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Author Topic: For RELAPSERS...What was your EOT VL and what week afterwards did you relapse  (Read 6531 times)

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Offline JackN

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  • Posts: 52
Curious. For relapses,
(1) what week did you go non detected?
(2) what was your EOT VL?
(3) what week did you relapse?
Thanks for any data.  For myself I'm trying to determine if me clearing the virus slowly is an advantage or disadvantage.
Likely infected 1970's
VL 575,000
Liver Functions normal (ALT/AST)
F0 Fibroscan
Started Harvoni 12-5-15
4week labs 63 VL
6week labs 21 VL
2-17-16 NONDETECTED :) prior to 12 week EOT
3-28-16 EOT 4 week testing = nondetected
5-11-16 EOT 10 week testing = nondetected

Offline Lynn K

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  • Get tested, get treated, get cured, fight Hep c!
Hi on treatment viral load matters little

I treated from March to June 2014 with Sovaldi and Olysio

I was not detected at week 4 and at end of treatment (EOT) week 12 I was still not detected. When tested again in September 2014 my viral load had returned to slightly higher than pre treatment level at 2.4 million with before treatment was 2 million.

We have even had s few here who were weakly detected at EOT who later made SVR 12

The only test that counts is the 12 week post treatment test.

Good luck the odds of cure for you are very good as they are for most of us

Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!

Offline Philadelphia

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  • It only looks like I know what I'm doing
Hi Jack, although I cleared the virus and was undetectable at EOT12, I was slow to clear the virus, not getting a UND on treatment till somewhere between 4 and 8 weeks. Lynn is right, it's the numbers at the end that matter.
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013


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