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Author Topic: Drink Coffee to Help Prevent Liver Fibrosis  (Read 13532 times)

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Offline Hep Editors

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    • Hep Mag
Drink Coffee to Help Prevent Liver Fibrosis
« on: November 30, 2015, 01:52:59 pm »
Researchers recently found that people with hepatitis C who drank two or more daily cups of coffee had a 13 percent reduced rate of liver stiffness, or fibrosis compared to those who didn't drink a daily brew. 

What's more, people with hep B and NAFLD who consumed four or more cups of coffee daily also had a respective 18 and 24 percent reduction in their liver stiffness.

For more info on how and why this might happen, read here: http://www.hepmag.com/articles/coffee_fibrosis_2501_28099.shtml

Offline gnatcatcher

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #1 on: November 30, 2015, 03:37:55 pm »
For those of us (a small minority, I realize) who hate the taste of coffee, is there any way to get the benefit without having to drink 16 ounces per day? Milk/cream &/or sugar make it taste even worse, and mocha added to anything ruins it. Are the active ingredient(s) in any sort of pill? Thanks.

Gnatty
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline KimInTheForest

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #2 on: November 30, 2015, 06:47:56 pm »
I wonder what it is in the coffee that accounts for this? When I was diagnosed with HCV 20 years ago, I immediately switched from coffee to tea, thinking I was helping my liver by reducing my caffeine intake. I had read that caffeine is metabolised by the liver, so why not help reduce the liver's workload, I thought. Since switching for tea, I have totally lost my taste for coffee and really don't enjoy drinking it. Any chance that the magic anti-fibrosis ingredient in coffee is also in black tea?

I am glad I no longer have HCV. But I would like to do anything to help my liver reverse the fibrosis, which from what I am reading is entirely possible. :)

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline KimInTheForest

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #3 on: November 30, 2015, 06:52:39 pm »
apparently it is not yet known which ingredient in coffee is the miracle-worker. From the original article:

"It is not yet known whether these benefits are related to caffeine or other components of coffee such as antioxidants or other phytochemicals. Some studies suggest caffeine and other chemicals in coffee may dampen inflammation and reduce collagen production."

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Mugwump

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #4 on: November 30, 2015, 06:59:05 pm »
I would attribute having a softer liver by drinking 4 cups of starbucks to the well documented "bouncing off the walls" effect.
Caution shameless self promotion below :-)
https://www.hepmag.com/article/eric-reesor-27742-782589663
DING DONG MY DRAGON (HCV) IS FINALLY DEAD!

Offline gnatcatcher

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #5 on: November 30, 2015, 07:33:38 pm »
Thanks to both of you -- Kim for reading more thoroughly than I did, and Eric for the great laugh. This is at least the third time I've seen a post by the Hep editors extolling the virtues of coffee, and each time I've tried it again, then posed this hypothetical to myself: Given a choice between having to swallow 730 cups of this stuff per year or living a shorter life, which would you choose? Obviously, by my behavior I've chosen the latter :P

If it's the antioxidants, quite a few high-antioxidant foods are among my favs. I manage to get quite a lot of phytochemicals in my diet, too. And for caffeine, there's always chocolate ;)  So maybe I'm pretty well covered after all.

Gnatty

P.S. Black tea is high in caffeine, so if that's it, you're well covered too, Kim, as long as you drink four cups/day: http://nutritiondata.self.com/foods-000131000000000000000.html
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline MaryC

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #6 on: November 30, 2015, 08:11:12 pm »
Interestingly...I have always had 1.5 cups of coffee in the morning - for the last 30 + years.   That is all I ever wanted or needed, and never craved (or wanted) more, and never, ever have a desire to drink it after breakfast.  Since starting my medications, however, things have been different.  I have noticed I increasingly looked forward to my morning java.  In fact...my consumption has doubled to 3 cups in the morning.  I am also craving it well past breakfast though have resisted the urge drink it later in the day as I worry it will interfere with sleep.  Just curious if anyone else has experienced this phenomenon also?  I can't help but wonder if it is somehow related to my meds.  Possibly I do feel more fatigued (and haven't noticed it) and am trying to counteract with the extra caffeine?? 
Mary
GT 3a
Dx'd 4/15 not known when contracted
Labs 7/15:
-VL 537,000
-AST 32
-ALT 41
-Fibrosis score 0.46 (F1-F2)
Started tx 9/17/2015 with Daklinza + Sovaldi
6/6/16: 24 week EOT SVR!  Cured!

