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Author Topic: Cal on Vierkira Pak & Ribas  (Read 367485 times)

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Offline BillT

  • Member
  • Posts: 573
Re: Cal on Vierkira Pak & Ribas
« Reply #600 on: November 06, 2015, 02:27:02 pm »
Whats next Beto,walking on water? :o I very happy for you.That is just amazing.My doctor said they've been discussing doing Fibroscan at EOT12 to see what happens.You get the conga line lead tonight for that one. :)
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline beto

  • Member
  • Posts: 548
  • "no risk it, no biscuit"
Re: Cal on Vierkira Pak & Ribas
« Reply #601 on: November 06, 2015, 02:53:15 pm »
 :) thanks Bill...I was truly amazed...but, I still somehow wonder if there is a fluke.  I have been researching the scans reliability.  Nothing is perfect including the "gold standard" biopsy.  Some feel that is changing...still..

here is a study I found on FibroScan reliability.  over 2000 people in the study...

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071883/
HCV/nonA,nonB acute phase 1975
HCV detected active 1990
HCV persistent chronic diagnosis 1995
1995 liver enzymes mild elevations
1996 Biopsy F2 fibrosis
treatment naive geno 1-A
2000-to early 2015 Viral load 150, 000 to 800, 000
recent liver enzymes before treatment alt/ast 59to209,  Fibroscan F4,cirrhosis
start tx Harvoni 7/11/2015
6.5 week-UD-ast/alt 25/25
9wk-UD-ast18 alt23
10/3/15 completed tx
11/5/15 new fibroscan f0-f1 amazed
6wk EOT UD ast/alt 20/20
12EOT-UD-ast/alt19/21
25wk-SVR! 19/18

Offline BillT

  • Member
  • Posts: 573
Re: Cal on Vierkira Pak & Ribas
« Reply #602 on: November 06, 2015, 03:50:41 pm »
Here's a scary one for you.What if the problems with Viekira happened because it was prescribed to patients where it was contraindicated because the labs were wrong?
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #603 on: November 06, 2015, 03:57:47 pm »
Cal, that would be great!  Reversing cirosis is very difficult - but the liver is one of the few organs in the body that has regenerative potential.

Just finishing up my first full week on Viekira Pak and Ribavirin.  You were correct, as always, that the insomnia is the tougest side effect.  I have been very weak and tired these past couple of days.  I take my first blood test a week from Monday - hope I not suffering from anemia.

To be quite honest, I am somewhat pessimistic that this 24 week regimen will rid my body of the Hep C.  After 12 weeks of 0 viral load while on Harvoni and 4 weeks later a jump to 150,000+ viral count, I sure was a little depressed.  But, that depression has been replaced with pessimism
Good luck on the test results!  :)
Hi Mike,
Yes my fibroscan score wen roll back fibrosis as well from mt my tax. It does happen.

Mike it's understandable that you worry about relapse again, I do all the time. I try not to let myself get in my own way though. It's easy to get depressed about this. You have a long way to go yet and it's up to you if you do it mentally easy or make it hard on yourself. I know it's not that easy though!  But they didn't tx you long enough, that's all, you responded well.  It's all a crap shoot Mike, none of us know really, but we can be hopeful, not deluded, hopeful. I use Mindfulness to get me through. Google Ellen Langer, she has some you tube videos which introduce you to the practice, see if you like it. If you do, there's a book I'll recommend.
Till then Mike, don't sabotage yourself, remember these are powerful drugs especially with RIBA. I have a feeling you'll do fine. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #604 on: November 06, 2015, 04:02:07 pm »
Beto,
What f***ing brilliant news! You don't get much better than that! Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #605 on: November 06, 2015, 04:04:19 pm »
Here's a scary one for you.What if the problems with Viekira happened because it was prescribed to patients where it was contraindicated because the labs were wrong?
bill,
I said the same thing to Marianne the next day after the FDA warning. I'm sure there'll  be an enquiry. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #606 on: November 06, 2015, 04:06:45 pm »
Well, less than a week before I kiss ribas goodbye I just had my first stray awake alright insomnia attack!  Temazepam didn't work, I took 2. Feel like. CRap. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Bree

  • Member
  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #607 on: November 06, 2015, 04:18:40 pm »
Cal, I'll be so glad when you bid ado to the ribas.  I'm betting that will make a huge difference. 

I'm in the middle of the Happiness Trap book... I really like it. 
"I notice that I'm having the thought that ........"

I've done a version of this for awhile.  Noticing and accepting thoughts, but not giving them the power to be deemed as reality and also making a decision to choose a new or different thought.  Have you ever studied Katie Byron's work?

I'll look up the you tube video you mentioned.
Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline abacomike

  • Member
  • Posts: 25
Re: Cal on Vierkira Pak & Ribas
« Reply #608 on: November 06, 2015, 04:20:42 pm »
Beto,
What f***ing brilliant news! You don't get much better than that! Cal :)

I know you're right.  I think the side effects are getting to me.  I need to fight these side effects for a few months until I get used to them.  I called my doctor to see if he could suggest something better or stronger to allow me to get some sleep at night.  Unfortunately, he left for the day early so I will not actually speak with him until Monday.

I wonder what the % cure is for Viekira Pak + Ribavirin after failing with Harvoni and failing with Pegysis Interferon + Ribavirin.  Perhaps if the numbers are good, I will have reason for hope.

Thanks, Cal.
Contracted 1980 after blood transfusion
Diagnosed 1996
Ribavirin + Pegasis interferon failed 2006
Harvoni 12 week regimen - recurred week 16
Started Veikira Pak + Ribavirin 10/31/2015 for 24 weeks
Failed Harvoni and Veikira Pak - then had heart attack
Liver Cancer 4/12/2016; Liver resecton 9/22/2016
Started Epclusa 4/16/2017; Epclusa extended for 12 more weeks.  Viral undetected while on Epclusa
Viral Load 354,000 6/1/2015
Viral load 150,000 10/18/2015
Viral Load 550,000 4/16/2017
Genotype 1a

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #609 on: November 06, 2015, 04:37:54 pm »
Hi Bree,
Is this thought helpful, does it impact on my values I.e. To get through tx without adding angst? You've got it Bree! It so works. The thing will be to make it a habit and you're on your way if your reading that book anyway.

No I'm not familiar with Kaye Byron. Is she a Mindfulness gal? There was just a free Mindfulness Summit on through October where everyday you could log on and see a new world expert speaking. Google it, there may still be some links to speakers up.

Yes goodbye Ribas. Though they can take a while to leave the body, so it'll be a gradual thing, but it's got to be better!  Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #610 on: November 06, 2015, 04:51:00 pm »
Hi Mike,
Yeah, but I know it is easier said than done, I still have days when I can't handle it. But I know it's not helping me or achieving anything. It is what it is. If we relapse again (doubtful) then we retreat with new drugs coming through. Merck and Gilead.

