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Author Topic: Here we go,and I'm ready  (Read 95474 times)

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Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #200 on: November 28, 2015, 02:03:49 am »
Chuck,
We are the champions aren't we? Love Queen, love Freddie may he rip.  Nothing like a big singalong to Queen. I think we should include that with the conga line, some rowdy collective bohemian Rhapsody singing followed by we are the champions! Maybe even some air guitar to Hotel California? Cal 8)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline chuck3a

  • Member
  • Posts: 48
  • I'm Neo, his guardian angel now
Re: Here we go,and I'm ready
« Reply #201 on: November 28, 2015, 02:30:30 am »
Cal,
sounds like a plan to me. but we got to add some Floyd in there as we tear down the wall
diagnosed 2008 hep c 3a
viral load of 1656491 08/2015
treatment 2/2009 - 7/2009 pegasys and ribapak  failed
treatment starting: 09//16/2015 for 24 wks daklinza, sovaldi, and ribavirin
4/30/2013 alt - 133  ast - 143
7/24/2015 alt - 65    ast - 73   vl - 1656491
9/29/2015 alt - 21    ast - 24
10/14/2015 alt - 22   ast - 26   vl - not det.
11/11/2015 alt - 15   ast - 22
12-15-2015 alt - 14   ast - 21  vl - not det.
2-2-17 1 year 1 month hep c free
1-26-2016   alt - 11   ast - 19 vl - not det.

Offline BillT

  • Member
  • Posts: 573
Re: Here we go,and I'm ready
« Reply #202 on: November 28, 2015, 08:40:00 am »
Hi Tommy,I'm glad you're doing ok.My sx come and go.When I do get them it's just kind of a all around miserable feeling.The fatigue and insomnia are the worst parts of it now.The Godsend is that this is NOTHING like the Peg tx.

Ok now that we've talked shop it's on to the important stuff that life is made of.I'm not sure whether to laugh or cry at the thought of Cal sweating to the oldies. :) I miss the Twilight Zone and Outer Limits.They don't make them like that anymore.The Walking Dead is good but I still love the old one's.Else you should be ashamed asking someone here if they started the Walking Dead yet. ::) I do have to agree with everyone about American Horror Story.It started out good but once they went vampire they lost me.It does have a great cast though.

And now on to the music.When you don't know what to listen to put on some Beatles. ;) I love music.I was raised on the classics,and Big Band...and then Elvis came along and my father disowned me. 8)
« Last Edit: November 28, 2015, 08:43:12 am by BillT »
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Else

  • Member
  • Posts: 523
  • Appeal, appeal, and appeal again!
Re: Here we go,and I'm ready
« Reply #203 on: November 28, 2015, 11:45:11 am »
Well I might have to give American Horror another try then.

Chuck, those lyrics are perfect for this forum!  8) ;D 8)
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline BillT

  • Member
  • Posts: 573
Re: Here we go,and I'm ready
« Reply #204 on: November 28, 2015, 12:08:10 pm »
Give it another try Else,I just like zombies better. :) Btw In case anyone was wondering yes I was about 5 when my father disowned me because of Elvis.We used to go to Philly for Sunday dinners(I'm Italian and German  :))and whenever anyone was looking for me I was in the music room listening to my much older cousins records.My father was career military and he lightened up on Elvis when he joined the Army.
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline beto

  • Member
  • Posts: 548
  • "no risk it, no biscuit"
Re: Here we go,and I'm ready
« Reply #205 on: November 28, 2015, 12:23:53 pm »
hey Chuck,

Appropriate theme for us heppers...I should say x-heppers but, I don't want to jinx my EOT.  Prog Rock yo!  Dark side of the Moon, my fave Floyd.  King Crimson anybody? :D

Else- yea, whats the deal with the zombie apocalypse obsession.  I could not put the book 'World War Z' and still keep watching Walking Dead and Fear the Walking Dead, even though I an starting to get sick of all the characters.  Even Glen not dying barely affected me.  Twilight Zone was the bomb. 

