Welcome, Guest. Please login or register.
April 18, 2024, 07:43:09 pm

Login with username, password and session length


Members
  • Total Members: 6307
  • Latest: golfer
Stats
  • Total Posts: 55125
  • Total Topics: 4851
  • Online Today: 77
  • Online Ever: 1314
  • (June 22, 2016, 05:23:42 am)
Users Online
Users: 0
Guests: 60
Total: 60

Welcome

Welcome to the Hep Forums, a round-the-clock discussion area for people who have Fatty Liver Disease, Hepatitis B, C or a co-infection, their friends and family and others with questions about hepatitis and liver health. Check in frequently to read what others have to say, post your comments, and hopefully learn more about how you can reach your own health goals.

Privacy Warning: Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.
  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.
  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.
  • Product advertisement (including links); banners; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from the Hep Forum Moderators.
Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: stages and genotypes?  (Read 13180 times)

0 Members and 1 Guest are viewing this topic.

Offline stillcasey

  • Member
  • Posts: 8
stages and genotypes?
« on: July 06, 2014, 09:42:38 pm »
I find myself drowning trying to find out about this. What are the stages and genotypes? What do they mean and how do you find out? How does the treatment differ? Thanks for any insight into this.

Offline willie g

  • Member
  • Posts: 427
  • geno 1 25million etc. s/o for treatment
Re: stages and genotypes?
« Reply #1 on: July 10, 2014, 07:19:29 pm »
HI, I TOO WAS WONDERING ALL ABOUT THE SAME THING NOT TO LONG AGO.THIS FORUM IS GREAT AND YOU WILL BE ABLE TO PIECE THINGS TOGETHER FROM ALL THE STORIES AND COMMENTS AND I HIGHLY RECOMEND YOU GET LUCINDA PORTERS BOOKS. SHE IS THE MODERATOR AND TRUST ME FOR THE SMALL PURCHASE YOU WILL LEARN EVERYTHING YOU NEED AND WANT TO KNOW ABOUT YOUR QUESTIONS AS WELL AS SO MUCH MORE. I DOWNLOADED HER BOOKS FROM MY KINDLE WHICH MADE IT EASY BUT WHATEVER METHOD YOU USE TO GET BOOKS ,GO FOR IT. SHE HAS HAD TO GO THRU TREATMENT 3 TIMES! WHAT A STORY AND WHAT KNOWLEDGE FROM ONE OF US.THE REAL DEAL. GOOD LUCK AND SOON YOU WILL KNOW SO MUCH THAT SOMETIMES OVERWHELMS YOU, BUT DONT GET DISCOURAGED BECAUSE YOUR IN THE RIGHT PLACE.  WILLIE G

Offline Mike

  • Member
  • Posts: 999
Re: stages and genotypes?
« Reply #2 on: July 10, 2014, 07:26:22 pm »
Hep-C virus has 6 genotype: 1, 2, 3, 4, 5, & 6. These are called genotype groups. Within each group, there are known subgroups. For example, within the genotype 1 group, there is genotype 1a and 1b.  Here is a list of known genotype groups, with their identified subgroups:

Genotype 1a & 1b
Genotype 2a, 2b, 2c & 2d
Genotype 3a, 3b, 3c, 3d, 3e & 3f
Genotype 4a, 4b, 4c, 4d, 4e, 4f, 4g, 4h, 4i & 4j
Genotype 5a
Genotype 6a

This is important because individual genotype groups respond differently to antiviral drugs/treatment. This is true with genotype subgroups.

Simply put, what may be a very effective treatment for genotype 2a - may not be as effective on, let's say, genotype 4e.

Knowing your genotype helps the doctor identify the most effective treatment protocol for you. The presence and extent of liver damage is also a consideration in making treatment decisions, as is your tolerance of certain drugs used in treatment.

In addition, you may have noticed that not everyone is completing the same treatment protocol. Some are on a 12 week course; whilst others are on a 24 week course. Some folks are completing a 3-drug protocol; others are only completing a two drug protocol.

This is why genotype, extent of liver damage and other factors are so important: All treatment decisions are guided by these factors.

Best wishes, Mike
Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014

Offline willie g

  • Member
  • Posts: 427
  • geno 1 25million etc. s/o for treatment
Re: stages and genotypes?
« Reply #3 on: July 10, 2014, 07:36:25 pm »
SEE , YOUR QUESTIONS ARE ALREADY BEING ADRESED[MY SPELLING STINKS]   YOU ARE IN THE RIGHT PLACE!  THX MIKE GOOD JOB AND I LEARNED SOMETHING I DIDNT KNOW BEFORE OR I DIDNT GRASP.  WILLIE G

Offline lporterrn

  • Member
  • Posts: 1,969
  • LucindaPorterRN
    • LucindaPorterRN
Re: stages and genotypes?
« Reply #4 on: July 11, 2014, 02:18:19 pm »
Stillcasey - If you are drowning trying to find info, then what I am about to say will make things worse - they just reclassified genotype info - there are now 7 genotypes and 67 subtypes. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063340/

Here is a suggestion: ask your doc what your genotype is, or to run a genotype test, and then ask what treatment he/she recommends - then you only have to wade through the info that is pertinent to you. We can help with that.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline Mike

  • Member
  • Posts: 999
Re: stages and genotypes?
« Reply #5 on: July 11, 2014, 02:37:49 pm »
Thanks for posting this, Lucinda.

I didn't realize there were so many subtypes, Mike
Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014

 


© 2024 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.