Please stay away from Dr. Google. It can make you wiser but more anxious. The truth is with us there are no studies yet, it's too new. So they don't know. I wouldn't have txed this time with these drugs if I didn't think I could beat it. I'm a researcher in Genetic Epidemiology, believe me, the real publications are not on the net you have to be in research, Science, Medicine to access the publications.

General google can be dangerous, you can get information but not have all the facts to formulate an accurate  conclusion. You may think you have information but it needs other parts like a jigsaw.
You're on the path now, so walk it with calmness, not fear. Were on the path with you.

Yes get some drugs, sleep is so important. Says the girl who's been up all night! Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Bree

  • Member
  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #611 on: November 06, 2015, 04:59:36 pm »
Correction:  It's Byron Katie!  She has a process called "The Work"  You can google her.  She has a "Judge thy neighbor" worksheet.  The essense is 4 questions, which are:

1.  Is it true? (Yes or no. If no, move to 3.)
2.  Can you absolutely know that it's true? (Yes or no.)
3.  How do you react, what happens, when you believe that thought?
4.  Who would you be without the thought?

Then, there'a turn around.

Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline abacomike

  • Member
  • Posts: 25
Re: Cal on Vierkira Pak & Ribas
« Reply #612 on: November 06, 2015, 05:02:10 pm »
Your words and concepts are soothing and, of course, correct.  It's the old story of causes of stress - if I have no control over the variables affecting a situation, then there is no sense fretting or worrying about it.  It is what it is!  In this situation (fighting Hep C), 80%+ of the variables are uncontrollable.  The only controllable variables are the available treatments, i.e. Harvoni, Pegysis interferon, Ribavirin, Viekira Pak, etc.  if there is no data available on my predicament, then that too is an uncontrollable variable.

By the way, I looked up Ellen Langer, an amazing psychologist with revolutionary research.  Thanks.
Contracted 1980 after blood transfusion
Diagnosed 1996
Ribavirin + Pegasis interferon failed 2006
Harvoni 12 week regimen - recurred week 16
Started Veikira Pak + Ribavirin 10/31/2015 for 24 weeks
Failed Harvoni and Veikira Pak - then had heart attack
Liver Cancer 4/12/2016; Liver resecton 9/22/2016
Started Epclusa 4/16/2017; Epclusa extended for 12 more weeks.  Viral undetected while on Epclusa
Viral Load 354,000 6/1/2015
Viral load 150,000 10/18/2015
Viral Load 550,000 4/16/2017
Genotype 1a

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #613 on: November 06, 2015, 05:11:02 pm »
Hi Bree,
I just had a quick look at her stuff, I need to read more. Is she CBT or Mindfulness. She looks good. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline BillT

  • Member
  • Posts: 573
Re: Cal on Vierkira Pak & Ribas
« Reply #614 on: November 06, 2015, 05:20:00 pm »
Hi Mike,
           Some people have had problems with Harvoni,and damn near every had failed the Peg(only 30% success).The side effects suck but remember this isn't forever.I know it's hard to be positive when you feel bad but you need to hold on to the hope.Give it time and wait for your numbers to come back and see how it's working.You're a Viekirian now and we don't take no stuff from no stinking virus. 8)
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #615 on: November 06, 2015, 05:22:37 pm »
Hi Mike,

Yes! Is it certain, probable or only possible? If only possible as you say, uncontrollable but uncomfortable variable. Therefore out of our control and therefore no amount of worry or stress will be helpful. Glad you like Ellen Langer. She's particularly good.

Well be ok mike, if we keep our thoughts out of the spiral. Ribas do muck with the brain too, so only take a pinch of the crap it dishes up as true. It will work this time though, I a it relapsing again nit on my life script!  :)cal
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #616 on: November 06, 2015, 05:24:02 pm »
Hi Mike,
           Some people have had problems with Harvoni,and damn near every had failed the Peg(only 30% success).The side effects suck but remember this isn't forever.I know it's hard to be positive when you feel bad but you need to hold on to the hope.Give it time and wait for your numbers to come back and see how it's working.You're a Viekirian now and we don't take no stuff from no stinking virus. 8)

Right on Bill! Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Bree

  • Member
  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #617 on: November 06, 2015, 05:32:10 pm »
I think probably more mindfulness (or forget your mind;).  Not sure she has a label.  Her story is amazing.  She has huge numbers of followers.  I get her feed on my FB... it's a weekly thought.

She's more like "Who is the thinker of the thought".  Very much living in the present and very accepting of "what is".

Another book I loved (old book) is "The Secret of Letting Go". by Guy Finley  (want what life wants).  https://www.youtube.com/watch?v=TcYBWPCV37Q
(knowing that life will give you more than it asks you to give up)

I also really like Martha Beck and her writings (who had an endorsement on the cover of Happy Trap")  I get her on FB too.
Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline BillT

  • Member
  • Posts: 573
Re: Cal on Vierkira Pak & Ribas
« Reply #618 on: November 06, 2015, 05:48:59 pm »
That is a interesting article on the Fibroscan Beto.Are you going to get another done at some point?
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Bree

  • Member
  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #619 on: November 06, 2015, 05:53:43 pm »
Beto, I think you said you paid out of pocket for the scan?  How much is it?
Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline abacomike

  • Member
  • Posts: 25
Re: Cal on Vierkira Pak & Ribas
« Reply #620 on: November 06, 2015, 05:57:33 pm »
Hi Mike,

Yes! Is it certain, probable or only possible? If only possible as you say, uncontrollable but uncomfortable variable. Therefore out of our control and therefore no amount of worry or stress will be helpful. Glad you like Ellen Langer. She's particularly good.

Well be ok mike, if we keep our thoughts out of the spiral. Ribas do muck with the brain too, so only take a pinch of the crap it dishes up as true. It will work this time though, I a it relapsing again nit on my life script!  :)cal

It's just been a rough year for me.  My son was diagnosed with a malignant brain tumor last October.  He went through 6 months of proton radiation and we were thrilled to learn it killed the tumor.  Then, my Dad passed away on July 1st of this year.  I was his care giver and lived with him for 15 years to care for his dementia and eventual Alzheimer's.  At that same time I was put on Harvoni.  Things are just piling up on me, that's all.

Staying with this forum will get me through the next 6 months.
Contracted 1980 after blood transfusion
Diagnosed 1996
Ribavirin + Pegasis interferon failed 2006
Harvoni 12 week regimen - recurred week 16
Started Veikira Pak + Ribavirin 10/31/2015 for 24 weeks
Failed Harvoni and Veikira Pak - then had heart attack
Liver Cancer 4/12/2016; Liver resecton 9/22/2016
Started Epclusa 4/16/2017; Epclusa extended for 12 more weeks.  Viral undetected while on Epclusa
Viral Load 354,000 6/1/2015
Viral load 150,000 10/18/2015
Viral Load 550,000 4/16/2017
Genotype 1a

Offline Bree

  • Member
  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #621 on: November 06, 2015, 06:03:32 pm »
That's a lot to deal with Mike.  "Life is in session" even though we are on treatment.  You've had your share.  That was generous of selfless to be there for your Dad in that way.  I'm sure life will reward you for your kindness of spirit. I'm glad you son is better and now it is your turn!

