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Author Topic: Ribavirin Savaldi 24 weeks  (Read 11718 times)

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Offline dan98584

  • Member
  • Posts: 21
Ribavirin Savaldi 24 weeks
« on: March 19, 2016, 10:45:22 pm »
Well after dangling on the end of other threads for a while , will start my own. Will be 7weeks into treatment on Monday. First bad news  my general MD called me yesterday to say I was slightly anemic and wanted to talk to me :-(
Logged
Male 60
Contacted hepatitis C genotype 3 1972-73?
on 24 weeks therapy of Ribavirin and Savaldi
Began treatment 2/1/16

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Ribavirin Savaldi 24 weeks
« Reply #1 on: March 19, 2016, 10:58:03 pm »
Hi Dan, and congrats on being 7 weeks into treatment! The anemia is to be expected with the ribavirin. If it becomes really serious, I am sure your doctor will reduce your ribavirin dose. Otherwise we just drag our anemic butts through to the end and then recover post-treatment.

best,
kim
Logged
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline AussieRosa

  • Member
  • Posts: 226
Re: Ribavirin Savaldi 24 weeks
« Reply #2 on: March 20, 2016, 02:55:24 am »
Hi, Dan. My hgb dropped 15% in the first few weeks on Riba. It stayed that way for a little while then went back up to nearly normal on it's own. Just letting you know that it might not necessarily get any worse. All the best.
Logged
Gt 1a
contracted 1983
Fibroscan 6.1
Treatment naive
VL 2.97M
ALT 38
AST 47
Started Viekira Pak + Ribavirin Tues 19th Jan 2016
Week 4: VL Undetected!
March 5th Ribavirin dose reduction to 800mg from 1000mg
EOT April 11th 2016. VL Not Detected
12 Weeks post EOT: SVR12. Cured with a capital C!!
6 months post EOT: Undetected :-)

Offline Philadelphia

  • Global Moderator
  • Member
  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: Ribavirin Savaldi 24 weeks
« Reply #3 on: March 20, 2016, 03:15:01 am »
Positive notes: you've already done 7 weeks, you're only slightly anaemic, you're still upright warm and breathing.

My haemoglobin dropped from150 to 100 in the first month. I was riba reduced from week onwards.

You've got to be pretty darned anaemic to be taken off.

Good luck!
Logged
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Gaj

  • Member
  • Posts: 172
  • Optimist
Re: Ribavirin Savaldi 24 weeks
« Reply #4 on: March 20, 2016, 08:49:04 am »
Hi Dan, as others say usually the drop in hgb is worst in the first few weeks so at 7 weeks you are probably okay. My general MD also got worried by my results initially but quickly read more on Riba effects while I was there and then didn't feel need to consult specialist. But he was able have to give some simple suggestions to help me with managing symptoms and recognising what to look out for and when I may need to seek advice.
Logged
Male - 61 years
Genotype 3a (since 1978?)
Diagnosed 2012
Treated 2013 PEG/Riba/Dac (Relapsed)
F4 - HCC#1 Resected 06/15 - #2 RFAblated 11/15
11/18/15 Commenced Generic Tx - Sof/Dac/Riba (24wks)
Pre Tx = ALT: 270  AST: 209  ALB: 31
05/05/16 = ALT: 34  AST: 32  ALB: 40  VL: Undetected (EOT)
06/16/16 = Relapsed
06/23/16 = ALT: 92  AST: 59  ALB: 40  VL: 290,770
01/12/17 3rd Tx - Zepatier + Sofosbuvir (16wks)
05/03/17 EOT und
06/22/17 SVR7 und
07/27/17 SVR12 UND!
10/26/17 SVR24 UND & Cured!!!

Offline dan98584

  • Member
  • Posts: 21
Re: Ribavirin Savaldi 24 weeks
« Reply #5 on: March 20, 2016, 10:19:51 pm »
thx for the encouragement. Hopefully no issue. Having surgery on Thursday. Gall bladder removal and a small hernia repair. So will be laid up for a bit 
Logged
Male 60
Contacted hepatitis C genotype 3 1972-73?
on 24 weeks therapy of Ribavirin and Savaldi
Began treatment 2/1/16

Offline dan98584

  • Member
  • Posts: 21
Re: Ribavirin Savaldi 24 weeks
« Reply #6 on: April 20, 2016, 08:02:10 pm »
Starting week 12 Monday. Insurance suddenly decides they need new authorization and documentation, playing phone tag for a week with them. meanwhile sitting here with enough pills to last thru Sunday night.  Grrr
Logged
Male 60
Contacted hepatitis C genotype 3 1972-73?
on 24 weeks therapy of Ribavirin and Savaldi
Began treatment 2/1/16

Offline dan98584

  • Member
  • Posts: 21
Re: Ribavirin Savaldi 24 weeks
« Reply #7 on: April 23, 2016, 04:54:16 pm »
pills arrived just in time gonna drop a note to my hep C doc and her medical assistant for helping me once more getting the Insurance peeps doing what they are supposed to do. Onward to week 13 of 24.
Logged
Male 60
Contacted hepatitis C genotype 3 1972-73?
on 24 weeks therapy of Ribavirin and Savaldi
Began treatment 2/1/16

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Ribavirin Savaldi 24 weeks
« Reply #8 on: April 24, 2016, 12:49:41 pm »
Glad that worked out, Dan! One stressor gone. Good luck with 2nd half of treatment.

kim
Logged
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline dan98584

  • Member
  • Posts: 21
Re: Ribavirin Savaldi 24 weeks
« Reply #9 on: July 26, 2016, 09:22:48 pm »
24 week treatment complete. No viral load detected. However blood count is abnormal this time. probable side effect from meds retest that in 4 weeks. Hip hip Hooray
Logged
Male 60
Contacted hepatitis C genotype 3 1972-73?
on 24 weeks therapy of Ribavirin and Savaldi
Began treatment 2/1/16

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Ribavirin Savaldi 24 weeks
« Reply #10 on: July 26, 2016, 09:34:29 pm »
Quote from: dan98584 on July 26, 2016, 09:22:48 pm
24 week treatment complete. No viral load detected. However blood count is abnormal this time. probable side effect from meds retest that in 4 weeks. Hip hip Hooray

CONGRATS DAN !! Well done!

If your blood abnormality is just low hemoglobin and red blood cells from the ribavirin, I think most people find that returns to normal in 4 weeks or so. Mine didn't, but yours probably will.

Now go celebrate!
kim :)
Logged
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Philadelphia

  • Global Moderator
  • Member
  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: Ribavirin Savaldi 24 weeks
« Reply #11 on: July 27, 2016, 06:45:38 am »
Congrats on the SVR and I echo what Kim said. Let's us know how you get on.
Logged
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline dan98584

  • Member
  • Posts: 21
Re: Ribavirin Savaldi 24 weeks
« Reply #12 on: November 02, 2016, 01:45:02 am »
Congratulations Daniel...your final lab check shows continued undetectable Hepatitis C virus. No further testing is warranted at this point and time. Remember that you will always test positive for the Hepatitis C antibody and if there is ever a question about active virus, a viral load (test) is the way to confirm eradication.
Logged
Male 60
Contacted hepatitis C genotype 3 1972-73?
on 24 weeks therapy of Ribavirin and Savaldi
Began treatment 2/1/16
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