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Author Topic: Vitamin D defeciency  (Read 11317 times)

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Offline drummerman

  • Member
  • Posts: 538
  • For those regarded as warriors....
Vitamin D defeciency
« on: June 03, 2016, 08:24:53 pm »
As some of you know i have a vitamin D deficiency and have started on rx vit D supplements.

Seems to be working as I don't have as much muscle tiredness, doc wants to recheck vitamin D levels at end of July.

I highly recommend that you get your levels checked.  Also, this is a great, eye opening video.  Apparently this is a problem in many countries.
http://www.ucsd.tv/search-details.aspx?showID=29085

Also, I keep seeing many , many people on the internet with vitamin D deficiencies AND high WBC (which I also have)  but I can't find any studies or correlations between the two.... except for one article that suggests it is due to thyroid problems.

weird.

dm
« Last Edit: June 03, 2016, 09:32:47 pm by drummerman »
Logged
Diagnosed07
Interferon/riba 2008 - non-responder
5/16/15 - AST -34
ALT - 35_ HCV RNA - 10,783,000
 7/6/15 - started viekira/riba
8/11/15  Week 5 <15 vl,  AST 18, ALT 18
9/11/15 Week 9  "HCV NOT DETECTED"!
AST 16, ALT 11.  10/16/16 - 2 weeks post EOT = "HCV NOT DETECTED!   AST - 18,  ALT 14
12/29/15 -12 wk EOT-HCV NOT DETECTED! AST 23, ALT 15
3/26/16 - 24 wk post EOT - HCV NOT DETECTED!! AST 19, ALT 21
1 yr eot - AST 20, ALT 17

Offline slats1056

  • Member
  • Posts: 765
  • SVR to all and to all a good life!
Re: Vitamin D defeciency
« Reply #1 on: June 06, 2016, 08:50:09 am »
 Hey DM,

  Pluggin' for Ya big guy! Right there behind You. My re-check is in September. Strange how all of these anamolies keep popping up. But ,onward through the fog. Don't remember the WBC numbers on My latest Labs , but will check My file anyway.
  Not only was I Vit D deficient ( low end 30 & I was 17 ) , but had low Vit B levels as well. Need to check more into MINERAL levels also.

 Good luck and good to hear from You.
                                             Tommy
Logged
73 non ab 98 hep c refused pegint/riba
6-15 Gen.1b 1/2 MIL ALT72 AST37 No cirrhosis
7-15  Harvoni 12 weeks
10-14-15 EOT VIRAL LOAD NON-DET  
12-30-15 EOT+12 VIRAL LOAD NON DET  SVR12            8-9-18 HCV LOAD 1.02IU/ml AST22  ALT30 RELAPSE?
9-18-18 confirmed gt 1b relapse
10-16-18 approved 16 weeks Mavyret

Offline rabbitfluff

  • Member
  • Posts: 4
Re: Vitamin D defeciency
« Reply #2 on: June 06, 2016, 11:34:53 am »
I swear by Vitamin D supplements. I was checked a few years ago and had low levels, and since taking supplements (D3 because it's the easiest to metabolize) I've had regular levels. I had it explained to me that Vitamin D is used up super quickly when the body has an infection, like a cold or wound or, yes, Hep C. With this chronic infection, our Vitamin D stores are being tapped into all the time and I think we're more likely to have low levels. This is completely speculation, and I don't really have the science to back it up, but it makes sense to me!

[Randon Vit D info just for fun] I've also been told that when we have low levels of Vitamin D we're more likely to get sunburned, because the body is actively trying to suck up Vit D when we're exposed to the sun. With higher internal levels, our body stops trying to suck up every bit of sunlight and it's harder to get sunburned.
Logged

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Vitamin D defeciency
« Reply #3 on: June 06, 2016, 11:46:50 am »
I too am taking vitamin D supplements. My level 5 weeks post-treatment was 104 nmol/L (reference range: 75-150). So I wasn't subnormal, but I would like it higher.

I have read that Vitamin D is best taken with a meal, and ideally a fatty meal for best absorption. So that's what I've been aiming for. I am taking liquid D3 from a dropper.

I also read that those hit hardest by ribavirin anemia were also low in Vitamin D. That's why I decided to have my Vit. D checked in the first place.

I have not had it rechecked in the intervening months. Would be interesting to see if supplements have raised it. The test costs me $60.

kim
Logged
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Gaj

  • Member
  • Posts: 172
  • Optimist
Re: Vitamin D defeciency
« Reply #4 on: June 06, 2016, 07:32:21 pm »
Hi all,

Below is a link to an interesting study regarding Vitamin D levels. It does seem to show correlation between HCV infection and low levels. They also found improved SVR rates for those with good (>30ng/mL or 75nmol/L) vitamin D levels at least when treating with interferon.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793147/

But please keep in mind that excessive levels of vitamin D can cause problems so you should only consider supplements based on testing and medical advice.