I think this just might be your time!  Hang in there.  Warmly, Bree
Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline beto

  • Member
  • Posts: 548
  • "no risk it, no biscuit"
Re: Cal on Vierkira Pak & Ribas
« Reply #622 on: November 06, 2015, 06:14:38 pm »
mike...wow...you are another one of those tough survivors.  I am so sorry for your trials.  The hep, the cure, the failed cure or whatever is happening to oneself, is just that...then there is all the other battles we face.  Having to deal with an ailing son and a dying parent are too much for most people without a trying illness also going on.  You will get some breaks my friend.  In the meantime, you are a testimony of strength.

Bill- I expect that my doc is sceptical and will consider another to make sure.

Bree- I payed out of pocket for the one back in June, because of my insurence.  It was only 350.00, way less than a biopsy and takes 10 minutes.  This recent one was free because I was doing it for a fibrosis reversal study (I am not kidding, a good story) I was not accepted to the study.  I did not qualify because my numbers we to low.
HCV/nonA,nonB acute phase 1975
HCV detected active 1990
HCV persistent chronic diagnosis 1995
1995 liver enzymes mild elevations
1996 Biopsy F2 fibrosis
treatment naive geno 1-A
2000-to early 2015 Viral load 150, 000 to 800, 000
recent liver enzymes before treatment alt/ast 59to209,  Fibroscan F4,cirrhosis
start tx Harvoni 7/11/2015
6.5 week-UD-ast/alt 25/25
9wk-UD-ast18 alt23
10/3/15 completed tx
11/5/15 new fibroscan f0-f1 amazed
6wk EOT UD ast/alt 20/20
12EOT-UD-ast/alt19/21
25wk-SVR! 19/18

Offline Bree

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  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #623 on: November 06, 2015, 06:19:44 pm »
Great reason not to qualify Beto!
Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline beto

  • Member
  • Posts: 548
  • "no risk it, no biscuit"
Re: Cal on Vierkira Pak & Ribas
« Reply #624 on: November 06, 2015, 06:36:39 pm »
a good problem to have...no doubt
HCV/nonA,nonB acute phase 1975
HCV detected active 1990
HCV persistent chronic diagnosis 1995
1995 liver enzymes mild elevations
1996 Biopsy F2 fibrosis
treatment naive geno 1-A
2000-to early 2015 Viral load 150, 000 to 800, 000
recent liver enzymes before treatment alt/ast 59to209,  Fibroscan F4,cirrhosis
start tx Harvoni 7/11/2015
6.5 week-UD-ast/alt 25/25
9wk-UD-ast18 alt23
10/3/15 completed tx
11/5/15 new fibroscan f0-f1 amazed
6wk EOT UD ast/alt 20/20
12EOT-UD-ast/alt19/21
25wk-SVR! 19/18

Offline Cal

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  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #625 on: November 06, 2015, 07:31:48 pm »
It's just been a rough year for me.  My son was diagnosed with a malignant brain tumor last October.  He went through 6 months of proton radiation and we were thrilled to learn it killed the tumor.  Then, my Dad passed away on July 1st of this year.  I was his care giver and lived with him for 15 years to care for his dementia and eventual Alzheimer's.  At that same time I was put on Harvoni.  Things are just piling up on me, that's all.

Staying with this forum will get me through the next 6 months.
Oh boy Mike,
I am so sorry. You have had one major stress after another, your nervous system has taken a thrashing. Have you had any support during this trying time? I see a Mindfulness Psychologist. She helps me stay on course. Because life does get more stressful, there are more adversities as we get older. Looking after your Dad must have been very difficult at times, and your son, well that is so awful and I am so glad he us well again. It all comes at once sometimes, but if it's one thing after Another, on top of dealing with the pain and physical and mental stress of treating, relapsing and living with HCV , then it can move into a stress disorder. So I really want you to have some support if possible. It's your call of course. You know if extra support would help or not. Yes it's down to us to do this, but sometimes we just can't do it all alone.
We'll do everything we can to support you Mike, you're one of the Forum gang now. You're a Viekerian too! Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline BillT

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  • Posts: 573
Re: Cal on Vierkira Pak & Ribas
« Reply #626 on: November 06, 2015, 08:13:40 pm »
You've taken a huge beating Mike but remember that those around you have also.It sounds like you've been there for everyone else but you need to take care of yourself.Not just for yourself but for them as well.One step at a time Mike and if you need to unload you know where we are.This is one fight you're not in alone.GL
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Philadelphia

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  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: Cal on Vierkira Pak & Ribas
« Reply #627 on: November 10, 2015, 05:14:47 am »
That's a lot to deal with Mike, as others have said. Why di you need to fight the sx? Sometimes it's useful to just stay in the river and have it take you where it will. I was on 24 weeks of VP + Riba and every now and then just gave in tot he crap piling up, lay on the lounge for a day and pulled the blanket up around my ears.

Maybe you have a a lot of things to do, of course, and only you know what is best for you. But every now and then a day recharging my batteries was necessary. Good luck with evrything.

Cal, are you off riba yet? 
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Cal

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  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #628 on: November 10, 2015, 08:43:21 pm »
Philly,
I'm off Ribas in 2 days. 12 week mark. Wahoo! Horrible things, trashed me well and truly. I'm having a V/l on Friday and LFTS as my LFTS have been raising steadily over the past month. I'm worried but Doctor isn't. If I've relapsed I come off it straight away (when he gets back from the San Francisco Conference.)     If not I do another month on Viekira.  So tx is a but nebulous  for me at moment.  Not happy Jan.  :-[cal
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline abacomike

  • Member
  • Posts: 25
Re: Cal on Vierkira Pak & Ribas
« Reply #629 on: November 10, 2015, 08:58:21 pm »
That's a lot to deal with Mike, as others have said. Why di you need to fight the sx? Sometimes it's useful to just stay in the river and have it take you where it will. I was on 24 weeks of VP + Riba and every now and then just gave in tot he crap piling up, lay on the lounge for a day and pulled the blanket up around my ears.

Maybe you have a a lot of things to do, of course, and only you know what is best for you. But every now and then a day recharging my batteries was necessary. Good luck with evrything.

Cal, are you off riba yet?

