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Author Topic: Completed 12 weeks Harvoni  (Read 22152 times)

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Offline luckysincere

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Completed 12 weeks Harvoni
« on: January 16, 2015, 06:47:11 pm »
I took my last pill yesterday and my 12 week labs as well.  I have also been on Ribavirin for the last 5 weeks of Harvoni.  vl was 1.5 million (no cirrhosis) when I started treatment in October (treatment naive as I was just diagnosed in April 2014).  My 4 week vl was <15, as was my 8 week.  My dr was confused and concerned as to why the virus was still detectable. She started the ribavirin even though the study showed no advantage because she wanted to give me the best chance possible in beating this.  I didn't experience many side affects from either.  A few headaches in the beginning of both and a little fatigue lately.  Now it feels strange to not take anything and just to be waiting for the results!  I am still uncertain where I contracted the virus, but we think I was possibly exposed to Hep A in April and it awakened the sleeping C.  Perhaps a nose straw long ago in another life......I'm not going to question that because it really doesn't matter.  Sorry to go for so long. I just felt like sharing my Harvoni experience because I know so many are researching it's affects.  I should have my test results early next week and will share them.  Good luck to all who are fighting this!

Offline lporterrn

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  • LucindaPorterRN
    • LucindaPorterRN
Re: Completed 12 weeks Harvoni
« Reply #1 on: January 16, 2015, 11:26:13 pm »
Congratulations on reaching this milestone. An unusual journey, but you made it. Thanks for sharing. Let us know your results when you know them.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline JillLynn

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  • Posts: 205
  • contracted 1973/ peg/rib 1999 & 2004/on harvoni
Re: Completed 12 weeks Harvoni
« Reply #2 on: January 18, 2015, 10:25:01 am »
I finished 12 weeks of Harvoni also and am waiting my last viral load test also.
  All other tests are in and everything looks good.

Offline badbradley

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  • Posts: 294
Re: Completed 12 weeks Harvoni
« Reply #3 on: January 18, 2015, 10:31:27 am »
Hi Jill,
     Good to see you back! Good luck on your VL test. The normal enzyme levels are a good sign. Best wishes.
Brad
Geno 1a
Sov/Oly 12wks - relapse
Har/Riba 12wks
Alt-16  Ast-17 SVR - 12
Alt-15  Ast-14 SVR - 24

Offline badbradley

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  • Posts: 294
Re: Completed 12 weeks Harvoni
« Reply #4 on: January 18, 2015, 10:41:40 am »
Hey Mel and Sunrise,
     Good Sunday morning. Today is the big game! Packers vs. Seahawks. I am a huge packers fan. Heading out for game food shortly. The stores are usually congested  before the game and today is the NFC championship! Game is at 2:00 central time. Anyone else watching? GO PACK GO!!!!   Superbowl here we come!   Talk later. Hope everyone is doing well.
Brad
Geno 1a
Sov/Oly 12wks - relapse
Har/Riba 12wks
Alt-16  Ast-17 SVR - 12
Alt-15  Ast-14 SVR - 24

Offline JillLynn

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  • Posts: 205
  • contracted 1973/ peg/rib 1999 & 2004/on harvoni
Re: Completed 12 weeks Harvoni
« Reply #5 on: January 18, 2015, 10:50:58 am »
Good Morning Brad! and thank you!  :) 
 Hi!   Well...since my beloved Detroit Lions got robbed.......I'm rooting for the Packers as well!!     

good morning Mel and Sunrise too!     

Cheers!    Jyl

Offline lporterrn

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  • LucindaPorterRN
    • LucindaPorterRN
Re: Completed 12 weeks Harvoni
« Reply #6 on: January 18, 2015, 12:53:10 pm »
Congratulations JillLynn. So now we wait with you.

Brad - I have to tread carefully so not to offend any Seattle fans, but I can safely say that most 49ers fans (of which I am one) would love to see the Packers go to the SB. Hope you are celebrating at the end of the day.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline sunrise

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  • Posts: 463
Re: Completed 12 weeks Harvoni
« Reply #7 on: January 18, 2015, 03:20:02 pm »
Hey Brad
I'm recording the game lol. Just alittle time lapse . Jill best of luck on results. I wait with you also. We are all waiting for some major thresholds to get thru.I already got some pizza. Cleaned the shop now I sit home alone and watch the game. May the best team win :)

Offline Lynn K

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  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: Completed 12 weeks Harvoni
« Reply #8 on: January 18, 2015, 09:27:56 pm »
Hi all from Seattle

To all Packers fans present I want to thank you for a great comptition it was a heck on an exciting game. I wish you a great 2015- 2016 season but this year is ours! Hope you can root for us in the Super Bowl.