Cal- Dancing party at Bree's house.
« Last Edit: November 28, 2015, 12:25:49 pm by beto »
HCV/nonA,nonB acute phase 1975
HCV detected active 1990
HCV persistent chronic diagnosis 1995
1995 liver enzymes mild elevations
1996 Biopsy F2 fibrosis
treatment naive geno 1-A
2000-to early 2015 Viral load 150, 000 to 800, 000
recent liver enzymes before treatment alt/ast 59to209,  Fibroscan F4,cirrhosis
start tx Harvoni 7/11/2015
6.5 week-UD-ast/alt 25/25
9wk-UD-ast18 alt23
10/3/15 completed tx
11/5/15 new fibroscan f0-f1 amazed
6wk EOT UD ast/alt 20/20
12EOT-UD-ast/alt19/21
25wk-SVR! 19/18

Offline BillT

  • Member
  • Posts: 573
Re: Here we go,and I'm ready
« Reply #206 on: November 28, 2015, 12:44:30 pm »
In The Court Of The Crimson King has always been one of my favorites Beto.Well done.
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #207 on: November 28, 2015, 05:04:10 pm »
Chuck,
All in all your just another brick in the wall! Yes Floyd. I was listening to it yesterday too. Have to have them at our virtual party at Brees.  Cal  8)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #208 on: November 28, 2015, 05:08:10 pm »
Hi Bill,
I'm glad you clarified the age thing. I was thinking how old is this dude?,he he. Yes Beatles fir sure, which songs?
My sister married in Vegas with an Elvis Impersonator. It was such fun. Vive Las Vegas.  I always lived Teddy Bear.  ;D cal
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #209 on: November 28, 2015, 05:12:25 pm »
Beto,
Had to you tube King Crimson. I may have heard if them and forgot,who knows. Not me? Cal  :o
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Rosie13

  • Member
  • Posts: 297
Re: Here we go,and I'm ready
« Reply #210 on: November 28, 2015, 05:47:21 pm »
Thinking of you guys & pow there you are talking scary shows!I have nightmares without the late night tv...so right now seeking music & comedy.easy watching but maybe after svr I'll get adventurous & do walking dead marathon!Tommy ,Else  & Cal glad to hear you are doing well.Chuck loved the we are champion lyrics...they sure fit!
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Here we go,and I'm ready
« Reply #211 on: November 28, 2015, 05:58:32 pm »
Hi Bill,
I'm glad you clarified the age thing. I was thinking how old is this dude?,he he. Yes Beatles fir sure, which songs?
My sister married in Vegas with an Elvis Impersonator. It was such fun. Vive Las Vegas.  I always lived Teddy Bear.  ;D cal

We have (or had, haven't seen him in a while) a "Frozen Elvis" in one of our city parks. Very authentically-dressed Elvis impersonator, a real lookalike, who would stand frozen in a typical Elvis pose until someone chucked a buck into his guitar case, at which point he comes to life and does a short bit of Jailhouse Rock or other favourites.

kim
« Last Edit: November 28, 2015, 11:14:30 pm by KimInTheForest »
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #212 on: November 28, 2015, 08:18:10 pm »
Hi Rosie,
I think comedy is the way to go whilst on tx :o I am loving your Amy Schumer. My favourite comedies are The Office (English) Extras (Ricky Gervais again), The I.T. Crowd written by my favourite comedy writer Graham Lineham, I also like your Big Bang Theory, Sheldon is hilarious, Alan Partridge (English), I love anything with Ben Stiller or Will Ferrel. Just love any comedy really! Cal ;D
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #213 on: November 28, 2015, 10:27:07 pm »
Hi Kim,
A frozen Elvis! What an imaginative and creative way to make money. I love the theatre of it all. I love Vegas so did my boys, we would holiday there anytime. Lots to do and see. The beautiful Grand Canyon wow! It was the best holiday. Cal ;D
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Here we go,and I'm ready
« Reply #214 on: November 28, 2015, 11:15:18 pm »
Hi Kim,
A frozen Elvis! What an imaginative and creative way to make money. I love the theatre of it all. I love Vegas so did my boys, we would holiday there anytime. Lots to do and see. The beautiful Grand Canyon wow! It was the best holiday. Cal ;D

I have always wanted to see the Grand Canyon. Still time. I hear it's not going anywhere... ;)

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline BillT

  • Member
  • Posts: 573
Re: Here we go,and I'm ready
« Reply #215 on: November 29, 2015, 08:53:04 am »
I'm talking about the Beatles Cal and you ask which song?Shame on you.You should know by now you can't pick just one. :)

https://www.youtube.com/watch?v=Y6GNEEi7x4c

Kim I saw a lot of the frozen artists in Europe but never a Elvis.lol I like the idea though.Barcelona had some amazing ones.I couldn't stay still for that long myself. :)

Rosie haven't you learned we do scary very well here? ::)
« Last Edit: November 29, 2015, 08:58:24 am by BillT »
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline beto