Philadelphia, thanks for the feedback.  I am feeling a little better than I did last week.  I just let the disappointment get to me.  The side-effects "seem" less harsh - I've been able to do my 1-1/2 mile walk the past two days.  The only part I am a little frustrated with is the inability to fall asleep quickly and to stay asleep.  I go to bed around midnight, fall asleep about one-ish, but I awaken at 3:00 or 4:00 AM.  So the tiredness and weakness remains at the forefront.  I had none of these side-effects with Harvoni.  I get the sweats every night between 7:30 and 9:00 PM.  So I usually lower the A/C a degree or two.

I am just hoping that my body gets used to the medications and tracts less re: side-effects.  I just make it my priority to get up, go walking and take care of grocery shopping, banking, etc.  I must get exercise - that will eventually allow me to sleep better.

Taking my first 2-week blood tests a week from today.  So I'll know if this is working in two weeks when the results are back.  I'll also will find out if blood counts are in normal range and how my liver enzymes are.

Thanks everyone for your support.  Have a great evening (day for Cal) everyone.
Contracted 1980 after blood transfusion
Diagnosed 1996
Ribavirin + Pegasis interferon failed 2006
Harvoni 12 week regimen - recurred week 16
Started Veikira Pak + Ribavirin 10/31/2015 for 24 weeks
Failed Harvoni and Veikira Pak - then had heart attack
Liver Cancer 4/12/2016; Liver resecton 9/22/2016
Started Epclusa 4/16/2017; Epclusa extended for 12 more weeks.  Viral undetected while on Epclusa
Viral Load 354,000 6/1/2015
Viral load 150,000 10/18/2015
Viral Load 550,000 4/16/2017
Genotype 1a

Offline Scoutdoy

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  • Posts: 452
Re: Cal on Vierkira Pak & Ribas
« Reply #630 on: November 10, 2015, 11:06:35 pm »
Cal, if you were at 54 after 2 weeks,,,your gonna be undetected...have faith....we are all rooting for you...


Scout
F/49yrs
Genotype 1a
infected 1987-tatoo/military?
Diagnosed 2007
Biopsy F-0
vl 13,900,000
AST 23
ALT 19
Harvoni Treatment 7/27/2015
4 week lab --<12 negative...AST 23 ALT 15
6 week lab -- Undetected.....AST 17 ALT 10
8 week lab---undetected.......AST15 Alt 10
12 week lab---UNDETECTED....AST 15 ALT 9
12 week EOT--1/13/2016----UNDETECTED!
24 week EOT ----UNDETECTED  --AST 18 ALT 12
I AM FREE!

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #631 on: November 11, 2015, 02:15:22 am »
Scout,
Thanks so much. It means a lot to me. But I have to be realistic, I work on the better to be prepared for bad news than ignore the warnings. But you're right. It ain't over till the fat lady sings! I'm in with a chance. What a great forum and great woman you are. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Bree

  • Member
  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #632 on: November 11, 2015, 02:23:13 am »
Cal, I don't know what's happening.  I think you are o.k.  I think once you are done with the ribas and have a little time to recover from that it will really help.  I know you will be relieved to get these next blood tests so you can assess things... I still feel like thing will be o.k.  Please try not to worry... I know it's hard, but you deserve some peace.  Love, Bree 8)
Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline Else

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  • Posts: 523
  • Appeal, appeal, and appeal again!
Re: Cal on Vierkira Pak & Ribas
« Reply #633 on: November 11, 2015, 12:50:14 pm »
Hi Cal!  I've always thought there was an upside to pessimism.  I'm rarely truly disappointed and often happily surprised.   8)

I'm so glad you're done with the ribas!  But from what I've read here it will take a while for the side effects from them to subside.  Think of yourself as a boxer who just went the 15 round distance.  THAT is success!  Of course you're waiting for a good decision on the match, but in the meantime... ouch.  Lots and lots of R'nR for you!
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Cal on Vierkira Pak & Ribas
« Reply #634 on: November 11, 2015, 05:09:44 pm »
Today must be your last day of ribavirin, Cal. I know what a good feeling that is! Even though it takes a while to clear the system, I felt an inner strength (and calm) return to me once I was no longer ingesting the ribas daily. Congrats on that. And good luck with all else. I wouldn't worry too much about slightly elevated LFTs. There can be so many things that can cause that.

stay strong,
kim :)
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline BillT

  • Member
  • Posts: 573
Re: Cal on Vierkira Pak & Ribas
« Reply #635 on: November 11, 2015, 08:59:49 pm »
Hi Cal,
        Relax and wait for the lab results.We all know that's easier said than done but you've done great so far and I'm sure you'll be pleased when you get them.I'm glad that you're finishing the ribas.I didn't know if I was ever going to be able to put the knives back in the drawer.You're going to be fine Hun.You're a Viekirian and as our motto says "We don't take no stuff from no stinking virus.". 8)
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #636 on: November 11, 2015, 09:04:26 pm »
Cal, I don't know what's happening.  I think you are o.k.  I think once you are done with the ribas and have a little time to recover from that it will really help.  I know you will be relieved to get these next blood tests so you can assess things... I still feel like thing will be o.k.  Please try not to worry... I know it's hard, but you deserve some peace.  Love, Bree 8)

Hi Bree,
Thanks for your encouragement, if anyone would be positive for me, it would be you 8) I'm ok. I am taking my last ribas tonight (it's midday now) so yes it will be a big relief. They have really knocked the stuffing out of me. Yes I have the bloods tomorrow and results next Wednesday. I am trying not to worry. It is what it is. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline BillT

  • Member
  • Posts: 573
Re: Cal on Vierkira Pak & Ribas
« Reply #637 on: November 11, 2015, 09:09:20 pm »
BTW Cal,
            I get my labs done tomorrow to but i won't know until Friday what they are.Don't start the party without me. ;)
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #638 on: November 11, 2015, 09:24:44 pm »
Hi Cal!  I've always thought there was an upside to pessimism.  I'm rarely truly disappointed and often happily surprised.   8)

I'm so glad you're done with the ribas!  But from what I've read here it will take a while for the side effects from them to subside.  Think of yourself as a boxer who just went the 15 round distance.  THAT is success!  Of course you're waiting for a good decision on the match, but in the meantime... ouch.  Lots and lots of R'nR for you!

