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Author Topic: I am cured at 12 wks post harvoni and undetectable?  (Read 11204 times)

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Offline harvonitoo

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I am cured at 12 wks post harvoni and undetectable?
« on: August 10, 2015, 05:31:51 pm »
I took Harvoni for 24 wks (6 months) I was undetectable at 12 weeks already. Today my doc called me and told me congratulations, since you are at 12 weeks post treatment you are cured! I asked if I'm not supposed to be tested again at 6 months post treatment and he said Only if your liver functions have changed...

Soooooo I am considered cured for real ? What are my chances to relapse ( I had cirrhosis).... I'm trying to be cautious.

Offline Lynn K

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Re: I am cured at 12 wks post harvoni and undetectable?
« Reply #1 on: August 11, 2015, 08:18:04 pm »
http://blogs.hepmag.com/lucindakporter/2015/02/hepatitis_c_treatment_svr.html

Hepatitis C SVR12 vs SVR24: Trusting That We Are Truly Cured

My situation is similar to yours I am not totally ready to exhale yet but that is what many experts are saying is we are cured.

However with cirrhosis the plan for me going forwards is blood testing and abdominal ultra sound every 6 months to monitor for liver cancer and annual upper endoscopy to check to make sure my esophageal varicies have not returned. I will probably be seeing my doctors nurse for my annual appointments at the liver center.

Hep c is a virus if it is gone, it is gone. If it does not come back there isn't any virus to come back so the only way is to get infected again. There may be some rare late relapse in the future that remains to be seen but that would be the exception.

Best of luck to you and congrats
In health
Lynn
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline harvonitoo

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Re: I am cured at 12 wks post harvoni and undetectable?
« Reply #2 on: August 12, 2015, 11:17:47 am »
Thank you Lynn! Best of luck to you too and congrats as well!

Offline Mugwump

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  • My number of posts means nothing, piscor ergo sum!
Re: I am cured at 12 wks post harvoni and undetectable?
« Reply #3 on: August 22, 2015, 05:53:55 pm »
I started a 24 week post harvoni thread for this reason. I suspect the majority will be happy with having normal liver panel results confirming their cured status. But for those of us lucky enough to secure a VL test at 6 months post Harvoni it might just help lighten the doubts that will inevitably happen. Especially for those of us that are gt 1a and have experience tx failure(s) in the past! I believe Nicole managed to get a 24 week vl test confirmation so we can count her experience as at least one confirmation that Harvoni is indeed a complete cure for gt 1a! 8) 8)
Caution shameless self promotion below :-)
https://www.hepmag.com/article/eric-reesor-27742-782589663
DING DONG MY DRAGON (HCV) IS FINALLY DEAD!

Offline dragonslayer

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Re: I am cured at 12 wks post harvoni and undetectable?
« Reply #4 on: August 22, 2015, 08:30:14 pm »
Many of us GT1As have reached SVR24!   Trust it; its for real  :)
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline Mugwump

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  • Posts: 778
  • My number of posts means nothing, piscor ergo sum!
Re: I am cured at 12 wks post harvoni and undetectable?
« Reply #5 on: August 23, 2015, 02:23:22 am »
Many of us GT1As have reached SVR24!   Trust it; its for real  :)
Glad to hear that and I guess I should have read more. It is just up here in Canuck land, I am one the first of the first 24 weekers to reach 12 week svr on Harvoni and many 12 weekers that started tx just after I did have not reached 24 week svr quite yet but my nurse and GI will fill me in more on Sept 1 I am sure. I was approved only a few short days after Ottawa cleared the drug!

I believe I was the first on Vancouver Island to be treated with Harvoni other than a few who were in the clinical trials. At least this is what my clinic nurse tells me and the clinic is one of the best in the Province and is affiliated with the latest clinical research.

So a 24 week svr thread is not a bad idea IMO. I take it if no one responds that everyone has reached 24 week svr that also reached 12 weeks. So if it is a dead end thread I will not mind. I was just hoping to take some of the pressure off the 12 week check in thread. Not to split it up the idea!
Caution shameless self promotion below :-)
https://www.hepmag.com/article/eric-reesor-27742-782589663
DING DONG MY DRAGON (HCV) IS FINALLY DEAD!

Offline Lynn K

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Re: I am cured at 12 wks post harvoni and undetectable?
« Reply #6 on: August 23, 2015, 03:54:18 am »
I will be doing a 24 week in mid October will let y'all know when I know
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline davidsconfused

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  • Posts: 53
Re: I am cured at 12 wks post harvoni and undetectable?
« Reply #7 on: August 23, 2015, 05:48:15 am »
My Dr isn't doing a 6 months test. I don't go back until 6 months after the SVR12 which will be in Feb.

Offline Lynn K

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  • Posts: 4,546
  • Get tested, get treated, get cured, fight Hep c!
Re: I am cured at 12 wks post harvoni and undetectable?
« Reply #8 on: August 23, 2015, 11:37:22 am »
I will only be seeing my doctors nurse in April in Seattle. I go to the office once a year.

I get my labs done in the town I live in 25 miles away every 6 months and get my results on a web site/app MyChart. Also a 6 month abdominal ultrasound and an annual upper endoscopy.

I requested the 6 months post since I am having a blood draw then anyway.
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

 


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