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Author Topic: Milk Thistle  (Read 7346 times)

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Offline BillT

  • Member
  • Posts: 573
Milk Thistle
« on: March 05, 2016, 06:39:32 pm »
I'm post tx now and I'm curious if anyone else is taking milk thistle.I started at the beginning of the month after doing a lot of research on it and it seems like it's effective.Right now I'm taking 175mg x3,but I've seen where some people are taking 1000mg x2.Everything I've read about it is positive.Has anyone had any experience with it?
« Last Edit: March 05, 2016, 06:46:45 pm by BillT »
Contracted 1973 Military
Diagnosed 1980
Pegintron treatment 2004 unsucessful
Genotype 1b
FibroScan 10 (F2)
Start Viekira 10.17.2015

AST 40 ALT 69
VL 440k
10.31.2015/Week 2 Labs : AST 14/ALT 17
No VL done
10.14.2015/Week 4 labs : AST 14/ALT 14
VL UNDETECTED!!!
12.11.2015/Week 8 Labs : AST 12/ALT 13
No VL done
01.05.2016/EOT labs : AST 15/ALT 13
VL UNDETECTED!!!

12 WEEK SRV:UN-BLOODY DETECTABLE !!!!!!!!

24 WEEK SVR:UNDETECTABLE!!!! Thank You God.

Fibroscan 6Mo. Post Treatment 7.15.2016-5.3(F1)

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: Milk Thistle
« Reply #1 on: March 05, 2016, 07:04:25 pm »
I haven't seen anything with conclusive evidence of effectiveness. Most everything I have seen says no conclusive evidence. All I am sure of is it should not harm you.
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline CureSeeker

  • Member
  • Posts: 121
  • Virus Free! Happy Dance Time!
Re: Milk Thistle
« Reply #2 on: March 05, 2016, 08:26:03 pm »
I tried it once a few years prior to treatment, but didn't feel like it was doing anything.

I'm sort of a supplement junkie who right now feels like she has been taking far too many, lol. 

Anyway, if you feel its helping you, and your Doctor doesn't have any issues with it, go for it.
Once you eliminate the impossible, whatever remains, no matter how improbable, must be the truth.

~ Arthur Conan Doyle


Genotype 3a, F 0-1
Sovaldi & Ribavirin x 24 weeks

2/23/16 - UNDETECTED!  SVR12 achieved.  :D
6/21/17 - UNDETECTED!  1.5 years post treatment.
July 2018 - UNDETECTED!

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: Milk Thistle
« Reply #3 on: March 05, 2016, 09:18:46 pm »
From NCBI Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical Adverse Effects: Summary

http://www.ncbi.nlm.nih.gov/books/NBK11896/

Conclusions

Clinical efficacy of milk thistle is not clearly established. Interpretation of the evidence is hampered by poor study methods and/or poor quality of reporting in publications. Problems in study design include heterogeneity in etiology and extent of liver disease, small sample sizes, and variation in formulation, dosing, and duration of milk thistle therapy. Possible benefit has been shown most frequently, but not consistently, for improvement in aminotransferases and liver function tests are overwhelmingly the most common outcome measure studied. Survival and other clinical outcome measures have been studied least often, with both positive and negative findings. Available evidence is not sufficient to suggest whether milk thistle may be more effective for some liver diseases than others or if effectiveness might be related to duration of therapy or chronicity and severity of liver disease. Regarding adverse effects, little evidence is available regarding causality, but available evidence does suggest that milk thistle is associated with few, and generally minor, adverse effects.
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Mugwump

  • Member
  • Posts: 778
  • My number of posts means nothing, piscor ergo sum!
Re: Milk Thistle
« Reply #4 on: March 06, 2016, 08:20:14 pm »
Canada thistle is edible and quite good to eat, if you know how to use it as a food. I would be more inclined to include the plant in my diet the same way you see some Italian immigrants harvesting  dandelions for the table. The plant root and lower stem is delicious if prepared right.

During the years after my failed interferon tx I ate it. Also I harvested overripe West Coast Baldhip rose buds and made teas and added the skins to my diet. I made jellies and drinks out of berries from dull Oregon grape.

Whether or not any of this helped? I doubt it. But the logic of what I did was there because overripe Baldhip rose buds create variations of xylitol similar to ones that are prescribed in Norway by doctors for difficult cases of bilious colds and flue. West Coast Natives used it for thousands of years to fight colds and flue. And also used the Oregon grape plant to treat jaundice. How and how much is anyone's guess. And this is the problem.

Trusting the sketchy products that are peddled as pills at ridiculous prices for products which do not even have standardized production methods or testing only promotes the snake oil salesmen IMO.

There are a few companies who are more reliable with the information that they put on their pill bottles but by and large the claims made are nebulous with claims that include words like "cleanse the blood and liver" and other holistic catch phrases that mean absolutely squat!

Sorry I just do not trust them and I doubt I ever will.

Eric

 
« Last Edit: March 06, 2016, 08:21:45 pm by Mugwump »
Caution shameless self promotion below :-)
https://www.hepmag.com/article/eric-reesor-27742-782589663
DING DONG MY DRAGON (HCV) IS FINALLY DEAD!

Offline HazelAustralia

  • Member
  • Posts: 178
Re: Milk Thistle
« Reply #5 on: March 06, 2016, 09:32:11 pm »
I agree that supplements are like the 'fast food' of food sometimes. I believe that globe artichokes have the same nutrient as milk thistle as well as the bitter greens that mugwump mentions (radicchio, dandelion, sticky-weed, endive, arugula). I don't know of any research but I do think that the bitter taste is good for the liver. The rosehips have definitely been shown to have lots of vitamin c and they are delicious and free! Can be made into a cool drink too. All in moderation.
Female age 53
Australia
Contracted in the 1980's
Genotype 1A
VL 314k

Started treatment with Veikira Pak and Ribaviron on Thursday 17th December 2015
NOT DETECTED, End of Treatment, 16th March 2016

 


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