Hi Else, I like that upside to pessimism :P Thanks for giving me permission to be real. I have always been an optimist, but this is different! We are all facing this health crisis, but some will make it and some won't it's a fact. But I am working on managing the reality with mindfulness. It's now about how I cope until I know and if I relapse how I cope with that. If I make medical history, then I promise to be the optimist I used to be once again. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #639 on: November 11, 2015, 09:28:17 pm »
Today must be your last day of ribavirin, Cal. I know what a good feeling that is! Even though it takes a while to clear the system, I felt an inner strength (and calm) return to me once I was no longer ingesting the ribas daily. Congrats on that. And good luck with all else. I wouldn't worry too much about slightly elevated LFTs. There can be so many things that can cause that.

stay strong,
kim :)

Yes Kim tonight is the last ribas, Woohoo, It's Week 12 today, I would have been finishing EOT and all, but I am finishing the ribas so that's a cause to celebrate. One more month of Viekira. Thanks for telling me about the calm. I shall relish that! Yes I know LFTs can be elevated with other things, I am hoping that is the case of course. I am having a lot of liver pain again, letting that be.....Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #640 on: November 11, 2015, 09:30:58 pm »
Hi Cal,
        Relax and wait for the lab results.We all know that's easier said than done but you've done great so far and I'm sure you'll be pleased when you get them.I'm glad that you're finishing the ribas.I didn't know if I was ever going to be able to put the knives back in the drawer.You're going to be fine Hun.You're a Viekirian and as our motto says "We don't take no stuff from no stinking virus.". 8)

HI Bill,
I am a Viekerian and I will stand by our motto. Cal 8)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #641 on: November 12, 2015, 04:16:49 pm »
Going for my 12 week V/L now. Sooooo nervous. But I won't know till next Wednesday, this is torture! Cal :-\
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Cal on Vierkira Pak & Ribas
« Reply #642 on: November 12, 2015, 04:18:09 pm »
Going for my 12 week V/L now. Sooooo nervous. But I won't know till next Wednesday, this is torture! Cal :-\

I am sure you'll do great - Cal. You'll pass with flying colours!

kim :)
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Scoutdoy

  • Member
  • Posts: 452
Re: Cal on Vierkira Pak & Ribas
« Reply #643 on: November 12, 2015, 04:19:17 pm »
I know exactly where you are at. It'll be ok...take the test and find something to occupy yourself. You will be undetected...have faith


Scout
F/49yrs
Genotype 1a
infected 1987-tatoo/military?
Diagnosed 2007
Biopsy F-0
vl 13,900,000
AST 23
ALT 19
Harvoni Treatment 7/27/2015
4 week lab --<12 negative...AST 23 ALT 15
6 week lab -- Undetected.....AST 17 ALT 10
8 week lab---undetected.......AST15 Alt 10
12 week lab---UNDETECTED....AST 15 ALT 9
12 week EOT--1/13/2016----UNDETECTED!
24 week EOT ----UNDETECTED  --AST 18 ALT 12
I AM FREE!

Offline Bree

  • Member
  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #644 on: November 12, 2015, 05:05:57 pm »
Yes, Cal this is a good thing.   You'll be happy once you know so you can relax.  It will be a good result.  Apply the mindful techniques about helpful thoughts 8)
Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline BillT

  • Member
  • Posts: 573
Re: Cal on Vierkira Pak & Ribas
« Reply #645 on: November 12, 2015, 06:14:24 pm »
Hi Cal,
        I just got my labs done today and will find out tomorrow so I understand the nervousness.I'm looking at your numbers and was wondering if this is your first blood draw since week 2?You're VL dropped from 9M to 54 in 2 weeks so something good happened,and you've got 10 more weeks behind you since then,and 4 more weeks to go.Try to think about that and have some faith in the progress you've seen already. :)
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Else

  • Member
  • Posts: 523
  • Appeal, appeal, and appeal again!
Re: Cal on Vierkira Pak & Ribas
« Reply #646 on: November 12, 2015, 06:38:31 pm »
Waiting blows.  Do you ever listen to audiobooks?  I've found one can still worry and let the mind wander when watching something.  Not so much with an audiobook.
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #647 on: November 12, 2015, 08:29:39 pm »
Thanks everyone,
You're all so supportive and positive, what would I do without you? Yes I have been applying mindfulness and am not too bad mentally right now. We'll see what Wednesday brings.

Bill,
No I've had LFT's and my ALT and AST has been steadily rising over the past 4 weeks. We don't know why hence the V/L. In Australia they are happy to let you wallow with a 2 week VL and a 12 week post EOT VL.
If I'm UND then the rise is from something else? I am having lots of liver area pain? But I need to get through tx first. Hopefully I haven't relapsed which is what we're checking. I'm hopeful, but not delusional. As a previous relapser I know this trip ::) But like I said I'm not freaking out yet. I'll save that for Wednesday. SO be warned everyone! Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #648 on: November 12, 2015, 08:32:12 pm »
Hi Else,
My Dad listens to audio books, they are great. I can't concentrate very well. I can't read a book or anything. The ribas scatter your brain. I watch TV but it's so boring after 3 months of it! Though I have watched a few good Series. I am about to watch Amy Schumer I love that chick! Cal ;D
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Else

  • Member
  • Posts: 523
  • Appeal, appeal, and appeal again!
Re: Cal on Vierkira Pak & Ribas
« Reply #649 on: November 12, 2015, 09:39:34 pm »
Rest well and enjoy your weekend!
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline KimInTheForest

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  • Posts: 1,972
  • Believe in yourself
Re: Cal on Vierkira Pak & Ribas
« Reply #650 on: November 12, 2015, 10:05:41 pm »
Hi Else,
My Dad listens to audio books, they are great. I can't concentrate very well. I can't read a book or anything. The ribas scatter your brain. I watch TV but it's so boring after 3 months of it! Though I have watched a few good Series. I am about to watch Amy Schumer I love that chick! Cal ;D

I love Miss Fisher's Murder Mysteries, set in 1920s Melbourne and featuring a very self-possessed female detective played by Essie Davis. Do you watch that, Cal? I bet you would like it! :)

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #651 on: November 15, 2015, 05:45:12 pm »
Else,
Thanks I had a great weekend away. Feel so ill, bloody ribas are giving me skin splits and insomnia now. Is there no end to this drug? V/l results in 2 days! Freaky. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #652 on: November 15, 2015, 05:46:14 pm »
Oh Kim,
I do watch mrs Fischer! I didn't know it was on in the u.s. Too! It's great . Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline BillT

  • Member
  • Posts: 573
Re: Cal on Vierkira Pak & Ribas
« Reply #653 on: November 15, 2015, 06:13:32 pm »
Hi Cal,
         I was posting to Jaf just now saying that the three of us find out this week where we stand.At least you're done with the riba and you can get that out of your system and move on from it.That has to be a small blessing in itself.My doctor told me my white count was up.It's odd that I felt great when I saw her Friday(got the labs Thursday)and today I feel like I'm coming down with something.Maybe I was when I had the bloods done and that's what they picked up.Anyway we have a big week coming up and I have faith we're going to all get great news.Everyone please fasten your seatbelts and put your trays in the upright position.  8)
« Last Edit: November 15, 2015, 06:15:22 pm by BillT »
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline dearprudence

  • Member
  • Posts: 121
Re: Cal on Vierkira Pak & Ribas
« Reply #654 on: November 15, 2015, 06:29:49 pm »
Else,
Thanks I had a great weekend away. Feel so ill, bloody ribas are giving me skin splits and insomnia now. Is there no end to this drug? V/l results in 2 days! Freaky. Cal :)
Hang in there Cal - it will pas in time.