Offline The Terminator

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #7 on: December 12, 2015, 08:11:56 pm »
pour a up of coffee look into the cup you will see what looks like a lite film swirling around that is riboflavin believe years ago when reserched its a protein/antioxident idrink two cups aday on harvoni, doesnt bother me,but some people might respond differently to it

Offline jakas

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #8 on: December 13, 2015, 04:18:13 am »
In my country we are one of the heaviest coffee drinkers in the world. I was drinking 6-8 cups a day. Cut down a bit now.
IMHO I dont really believe it helps
M/57 yrs.
Contracted (Unknown) 10-20-30 yrs back ??
Treatment Naive
Geno 1a&1b
VL  17+ million
ALT 200+, AST 170+
Fibroscan F4 ( 26+ kpa ) on 8th Dec. 2105
Started Tx 11th Dec.2015 ( 12 wks. Gilead Harvoni)
7/1/2016 :Viral Load|<25 UND.
23/1/2016: ALT 34 , AST 35, ALP 143
8 week NO labs done
EOT:03.03.2016 ( 84 pills eaten )
ALT 26, ALP 124, BIL .54
V/L <25 UND E.O.T.
4 weeks E.O.T. V/L UND::: SVR 4
SVR 12 and  SVR 24 on 16/8/16
Fibro 24.5kpa 23/05/16
SVR 63 05/17
Fibro 17.03.2020 kpa 6.3

Offline Philadelphia

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #9 on: December 13, 2015, 04:39:36 am »
What country are you from Jakas?
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Flaco

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #10 on: January 20, 2016, 09:29:53 pm »
Well, I hope that includes decaf. I love coffee but had to give up the real thing when I noticed it elevated my blood sugar, and I drink it black, or sometimes with a touch of stevia.
Best Regards,
Jack

Diag 2001
Failed PEG-int/Riba 2002, 48 wks.
2015-16:
F4 compensated
VL 14.7 million
GT 1A
Alkaline Phosphatase(37-127 U/L): 12/23/15 216; 1/14/16 152; 1/29/16 103; 3/18/16 68; 4/1/16 70
SGPT (ALT) (15-78 U/L) 12/23/15 862; 1/15/16 753; 1/29/16 518; 3/18/16 48; 4/1/16 28
SGOT (AST) (9-44 U/L) 12/23/15 283; 1/15/16 226; 1/29/16 165; 3/18/16 24; 4/1/16 19
Start Harv 24 wks. 3/4/16
Undetected 2 weeks into Tx
Liver&metabolic nos. steadily improving since start TX
EOT 8/18/16

Offline dragonslayer

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #11 on: January 24, 2016, 10:05:38 am »
Well, I hope that includes decaf. I love coffee but had to give up the real thing when I noticed it elevated my blood sugar, and I drink it black, or sometimes with a touch of stevia.

I've never heard or read that black coffee without sugar effects blood sugar level. .Do you have a link to any research?

As far as decaf goes, the studies Ive read indicate it does not have a similar effect to regular coffee with regard to fibrosis, nor do other caffeinated drinks.
« Last Edit: January 24, 2016, 10:07:36 am by dragonslayer »
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline Flaco

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #12 on: January 24, 2016, 10:23:21 am »
Well, I just woke up, but this is the first study I came to by googling caffeine and diabetes.
There are many other articles.
Bummer about the decaf and fibrosis. :( Interesting thing is that you indicate it's not the caffeine itself. Apparently the decaffeinating process removes more than just caffeine.
« Last Edit: January 24, 2016, 10:28:57 am by Flaco »
Best Regards,
Jack

Diag 2001
Failed PEG-int/Riba 2002, 48 wks.
2015-16:
F4 compensated
VL 14.7 million
GT 1A
Alkaline Phosphatase(37-127 U/L): 12/23/15 216; 1/14/16 152; 1/29/16 103; 3/18/16 68; 4/1/16 70
SGPT (ALT) (15-78 U/L) 12/23/15 862; 1/15/16 753; 1/29/16 518; 3/18/16 48; 4/1/16 28
SGOT (AST) (9-44 U/L) 12/23/15 283; 1/15/16 226; 1/29/16 165; 3/18/16 24; 4/1/16 19
Start Harv 24 wks. 3/4/16
Undetected 2 weeks into Tx
Liver&metabolic nos. steadily improving since start TX
EOT 8/18/16

Offline dragonslayer

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #13 on: January 24, 2016, 11:27:28 am »
Thanks for that blood sugar info.. I wasnt aware.  Regarding caffeine and its utility in mitigating liver fibrosis, what Ive read is that theyre really not sure what it is about coffee that causes this beneficial effect; its possible that caffeine plays some part in the process, but it seems to be more complicated than just popping caffeine pills would indicate.
« Last Edit: January 24, 2016, 11:33:27 am by dragonslayer »
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline beto

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #14 on: January 24, 2016, 12:20:34 pm »
I've never heard or read that black coffee without sugar effects blood sugar level. .Do you have a link to any research?

As far as decaf goes, the studies Ive read indicate it does not have a similar effect to regular coffee with regard to fibrosis, nor do other caffeinated drinks.