Go Hawks!
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline lporterrn

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  • LucindaPorterRN
    • LucindaPorterRN
Re: Completed 12 weeks Harvoni
« Reply #9 on: January 18, 2015, 10:50:23 pm »
How about we root for you in the Hepatitis C Negative Bowl Lynn K! (Congratulations)
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline Lynn K

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  • Member
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  • Get tested, get treated, get cured, fight Hep c!
Re: Completed 12 weeks Harvoni
« Reply #10 on: January 18, 2015, 10:55:28 pm »
I can accept that. :-)

And the same for us all!

Go team Dragonslayers!
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline PaulG

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  • Posts: 38
Re: Completed 12 weeks Harvoni
« Reply #11 on: January 18, 2015, 11:36:45 pm »
What a game Seattle played stay strong and you can do anything

Offline sunrise

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  • Posts: 463
Re: Completed 12 weeks Harvoni
« Reply #12 on: January 19, 2015, 04:07:46 pm »
So true Paul
       Tomorrow is my 4 week post tx. bloodwork. Hey Jill best of luck on yours. Brad you are in 2 weeks for your 12 week. Best wishes everyone. How your side effects Brad? Are they subsiding? Sunrise

Offline badbradley

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  • Posts: 294
Re: Completed 12 weeks Harvoni
« Reply #13 on: January 19, 2015, 05:00:40 pm »
Sunrise
 
  Oh,  The Agony Of Deafeat!!!   :o :'(

That is my only side effect right now.

Actually, I am feeling very well. I did not have too many problems before treatment other than digestive issues. IBS they say. That has gotten considerably better. I had some eye issues that would cause severe headaches for 2-3 days at a time. I have not had any eye/headache issues since halfway through treatment. It's nice!
I  did have the normal treatment side effects but nothing lasting.
   Yes my SVR12 test is Two weeks from tomorrow. Here we are at the crossroads I'm pullin' for ya! Positive your negative!
                                      Brad
Geno 1a
Sov/Oly 12wks - relapse
Har/Riba 12wks
Alt-16  Ast-17 SVR - 12
Alt-15  Ast-14 SVR - 24

Offline sunrise

  • Member
  • Posts: 463
Re: Completed 12 weeks Harvoni
« Reply #14 on: January 19, 2015, 05:11:08 pm »
Lol its hard to say defeat Brad. I lived in Seattle for 12 yrs before i came to the south wes, so I have to go for the hawks! Dont hate me. Anyway its good to hear you are feeling better. It wierd how this virus affects everyone so differently. As well as the tx. Thanks for the pep talk. Sounds like you beat it! I pray I did as well.. Blessings Sunrise

Offline sunrise

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  • Posts: 463
Re: Completed 12 weeks Harvoni
« Reply #15 on: January 19, 2015, 05:12:43 pm »
Lol its hard to say defeat Brad. I lived in Seattle for 12 yrs before i came to the south wes, so I have to go for the hawks! Dont hate me. Anyway its good to hear you are feeling better. It wierd how this virus affects everyone so differently. As well as the tx. Thanks for the pep talk. Sounds like you beat it! I pray I did as well.. Blessings Sunrise

Offline sunrise

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  • Posts: 463
Re: Completed 12 weeks Harvoni
« Reply #16 on: January 19, 2015, 05:14:49 pm »
Sorry technical error >:(

Offline badbradley

  • Member
  • Posts: 294
Re: Completed 12 weeks Harvoni
« Reply #17 on: January 19, 2015, 05:29:27 pm »
Sunrise
  Hawks ???
        I don't know if we can be on the same thread together anymore!  lol
Geno 1a
Sov/Oly 12wks - relapse
Har/Riba 12wks
Alt-16  Ast-17 SVR - 12
Alt-15  Ast-14 SVR - 24

Offline sunrise

  • Member
  • Posts: 463
Re: Completed 12 weeks Harvoni
« Reply #18 on: January 19, 2015, 05:43:53 pm »
Noooooo  ;).From now on I will stick to the subject on hand. Negative tests results!!  ;D

Offline badbradley

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  • Posts: 294
Re: Completed 12 weeks Harvoni
« Reply #19 on: January 19, 2015, 05:50:19 pm »
I'll need some time on this one.

O.K. You got a deal!
Geno 1a
Sov/Oly 12wks - relapse
Har/Riba 12wks
Alt-16  Ast-17 SVR - 12
Alt-15  Ast-14 SVR - 24

Offline luckysincere

  • Member
  • Posts: 7
Re: Completed 12 weeks Harvoni
« Reply #20 on: January 21, 2015, 07:22:26 pm »
Got my results on Monday and I am undetectable.  Yesterday was my birthday in more ways than one!

Good luck to all!