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #655 on: November 15, 2015, 07:22:11 pm »
Bill,
Yes the 3 of us. I'm on the 12 week bloods. I'll post as soon as I know. You do the same and we can celebrate together. Your ALT's are fantastic!

It's normal to get sxs at different times in tx. I would just go with it, float, clouds, bunnies, puppies, babies........Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #656 on: November 15, 2015, 07:23:08 pm »
Hi Prudence,
Yes, I'm moving with the goovin. Not long now. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #657 on: November 16, 2015, 04:49:35 pm »
Day 89.
Hi all,
I have awoken anxious today. Don't know if it's because tomorrow is D Day or it's the ribas. Guess I'll never know. Just keep on Dorying. Keep on swimming, keep on swimming! Seeing my Psychologist today. I haven't seen her for a while, I hope to get some techniques of mindfulness to stick in my tiny little mind, so I can cope with whatever us thrown at me tomorrow. Cal 8)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Else

  • Member
  • Posts: 523
  • Appeal, appeal, and appeal again!
Re: Cal on Vierkira Pak & Ribas
« Reply #658 on: November 16, 2015, 07:53:54 pm »
I can't wait to hear the news tomorrow, Cal.  I've been thinking of you.

Re: anxiety, have you ever tried diaphragmatic breathing?  Man, it really, really helps.

https://www.youtube.com/watch?v=0Ua9bOsZTYg

If that link doesn't work for you there are tons more on YouTube.  I use this technique a lot.  A whole lot!
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline KimInTheForest

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  • Posts: 1,972
  • Believe in yourself
Re: Cal on Vierkira Pak & Ribas
« Reply #659 on: November 16, 2015, 10:19:32 pm »
Good luck tomorrow, Cal! Eager to hear your news. Wishing all the best for you. :)

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Scoutdoy

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  • Posts: 452
Re: Cal on Vierkira Pak & Ribas
« Reply #660 on: November 16, 2015, 11:09:37 pm »
Cal, I am waiting for your words " undetected" what time is your appt? I was so excited before I got mine!!!! You got this....Really!


Scout
F/49yrs
Genotype 1a
infected 1987-tatoo/military?
Diagnosed 2007
Biopsy F-0
vl 13,900,000
AST 23
ALT 19
Harvoni Treatment 7/27/2015
4 week lab --<12 negative...AST 23 ALT 15
6 week lab -- Undetected.....AST 17 ALT 10
8 week lab---undetected.......AST15 Alt 10
12 week lab---UNDETECTED....AST 15 ALT 9
12 week EOT--1/13/2016----UNDETECTED!
24 week EOT ----UNDETECTED  --AST 18 ALT 12
I AM FREE!

Offline Bree

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  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #661 on: November 16, 2015, 11:31:10 pm »
I'm feeling good for you Cal.  I know it helps to hear... I just got a VL 6 weeks post treatment (for varying reasons) and it's UNDETECTED!!!  I didn't think it was bothering me that much but I noticed how good I slept that night!  I know you will too!
Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #662 on: November 17, 2015, 12:43:58 am »
I can't wait to hear the news tomorrow, Cal.  I've been thinking of you.

Re: anxiety, have you ever tried diaphragmatic breathing?  Man, it really, really helps.

https://www.youtube.com/watch?v=0Ua9bOsZTYg

If that link doesn't work for you there are tons more on YouTube.  I use this technique a lot.  A whole lot!

Hi Else,
Thanks for looking that up. I did yoga for years so yes have and do use that breathing a lot. It does work. Thanks for thinking about me. ;D Cal
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #663 on: November 17, 2015, 12:55:36 am »
Thanks Girls,
You're all so lovely and positive. My appointment is at 11am but I usually have to wait a bit. So I'll post as soon as I can I promise.

Bree that's great news. You have been a beacon of hope for me all along with your attitude.

Love to you all and sincerely thank you. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Philadelphia

  • Global Moderator
  • Member
  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: Cal on Vierkira Pak & Ribas
« Reply #664 on: November 17, 2015, 03:12:12 am »
All fingers crossed!
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Scoutdoy

  • Member
  • Posts: 452
Re: Cal on Vierkira Pak & Ribas
« Reply #665 on: November 17, 2015, 10:38:36 am »
Ok Bree...if it's 11 am in Australia what time is that in the states? I just don't have the brain power to figure it out today....did a 14 hour shift yesterday and getting ready to go back
F/49yrs
Genotype 1a
infected 1987-tatoo/military?
Diagnosed 2007
Biopsy F-0
vl 13,900,000
AST 23
ALT 19
Harvoni Treatment 7/27/2015
4 week lab --<12 negative...AST 23 ALT 15
6 week lab -- Undetected.....AST 17 ALT 10
8 week lab---undetected.......AST15 Alt 10
12 week lab---UNDETECTED....AST 15 ALT 9
12 week EOT--1/13/2016----UNDETECTED!
24 week EOT ----UNDETECTED  --AST 18 ALT 12
I AM FREE!

Offline beto

  • Member
  • Posts: 548
  • "no risk it, no biscuit"
Re: Cal on Vierkira Pak & Ribas
« Reply #666 on: November 17, 2015, 10:47:31 am »
Cal- your big day.  Everyone is pulling and praying.  This will be a slam dunk.  May all of the positive juju in the world be with with you today.
HCV/nonA,nonB acute phase 1975
HCV detected active 1990
HCV persistent chronic diagnosis 1995
1995 liver enzymes mild elevations
1996 Biopsy F2 fibrosis
treatment naive geno 1-A
2000-to early 2015 Viral load 150, 000 to 800, 000
recent liver enzymes before treatment alt/ast 59to209,  Fibroscan F4,cirrhosis
start tx Harvoni 7/11/2015
6.5 week-UD-ast/alt 25/25
9wk-UD-ast18 alt23
10/3/15 completed tx
11/5/15 new fibroscan f0-f1 amazed
6wk EOT UD ast/alt 20/20
12EOT-UD-ast/alt19/21
25wk-SVR! 19/18

Offline dearprudence

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  • Posts: 121
Re: Cal on Vierkira Pak & Ribas
« Reply #667 on: November 17, 2015, 11:14:03 am »
We're all with you today Cal - good luck!