Caffeine does raise some corticosteroids, and can raise cortosol   levels, which can cause the body to produce glucose from glycogen stores (or so I've read)...That said, I have been aware of information regarding the positives liver benefits of coffee, and one report I read did say decaffeinated was not as effective.   Part of the alternative use of coffee enemas (Gerson, etc) was this believed benefit.  I love coffee, so...nice to think it may help.  I do believe it does raise my blood pressure though which is a struggle for me.
HCV/nonA,nonB acute phase 1975
HCV detected active 1990
HCV persistent chronic diagnosis 1995
1995 liver enzymes mild elevations
1996 Biopsy F2 fibrosis
treatment naive geno 1-A
2000-to early 2015 Viral load 150, 000 to 800, 000
recent liver enzymes before treatment alt/ast 59to209,  Fibroscan F4,cirrhosis
start tx Harvoni 7/11/2015
6.5 week-UD-ast/alt 25/25
9wk-UD-ast18 alt23
10/3/15 completed tx
11/5/15 new fibroscan f0-f1 amazed
6wk EOT UD ast/alt 20/20
12EOT-UD-ast/alt19/21
25wk-SVR! 19/18

Offline Mugwump

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Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #15 on: January 24, 2016, 10:45:11 pm »
Caffeine does raise some corticosteroids, and can raise cortosol   levels, which can cause the body to produce glucose from glycogen stores (or so I've read)...That said, I have been aware of information regarding the positives liver benefits of coffee, and one report I read did say decaffeinated was not as effective.   Part of the alternative use of coffee enemas (Gerson, etc) was this believed benefit.  I love coffee, so...nice to think it may help.  I do believe it does raise my blood pressure though which is a struggle for me.

Don't forget that the production and conversion of usable glucose is done by the liver. So you can have a hard time with caffeine if you are diabetic because after taking a shot of insulin you can become hypoglycemic later on after taking insulin because over the period of a few hours the liver has run short of fast available glycogen stores. Most stimulants in the class of caffeine cause the liver to use up more sugar and is the reason why you get a sudden burst of a "speed jag" out of caffeine in the first place.

The same way that you can very quickly become hypoglycemic by drinking alcohol, which prevents the liver from converting glucose and is the reason why you quickly become intoxicated. Which in turn is just a sudden impediment to sugars that feed the brain. Then later on after you are finished drinking you can experience the wonderful effects of a hangover which is essentially more advanced hypoglycemia and is part of the reason why so many teenagers and children are more easily killed by the unrestrained consumption of alcohol.
« Last Edit: January 24, 2016, 10:46:47 pm by Mugwump »
Caution shameless self promotion below :-)
https://www.hepmag.com/article/eric-reesor-27742-782589663
DING DONG MY DRAGON (HCV) IS FINALLY DEAD!

Offline Flaco

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  • Posts: 56
Re: Drink Coffee to Help Prevent Liver Fibrosis
« Reply #16 on: January 25, 2016, 09:08:12 am »
Regarding caffeine and its utility in mitigating liver fibrosis, what Ive read is that theyre really not sure what it is about coffee that causes this beneficial effect; its possible that caffeine plays some part in the process,[snip]
...and let us not forget the buzz of a few years ago that coffee may delay (or prevent?) the onset of type 2 diabetes. http://coffeeandhealth.org/topic-overview/coffee-consumption-and-type-2-diabetes/
Interestingly, decaf is included in this article:
Quote
Decaffeinated coffee and tea and risk of type 2 diabetes
As with caffeinated coffee, the majority of published studies which have evaluated the relationship between decaffeinated coffee or tea drinking and risk of type 2 diabetes have reported similar negative associations.
A bit off topic, I'm afraid, but I thought it was interesting. Just based on that article (and I admit I have not looked at others) it appears that coffee and tea, decaf or not, may benefit the liver in numerous ways. Still, the above-referenced article mentions drinking a LOT of coffee or tea, what would seem (to me at least) to be way beyond the limit of "moderation." What side effects might that have?
Best Regards,
Jack

Diag 2001
Failed PEG-int/Riba 2002, 48 wks.
2015-16:
F4 compensated
VL 14.7 million
GT 1A
Alkaline Phosphatase(37-127 U/L): 12/23/15 216; 1/14/16 152; 1/29/16 103; 3/18/16 68; 4/1/16 70
SGPT (ALT) (15-78 U/L) 12/23/15 862; 1/15/16 753; 1/29/16 518; 3/18/16 48; 4/1/16 28
SGOT (AST) (9-44 U/L) 12/23/15 283; 1/15/16 226; 1/29/16 165; 3/18/16 24; 4/1/16 19
Start Harv 24 wks. 3/4/16
Undetected 2 weeks into Tx
Liver&metabolic nos. steadily improving since start TX
EOT 8/18/16

 


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