  • Member
  • Posts: 548
  • "no risk it, no biscuit"
Re: Here we go,and I'm ready
« Reply #216 on: November 29, 2015, 11:51:50 am »
Kim,

I live in the Grand Canyon state.  I have only been twice and that was just looking over the edge when there on business.  Tragic.  However, even from that perspective in is magnificent.  Photos just do not do it justice.
HCV/nonA,nonB acute phase 1975
HCV detected active 1990
HCV persistent chronic diagnosis 1995
1995 liver enzymes mild elevations
1996 Biopsy F2 fibrosis
treatment naive geno 1-A
2000-to early 2015 Viral load 150, 000 to 800, 000
recent liver enzymes before treatment alt/ast 59to209,  Fibroscan F4,cirrhosis
start tx Harvoni 7/11/2015
6.5 week-UD-ast/alt 25/25
9wk-UD-ast18 alt23
10/3/15 completed tx
11/5/15 new fibroscan f0-f1 amazed
6wk EOT UD ast/alt 20/20
12EOT-UD-ast/alt19/21
25wk-SVR! 19/18

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #217 on: November 29, 2015, 05:12:54 pm »
Kim,
Yes you must see the Grand Canyon! It defies words. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #218 on: November 29, 2015, 05:15:27 pm »
Bill,
I have records on my wall above the piano. I have Twist and Shout and Magical Mystery tour. You are right..which song? What a catalogue. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #219 on: November 29, 2015, 05:19:05 pm »
Beto,
We drive fron Vegas to the Grand Canyon. We hired a Cadillac, you have such big cars there! It was an amazing drive. Watching the landscape change from desert to lush forest. It snowed too, which made it even more beautiful. I agree it has to be seen to feel it. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline BillT

  • Member
  • Posts: 573
Re: Here we go,and I'm ready
« Reply #220 on: November 29, 2015, 05:30:42 pm »
I have a question for everyone.I'm sure it's happened but can anyone remember seeing a post that someone didn't get SVR or relapsed on Viekira?For the life of me can't remember seeing one here.Thanks
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #221 on: November 29, 2015, 07:53:56 pm »
Hi Bill,
I haven't seen a relapse on this forum, but I have on another forum. But you don't know the circumstances regarding whether they had previous tx with an NSA or an NS5A and had RAV. Resistance.
Statistically 30% of people will have resistance but it is so variable as to how it mutates. Also things like time lapsed between txs. Some resistant mutation go WILD after a few years. Though they really don't know what happens to them yet. There are no studies yet. Well there are small ones but nothing published or conclusive.
If your Geno 1b you'll be ok, that geno seems to not create RAVS but 1A is different. We are all guinea pigs here. It is all so new.
I have had resistance studies done, but haven't got them back, as they are being done by a Scientist as it's not a test commonly done. Though it will be with relapsers on these DAA's. I am a high risk relapse because I have txed on both those drugs, but that doesn't mean I won't SVR. Everyone is different. It is hard to be an exact Science. However, Merck and Gilead have new drugs on the table which override RAV's. So everyone will be txed sooner or later.  Cal
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline BillT

  • Member
  • Posts: 573
Re: Here we go,and I'm ready
« Reply #222 on: November 29, 2015, 08:47:09 pm »
That question was more out of curiosity Cal.I do know the meds are indicted for certain genotypes and other factors as you said.I got to thinking about it because I remember someone saying on the forum here(if I'm not mistaken)that in Australia they were 100% with the Viekria,and I didn't remember seeing anyone on this forum that had not gotten to SVR or relapsed.I just thought it was interesting,in a great way,that we haven't seen one yet here.Us Viekirians are an amazing species. 8)
 
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #223 on: November 30, 2015, 12:22:49 am »
Bill,
Viekirians do it better 8)

We are just getting into the SVR area now with our forum family. Viekira was passed by the FDA a lot later than Harvoni, so it's still in action. But we've had some bloody good results so far. Were in a new era of tx Bill. The stuff dreams are made of. Cal
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Cal

  • Member
  • Posts: 957
  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #224 on: November 30, 2015, 12:24:07 am »
Bill and conga liners,

Dancing to BTO. You ain't seen nothin yet! Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline sapphire101

  • Member
  • Posts: 238
  • "Stop worrying and start living"
Re: Here we go,and I'm ready
« Reply #225 on: November 30, 2015, 01:20:56 am »
Bill and Cal there was one forum member - cullotta -who posted that she did not make full treatment on vikiera pack. She experienced a return of viral load before end of treatment. Genotype 1b too which is really mysterious because that has been the dream genotype for easy treatment and good results.