Offline sunrise

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  • Posts: 463
Re: Completed 12 weeks Harvoni
« Reply #21 on: January 21, 2015, 10:21:49 pm »
Thats great news luckysincere!
          Happy UD day a belated Happy Birthday as well :-)
 So undetected at EOT, Same here, that so great. Just took labs yesterday so next week for results. Keep up the fight lucky...Blessings Sunrise

Offline Lynn K

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  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: Completed 12 weeks Harvoni
« Reply #22 on: January 21, 2015, 10:45:00 pm »
Congrats Lucky

Now just the 12 week post treatment test to make sure you have acheived SVR
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Paleface

  • Member
  • Posts: 35
Re: Completed 12 weeks Harvoni
« Reply #23 on: January 22, 2015, 10:13:28 am »
Hi Lucky,
CONGRATULATIONS!!
Im not sure why your doc was concerned. If your 4 and 8 week test was <15 that is undetectable. The test results show <15 because they cant detect lesser amounts of the virus. At least thats what I read :-)  You are going to be fine.
Keith
Hep C 1a
Blood Transfusion- 1977
2002-48 wks Peg Interferon+Ribavirin-relapsed 2003.
VL- 5,700,620
AST- 393
ALT- 717
Liver Biopsy- Stage 1-2
Oct.29,2014- 12 wks Harvoni
Jan.20,2015 Finished Harvoni Treatment-Undetectable
4 wk post- Undetected
8 wk post- Undetected
12 wk post- Undetected- "Cured"

Offline Lynn K

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  • Get tested, get treated, get cured, fight Hep c!
Re: Completed 12 weeks Harvoni
« Reply #24 on: January 23, 2015, 02:14:41 am »
Hi Paleface

My lab report has a note explaining the meaning

The quantitative range of the assay is 15 IU/mL to 100 million IU/mL
using COBAS(R) TaqMan(R) HCV test, v 2.0. The limit of detection (LOD)
and lower limit of quantification (LLOQ) for this assay is 15 IU/mL.
Results less than the quantitative range of the assay will be reported
as "HCV RNA detected, less than 15 IU/mL".

So <15 still means detected just below the level of the ability of the test to quantify(count) think quantity. It means there is still an indication of the presence of the virus. The virus is still detected.

This is what my most recent lab says:

HCV RNA RT-PCR, QT   HCV Not Detected

which means what is says the test cannot detect the presence of virus at all
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Paleface

  • Member
  • Posts: 35
Re: Completed 12 weeks Harvoni
« Reply #25 on: January 23, 2015, 10:07:30 pm »
Thanks for the clarification Lynne. I hope that is what mine says :-)
Hep C 1a
Blood Transfusion- 1977
2002-48 wks Peg Interferon+Ribavirin-relapsed 2003.
VL- 5,700,620
AST- 393
ALT- 717
Liver Biopsy- Stage 1-2
Oct.29,2014- 12 wks Harvoni
Jan.20,2015 Finished Harvoni Treatment-Undetectable
4 wk post- Undetected
8 wk post- Undetected
12 wk post- Undetected- "Cured"

Offline Johnny_Wayne

  • Member
  • Posts: 47
Re: Completed 12 weeks Harvoni
« Reply #26 on: January 27, 2015, 09:11:28 pm »
Harvoni 12 weeks tx (I am on my last 2 pills)
Blood test at week 9 = NO HCV RNA DETECTED
MELD score dropped from 14 to 9 (in the first 8 weeks)
AST / ALT = Normal
 
Diagnosed 04/2014
Started Harvoni 10/2014
Undetectable 01/2015
Relapsed 04/2015
F4 Cirrhosis (Compensated - barely)
Child Pugh Score 6-7
MELD Score 10
Started Olysio/Sovaldi/Ribavirin (24 weeks)
EOT Not Detected 11/9/2016
--------------------------------
5-10-2017
Virus undetected SVR 24 Achieved
I AM FINALLY CURED!

Offline Lynn K

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  • Get tested, get treated, get cured, fight Hep c!
Re: Completed 12 weeks Harvoni
« Reply #27 on: January 28, 2015, 05:08:42 am »
No worries Keith

I am sure it will
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Lukey

  • Member
  • Posts: 319
  • Let Thy Food Be Thy Medicine
Re: Completed 12 weeks Harvoni
« Reply #28 on: January 28, 2015, 06:24:18 am »
Got my results on Monday and I am undetectable.  Yesterday was my birthday in more ways than one!

Good luck to all!

WTG luckysincere!!!

Best wishes for a forever SVR.
My signature will tell you where I'm at with Harvoni.

Joe

Male -  HCV since 1982 - Born 1951 ~ Geno 1a

Did 8 weeks of Harvoni in 2015. Got normal AST & ALT and undetected VL by week 5, then relapsed 4 weeks post.
-----------------------------------------------------------
July 5, 2018 : began 12 weeks of Vosevi with a VL of 540,000 and AST & ALT of 65 and 105.
2 weeks in : AST 19, ALT 20
5 weeks in : AST 18, ALT 12, VL "<15 detected"
10 weeks in : AST 19, ALT 14, VL "<15 not detected"
4 weeks post : "<15 not detected"

 


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