me what this means??
« on: April 28, 2015, 05:29:22 am »
HEPATITIS C RNA QUANT (>43IU) / QUAL (>7IU) (87522)
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Offline GLCII

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  • Posts: 127
Re: Can someone tell me what this means??
« Reply #1 on: April 28, 2015, 09:42:09 am »
The fist part (>43iu) looks like the lower limit of a test used in one of my blood test last year. What is the test they're using for your PCR RNA Quantative? Mine is the Roche Cobas.

Is that exactly how it looks in the lab report?

HEPATITIS C RNA QUANT (>43IU) / QUAL (>7IU) (87522)

" The lowest viral load this assay can accurately quantify is 43 IU/mL, but the limit of detection is 7.1 IU/mL for genotype 1 viruses, and 10 IU/mL for viruses with all other genotypes. "

Hope this helps
« Last Edit: April 28, 2015, 09:53:27 am by GLCII »
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Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline Philadelphia

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  • It only looks like I know what I'm doing
Re: Can someone tell me what this means??
« Reply #2 on: April 28, 2015, 09:52:32 am »
Well, I'm not entirely sure but this is a snippet of an email from my nurse specialist when
I was asking which VL test to ask for at my local hospital:

"The qualitative is more sensitive than a quantitative. The HCV RNA Taq Man is more sensitive again but we are only talking about a tiny variation. Taqman can read <15 copies, qualitative <50 copies and quantitative <600 copies(that is with a Roche assay)"
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CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline GLCII

  • Member
  • Posts: 127
Re: Can someone tell me what this means??
« Reply #3 on: April 28, 2015, 09:55:01 am »
Here's something I found

The lowest viral load this assay can accurately quantify is 43 IU/mL, but the limit of detection is 7.1 IU/mL for genotype 1 viruses, and 10 IU/mL for viruses with all other genotypes.

HEPATITIS C RNA QUANT (<43IU) / QUAL (<7IU) (87522) I think it should look like this.

http://education.questdiagnostics.com/faq/hcv-rna-pcr


I hope this helped.

« Last Edit: April 28, 2015, 09:58:12 am by GLCII »
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Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline davidsconfused

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  • Posts: 53
Re: Can someone tell me what this means??
« Reply #4 on: April 28, 2015, 10:33:25 am »
My doctor's office just put this up on my patient portal last night from a blood test 3 weeks ago, where I was told the HCV wouldn't be run until EOT. When I went in the week after this test nothing was mentioned except they went over the regular blood test items (my potassium is low, blaa, blaa). This report is dated that same date I was in the office so I don't think it came in later.

What I posted is what's on the report, I copied and pasted. That's all there is about this except for the date. Is this good, bad, horrible or what? I'm freaking right now because I only have three days of Harvoni to go, have no idea what's going on and no one from my doctor's office has returned my call.
« Last Edit: April 28, 2015, 10:35:23 am by davidsconfused »
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Offline davidsconfused

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  • Posts: 53
Re: Can someone tell me what this means??
« Reply #5 on: April 28, 2015, 10:40:09 am »
Quote from: GLCII on April 28, 2015, 09:55:01 am
Here's something I found

The lowest viral load this assay can accurately quantify is 43 IU/mL, but the limit of detection is 7.1 IU/mL for genotype 1 viruses, and 10 IU/mL for viruses with all other genotypes.

HEPATITIS C RNA QUANT (<43IU) / QUAL (<7IU) (87522) I think it should look like this.

http://education.questdiagnostics.com/faq/hcv-rna-pcr


I hope this helped.

I see what the difference is on yours now, the < > are opposite what's on mine. What I have is not a copy of the actual report from the lab, someone typed this in I think. I wonder if whoever typed this inverted the symbols?
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Offline GLCII

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  • Posts: 127
Re: Can someone tell me what this means??
« Reply #6 on: April 28, 2015, 11:00:17 am »
I don't think what you're seeing is the blood test results for your test. I think you're seeing what the test can see but doesn't have your results in it.

It can accurately count (quantify) 43 and see down to 7. The basic parameters of what your test can do is what your seeing.

Don't Freak Out. You're good. Read that link I posted and that should calm you down.
« Last Edit: April 28, 2015, 11:07:51 am by GLCII »
Logged
Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline davidsconfused

  • Member
  • Posts: 53
Re: Can someone tell me what this means??
« Reply #7 on: April 28, 2015, 11:06:34 am »
Quote from: GLCII on April 28, 2015, 11:00:17 am
I don't think what you're seeing is the blood test results for your test. I think you're seeing what the test can see but doesn't have your results in it.

It can accurately count (quantify) 43 and see down to 7. The basic parameters of what your test can do is what your seeing.

Thanks, I think from this I figured it out (I hope). I think this is the test they scheduled during that visit for my EOT. This makes more since as I was told all along that there wouldn't be a HCV test until the EOT.

Freak off now.  :P
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Offline GLCII

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  • Posts: 127
Re: Can someone tell me what this means??
« Reply #8 on: April 28, 2015, 11:11:28 am »
I think what you're seeing is what the test can see and do. It's Not Your Test. I can imagine that feels like a bad acid trip eh?

If you read the link it pretty much explains it. It's just hard for us non-medical personel to read it. But we can figure it out.

Tell your doctor you want a test done. If you've been on Harvoni for over 2 weeks I'd say your negative.
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Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline GLCII

  • Member
  • Posts: 127
Re: Can someone tell me what this means??
« Reply #9 on: April 28, 2015, 11:15:43 am »
This is what my test looked like last Feb. 14th 2014

HCV results (IU)   12043488
HCV result (LOG)   7.08
HCV comment   The lower limit of quantitation is 43 IU/mL.
Test performed by Roche COBAS Ampliprep/COBAS TaqMan HCV Test

Here's what it looks like now
HCV comment   The lower limit of quantitation is 15 IU/mL
HCV RNA Not Detected

Which is what yours will probably look like.
Logged
Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline ponygirl

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  • Posts: 39
Re: Can someone tell me what this means??
« Reply #10 on: May 01, 2015, 08:59:31 am »
I wish mine said that; at my 2 week it was <15. But no undetected. I am hoping that the sensitive little machine was just reading deceased and partial strands.
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Offline MEG

  • Member
  • Posts: 304
Re: Can someone tell me what this means??
« Reply #11 on: May 02, 2015, 08:46:53 pm »
@ponygirl.

After 2 week treatment <15? That's awesome. You've had a strong early response...Be happy. By now you're probably undetectable....

Cheers!
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Geno 1a. IL28B+ with TT polymorphism.
Diagnosed 1993.
Liver Biopsy 1993 --inflammation.
Fibroscan 2014---no fibrosis.
ALT range---60s
AST range---80s.
Platelets: 200K range.
Viral load--2 million range.

Began Harvoni on January 23.
Finished 12 week course on April 19.

May 18---4 week EOT labs:
VL: UNDETECTED.
AST: 23
ALT: 22...........These have not been this low throughout treatment and since my 20s.

12 weeks EOT on July 15---Undetected.
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