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Author Topic: EOT lab results from Harvoni  (Read 7161 times)

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Offline LeslieR1234

  • Member
  • Posts: 4
EOT lab results from Harvoni
« on: May 18, 2016, 10:25:05 am »
Hi All
I just completed treatment with Harvoni in April 2016. Tested one week after completion of treatment. HCV still undetected but my ALT and AST's are a bit elevated. My Dr. told me not to worry about it, but of course I am. Anyone else have this experience? I am so worried that I may be the 2 percent that wont respond.
Logged
LeslieR
Genotype 1A
Diagnosed 1985 Hep C
Fibrospect F2-F4
HCV RNA 875,000
Treatment Naive
Started Harvoni 1/27/16
Lab Results on 3/1/16
HCV Viral load, undetected.
ALT just 5 points over range (all labs have been abnormal for the past 25 years)
EOT lab results HCV undetected
ALT and AST slightly elevated .

Offline brie41

  • Member
  • Posts: 191
Re: EOT lab results from Harvoni
« Reply #1 on: May 18, 2016, 11:16:20 am »
Hi Leslie,

  I finished my 8 week harvoni treatment on May 9th.  My Alt and Ast were always in the mid 20's but they went down in the teens once on treatment.  But my 8 week test showed my alt I think was back in the 20's.  I don't think it means anything.  I noticed that a lot of people who post here have higher levels and they are svr.  It is easy to worry for sure.  I am noticing a decrease in energy, and just some other weird symptoms that of course put the thought in my head that it may be back.  But then I stop that and keep thinking positive, or in our case Negative thoughts!! Hang in there and good luck!  Brie
Logged
Diagnosed  HCV, 1A 2006
Viral load 6 million
Ast/Alt always in the 20's
F0-F1, never changed
Treatment naive, started 8 week Harvoni 3/15/16
4 and 8 week labs undetected
6 week eot labs undetected
13 week eot UNDETECTED!

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: EOT lab results from Harvoni
« Reply #2 on: May 18, 2016, 01:16:30 pm »
Leslie, "a bit elevated" is not unusual. Look below and you'll see that my numbers did some jumping around, but I remained cured 24 weeks after I finished the Harvoni. People who relapsed saw huge increases.

Like Brie, I had a decrease in energy post-Tx. It also didn't mean anything.

Sending good thoughts,

Gnatty
Logged
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline FutureThinker

  • Member
  • Posts: 711
  • Onward and upward!
Re: EOT lab results from Harvoni
« Reply #3 on: May 18, 2016, 02:02:23 pm »
Leslie, I'm right there with you, this is my first day w/o Harvoni.  I won't know my EOT lab results until later in the week or next week.  I think we just need to try very hard to try to get on with our lives again, as life is short. We will get SVR hopefully, but worrying about it isn't going to help with the next test.  Let's try to take a deep breath with we start to worry and focus on good, positive aspects of our lives -- we got thru HCV treatment, for one! I am so very happy it's completed! We need to try to be positive and focus on our lives again, if at all possible.  Wishing you the best in this "waiting" time ---- FT
Logged
Treatment naive
Likely contracted mid-70s
Diagnosed 1a, 2011
F1-2
Harvoni X 12 weeks, completed 5/17/16
Pre-treatment: VL 3 mil, AST 64, ALT 84
4 week labs: VL 30, AST 21, ALT 14
8 week labs: VL UD!!!, AST 22, ALT 16
12 week labs: VL UD, AST 23, ALT 14
2 wk EOT: VL UD
12 wk EOT: VL UD, AST 22, ALT 13 =  SVR 12! Yay! 
Last hep appointment: VL UD, AST 19, ALT 12 = SVR 39! I AM DONE!

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: EOT lab results from Harvoni
« Reply #4 on: May 18, 2016, 08:33:19 pm »
Liver enzyme tests fluctuate probably hourly. Were they still in normal range?

If they get above normal range and especially if they get back to what they were before treatment that would have me raise an eyebrow. Otherwise just normal fluctuation

Congrats on finishing treatment and good luck
Logged
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!
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