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Author Topic: ALT issue  (Read 5635 times)

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Offline KNW

  • Member
  • Posts: 5
ALT issue
« on: October 20, 2015, 03:14:17 pm »
Blood work sample taken on 8/04/2015
ALT 90
This has been pretty much my normal since I have been tacking it. Many years now.

Blood work sample taken on 8/24/2015 for FibroSure test
ALT 239

Sounds like false results, any thoughts ?

Just finished day 28 of Harvoni yesterday,




HCV since 1996  GT 1a
Began Harvoni – 12wk 08/22/15
08/15/15 VL 1,300,200
08/15/15 AST 59
08/15/15 ALT 90   
08/15/15 GGT 132
08/24/15 ALT 239
08/24/15 GGT 128
4 weeks VL undetected

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: ALT issue
« Reply #1 on: October 20, 2015, 06:31:37 pm »
Hi KNW,
IM not on Harvoni, but Viekira and high  ALT is a lab normality  that occurs

"All patients should have hepatic lab testing during the first four weeks of treatment. Approximately 1% of those taking Viekira Pak had post-baseline serum ALT levels greater than five times the upper limit of normal (ULN) after starting treatment. The incidence increased to 25% among women taking a concomitant ethinyl estradiol containing medication. "

Definitely  speak to your Doctor about it though. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: ALT issue
« Reply #2 on: October 20, 2015, 07:33:18 pm »
Blood work sample taken on 8/04/2015
ALT 90
This has been pretty much my normal since I have been tacking it. Many years now.

Blood work sample taken on 8/24/2015 for FibroSure test
ALT 239

Sounds like false results, any thoughts ?

Just finished day 28 of Harvoni yesterday,

Welcome, KNW. Before I was treated, I had a steady ALT for many years, but when it began to rise, did it ever! As you can see from my "signature file" below, my ALT was even higher than yours before I started Harvoni. It also jumped around quite a bit: my 4 readings during 2009 were 184, 100, 340, and 195.

Your ALT 239 might well be accurate. Since you just finished day 28, I assume you're about to take 4-week labs. Presuming Harvoni is working well for you (as it does for nearly everyone), your results should show a great drop in ALT -- into the normal range or very close to it.

Gnatty
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline KNW

  • Member
  • Posts: 5
Re: ALT issue
« Reply #3 on: October 21, 2015, 04:35:31 pm »
Thanks for the responses
HCV since 1996  GT 1a
Began Harvoni – 12wk 08/22/15
08/15/15 VL 1,300,200
08/15/15 AST 59
08/15/15 ALT 90   
08/15/15 GGT 132
08/24/15 ALT 239
08/24/15 GGT 128
4 weeks VL undetected

 


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