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Author Topic: harvoni relapse  (Read 7511 times)

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Offline melke123

  • Newbie
  • Posts: 2
harvoni relapse
« on: February 13, 2016, 07:09:39 pm »
My mom was undetected at 12 weeks , unfortunately she relapse when she retested at 3 months. She has genotype 4 and has cirrhosi . She also has a low white cell count Anyone know if there is other treatments she should consider moving forwar . Now that harvoni had failed her I'm beginning to loose hope.

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,545
  • Get tested, get treated, get cured, fight Hep c!
Re: harvoni relapse
« Reply #1 on: February 14, 2016, 03:16:31 am »
Hi melke123

So sorry to hear about your moms situation.

Unfortunately, there is not a lot of data for those who relapse with Harvoni as the treatment is so new.

The best person to ask is her doctor. As she has cirrhosis I hope she is under the care of a hepatologist associated with a liver transplant center as they are best equipped the help and counsel a patient with advanced liver disease.

There was a newer treatment just approved for hep c that treats several genotypes one being genotype 4.

Here is the link for the prescribing information sheet


This may be an option for you mom but that is up to her doctor to make that determination.

I just want to add that I have been living with liver cirrhosis for 8 years. With care a person can live many years with cirrhosis as long as hey don't drink are careful with all medicine to include herbal and OTC meds and is followed closely by their doctor and has their recommended follow up testing done.

Good luck to you both
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!

Offline Mike

  • Member
  • Posts: 999
Re: harvoni relapse
« Reply #2 on: February 14, 2016, 01:45:36 pm »
Hi Melke123,

Very sorry to hear about your mother. There are new treatments coming out that target GT4.

Best wishes, Mike
Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014


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