Cullotta are if you are still out there please check back in with an update.
« Last Edit: November 30, 2015, 01:23:59 am by sapphire101 »
Sapphire101
Genotype 1a Fibrosis level 1
Viekira Pak with ribavirin 12 weeks
Pre treatment  VL  1.7 million, AST 45 ALT 65
EOT VL not detected, AST 21 ALT 21
12 week SVR not detected,24 week SVR not detected.
Cured! Class of 2015

Offline Philadelphia

  • Global Moderator
  • Member
  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: Here we go,and I'm ready
« Reply #226 on: November 30, 2015, 06:01:04 am »
My treating hospital is batting 100% so far on Viekira. No relapses, no breakthroughs. I'm looking good for their stats (see most recent figures below). I know of one person here who didn't clear but that's it.
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Cal

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  • Cal on Viekira Pak
Re: Here we go,and I'm ready
« Reply #227 on: November 30, 2015, 05:29:13 pm »
Hi Sappphire,
If Culotta had breakthrough before EOT then she would have had RAVs. 30% of the population naturally have RAVs let alone those of us who txed before on those resistance forming categories of drugs. Unusual that she was 1B that affords a very high clearance rate. But as I said statistically some of us won't clear. In waiting around to see if I relapse, I just wish I had had viral breakthrough during tx. I am not looking forward to my EOT 12 week wait in 13 days time!

Statistically some of us won't make it. But like I said, there are new resistance drugs from Merck and Gilead, which came out of the San Francisco Liver Conference 2 weeks ago. So it's brave new frontier for all of us.

Philly that's great that it's 100% at St. Vincents so far.  You'll be fine too. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline BillT

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Re: Here we go,and I'm ready
« Reply #228 on: December 03, 2015, 09:46:49 am »
Question,
             I was on the old treatment and took the riba.As I've said before I don't remember having the riba rage,and was wondering if the riba being prescribed now is the same as I took then?If it's not I'm thinking the rage could be part of whatever changes were made to it since then.Any thoughts?
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

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Re: Here we go,and I'm ready
« Reply #229 on: December 03, 2015, 05:52:57 pm »
Hi Bill,
I had RIBA rage with my previous tx! I seem to be especially sensitive to ribas. They have floored me this time. My skin slit open again yesterday and it's 3 weeks post ribas already. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline BillT

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Re: Here we go,and I'm ready
« Reply #230 on: December 06, 2015, 04:02:13 pm »
I've had 3 days of being nervous,stressed,anxious,and sleep is nonexistent.I have no idea what's going on.I'm still grateful I've had so few sx but this has been ugly and annoying.
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

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Re: Here we go,and I'm ready
« Reply #231 on: December 06, 2015, 04:50:33 pm »
Hi Bill,
Sorry you've got some horrible sxs there. I had anxiety in the beginning and got Valium from the GP. I also take a an ant histamine fir the itch which doubles as a sleep pill. But early days I took Temazepam. If it keeps going get some drugs, you need to sleep and being anxious and stressed is revolting. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Else

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Re: Here we go,and I'm ready
« Reply #232 on: December 06, 2015, 05:11:29 pm »
Hey Bill.  Insomnia exacerbates everything!  I'd listen to the Viekirians on this - maybe get some medication that helps with the anxiety short-term.

From what I've read on these forums, the ribavirin dispensed these days often does cause the exact side-effects you're describing.  And there's help for it!
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline Philadelphia

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Re: Here we go,and I'm ready
« Reply #233 on: December 07, 2015, 06:39:55 am »
Bill, the absolute WORST time for me was when I didn't get enough sleep. It magnified everything. It's the only time I truly lost it.