« Last Edit: June 06, 2016, 07:41:35 pm by Gaj »
Logged
Male - 61 years
Genotype 3a (since 1978?)
Diagnosed 2012
Treated 2013 PEG/Riba/Dac (Relapsed)
F4 - HCC#1 Resected 06/15 - #2 RFAblated 11/15
11/18/15 Commenced Generic Tx - Sof/Dac/Riba (24wks)
Pre Tx = ALT: 270  AST: 209  ALB: 31
05/05/16 = ALT: 34  AST: 32  ALB: 40  VL: Undetected (EOT)
06/16/16 = Relapsed
06/23/16 = ALT: 92  AST: 59  ALB: 40  VL: 290,770
01/12/17 3rd Tx - Zepatier + Sofosbuvir (16wks)
05/03/17 EOT und
06/22/17 SVR7 und
07/27/17 SVR12 UND!
10/26/17 SVR24 UND & Cured!!!

Offline beto

  • Member
  • Posts: 548
  • "no risk it, no biscuit"
Re: Vitamin D defeciency
« Reply #5 on: June 06, 2016, 07:57:31 pm »
just make sure to supplement with D3 not D2
Logged
HCV/nonA,nonB acute phase 1975
HCV detected active 1990
HCV persistent chronic diagnosis 1995
1995 liver enzymes mild elevations
1996 Biopsy F2 fibrosis
treatment naive geno 1-A
2000-to early 2015 Viral load 150, 000 to 800, 000
recent liver enzymes before treatment alt/ast 59to209,  Fibroscan F4,cirrhosis
start tx Harvoni 7/11/2015
6.5 week-UD-ast/alt 25/25
9wk-UD-ast18 alt23
10/3/15 completed tx
11/5/15 new fibroscan f0-f1 amazed
6wk EOT UD ast/alt 20/20
12EOT-UD-ast/alt19/21
25wk-SVR! 19/18

Offline drummerman

  • Member
  • Posts: 538
  • For those regarded as warriors....
Re: Vitamin D defeciency
« Reply #6 on: June 06, 2016, 09:16:09 pm »
Quote from: beto on June 06, 2016, 07:57:31 pm
just make sure to supplement with D3 not D2

True that ... but they both do a good job...D2 is absorbed more easily and the D3 you have to take everyday.  I'm going to finish my D2 and then go D3, bottle is here and ready to go.   Course the best vitamin D source is the sun.... but it has been cloudy here for months.  Finally got a few days of sunshine.

dm

« Last Edit: June 06, 2016, 09:59:36 pm by drummerman »
Logged
Diagnosed07
Interferon/riba 2008 - non-responder
5/16/15 - AST -34
ALT - 35_ HCV RNA - 10,783,000
 7/6/15 - started viekira/riba
8/11/15  Week 5 <15 vl,  AST 18, ALT 18
9/11/15 Week 9  "HCV NOT DETECTED"!
AST 16, ALT 11.  10/16/16 - 2 weeks post EOT = "HCV NOT DETECTED!   AST - 18,  ALT 14
12/29/15 -12 wk EOT-HCV NOT DETECTED! AST 23, ALT 15
3/26/16 - 24 wk post EOT - HCV NOT DETECTED!! AST 19, ALT 21
1 yr eot - AST 20, ALT 17

Offline drummerman

  • Member
  • Posts: 538
  • For those regarded as warriors....
Re: Vitamin D defeciency
« Reply #7 on: June 06, 2016, 09:17:22 pm »
Quote from: Gaj on June 06, 2016, 07:32:21 pm
Hi all,

Below is a link to an interesting study regarding Vitamin D levels. It does seem to show correlation between HCV infection and low levels. They also found improved SVR rates for those with good (>30ng/mL or 75nmol/L) vitamin D levels at least when treating with interferon.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793147/

But please keep in mind that excessive levels of vitamin D can cause problems so you should only consider supplements based on testing and medical advice.

Thanks for finding this study.  Makes perfect sense  , I knew there had to be a correlation.

Watch the presentation.   Its practically impossible to achieve toxic levels of Vitamin D.

dm
Logged
Diagnosed07
Interferon/riba 2008 - non-responder
5/16/15 - AST -34
ALT - 35_ HCV RNA - 10,783,000
 7/6/15 - started viekira/riba
8/11/15  Week 5 <15 vl,  AST 18, ALT 18
9/11/15 Week 9  "HCV NOT DETECTED"!
AST 16, ALT 11.  10/16/16 - 2 weeks post EOT = "HCV NOT DETECTED!   AST - 18,  ALT 14
12/29/15 -12 wk EOT-HCV NOT DETECTED! AST 23, ALT 15
3/26/16 - 24 wk post EOT - HCV NOT DETECTED!! AST 19, ALT 21
1 yr eot - AST 20, ALT 17

Offline drummerman

  • Member
  • Posts: 538
  • For those regarded as warriors....
Re: Vitamin D defeciency
« Reply #8 on: June 06, 2016, 09:20:34 pm »
Quote from: rabbitfluff on June 06, 2016, 11:34:53 am
I swear by Vitamin D supplements. I was checked a few years ago and had low levels, and since taking supplements (D3 because it's the easiest to metabolize) I've had regular levels. I had it explained to me that Vitamin D is used up super quickly when the body has an infection, like a cold or wound or, yes, Hep C. With this chronic infection, our Vitamin D stores are being tapped into all the time and I think we're more likely to have low levels. This is completely speculation, and I don't really have the science to back it up, but it makes sense to me!

