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Author Topic: Week 7 post Harvoni. Need Support  (Read 7611 times)

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Offline steven_myers

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  • Posts: 33
Week 7 post Harvoni. Need Support
« on: February 27, 2017, 10:11:54 pm »
Hey, I hope everyone is doing well. I finished up Harvoni 7 weeks ago and showed undetected at 6 weeks and at EOT. I'm now waiting until 12 weeks for the big labs. Anyway, my mind has just been going with the unknowns and I could use some encouragement. Thanks :)

Offline Lynn K

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  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: Week 7 post Harvoni. Need Support
« Reply #1 on: February 28, 2017, 12:36:17 am »
Well if it helps at all being not detected at 4 weeks post your odds of staying that way is about 98.5% likely you will stay that way at SVR12 you were tested even later than that at 6 weeks.

I really believe it is very unlikely you will relapse at this point the odds are very much in your favor you are cured.

I know it was tough on all of us that long wait for SVR 12 but these meds are very effective so think positive you will be not detected and cured believe it!
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!

Offline steven_myers

  • Member
  • Posts: 33
Re: Week 7 post Harvoni. Need Support
« Reply #2 on: February 28, 2017, 07:32:29 am »
Thanks Lynn! I'm looking forward to letting you guys know the results of my 12 week SVR labs. Just 35 more days!

Offline FutureThinker

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  • Posts: 711
  • Onward and upward!
Re: Week 7 post Harvoni. Need Support
« Reply #3 on: February 28, 2017, 03:05:40 pm »
Hi Steven, and yes, we all know how difficult waiting for the "big test" is/was!! All you can do is try to relax, keep a positive attitude, occupy yourself w/ activities you enjoy, and wait.  It will be here before you know it, that day when you go in and get that very important test.  You can do this!

Lynn K has a great saying that got me thru a lot of times like these:

"Don't borrow worry and disappointment from a tomorrow that may never come"

Remember, the future is bright -- FT
Treatment naive
Likely contracted mid-70s
Diagnosed 1a, 2011
Harvoni X 12 weeks, completed 5/17/16
Pre-treatment: VL 3 mil, AST 64, ALT 84
4 week labs: VL 30, AST 21, ALT 14
8 week labs: VL UD!!!, AST 22, ALT 16
12 week labs: VL UD, AST 23, ALT 14
2 wk EOT: VL UD
12 wk EOT: VL UD, AST 22, ALT 13 =  SVR 12! Yay! 
Last hep appointment: VL UD, AST 19, ALT 12 = SVR 39! I AM DONE!

Offline Mugwump

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  • My number of posts means nothing, piscor ergo sum!
Re: Week 7 post Harvoni. Need Support
« Reply #4 on: March 02, 2017, 02:12:31 pm »
Steven your chances of not clearing are related somewhat to NS5A RAVs. If you were pretested for the known ones then you have even less to sweat about. HOWEVER even if you are NS5A RAV positive your chances of clearing are still very high. This is because the drug does still inhibit production of HCV even in those who have a NS5A RAV strain of HCV.

Secondly it seems that less than 10% of those who are GT1a have NS5A RAV strains of the virus.

Yes in some ways the wait to 12 weeks is a crap shoot and those who do fail to reach SVR deserve to feel cheated or cursed and mope and even throw bricks through windows!
But thank Heavens the crap shoot is not what it once was for us when most of us had less than a 50% chance of clearing and the treatment was 48 weeks in duration with interferon because we had GT1a. The riba rage and anemia damn near killed me the first time around and I can tell you that I felt like throwing some bricks through windows when I got the news that my year of treatment had failed in 2005.

Here is to you and a full cure very shortly! Even if you are amongst the unlucky few who fail treatment the current crop of new meds seem to eliminate the problem we had of becoming warehoused a few years back when we failed treatment. 8)

Also I suspect that Gilead is most likely being pushed to cut deals on treatment failures so just perhaps the insurance companies might not be as bad getting to a retreat. And there is some serious competition happening to the magic bullet Sovaldi.

Either way your odds of clearing are still in the high 90%s because you were clear at EOT so I would not sweat it.

Caution shameless self promotion below :-)

Offline steven_myers

  • Member
  • Posts: 33
Re: Week 7 post Harvoni. Need Support
« Reply #5 on: March 02, 2017, 03:49:35 pm »
Thanks everyone! I will keep you all posted shortly.

Offline Philadelphia

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  • It only looks like I know what I'm doing
Re: Week 7 post Harvoni. Need Support
« Reply #6 on: March 03, 2017, 08:21:42 am »
Looking forward to your good news. It's a long wait, we sympathise!
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013


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