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Author Topic: Harvoni Post Treatment – Possible Relapse  (Read 6201 times)

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Offline GSDAdventure0709

  • Newbie
  • Posts: 2
Harvoni Post Treatment – Possible Relapse
« on: April 07, 2017, 08:12:15 pm »
Hello —

New to the forum.

HCV G1 — no cirrhosis

I just got done 8 weeks of treatment on Harvoni. Started with VL of 600,000 and tested at week 4 with 0. Then at week 8 (treatment end) I tested with 90.

Dr. says that I need to test again in 4 weeks because I may actually be at 0, but the drug is still doing it's thing.

Has anyone ever experienced something like this?

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,545
  • Get tested, get treated, get cured, fight Hep c!
Re: Harvoni Post Treatment – Possible Relapse
« Reply #1 on: April 07, 2017, 08:30:17 pm »
We had at least one person here who was weakly detected at EOT and even 4 weeks post EOT but at 12 weeks post to not detected and remains so probably now about 2 years. Hopefully dragonslayer will see your post and chime in.

Even if you do end up with a relapse there have been several here who retreated with Epclusa and were subsequently cured.

Don't give up.
« Last Edit: April 07, 2017, 09:09:38 pm by Lynn K »
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!

Offline GSDAdventure0709

  • Newbie
  • Posts: 2
Re: Harvoni Post Treatment – Possible Relapse
« Reply #2 on: April 07, 2017, 08:52:35 pm »
Hi Lynn — That's incredibly encouraging, thanks for replying. Hopefully dragonslayer will see this and have some insight.

I'll have to look into Epclusa

It's hard going through treatment and then just waiting... and waiting... and waiting... to see if you're cured

Offline dragonslayer

  • Member
  • Posts: 873
Re: Harvoni Post Treatment – Possible Relapse
« Reply #3 on: April 07, 2017, 10:03:30 pm »
You rang?   Yes, as Lynn said, I was not only weakly detected at EOT, but at 8 wks post also.  Not til 12 wks post did I test Undetected and have remained SVR to this day, 2 yrs henceforth.. Cured!  Check my signature for details.  The hardest part is hanging tough til you get to the 12 wks post marker and having faith youll hit SVR12 at that point.    Please keep us up to date so we know whats going on...

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
likely infected early '70s


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