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Author Topic: Harvoni vs viekira pak  (Read 7069 times)

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Offline edman300

  • Member
  • Posts: 17
Harvoni vs viekira pak
« on: August 19, 2015, 09:38:54 pm »
It seems like most people if they had a choice would much rather get harvoni instead of viekira pak.  I'm just wondering what if anything is so undesirable with viekira pak. I started viekira pak 2 days ago and would love to hear from some of you experienced bloggers wisdom you have learned along the journey.  Thank you for a place that I can go for support
DIAGNOSED IN LATE 80'S
INTERFERON/RIBA-1997-NON RESPONDER
PEGASYS INTERFERON/RIBA-2003-NON RESPONDER
HCV RNA >4,000,000
ALT 33
GGT 25
GENOTYPE-1B/F2
STARTED VIEKIRA PAK W/O RIBA- 8-18-2015 FOR 12 WKS
6wk vl =undetected
alt=12
10 wk vl= undetected

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: Harvoni vs viekira pak
« Reply #1 on: August 20, 2015, 03:40:35 pm »
Besides Viekira Pak being less convenient that Harvoni's one pill a day, those with Genotype 1a (with or without cirrhosis) and Genotype 1b with cirrhosis must take Ribavirin along with Viekira Pak, which can add side effects from the Ribavirin. Fewer Harvoni users need to take Ribavirin in addition to Harvoni.

edman300, are you are taking Viekira Pak without Ribavirin? In that case, the only differences that I'm aware of are taking more pills and needing to take them with food (Harvoni can be taken with or without food). The Viekira Pak cure rates look excellent. Best wishes to you.
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline edman300

  • Member
  • Posts: 17
Re: Harvoni vs viekira pak
« Reply #2 on: August 20, 2015, 03:51:27 pm »
Yes i am genotype 1b without cirrhosis so I don't have to take ribovarin.  Thank God.  I did 2 different regiments of interferon with ribovarin.  It almost did me in. Thanks for the input and encouragement.  I appreciate it and best wishes to you as well 
DIAGNOSED IN LATE 80'S
INTERFERON/RIBA-1997-NON RESPONDER
PEGASYS INTERFERON/RIBA-2003-NON RESPONDER
HCV RNA >4,000,000
ALT 33
GGT 25
GENOTYPE-1B/F2
STARTED VIEKIRA PAK W/O RIBA- 8-18-2015 FOR 12 WKS
6wk vl =undetected
alt=12
10 wk vl= undetected

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: Harvoni vs viekira pak
« Reply #3 on: August 20, 2015, 04:07:04 pm »
Since you are treatment-experienced without cirrhosis, it's 12 weeks with either drug, so there's no difference there either. Bon Voyage!
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline Philadelphia

  • Global Moderator
  • Member
  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: Harvoni vs viekira pak
« Reply #4 on: August 20, 2015, 04:40:11 pm »
What gnatcatcher said. Without riba increased pill burden, different drugs (more or less) so therefore increased drug interactions to watch but really apart from that, success rates are pretty similar.
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

 


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