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Author Topic: Relapse? There's hope! Next-generation DAAs (You're gonna love this)  (Read 4778 times)

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Offline sickpuppy

  • Member
  • Posts: 51
Short story: 100% SVR rates in 6 weeks, with no resistance, and with a NS3/4A inhibitor component for those who failed any of the previous DAA treatments (Harvoni, Daklinza, Viekirax, etc.).

Link: http://www.achillion.com/ACH3422

Together, these three are the real deal.

Phase II is just commencing. Phase II pilot study is on-going. Interim results here:  http://ir.achillion.com/releasedetail.cfm?releaseid=881592

More reading: http://globenewswire.com/news-release/2015/04/25/728329/10130749/en/Achillion-Presents-Detailed-Clinical-Results-on-ACH-3102-and-ACH-3422-at-the-International-Liver-Congress.html

Some of the studies you will find are the combination of ACH3422 + sofosbuvir - however they are developing their own sofosbuvir and adding in a NS3/4A inhibitor for good measure.

I am hopeful.
GT1a - TX-naive

Baseline:

16.2 kPa
ALT: 61 iu/L
ALP: 74 iu/L
Albumin: 38g/L
Bilirubin: 27 umol/L
Platelets: 80
VL: 792,000
History of 4 violent varices bleeding episodes and splenomegaly present.

21/07/15 - TX start - Harvoni + Ribavirin 12 weeks.
Week 2 - UND
Week 4 - UND
Week 8 - UND
13/10/15 Week 12 - UND
19/11/15 - SVR4
8/1/16 - SVR12 !!!!!

Offline sunrise

  • Member
  • Posts: 463
Re: Relapse? There's hope! Next-generation DAAs (You're gonna love this)
« Reply #1 on: August 12, 2015, 09:20:31 am »
Best wishes on your tx puupy. Those new combos are gery promising indeed. I completed Sovaldi/Olysio tx for 12weeks Dec 21014.I have remained undetected, but suffer from varying side effects, which I never had vefore. I just pray they subside.  Thanks for.such great info, Vlessings Sunrise

 


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