Welcome, Guest. Please login or register.
July 12, 2024, 11:01:36 pm

Login with username, password and session length


Members
Stats
  • Total Posts: 55130
  • Total Topics: 4851
  • Online Today: 257
  • Online Ever: 1314
  • (June 22, 2016, 05:23:42 am)
Users Online
Users: 0
Guests: 30
Total: 30

Welcome

Welcome to the Hep Forums, a round-the-clock discussion area for people who have Fatty Liver Disease, Hepatitis B, C or a co-infection, their friends and family and others with questions about hepatitis and liver health. Check in frequently to read what others have to say, post your comments, and hopefully learn more about how you can reach your own health goals.

Privacy Warning: Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.
  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.
  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.
  • Product advertisement (including links); banners; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from the Hep Forum Moderators.
Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: SVR 12! at last  (Read 7245 times)

0 Members and 1 Guest are viewing this topic.

Offline northfork

  • Member
  • Posts: 57
SVR 12! at last
« on: January 09, 2017, 12:38:17 pm »
Have got to share that I finally reached SVR 12!! This was my 3rd DAA treatment and the drug combo i took was the same as H.H. Burme's. Grateful that I could receive these drugs, as I was losing hope that I would ever be cured. I was undetectable from week 1. :)
Probably infected 1969. Diagnosed 2006. Genotype 1b.
Daclatasvir/ Asunaprevir 2013:relapse
Harvoni 24 weeks 2015:relapse
sofosbuvir, velpatisvir, voxillaprevir  trial started on drug 7/16. Viral load 890,000 approx. F2. Undetected after week 1.
12 week SVR achieved Jan 2017.
SVR 24 achieved April 2017 !

60 weeks post treatment...UNDETECTED!

Offline FutureThinker

  • Member
  • Posts: 711
  • Onward and upward!
Re: SVR 12! at last
« Reply #1 on: January 09, 2017, 01:37:02 pm »
HAPPY NEW YEAR, NORTHFORK!!!!  What a fantastic way to start 2017.  I guess there's something to that saying "3rd time's the charm"?  So very happy to hear you are now free of the beast.  All the best, FT
Treatment naive
Likely contracted mid-70s
Diagnosed 1a, 2011
F1-2
Harvoni X 12 weeks, completed 5/17/16
Pre-treatment: VL 3 mil, AST 64, ALT 84
4 week labs: VL 30, AST 21, ALT 14
8 week labs: VL UD!!!, AST 22, ALT 16
12 week labs: VL UD, AST 23, ALT 14
2 wk EOT: VL UD
12 wk EOT: VL UD, AST 22, ALT 13 =  SVR 12! Yay! 
Last hep appointment: VL UD, AST 19, ALT 12 = SVR 39! I AM DONE!

Offline northfork

  • Member
  • Posts: 57
Re: SVR 12! at last
« Reply #2 on: January 09, 2017, 02:32:50 pm »
Thank you. I guess I should be the poster child for DAAs. 60 weeks all told combining 3 different treatments, not counting the  36 weeks of placebos. Hey but who's counting? Just happy!
Probably infected 1969. Diagnosed 2006. Genotype 1b.
Daclatasvir/ Asunaprevir 2013:relapse
Harvoni 24 weeks 2015:relapse
sofosbuvir, velpatisvir, voxillaprevir  trial started on drug 7/16. Viral load 890,000 approx. F2. Undetected after week 1.
12 week SVR achieved Jan 2017.
SVR 24 achieved April 2017 !

60 weeks post treatment...UNDETECTED!

Offline northfork

  • Member
  • Posts: 57
Re: SVR 12! at last
« Reply #3 on: January 09, 2017, 03:03:52 pm »
Replying to my own post: my hat is off to the folks on this forum who endured many courses of interferon/ribavarin only to suffer relapse. That is hard time, and I can't complain about having to swallow a bunch of pills with little or no side effects. Just want to make that clear. :)
Probably infected 1969. Diagnosed 2006. Genotype 1b.
Daclatasvir/ Asunaprevir 2013:relapse
Harvoni 24 weeks 2015:relapse
sofosbuvir, velpatisvir, voxillaprevir  trial started on drug 7/16. Viral load 890,000 approx. F2. Undetected after week 1.
12 week SVR achieved Jan 2017.
SVR 24 achieved April 2017 !

60 weeks post treatment...UNDETECTED!

Offline elias

  • Member
  • Posts: 285
Re: SVR 12! at last
« Reply #4 on: January 10, 2017, 09:52:13 pm »
Congratulations, Norhfork

And thank you for participating in that trial which will no doubt help many others in the future.

I'm curious if at some point in your long ordeal with DAA's they did resistance testing? Or come up with some hypothesis as to why you had those failures?
Contracted HCV ~age 12
Diagnosed: September 2016 GT2b
F3 by Fibrosure: 0.66
Necroinflammat activity: A3 0.76
================
VL Sep. 12, 2016: 1.44 million/ Log: 6.157
AST:71/ ALT:114   Sept. 1, 2016 Before treatment
==================
4 week after beginning  Epclusa:
Viral Load: UNDETECTED
AST 17/ALT 11
===============
Began Epclusa:  October 22, 2016
End of Treatment [EOT]: January 13. 2017
====================
EOT+4 Weeks: UNDETECTED
====================
SVR 12 April14-HCV Not Detected

Offline northfork

  • Member
  • Posts: 57
Re: SVR 12! at last
« Reply #5 on: January 10, 2017, 10:30:16 pm »
Did not have resistance testing. My first clinical trial was in 2013. I think that was early in DAA therapy. I was prescribed 24 weeks of Harvoni due to my previous failure. They figured I was NS5A resistant, but thought the combo would work. It did not. Looks like this one did. In my opinion the book about HCV is far from being complete and we can expect many edits in the coming years. I plan to stay tuned.
Probably infected 1969. Diagnosed 2006. Genotype 1b.
Daclatasvir/ Asunaprevir 2013:relapse
Harvoni 24 weeks 2015:relapse
sofosbuvir, velpatisvir, voxillaprevir  trial started on drug 7/16. Viral load 890,000 approx. F2. Undetected after week 1.
12 week SVR achieved Jan 2017.
SVR 24 achieved April 2017 !

60 weeks post treatment...UNDETECTED!

 


© 2024 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.