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Author Topic: Some help deciphering lab results  (Read 5272 times)

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Offline dtxhepb

  • Newbie
  • Posts: 2
Some help deciphering lab results
« on: October 12, 2016, 09:32:21 pm »
Background:  I was born with Hep B but didn't know it until I was 18.  At 34, my ALT/AST shot up to around 300, so my doctor put me on Baraclude .5mg daily to put a stop to that.  Since then, my ALT/AST has been around 10-15 with no detectable viral load.  I get bloodwork done every 6-12 months. 

My blood test from a year ago says the usual:

HBsAB, Qual - reactive
HBsAG - confirmed reactive
DNA viral load - undetectable
HBeAG - Positive
HBeAB - Negative

So now I'm 38 and I see something new appear on the bloodwork:

HBsAB, Quant - 10.60 mIU/ml
HBsAB, interpreted - Immune
HBsAG - confirmed reactive
DNA viral load - undetectable
HBeAG - Positive
HBeAB - Negative

With the appearance of the surface antibody, does that mean a start to seroconversion?  Or is this just false positive?



Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,534
  • Get tested, get treated, get cured, fight Hep c!
Re: Some help deciphering lab results
« Reply #1 on: October 12, 2016, 09:34:24 pm »
Hep B test results are difficult for a lay person to interpret you should ask your doctor.
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline dtxhepb

  • Newbie
  • Posts: 2
Re: Some help deciphering lab results
« Reply #2 on: October 12, 2016, 09:42:45 pm »
I plan to, but he is very hard to get ahold of.  It will be a week until I hear back from him.  I'm just curious if anyone else has seen these type of results.

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,534
  • Get tested, get treated, get cured, fight Hep c!
Re: Some help deciphering lab results
« Reply #3 on: October 12, 2016, 10:05:11 pm »
I haven't seen many hep b patients here who might know more about test results. I hope someone comes along to help you out.

I hope this might help

https://www.hepb.org/assets/Uploads/understanding-blood-tests.pdf

Understanding Hepatitis B Blood Tests

"Understanding your hepatitis B blood test results can be confusing. It is important to discuss your test results with your health care provider so that you can clearly understand whether you have a new infection, chronic infection, or have recovered from an infection. You may want to take this sheet with you to your appointment as a reference guide. In addition, it is helpful if you request a written copy of your blood tests so that you can be sure you know which tests are positive or negative."
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline lporterrn

  • Member
  • Posts: 1,969
  • LucindaPorterRN
    • LucindaPorterRN
Re: Some help deciphering lab results
« Reply #4 on: October 13, 2016, 04:38:16 pm »
Your doc will have to help you sort that one out. These results don't line up easily for me to even try to guess at. Here are more resources: https://www.cdc.gov/hepatitis/hbv/pdfs/serologicchartv8.pdf
https://www.hepmag.com/basics/hepatitis-b-basics/hepatitis-b-progression
https://www.hepmag.com/basics/hepatitis-b-basics/hepatitis-b-testing
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

 


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