Do what you need to to get some sleep. You'll feel better almost immediately.
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline mjberwick

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Re: Here we go,and I'm ready
« Reply #234 on: December 08, 2015, 02:43:48 am »
Hi all this is Mike again, I contacted Hep C in 1983 and was diagnosed at the VA. Hospital with pneumonia , Hep non A non B and also I had Celulitis infection on my left shine, I was a pretty sick boy, will anyway I have Hep C 1a and frirosis score F3, I started the Harvoni Nd Ribavarin o Sept. 2nd, 2015, at the start of the 10th week I started having these horrible anxiety like I could not stand to be in my own skin, plus I started having really bad pain in my left rib cage, so the start of the 11th week I skipped a Saturday and Sunday dose of Ribavarin , on Monday I contacted my GI doctor and he convinced me not to stop the Ribavarin , so I took it on that Monday and I saw the Doc on Tuesday , I showed him how tore up my feet were all broke out and I explained the anxiety he prescribed me Xanax for it and it has helped some and I finished the rest of the Harvoni and Ribavarin on 11/24/2015, I'm still having the anxiety, but not as bad as before and my rib cage as stopped hurting and my feet seem to be getting better, but it's the anxiety that is still bothering me, I see the Doc on 12/15/2015 and I will find out if my blood work shows me free of the Hep C, I sure hope I didn't mess it up by missing two days of the Ribavarin , I was just wondering if anybody out there has an opinion about me missing two days of the Ribavarin , I still took the Harvoni I never missed a dose of the Harvoni, I would appreciate  any thoughts on this, my blood work at 4 weeks showed me clear of the Hep C, now I 'm really worrying, I hope I didn't go through 12 weeks and screw it up because of two days that I went crazy in my mind, I actually felt and thought that the Ribavarin was killing me.

Thanks Mike from California

Offline KimInTheForest

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Re: Here we go,and I'm ready
« Reply #235 on: December 08, 2015, 03:21:34 am »
Hi Mike. In my opinion, skipping those 2 days of ribavirin in your 11th week of a 12-week treatment is not likely to have any effect on your treatment outcome. Many people are dose-reduced on ribavirin by their doctors because of side effects, and in extreme cases ribavirin is sometimes stopped mid-way through treatment. From what I have heard, even those people are still getting cured with the new drugs. So I really don't think you need to worry about skipping 2 days of ribavirin at the tail end of your treatment.

As for the anxiety, it does take a while for the ribavirin side effects to wear off after finishing treatment. They don't go away immediately - perhaps because the ribavirin lingers in the system for so long.

Keep the faith. I'm sure you will have good news whenever you get your viral load done.

kim :)
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Philadelphia

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Re: Here we go,and I'm ready
« Reply #236 on: December 08, 2015, 03:21:53 am »
Hi Mike, while I didn't miss a dose of ribavirin, I did dose reduce from week 2 onwards due to skyrocketing bilirubin. From week 2 I only took 1 tablet am and 1 tablet pm instead of 3 tabs am and 2 tabs pm. 

I cleared the virus and I'm f4 and was a bit tricky to treat. thats my experience!
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline mjberwick

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Re: Here we go,and I'm ready
« Reply #237 on: December 08, 2015, 03:45:02 am »
Thanks guys, that information makes me feel a bit better, I still am having trouble sleeping at night, I'm usually up almost all night and finally might fall asleep around 5am and wake up around 10am, I wish I could fall asleep early so I could feel more refreshed and have more energy

Thanks Mike in California

Offline mjberwick

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Re: Here we go,and I'm ready
« Reply #238 on: December 08, 2015, 03:10:58 pm »
Hi guys, it's Mike from California again, you know I stopped taking all my vitamines when I started taking the Harvoni and Ribavarin because my doctor told me to stop all vitamines, I completed my 12 weeks on November 24th 2015, I hope it is ok to take them again because I started taking them again yesterday 12/7/2015, does anybody have any thoughts on this, I would appreciate any feed back.

Thanks Mike in California

Offline KimInTheForest

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Re: Here we go,and I'm ready
« Reply #239 on: December 08, 2015, 03:16:48 pm »
I think you are fine to resume vitamins and supplements after finishing treatment - unless you notice them causing you any problems (digestive upset, flank soreness, etc.). Just my opinion. I am not a doctor.

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Cal

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Re: Here we go,and I'm ready
« Reply #240 on: December 08, 2015, 05:06:45 pm »
Hi Mike,
RIBA is a mean drug and it can take months to get out of the system.  I stopped it after 12 weeks and am doing 17 weeks of Viekira. 
I have heard others on this forum talking about a phone number you can call at Gilead to speak to a nurse who can advise you about things like vitamins etc. anything medical to do with Harvoni. Try them.

