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Author Topic: long-term clinical cure  (Read 8280 times)

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Offline spitzbar

  • Member
  • Posts: 25
long-term clinical cure
« on: April 13, 2015, 10:29:37 am »

Offline dragonslayer

  • Member
  • Posts: 873
Re: long-term clinical cure
« Reply #1 on: April 13, 2015, 02:21:12 pm »
Spitzbar...

You always find the good articles!!  Thanks much for the link.
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline Bituman

  • Member
  • Posts: 157
Re: long-term clinical cure
« Reply #2 on: April 13, 2015, 10:51:52 pm »
Of the three that were not HCV RNA negative, I wonder where the "trace HCV RNA"  came from?  Is it possible this trace RNA is similar to those that end treatment still "detected" but at very low levels?  In any case, if a person attains SVR, then their long term outlook appears great. 

Bob
Age = 59, male, infected likely 1975
DX 07/07 GT 1a
Biopsy 2007:  GR 1, stage 0, HAI = 2/18
Since 2007:  1.48 MM < VL < 11 MM, avg = 5.64 MM
IL28B=CT
1/26/15, AST=43, ALT=55, VL=3.59 MM
2/5 Start Harvoni 12 weeks; Treat naive
2/20 AST=29, ALT=24, VL=59
3/6 AST=29, ALT=25, VL<15
3/19 AST=24, ALT=22, VL=undet
4/3 AST=29, ALT=25, VL=undet
4/30 EOT, AST=22, ALT=20, VL=undet
5/29 EOT+4, AST=20, ALT=19, VL=undet SVR
7/24 EOT+12, AST=23, ALT=18, VL=undet SVR
10/16 EOT+24, AST=22, ALT=17, VL=undet SVR

 


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