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Author Topic: Trouble Swallowing Large Viekira Pak Pill  (Read 7258 times)

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Offline Lorangerboy

  • Newbie
  • Posts: 1
Trouble Swallowing Large Viekira Pak Pill
« on: January 11, 2016, 07:18:16 pm »
I was excited to start my treatment this morning.  I was home alone and opened the first Viekira Pak and took out the larger 2 pills.  Put the first one in my mouth took a big drink of water, swallowed, and it lodged in my windpipe.  I could not breathe.  I tried taking another drink, but it wouldn't move.  I ran outside on my carport hoping someone would see me if I happened to pass out.  It was that serious.  Finally I caught a little bit of air.  The pill moved down a little.  That shook me up pretty good.  I spent the next 2 hours trying to find out if the pills could be cut in half or crushed.  Finally called the number at Viekira.com.  The medical professional they connected me to said they had no clinical data to support either one.  Didn't say no, just they did not know. Trying to salvage the treatment, I cut one in half and tried to swallow again.  Both got stuck in the same place, but did not stop me from breathing.  It took a minute for them to slowly move down.  Needless to say, this stopped me from taking the rest of the morning treatment because if I can't take the bigger ones, I will have to stop treatment.  My next step is to see a gastroenterologist for an upper scope to see if there is an obstruction of some sort.  I am able to swallow soft objects and food.  This has me so disappointed.  Has anyone else out there had this problem and how did you deal with it?

   

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,546
  • Get tested, get treated, get cured, fight Hep c!
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,546
  • Get tested, get treated, get cured, fight Hep c!
Re: Trouble Swallowing Large Viekira Pak Pill
« Reply #2 on: January 11, 2016, 10:15:57 pm »
I also look at the prescribing information for Viekira and didn't see anything about cutting the big pink pills (ombitasvir/paritaprevir/ritonavir and dasabuvir)

But on the prescribing information sheet for Holkira Pak (which is Viekira in Canada) I did see:

"HOLKIRA™ PAK tablets should be swallowed whole, with water if required, and not chewed, broken, or crushed. To maximize absorption, HOLKIRA™ PAK should be taken with food without regard to fat or calorie content"

http://www.abbvie.ca/content/dam/abbviecorp/ca/english/docs/HOLKIRA_PAK_PM_EN.pdf

So I don't think cutting the pills is an option
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline HazelAustralia

  • Member
  • Posts: 178
Re: Trouble Swallowing Large Viekira Pak Pill
« Reply #3 on: January 12, 2016, 03:40:34 am »
Yes same here Lynn,

On the Australian supply there are instructions for taking the pink tablets (paritaprevir/ritonavir/rombitasvir) along with the beige one (dasabuvir) WHOLE -

"Do not chew, crush or break the tablets"

Sometimes relaxations exercises are used for young people who find it difficult to swallow pills. Have you had the problem previously Lorangerboy?

H.
Female age 53
Australia
Contracted in the 1980's
Genotype 1A
VL 314k

Started treatment with Veikira Pak and Ribaviron on Thursday 17th December 2015
NOT DETECTED, End of Treatment, 16th March 2016

Offline dragonslayerinprogress

  • Member
  • Posts: 62
Re: Trouble Swallowing Large Viekira Pak Pill
« Reply #4 on: January 25, 2016, 03:06:30 pm »
I have to break up my solvadi. Dr. said it was ok as well as pharmacist because they are not time teleased. Called Gilead too and they said what you heard, no public data. They did in house research but didn't complete it so they couldn't say yes or no. I would have not done treatment if I didn't cut them. Hoping to get lab work done to see if it still works :)
Geno 2b
dx in 1990, 52 years old
Origin: unsure. Might have been infected at birth
Tx Naive
Pre tx labs 12/7/15
VL 1,315,890 6.119
ALT 188
AST 161
Started tx Solvadi/Ribavirin on 1/19/16
4 weeks undetected
8 weeks undetected
12 weeks undetected
16 weeks undetected
20 weeks undetected
24 weeks...no testing
EOT 4 wks UNDETECTED
ALT 34
AST 42
EOT 8 wks- UNDETECTED
ALT 38
AST 50
Platelets 49

Offline AussieRosa

  • Member
  • Posts: 226
Re: Trouble Swallowing Large Viekira Pak Pill
« Reply #5 on: January 25, 2016, 08:46:00 pm »
Are you sure you're drinking enough water when you try to swallow the pill? If you're taking a couple of big gulps and it's still not going down it does sound as if there may be some kind of obstruction. Have you ever taken large multivitamin pills? They're of a comparable size.
Gt 1a
contracted 1983
Fibroscan 6.1
Treatment naive
VL 2.97M
ALT 38
AST 47
Started Viekira Pak + Ribavirin Tues 19th Jan 2016
Week 4: VL Undetected!
March 5th Ribavirin dose reduction to 800mg from 1000mg
EOT April 11th 2016. VL Not Detected
12 Weeks post EOT: SVR12. Cured with a capital C!!
6 months post EOT: Undetected :-)

 


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