Anxiety will pass.  I am on Valium for anxiety and I take Temazepam if I can't sleep.  You may need to get something to help with sleep. It sounds like your suffering unnecessarily. If you don't sleep then everything is worse, including anxiety. You need to sleep. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline BillT

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Re: Here we go,and I'm ready
« Reply #241 on: December 11, 2015, 07:08:11 am »
Today I complete week 8 and and pick up my last 4 weeks of meds.Don't get in my way at the pharmacy. 8)

There's so many of us finishing and I'm thrilled for all of us.It's getting better all the time. :)
« Last Edit: December 11, 2015, 07:11:16 am by BillT »
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline BillT

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Re: Here we go,and I'm ready
« Reply #242 on: December 11, 2015, 03:46:14 pm »
Well they won't do a VL again until EOT.My white count went from 11 to 13 but AST is 12 and my ALT 13.I. hate texting.Hell l hate phones? 8?
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline BillT

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Re: Here we go,and I'm ready
« Reply #243 on: December 14, 2015, 07:50:11 am »
I'm back at the beach so I can add more to the discussion I had at my appointment Friday.We talked about my white blood count being up.There was a discussion we had on a thread here about it taking longer to get the dragon out of the deep tissue.She said it takes out what's in the blood and we can show up UD but still have some in the liver and such that takes time to get.Also,and I forget who it was,said that they had a F4 scan when they started and dropped to a F1-F2.She told me they've had one person there that started at F-4 and dropped 10 points by EOT.I asked and they scheduled me for another Fibroscan 6 months EOT.Just wanted to pass all this on. 
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Cal

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Re: Here we go,and I'm ready
« Reply #244 on: December 15, 2015, 10:56:52 pm »
Hi Bill,
Yeah the virus hides, it's sneaky. I'm glad I did extra time to get the sneaky bits.
That's great news about the fibro score. Cal :)
HCV 30 years. Geno 1A.
Veikira Pak with ribas on Compassionate Access.
Brisbane. Australia. began 21.8.15.
17 weeks.  Previous non responder 2011.
V/L 9 million
2 week V/L 54
12 weeks V/L UND
No 17 week  EOT V/L
EOT Post 4 weeks UND.

Offline Else

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Re: Here we go,and I'm ready
« Reply #245 on: December 16, 2015, 10:23:20 am »
I'm so happy for you, Bill!  Here's to catching the sneaky bits!  8)
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline BillT

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Re: Here we go,and I'm ready
« Reply #246 on: December 24, 2015, 07:05:05 pm »
I can't believe that after tomorrow I only have 14 days left.I thought I was going to finish on the 9th but it turns out the 8th is my last day.I'm so over sucking down pills and I'm ready to be done with this.Happy Christmas to those that celebrate it,and Happy Holidays to those that don't. :)
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Philadelphia

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Re: Here we go,and I'm ready
« Reply #247 on: December 24, 2015, 07:16:58 pm »
Nearly there Bill!
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline BillT

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Re: Here we go,and I'm ready
« Reply #248 on: December 24, 2015, 07:49:12 pm »
I know Hun.I'm just feeling like I'm being pulled in every direction right now and I need some normal in my life again.Thanks
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Else

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Re: Here we go,and I'm ready
« Reply #249 on: December 24, 2015, 09:13:49 pm »
So close!!!  Hang in there.
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline chuck3a

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Re: Here we go,and I'm ready
« Reply #250 on: December 24, 2015, 11:45:47 pm »
Hi Mike,
on your insomnia problem, I had the same thing going on, going to sleep at 3-5am and waking up 6-8am, so I changed the time I took my doses, from 9am and 9pm to 6am and 5-6pm so I am able to go to sleep around midnight - 1am. but still waking up 3-4 am. unless I take something to help me sleep. then 5-6am. I normally only sleep 4-5 hrs a day, been like that my entire life, but now only sleeping 3-4 hrs a day. but there have been a few days where I only get 2 hrs of sleep. so you can try changing the time you take pills, for me 2 hours after I take my pills is when they kick in and I can feel them for about another 3-4 hours after that. the insomnia, extra energy, etc. 
diagnosed 2008 hep c 3a
viral load of 1656491 08/2015
treatment 2/2009 - 7/2009 pegasys and ribapak  failed
treatment starting: 09//16/2015 for 24 wks daklinza, sovaldi, and ribavirin
4/30/2013 alt - 133  ast - 143
7/24/2015 alt - 65    ast - 73   vl - 1656491
9/29/2015 alt - 21    ast - 24
10/14/2015 alt - 22   ast - 26   vl - not det.
11/11/2015 alt - 15   ast - 22
12-15-2015 alt - 14   ast - 21  vl - not det.
2-2-17 1 year 1 month hep c free
1-26-2016   alt - 11   ast - 19 vl - not det.