Offline Philadelphia

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  • It only looks like I know what I'm doing
Re: Cal on Vierkira Pak & Ribas
« Reply #668 on: November 17, 2015, 04:04:27 pm »
Depends on where you are, Scoutdoy. Cal is non DLS, so an hour behind other eastern Aust states. For her right now it's 7am. In NYC it's 4pm, Chicago it's 3pm, Vancouver it's 1pm. Of course if you're in Newfoundland it's 5:30pm. Newfoundland is so awesome it has its own time zone.
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Bree

  • Member
  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #669 on: November 17, 2015, 04:07:31 pm »
Ok Bree...if it's 11 am in Australia what time is that in the states? I just don't have the brain power to figure it out today....did a 14 hour shift yesterday and getting ready to go back

Scout, I'm in Hawaii so don't know about Australia.  Think question was meant for Cal...
Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline Scoutdoy

  • Member
  • Posts: 452
Re: Cal on Vierkira Pak & Ribas
« Reply #670 on: November 17, 2015, 07:07:09 pm »
I am on Chicago time....thanks Philly....I am just really rooting for her and she has been with me on this forum since I started the treatment. Eeeeegadds the suspense of her tests are stressing me! Lol


Scout
F/49yrs
Genotype 1a
infected 1987-tatoo/military?
Diagnosed 2007
Biopsy F-0
vl 13,900,000
AST 23
ALT 19
Harvoni Treatment 7/27/2015
4 week lab --<12 negative...AST 23 ALT 15
6 week lab -- Undetected.....AST 17 ALT 10
8 week lab---undetected.......AST15 Alt 10
12 week lab---UNDETECTED....AST 15 ALT 9
12 week EOT--1/13/2016----UNDETECTED!
24 week EOT ----UNDETECTED  --AST 18 ALT 12
I AM FREE!

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #671 on: November 17, 2015, 10:13:43 pm »
Hi Friends,
The test was not back! I go back to my GP at 9am tomorrow morning. She  rang the lab and they are doing it now. I am exhausted, all that  anticipation. Now I have another sleepless night again. Oh well nevermind. My AST and ALP's have gone down slightly. 2 and 1 point respectively. My ALP is steadily getting higher though. Just  in normal range. It must be the Viekira or something other than the liver because it was always low before tx? I am still getting pain in the liver too. Tomorrow will reveal all.
Thanks for sending me your Juju! Your collective concern has really helped me to get through this, thank you. Cal  :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline BillT

  • Member
  • Posts: 573
Re: Cal on Vierkira Pak & Ribas
« Reply #672 on: November 17, 2015, 10:17:51 pm »
Go get some sleep Cal.I'm losing enough for both of us. ;)
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #673 on: November 17, 2015, 10:33:42 pm »
Thanks Bill,
I'll sleep and you can keep watch! Cal 8)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Scoutdoy

  • Member
  • Posts: 452
Re: Cal on Vierkira Pak & Ribas
« Reply #674 on: November 17, 2015, 11:06:07 pm »
Cal, tell your doctor that your forum friends are stressing over the delay in your results....LOL....waiting to hear your good results tomorrow!!!


Scout
F/49yrs
Genotype 1a
infected 1987-tatoo/military?
Diagnosed 2007
Biopsy F-0
vl 13,900,000
AST 23
ALT 19
Harvoni Treatment 7/27/2015
4 week lab --<12 negative...AST 23 ALT 15
6 week lab -- Undetected.....AST 17 ALT 10
8 week lab---undetected.......AST15 Alt 10
12 week lab---UNDETECTED....AST 15 ALT 9
12 week EOT--1/13/2016----UNDETECTED!
24 week EOT ----UNDETECTED  --AST 18 ALT 12
I AM FREE!

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #675 on: November 17, 2015, 11:14:41 pm »
Good on you Scout!

It was my exact thought as I left her office! I have friends on the other side of the world sweating on this! You're a doll. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #676 on: November 18, 2015, 03:26:37 am »
I just got a call from my GP. Vi/L UND!

I did not see that coming! I'm still in the race gang! Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #677 on: November 18, 2015, 03:30:05 am »
Thank you sincerely for sustaining me through this stressful time. You're amazing ;D
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Philadelphia

  • Global Moderator
  • Member
  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: Cal on Vierkira Pak & Ribas
« Reply #678 on: November 18, 2015, 03:40:39 am »
Whooo!!!!!!!!!
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Philadelphia

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  • It only looks like I know what I'm doing
Re: Cal on Vierkira Pak & Ribas
« Reply #679 on: November 18, 2015, 03:52:45 am »
(I'm very chuffed for you)
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Scoutdoy

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  • Posts: 452
Re: Cal on Vierkira Pak & Ribas
« Reply #680 on: November 18, 2015, 04:54:17 am »
I told you cal!! Now I can stop stressing waiting for your results! CONGRATULATIONS .....your on the cure train for sure.....


Scout
F/49yrs
Genotype 1a
infected 1987-tatoo/military?
Diagnosed 2007
Biopsy F-0
vl 13,900,000
AST 23
ALT 19
Harvoni Treatment 7/27/2015
4 week lab --<12 negative...AST 23 ALT 15
6 week lab -- Undetected.....AST 17 ALT 10
8 week lab---undetected.......AST15 Alt 10
12 week lab---UNDETECTED....AST 15 ALT 9
12 week EOT--1/13/2016----UNDETECTED!
24 week EOT ----UNDETECTED  --AST 18 ALT 12
I AM FREE!

Offline Cal

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  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #681 on: November 18, 2015, 05:17:21 am »
Thanks Phily and Scout,
I am feeling very lucky right now. Cal ;)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline gnatcatcher

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  • Posts: 1,372
Re: Cal on Vierkira Pak & Ribas
« Reply #682 on: November 18, 2015, 05:45:46 am »
Cal, wish you could see the huge grin on my face as I read your great news. -Gnatty
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline BillT

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Re: Cal on Vierkira Pak & Ribas
« Reply #683 on: November 18, 2015, 06:52:10 am »
I'm thrilled for you Cali.Of course we knew this was the only way it could turn out since you're a Viekirian,and as our motto says "We don't take no stuff from no stinking virus.". 8)
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Bree

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  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #684 on: November 18, 2015, 09:55:07 am »
I just knew it (from my crystal ball)!!!  I think it's all moving in a great direction for you Cal... trust that as best you can.  So happy for you!
Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline beto

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  • Posts: 548
  • "no risk it, no biscuit"
Re: Cal on Vierkira Pak & Ribas
« Reply #685 on: November 18, 2015, 10:21:13 am »
Well Cal,

You know that there is a huge collective relief with all your flock of concerned hep cronies.  If I could drink I'd be busting open a bottle of fine champagne.  This feels like Christmas.  Yipppeeeee!
HCV/nonA,nonB acute phase 1975
HCV detected active 1990
HCV persistent chronic diagnosis 1995
1995 liver enzymes mild elevations
1996 Biopsy F2 fibrosis
treatment naive geno 1-A
2000-to early 2015 Viral load 150, 000 to 800, 000
recent liver enzymes before treatment alt/ast 59to209,  Fibroscan F4,cirrhosis
start tx Harvoni 7/11/2015
6.5 week-UD-ast/alt 25/25
9wk-UD-ast18 alt23
10/3/15 completed tx
11/5/15 new fibroscan f0-f1 amazed
6wk EOT UD ast/alt 20/20
12EOT-UD-ast/alt19/21
25wk-SVR! 19/18

