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Author Topic: Fibrospedt ll index score vs. biopsy stages  (Read 7135 times)

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Offline trapper

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  • Posts: 56
Fibrospedt ll index score vs. biopsy stages
« on: July 05, 2014, 01:24:32 pm »
One of UHC criteria for sov/Olysio treatment is .  Submission of medical records documenting stage 3 or 4 hepatic fibrosis including one of the following.  1. Liver biopsy confirming a metavir score of f3 or f or alternative scoring equivalent or b.  transient elastography (Fibroscan) score greater than or equal to 9.5 kPa. or c.  FibroTest (FibroSURE) score greater than or equal to 0.58. or D.  APRI score greater than 1.5. or e.  Radiological imaging consistent with cirrhosis ( e.g., evidence of portal hypertension.  or f.  Physical findings or clinical evidence consistent with cirrhosis as attested by the prescribing physician.
   I had a Fibrospect ll test done.  My result was F2-F4 with a index score of 8 6.  I have a chart (Fibrosis Stages and FIBROSpect ll Index) that says that a score of 80-100 with 39 Patients , 22 showed f4, 13 showed f3, 3 showed f2.  Test correlation was highest with Batts-Ludwig stages 3 (77%) and 4 (96%) and the lowest with f2 (43%).  Are any of the tests above related to or same as the fibrospect ll test.  My doctor scheduled me for a liver biopsy soon.  Do I really need a biopsy and if I do,  do you need a single biopsy or multiple areas of the liver.  Thanks   Trapper

Offline Mike

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  • Posts: 999
Re: Fibrospedt ll index score vs. biopsy stages
« Reply #1 on: July 05, 2014, 02:49:29 pm »
Hi Trapper,

I've heard the scan results are fairly accurate; but currently, a biopsy is the gold standard for diagnosing cirrhosis and inflammation and should confirm or clarify the scan results. I had a biopsy in 2001, and although not fun, if my GI indicated I need another one, I wouldn't hesitate doing so.

The biopsy allows for an actual few of the liver cells under a microscope and is conclusive. Generally, a single sample is all that is needed, as Hep-C, unlike cancer, damages the entire liver - not just the area that a malignant tumor might effect.

Best wishes, Mike
Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014

 


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