Offline Philadelphia

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Re: Here we go,and I'm ready
« Reply #251 on: December 25, 2015, 07:46:49 am »
Sometimes I think the closer we get to EOT the harder it becomes. It will end. This will be worth it.
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline BillT

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  • Posts: 573
Re: Here we go,and I'm ready
« Reply #252 on: December 25, 2015, 07:58:21 am »
I agree Philly.The odd thing is I take blood pressure meds every day and that doesn't bother me.It's just these meds and this treatment.

https://www.youtube.com/watch?v=zge6UEwUGn0
« Last Edit: December 25, 2015, 08:00:41 am by BillT »
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Philadelphia

  • Global Moderator
  • Member
  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: Here we go,and I'm ready
« Reply #253 on: December 25, 2015, 06:11:30 pm »
This is so much more important. So much more. I think that's why it's high pressure - it's high stakes.
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline BillT

  • Member
  • Posts: 573
Re: Here we go,and I'm ready
« Reply #254 on: December 26, 2015, 06:36:14 am »
Thanks Philly.I just mentally hit a rough patch for a few days.Today starts my last 14 days and I'm ready to go the distance and finish the dragon off. 8) 
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline beto

  • Member
  • Posts: 548
  • "no risk it, no biscuit"
Re: Here we go,and I'm ready
« Reply #255 on: December 26, 2015, 11:38:10 am »
Look at it this way Bill...you are undetected and your liver enzymes are hockey scores.  You have a s%#@ load of new friends that get you and you are no longer a biohazard  :)

That said, this is the place to spill the beans and not feel you have to edit your commentary.  You and many of the riba folks were hit pretty hard with sides.  The sleep thing has got to suck.  You will begin 2016 riba and hep free.  Good luck on the countdown.
HCV/nonA,nonB acute phase 1975
HCV detected active 1990
HCV persistent chronic diagnosis 1995
1995 liver enzymes mild elevations
1996 Biopsy F2 fibrosis
treatment naive geno 1-A
2000-to early 2015 Viral load 150, 000 to 800, 000
recent liver enzymes before treatment alt/ast 59to209,  Fibroscan F4,cirrhosis
start tx Harvoni 7/11/2015
6.5 week-UD-ast/alt 25/25
9wk-UD-ast18 alt23
10/3/15 completed tx
11/5/15 new fibroscan f0-f1 amazed
6wk EOT UD ast/alt 20/20
12EOT-UD-ast/alt19/21
25wk-SVR! 19/18

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: Here we go,and I'm ready
« Reply #256 on: December 26, 2015, 11:49:35 am »
Bill, ditto every word beto said. About those hockey scores: I have enzyme envy!
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline Else

  • Member
  • Posts: 523
  • Appeal, appeal, and appeal again!
Re: Here we go,and I'm ready
« Reply #257 on: December 26, 2015, 12:22:19 pm »
Enzyme envy?  ;D ;D  Good one.  No kidding, Bill.  Those are some fine looking numbers.  :D

So close to the finish line!  Maybe you'll get my post-treatment narcolepsy to make up for the insomnia.  Seriously.  I can't seem to stay awake past 7pm.  And it seems like Dec 21st was yesterday.

F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: Here we go,and I'm ready
« Reply #258 on: December 26, 2015, 01:04:07 pm »
Yup, Else, at about the same time period post-Tx the Sandman was visiting me a LOT. They say you can't make up lost sleep, but it sure felt like that was what was going on. You should be back to normal hours pretty soon.
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline Carly

  • Member
  • Posts: 15
Harvoni symptoms
« Reply #259 on: December 26, 2015, 04:52:17 pm »
Hello I have no idea where to post this so here goes. I have no support from family or friends and my side effects are getting worse at day 33. The first month I only had 3  bad days now I ache everywhere, can't think straight, my hands are killing me and so is my right hip. I had zero symptoms before I started and of course its worth it but I thought it would get easier but for me it's getting worse especially the fatigue.. My Dr has no input except asking me if I want to stop which of course I will not. All I want is some support that others go through this too. I was told zero to no side effects and its just not true. I am supposed to vacation tomorrow and frankly I am worried about going but the ticket is non-refundable and was booked before I was approved for the Harvoni. Any input on how to alleviate some of these side effects would be very much appreciated.
Thank you.

