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Author Topic: 2 Weeks in with Epclusa  (Read 9018 times)

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Offline singinasong

  • Member
  • Posts: 13
2 Weeks in with Epclusa
« on: October 14, 2017, 02:17:55 am »
Hi everyone.

I've just hit the two week mark and my experience so far is pretty unremarkable. I have had mild joint pains that are more like phantom pains that only last for a few minutes or so. They are not often.

I am used to having fatigue, but must admit that I actually have more energy than I normally do.

My biggest complaint about HCV is the neurological issues that I have had for the past 11 years. I'm really hoping that treatment helps my symptoms, but I know that this will take time post treatment.

This is my third treatment. I'm genotype 1a. In 2003, I was on the Pegasys Combo with Riba. I only lasted 11 weeks due to having serious thyroid issues. At that time, I was diagnosed with Graves disease and Graves ophthalmology. The next treatment was in 2011/12. I did triple therapy with Victrelis; started at 2.2M VL and ended at 11 weeks 3K VL.

This time, I get to do the full 12 weeks of treatment without a PCR test until I am finished.  I will have blood work done every four weeks to monitor my blood cells and liver enzymes. I wish I could see my results at 4 weeks, but I will have to remain patient and wait the full 12 weeks, plus the length it takes to get the PCR results.

Looking forward to journey with you all.

Thanks.

Singin  :)

PS. I tried to figure out how to create a signature to list my hx, but I couldn't figure it out  ::)

Epclusa, Pre Fibroscan 8.9kPa [F2]
Pre Tx: AST/ALT 67/83 4wks 36/34, 8wks 26/28

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: 2 Weeks in with Epclusa
« Reply #1 on: October 14, 2017, 06:19:42 am »
singinasong, glad to hear you are getting the energy boost that Harvoni gave me -- it's probably the sofosbuvir that both medicines contain. I assume you will get to see the results of your four-week blood work, and the AST and ALT will be improved and cheer you on.

As to creating a signature, on the middle menu bar (Home Forum Help . . . ), pull down Profile and choose Forum Profile. There's a large box that lets you enter a signature of up to 500 characters.

Best wishes,

Gnatty
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline singinasong

  • Member
  • Posts: 13
Re: 2 Weeks in with Epclusa
« Reply #2 on: October 14, 2017, 12:43:49 pm »
Hi Gnatty,

Nice to meet you. Thanks for the tutorial; It was right under my nose.

You are right. I will see the AST and ALT drop and that will be enough to keep my patience at bay.

Singin  :)

 
Epclusa, Pre Fibroscan 8.9kPa [F2]
Pre Tx: AST/ALT 67/83 4wks 36/34, 8wks 26/28

Offline singinasong

  • Member
  • Posts: 13
Re: 2 Weeks in with Epclusa
« Reply #3 on: October 29, 2017, 02:03:21 am »
I got my 4 week results in for AST/ALT and they are 34/36. Not what I was hoping for, but perhaps these numbers are due to a mildly fatty liver (as per latest ultrasound).

The AST/ALT numbers below during my last tx didn't hit these numbers until 12 weeks in, so I am hopeful. I also take a number of inhaled steroids everyday, so maybe this high normal is my normal.

I do feel better and think better, but I don't look better  ;)

Will have to wait and see...
Epclusa, Pre Fibroscan 8.9kPa [F2]
Pre Tx: AST/ALT 67/83 4wks 36/34, 8wks 26/28

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: 2 Weeks in with Epclusa
« Reply #4 on: October 29, 2017, 09:48:46 am »
Singin, if anyone deserves "third time's the charm," it's you. Amazing that you've stayed at F2 through everything! A big hooray on the AST/ALT numbers -- basing them on your personal hx rather than what's normal for most people makes sense to me.

Gnatty
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline singinasong

  • Member
  • Posts: 13
Re: 2 Weeks in with Epclusa
« Reply #5 on: October 29, 2017, 09:41:40 pm »
Thanks Gnatty. third time is a charm! :D

Yes, it's pretty amazing that I have stayed at F2 over the past 16 years. The doctor thinks I may have slow progression due to genetics, but that doesn't stop the symptoms. Luckily, I am able to treat it!

Wishing us all success and hope!



Epclusa, Pre Fibroscan 8.9kPa [F2]
Pre Tx: AST/ALT 67/83 4wks 36/34, 8wks 26/28

 


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