Welcome, Guest. Please login or register.
May 26, 2024, 11:41:46 am

Login with username, password and session length


Members
  • Total Members: 6309
  • Latest: Vicki
Stats
  • Total Posts: 55126
  • Total Topics: 4851
  • Online Today: 98
  • Online Ever: 1314
  • (June 22, 2016, 05:23:42 am)
Users Online
Users: 0
Guests: 35
Total: 35

Welcome

Welcome to the Hep Forums, a round-the-clock discussion area for people who have Fatty Liver Disease, Hepatitis B, C or a co-infection, their friends and family and others with questions about hepatitis and liver health. Check in frequently to read what others have to say, post your comments, and hopefully learn more about how you can reach your own health goals.

Privacy Warning: Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.
  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.
  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.
  • Product advertisement (including links); banners; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from the Hep Forum Moderators.
Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: Starting a trial of Sof/velpatasvir(gs-5816)/gs-9857!  (Read 8601 times)

0 Members and 1 Guest are viewing this topic.

Offline tkflex36

  • Member
  • Posts: 30
Starting a trial of Sof/velpatasvir(gs-5816)/gs-9857!
« on: December 16, 2015, 10:43:18 am »
So I have been waiting for this trial for close to a year and it's finally happening! The trial will compare 8 weeks of sof/vel/gs9857 vs. 12 weeks of sof/vel amongst all genotypes. I am a 3a, but the phase 2 studies of these meds look great for everyone. It's an open label study with a study locations all over the world, I will know on day 1 which arm I will be in. I ho for screening on Mon the 21st. I have had no prior tx as insurance denied multiple times over the past year for sof/riba. I almost gave up and was just about to try and import the generics from China when university of Pennsylvania called about the trial. I feel truly blessed to have this chance, also nervous beings I've never done anything like this. But more then that I feel humbled knowing how many people need these meds and can't get them. I've been trying as of late to help educate others that insurance isn't the only way to get treatment anymore. I plan on starting a new thread when I actually start taking the meds in the "on tx" section to help give people an idea of how some of the newest drugs are working, and look forward to any advice I can get about being a trial participate from others who have already gone this route.
Much Love,
TK
Geno 3A, dx in 2001, 34 years old
Pre tx labs 12/21/15
VL 507,000
ALT 96
AST 136
Started trial of sovaldi and velpatasvir on 1/6/16
Week one blood work 1/13/16
VL  <15 detected
Alt-22
Ast-17
Week 4-2/3/16...VL-UNDETECTED
*don't stop fighting til the dragon is dead*

Offline jakas

  • Member
  • Posts: 265
Re: Starting a trial of Sof/velpatasvir(gs-5816)/gs-9857!
« Reply #1 on: December 16, 2015, 11:39:23 am »
Great ,let us know how you get on. All the best !
M/57 yrs.
Contracted (Unknown) 10-20-30 yrs back ??
Treatment Naive
Geno 1a&1b
VL  17+ million
ALT 200+, AST 170+
Fibroscan F4 ( 26+ kpa ) on 8th Dec. 2105
Started Tx 11th Dec.2015 ( 12 wks. Gilead Harvoni)
7/1/2016 :Viral Load|<25 UND.
23/1/2016: ALT 34 , AST 35, ALP 143
8 week NO labs done
EOT:03.03.2016 ( 84 pills eaten )
ALT 26, ALP 124, BIL .54
V/L <25 UND E.O.T.
4 weeks E.O.T. V/L UND::: SVR 4
SVR 12 and  SVR 24 on 16/8/16
Fibro 24.5kpa 23/05/16
SVR 63 05/17
Fibro 17.03.2020 kpa 6.3

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Starting a trial of Sof/velpatasvir(gs-5816)/gs-9857!
« Reply #2 on: December 16, 2015, 12:50:26 pm »
Congrats TK! Sounds like a great trial for you. I was also 3a, and was cured earlier this year in a clinical trial of 12 wks Harvoni/ribavirin. That's great that you found a trial and are getting your drugs that way.

best,
kim :)
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline slats1056

  • Member
  • Posts: 765
  • SVR to all and to all a good life!
Re: Starting a trial of Sof/velpatasvir(gs-5816)/gs-9857!
« Reply #3 on: December 16, 2015, 12:56:20 pm »
 TK, Glad to know someone here on the forums is in on the ground floor. I am interested in the New med combo. It looks extremely promising.  Keep Us posted on how it goes. Very Happy for You, and waiting on future posts! :)
73 non ab 98 hep c refused pegint/riba
6-15 Gen.1b 1/2 MIL ALT72 AST37 No cirrhosis
7-15  Harvoni 12 weeks
10-14-15 EOT VIRAL LOAD NON-DET  
12-30-15 EOT+12 VIRAL LOAD NON DET  SVR12            8-9-18 HCV LOAD 1.02IU/ml AST22  ALT30 RELAPSE?
9-18-18 confirmed gt 1b relapse
10-16-18 approved 16 weeks Mavyret

Offline tkflex36

  • Member
  • Posts: 30
Re: Starting a trial of Sof/velpatasvir(gs-5816)/gs-9857!
« Reply #4 on: December 21, 2015, 09:21:35 pm »
So I went in for the screening process today, and after 12 tubes of blood, an ekg, and a urine test, I was done. They should have all the results by the end of the week and if all goes well I should be starting tx by middle of next week!
Geno 3A, dx in 2001, 34 years old
Pre tx labs 12/21/15
VL 507,000
ALT 96
AST 136
Started trial of sovaldi and velpatasvir on 1/6/16
Week one blood work 1/13/16
VL  <15 detected
Alt-22
Ast-17
Week 4-2/3/16...VL-UNDETECTED
*don't stop fighting til the dragon is dead*

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Starting a trial of Sof/velpatasvir(gs-5816)/gs-9857!
« Reply #5 on: December 21, 2015, 09:48:54 pm »
Way to go, Tk! That's great. :)

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

 


© 2024 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.