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: Here we go,and I'm ready
« Reply #260 on: December 26, 2015, 05:53:11 pm »
Carly, I'm sorry you are one of those who have a rough time on Harvoni. There are others here -- Slats1056 (real name Tommy) immediately comes to mind, due to your mentioning "can't think straight" and "fatigue." He's also been plagued by headaches and body aches. Despite all of his side effects, he managed to work full-time, be a family man, etc.

If you are not already drinking plenty of fluids, aim for one ounce per 2 pounds of body weight, minimum 8 cups/day of mostly water. And if you can continue to exercise daily despite the pain, you'll be better off than if you avoid all pain. I had intermittent, strong aches and pains, despite which I did as much of my regular exercise routine as I could, and I made sure to walk a lot.

Good for you that you plan to persevere. Your travel may actually be a good idea, since distraction is a scientifically documented form of pain relief!

These forums exist because many members have no support from family or friends. Here, we understand and will be your cheerleaders as you keep your eyes on the prize: an HCV-free life. You've already finished more than one bottle, so you're well on your way.

Gnatty
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline Carly

  • Member
  • Posts: 15
Re: Here we go,and I'm ready
« Reply #261 on: December 26, 2015, 06:05:17 pm »
Dear Gnatty!

Thank you so much for answering me! I am working full time albeit not up to expectations. I have had no headaches or insomnia but the fuzziness just started today. I am definitely not drinking enough water and I will start, thanks for the advice !

 Do you know if switching the time I take it would stop the daytime effects. My Dr had no advice, said it doesn't matter. I take it at 2:05 pm ( The exact time it was delivered to me thankfully) and by 6:00 pm I am usually feeling better. Its when I wake up @ 7:00 am until 6:00 pm that are the difficult hours. For some odd reason I cannot figure out the math to determine an alternative time to take it. Any thoughts?  2:00 am?

Thanks again for answering me.

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: Here we go,and I'm ready
« Reply #262 on: December 26, 2015, 07:47:33 pm »
Carly, you can definitely adjust the time so the side effects interfere as little as possible with what you need to do. A lot of people have adjusted their pill-taking time. It's best to adjust by two hours or so per day until you reach the time you prefer. As to what time is best, it'd be ideal if you can sleep through the worst, so you'll be conducting a scientific experiment to learn the best time. If you begin the gradual adjustment by taking the pill at noon (or 12:05) tomorrow, you can see if 5 am until 4 pm become the difficult hours. (Hopefully, you'll still be asleep through the first difficult hours.) If you then take the pill at 10 am on Monday, you'll see if the difficulties lessen at 2 pm, etc.

Harvoni definitely likes lots of fluids to help flush out the HCV evildoers. I wonder if insufficient water over time has led to the fuzziness. Please let us know what you discover.

Gnatty
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline BillT

  • Member
  • Posts: 573
Re: Here we go,and I'm ready
« Reply #263 on: December 26, 2015, 09:33:11 pm »
Hi Carly,
           You definitely came to the right place to get the support you need and questions answered.I feel bad now when I realize how minor my problems are when some people are getting hammered.The brain fog seems to hit a lot of people taking the Harvoni but tends to go away after a while.I'm on Viekira so I can't help much.I hope things get better for you.Keep us posted on how you're doing.
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline BillT

  • Member
  • Posts: 573
Re: Here we go,and I'm ready
« Reply #264 on: December 26, 2015, 09:51:07 pm »
Thank you Beto,Gnatty,and Else.I know I'm close and everything is looking good.Like I said I just had a few bad days.I'm going to suck it up,and shut up now like a true Viekirian and get this done.You all know just the right things to say. 8)
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline BillT

  • Member
  • Posts: 573
Re: Here we go,and I'm ready
« Reply #265 on: December 26, 2015, 10:56:09 pm »
I was just thinking(God help you all)that we should start a thread and list the of side effects and note what med,or meds seem to be causing them,and things that help(if any),and we could modify it as we go along.Just a thought.
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline BillT

  • Member
  • Posts: 573
Re: Here we go,and I'm ready
« Reply #266 on: December 28, 2015, 12:46:45 pm »
I was looking to see what I could find on the next generation of Hep C drugs.There wasn't much but I did find this.Have a look at page 3.

http://www.webmd.com/hepatitis/features/treatment-for-hep-c?page=3

I also found this that I posted in the HIV/HVC section.I thought the relapse because of a different strain that didn't show up in the initial tests was food for thought.

http://www.webmd.com/hepatitis/features/treatment-for-hep-c?page=3
« Last Edit: December 28, 2015, 12:53:32 pm by BillT »
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

 


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