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Author Topic: svr 24 do I need another one ?  (Read 8602 times)

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Offline jakas

  • Member
  • Posts: 265
svr 24 do I need another one ?
« on: March 19, 2017, 06:27:02 am »
I got the SVR 24 last year August. Its been over a year since I stopped Harvoni do you guys think I should take another test to get SVR 52. I feel ok expect for the odd stuff that comes with age.
Logged
M/57 yrs.
Contracted (Unknown) 10-20-30 yrs back ??
Treatment Naive
Geno 1a&1b
VL  17+ million
ALT 200+, AST 170+
Fibroscan F4 ( 26+ kpa ) on 8th Dec. 2105
Started Tx 11th Dec.2015 ( 12 wks. Gilead Harvoni)
7/1/2016 :Viral Load|<25 UND.
23/1/2016: ALT 34 , AST 35, ALP 143
8 week NO labs done
EOT:03.03.2016 ( 84 pills eaten )
ALT 26, ALP 124, BIL .54
V/L <25 UND E.O.T.
4 weeks E.O.T. V/L UND::: SVR 4
SVR 12 and  SVR 24 on 16/8/16
Fibro 24.5kpa 23/05/16
SVR 63 05/17
Fibro 17.03.2020 kpa 6.3

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: svr 24 do I need another one ?
« Reply #1 on: March 19, 2017, 08:41:33 am »
Congrats on the SVR24. Does your doc want you to have another one? My hepatologist not only wanted a VL at the one-year mark, he wants one at the two-year mark and another at the three-year mark, even though my fibrosis level has gone down from F4 to borderline F2/F3 and he expects it to go down to F2. I don't know whether those extra VL tests are really needed or if he just wants data to feed his research interests.
Logged
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline jakas

  • Member
  • Posts: 265
Re: svr 24 do I need another one ?
« Reply #2 on: March 19, 2017, 09:27:38 am »
No. The doc was happy with svr 12 but I insisted on another test for SVR 24. I will have to get it done in private. The state wont pay but thats not an issue
Logged
M/57 yrs.
Contracted (Unknown) 10-20-30 yrs back ??
Treatment Naive
Geno 1a&1b
VL  17+ million
ALT 200+, AST 170+
Fibroscan F4 ( 26+ kpa ) on 8th Dec. 2105
Started Tx 11th Dec.2015 ( 12 wks. Gilead Harvoni)
7/1/2016 :Viral Load|<25 UND.
23/1/2016: ALT 34 , AST 35, ALP 143
8 week NO labs done
EOT:03.03.2016 ( 84 pills eaten )
ALT 26, ALP 124, BIL .54
V/L <25 UND E.O.T.
4 weeks E.O.T. V/L UND::: SVR 4
SVR 12 and  SVR 24 on 16/8/16
Fibro 24.5kpa 23/05/16
SVR 63 05/17
Fibro 17.03.2020 kpa 6.3

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,546
  • Get tested, get treated, get cured, fight Hep c!
Re: svr 24 do I need another one ?
« Reply #3 on: March 21, 2017, 05:16:20 am »
Heck even with my history of 4 failed treatments and F$ cirrhosis I was satisfied at 1 year that I was SVR. If I hadn't been for my history I would be fine with SVR24.

And anyway if you did ever relapse or become reinfected it would show up in your liver function tests.

I notice you have cirrhosis. Are you having blood testing done every 6 months including an AFP blood test and abdominal ultrasound to check for early signs of HCC? I am assuming you are being followed by a hepatologist of at least a gastroenterologist associated with a liver transplant center.
Logged
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline jakas

  • Member
  • Posts: 265
Re: svr 24 do I need another one ?
« Reply #4 on: March 21, 2017, 09:45:32 am »
Well those tests should be done atleast the ultrasound but no news as yet. Its just been 1 year since stopped medication.
They did an MRI 3 MONTHS BACK. Nothing to worry about they said.
Thanks Lynn will do an LFT ( LIVER FUNCTION TEST ) next weekend.
I HAVE LOT OF DENTAL work done yearly, thats once place I can get reinfected  IF I ever do get reinfected.
Logged
M/57 yrs.
Contracted (Unknown) 10-20-30 yrs back ??
Treatment Naive
Geno 1a&1b
VL  17+ million
ALT 200+, AST 170+
Fibroscan F4 ( 26+ kpa ) on 8th Dec. 2105
Started Tx 11th Dec.2015 ( 12 wks. Gilead Harvoni)
7/1/2016 :Viral Load|<25 UND.
23/1/2016: ALT 34 , AST 35, ALP 143
8 week NO labs done
EOT:03.03.2016 ( 84 pills eaten )
ALT 26, ALP 124, BIL .54
V/L <25 UND E.O.T.
4 weeks E.O.T. V/L UND::: SVR 4
SVR 12 and  SVR 24 on 16/8/16
Fibro 24.5kpa 23/05/16
SVR 63 05/17
Fibro 17.03.2020 kpa 6.3

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,546
  • Get tested, get treated, get cured, fight Hep c!
Re: svr 24 do I need another one ?
« Reply #5 on: March 21, 2017, 03:53:51 pm »
Yes any medical procedure does carry risk of infection with many things including hep c. However any licensed medical facility should be using universal precautions to help minimize the risk and this type of infection is rare thankfully.

Just don't get a back alley tattoo and you should be fine :)
Logged
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline jakas

  • Member
  • Posts: 265
Re: svr 24 do I need another one ?
« Reply #6 on: March 22, 2017, 09:57:42 am »
No tatoos for me. Never got any, now I feel I am too old for them :D :D
Logged
M/57 yrs.
Contracted (Unknown) 10-20-30 yrs back ??
Treatment Naive
Geno 1a&1b
VL  17+ million
ALT 200+, AST 170+
Fibroscan F4 ( 26+ kpa ) on 8th Dec. 2105
Started Tx 11th Dec.2015 ( 12 wks. Gilead Harvoni)
7/1/2016 :Viral Load|<25 UND.
23/1/2016: ALT 34 , AST 35, ALP 143
8 week NO labs done
EOT:03.03.2016 ( 84 pills eaten )
ALT 26, ALP 124, BIL .54
V/L <25 UND E.O.T.
4 weeks E.O.T. V/L UND::: SVR 4
SVR 12 and  SVR 24 on 16/8/16
Fibro 24.5kpa 23/05/16
SVR 63 05/17
Fibro 17.03.2020 kpa 6.3

Offline FutureThinker

  • Member
  • Posts: 711
  • Onward and upward!
Re: svr 24 do I need another one ?
« Reply #7 on: March 22, 2017, 12:21:47 pm »
Hey Jakas, on my last (!) hepatologist appointment last month, which was well past SVR 24, she requested that my PCP do one more VL test in a year.  My assumption was that this was for research or knowledge reasons due to the continued body of info coming in on these DAAs.  So I'm going to comply.  Seems each doctor is asking for different things; mine is at a large university medical center, don't know if that's got anything to do w/ her request or not.  FT
Logged
Treatment naive
Likely contracted mid-70s
Diagnosed 1a, 2011
F1-2
Harvoni X 12 weeks, completed 5/17/16
Pre-treatment: VL 3 mil, AST 64, ALT 84
4 week labs: VL 30, AST 21, ALT 14
8 week labs: VL UD!!!, AST 22, ALT 16
12 week labs: VL UD, AST 23, ALT 14
2 wk EOT: VL UD
12 wk EOT: VL UD, AST 22, ALT 13 =  SVR 12! Yay! 
Last hep appointment: VL UD, AST 19, ALT 12 = SVR 39! I AM DONE!
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