[Randon Vit D info just for fun] I've also been told that when we have low levels of Vitamin D we're more likely to get sunburned, because the body is actively trying to suck up Vit D when we're exposed to the sun. With higher internal levels, our body stops trying to suck up every bit of sunlight and it's harder to get sunburned.

You're also more likely to be depressed.... I know.


dm
Logged
Diagnosed07
Interferon/riba 2008 - non-responder
5/16/15 - AST -34
ALT - 35_ HCV RNA - 10,783,000
 7/6/15 - started viekira/riba
8/11/15  Week 5 <15 vl,  AST 18, ALT 18
9/11/15 Week 9  "HCV NOT DETECTED"!
AST 16, ALT 11.  10/16/16 - 2 weeks post EOT = "HCV NOT DETECTED!   AST - 18,  ALT 14
12/29/15 -12 wk EOT-HCV NOT DETECTED! AST 23, ALT 15
3/26/16 - 24 wk post EOT - HCV NOT DETECTED!! AST 19, ALT 21
1 yr eot - AST 20, ALT 17

Offline drummerman

  • Member
  • Posts: 538
  • For those regarded as warriors....
Re: Vitamin D defeciency
« Reply #9 on: June 06, 2016, 09:22:20 pm »
Quote from: slats1056 on June 06, 2016, 08:50:09 am
Hey DM,

  Pluggin' for Ya big guy! Right there behind You. My re-check is in September. Strange how all of these anamolies keep popping up. But ,onward through the fog. Don't remember the WBC numbers on My latest Labs , but will check My file anyway.
  Not only was I Vit D deficient ( low end 30 & I was 17 ) , but had low Vit B levels as well. Need to check more into MINERAL levels also.

 Good luck and good to hear from You.
                                             Tommy

And good to hear from you!!!  My wbc was high the entire time I was on viekira.   Funny that I the time I did not even notice... too focused on the liver panels.
Logged
Diagnosed07
Interferon/riba 2008 - non-responder
5/16/15 - AST -34
ALT - 35_ HCV RNA - 10,783,000
 7/6/15 - started viekira/riba
8/11/15  Week 5 <15 vl,  AST 18, ALT 18
9/11/15 Week 9  "HCV NOT DETECTED"!
AST 16, ALT 11.  10/16/16 - 2 weeks post EOT = "HCV NOT DETECTED!   AST - 18,  ALT 14
12/29/15 -12 wk EOT-HCV NOT DETECTED! AST 23, ALT 15
3/26/16 - 24 wk post EOT - HCV NOT DETECTED!! AST 19, ALT 21
1 yr eot - AST 20, ALT 17

Offline Baxter

  • Member
  • Posts: 87
Re: Vitamin D defeciency
« Reply #10 on: June 09, 2016, 03:07:35 pm »
Quote from: drummerman on June 06, 2016, 09:16:09 pm
True that ... but they both do a good job...D2 is absorbed more easily and the D3 you have to take everyday.  I'm going to finish my D2 and then go D3, bottle is here and ready to go.   Course the best vitamin D source is the sun.... but it has been cloudy here for months.  Finally got a few days of sunshine.

dm

Even sunlight is not an adequate source of vitamin D for many people. The human body evolved to be outdoors all day long; most of us are lucky to catch even an hour of direct sunlight on an average day. And people who live in northern climates often have a  very hard time keeping the D levels up for much of the year. I take D3 all year round, no matter how much outdoor time I'm getting.
Logged
Gen 1a
Inf. '85
Dx '98
'98 biopsy - Grade 2, Stage 2, VL 7 mil
'01 biopsy - Grade 1, Stage 1, VL 1.5 mil
'08 biopsy - Grade 1, Stage 1, VL 3.5 mil
'12 biopsy - Grade 1, Stage 1, VL 3.5 mil
'16 Fibrosure - Grade I, Stage 3, VL 6.4 mil and 4.8 mil
4/23/16 - ALT 89, AST 50, pltlts 120k. Started 12 wks Harvoni
4/31/16 - ALT 30, AST 21, pltlts 125k
4/14/16 - ALT 25, AST 16, pltlts 126k, VL 69
5/11/16 - ALT 28, AST 21, pltlts 140k,VL <15
6/7/16 -EOT, UNDETECTED!
9/7/16 - cured. Low Stage 2 fibrosis
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