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Author Topic: HARVONI AND TYLENOL  (Read 10458 times)

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Offline Alfredo

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HARVONI AND TYLENOL
« on: February 27, 2015, 08:07:45 pm »
Can harvoni and tylenol be taken together?

Offline Ruthie

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Re: HARVONI AND TYLENOL
« Reply #1 on: February 27, 2015, 09:22:24 pm »
They sure can. Just be careful if you have cirrhosis.  And drink tons of water. 

Offline Lynn K

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  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Re: HARVONI AND TYLENOL
« Reply #2 on: February 27, 2015, 10:58:56 pm »
Tylenol is actually the preferred pain reliever with cirrhosis as long as no more than 2000 mg / day This is because people with cirrhosis have increased bleeding risk so cant take aspirin Advil Aleve etc
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Alfredo

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  • Posts: 10
Re: HARVONI AND TYLENOL
« Reply #3 on: March 04, 2015, 08:44:11 pm »
Lynn, is that because of the varices ?

Offline Lynn K

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Re: HARVONI AND TYLENOL
« Reply #4 on: March 05, 2015, 03:49:22 am »
Here is some info

http://www.aafp.org/afp/2009/1215/p1371.html

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used, but have risks associated with their use, including significant upper gastrointestinal tract bleeding. Older persons, persons taking anticoagulants, and persons with a history of upper gastrointestinal tract bleeding associated with NSAIDs are at especially high risk. Although aspirin is cardioprotective, other NSAIDs can worsen congestive heart failure, can increase blood pressure, and are related to adverse cardiovascular events, such as myocardial infarction and ischemia. Cyclooxygenase-2 inhibitors have been associated with increased risk of myocardial infarction; however, the only cyclooxygenase-2 inhibitor still available in the United States, celecoxib, seems to be safer in this regard. Hepatic damage from NSAIDs is rare, but these medications should not be used in persons with cirrhotic liver diseases because bleeding problems and renal failure are more likely. Care should be used when prescribing NSAIDs in persons taking anticoagulants and in those with platelet dysfunction, as well as immediately before surgery.

Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Re: HARVONI AND TYLENOL
« Reply #5 on: March 05, 2015, 03:52:10 am »
Also

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861975/pdf/mayoclinproc_85_5_008.pdf

Pain Management in the Cirrhotic Patient:
The Clinical Challenge

Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Alfredo

  • Member
  • Posts: 10
Re: HARVONI AND TYLENOL
« Reply #6 on: March 05, 2015, 06:01:00 pm »
Great article, thanks.

 


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