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Author Topic: Hep C Decays Faster in Blood Than in the Liver During Treatment  (Read 6689 times)

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Offline iana5252

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The first study to track in real time the decay of hepatitis C virus (HCV) has found that the virus breaks down more quickly in the blood than in the liver—findings that have implications for determining the proper length of treatment. Publishing their study results in Hepatology, researchers used fine-needle aspiration to sample the livers of 15 participants with hep C at various times during their treatment with Incivek (telaprevir).

The investigators measured viral kinetics, drug resistance patterns, drug concentrations and host transcription profiles. They found that viral decay in the liver occurred more slowly than in the blood, and that Incivek levels were also higher in the blood than in the liver.

Read more...
http://www.hepmag.com/articles/viral_decay_2501_25850.shtml

 


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