Offline KimInTheForest

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  • Believe in yourself
Re: Cal on Vierkira Pak & Ribas
« Reply #686 on: November 18, 2015, 11:41:50 am »
Fantastic news, Cal!! So happy for you.  :D

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Else

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  • Posts: 523
  • Appeal, appeal, and appeal again!
Re: Cal on Vierkira Pak & Ribas
« Reply #687 on: November 18, 2015, 01:42:46 pm »
Bwaaaaaa!  No words..... https://www.youtube.com/watch?v=cKg8IKfZ4cE  ;D ;D ;D
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline Cal

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  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #688 on: November 18, 2015, 05:05:57 pm »
Gnatty, Bill, Bree, Beto, Kim and Else,
Thank you all for putting up with all my paranoia and fears. You have been my anchors in this stormy sea of tx.
I'm a proud Viekarian Bill, now let's get that non alcoholic champagne and that virtual conga line and play! You guys are awesome. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline chuck3a

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  • I'm Neo, his guardian angel now
Re: Cal on Vierkira Pak & Ribas
« Reply #689 on: November 19, 2015, 04:07:50 am »
That's some great news Cal. so glad to hear/see the Undetected. Woo-hoo
diagnosed 2008 hep c 3a
viral load of 1656491 08/2015
treatment 2/2009 - 7/2009 pegasys and ribapak  failed
treatment starting: 09//16/2015 for 24 wks daklinza, sovaldi, and ribavirin
4/30/2013 alt - 133  ast - 143
7/24/2015 alt - 65    ast - 73   vl - 1656491
9/29/2015 alt - 21    ast - 24
10/14/2015 alt - 22   ast - 26   vl - not det.
11/11/2015 alt - 15   ast - 22
12-15-2015 alt - 14   ast - 21  vl - not det.
2-2-17 1 year 1 month hep c free
1-26-2016   alt - 11   ast - 19 vl - not det.

Offline Scoutdoy

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  • Posts: 452
Re: Cal on Vierkira Pak & Ribas
« Reply #690 on: November 19, 2015, 10:46:11 am »
Cal,,,,,,it's quite the stress relief isn't it? I know it was for me....just knowing that it is out of your system is wonderful. I remember sleeping really well the whole next week after I saw the words undetected


Scout
F/49yrs
Genotype 1a
infected 1987-tatoo/military?
Diagnosed 2007
Biopsy F-0
vl 13,900,000
AST 23
ALT 19
Harvoni Treatment 7/27/2015
4 week lab --<12 negative...AST 23 ALT 15
6 week lab -- Undetected.....AST 17 ALT 10
8 week lab---undetected.......AST15 Alt 10
12 week lab---UNDETECTED....AST 15 ALT 9
12 week EOT--1/13/2016----UNDETECTED!
24 week EOT ----UNDETECTED  --AST 18 ALT 12
I AM FREE!

Offline Madelief

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  • Posts: 60
  • Together we reach the bright site of te road
Re: Cal on Vierkira Pak & Ribas
« Reply #691 on: November 19, 2015, 03:06:39 pm »
Congratulations Cal , good news!!!
I am happy for you!!!!!!!!
Madelief
start Harvoni 11-02-2015 (november)
Bloodtest 11-09-2015 alt 45 (before treatment 145)
8 weeks treatment
F1
Bloodworks 11-23-2015
HCV not detectable!!!
Rest of the numers in a normal range : ))))

Offline Philadelphia

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  • It only looks like I know what I'm doing
Re: Cal on Vierkira Pak & Ribas
« Reply #692 on: November 19, 2015, 03:33:47 pm »
One more week and I should have my 12 post EOT LFTs, two weeks and I should have my VL. I hope it'll be more good news for this merry band of Viekirians :)
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Bree

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  • Posts: 576
  • "Today is a good day for a great day!"
Re: Cal on Vierkira Pak & Ribas
« Reply #693 on: November 19, 2015, 03:48:30 pm »
One more week and I should have my 12 post EOT LFTs, two weeks and I should have my VL. I hope it'll be more good news for this merry band of Viekirians :)

That's terrific Philly!
Dx 1997 Geno 1a
2002-2003 PEG Intron/riba (48 wks) respond/relapsed
Pre-Harvoni - Viral Load: 13.5 M - Log 7.1
Fibrosure Score F1-2  Pre-Treatment:  AST 73 / ALT 88

7/6/15 Started Harvoni (12 weeks)
10/5/15 HCV NOT DETECTED (One week post EOT)
11/9/15 NOT DETECTED!!! (6 wk post)
12/21/15 NOT DETECTED (12 wk post) 
3/14/16  NOT DETECTED (24 week post)AST 26 ALT 18
SVR ACHIEVED!!! 
CURED YES!!!

Offline Cal

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  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #694 on: November 19, 2015, 04:35:09 pm »
Thanks Chuck and Madalief,
It's a nice feeling fir sure! Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

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  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #695 on: November 19, 2015, 04:39:21 pm »
Hi Scout,
Yes it's a stress relief though my brain hasn't caught up, I was still having nightmares this morning. Hopefully, I can cram enough happiness in there to squeeze it out.  :) cal
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

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  • Posts: 957
  • Cal on Viekira Pak
Re: Cal on Vierkira Pak & Ribas
« Reply #696 on: November 19, 2015, 04:42:11 pm »
Phily,
OMG has it been 12 weeks already? You don't need good luck, you've had great LFTS and you're a sure thing fir SVR. What are you going to do with the rest if your life? Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Else

  • Member
  • Posts: 523
  • Appeal, appeal, and appeal again!
Re: Cal on Vierkira Pak & Ribas
« Reply #697 on: November 19, 2015, 08:13:25 pm »
Woo-hoo Philly!!!  Good news coming!  8)
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline dearprudence

  • Member
  • Posts: 121
Re: Cal on Vierkira Pak & Ribas
« Reply #698 on: November 20, 2015, 07:23:58 am »
WHOOHOO Cal! Great news! We Viekirans are getting stronger and stronger! Relax and enjoy!
Can"t wait to hear from you Philadelphia -  Cured, cured, and more cured coming down the pike.
Big smiles to all!
Prudence

Offline Philadelphia

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  • Member
  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: Cal on Vierkira Pak & Ribas
« Reply #699 on: November 20, 2015, 07:47:05 am »
If I am lucky enough to attain SVR12, I am going to work darned hard to make sure other people get the opportunity I have had. That's one thing I plan on doing. And travel. Lots of travel ;)
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

 


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