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Author Topic: I will start Vosevi retreatment soon  (Read 880 times)

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Offline mcmaklin

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  • Posts: 49
I will start Vosevi retreatment soon
« on: August 18, 2018, 12:49:11 pm »
Hello it seems I will start Vosevi in the middle of September. Please - any recommendations, what time or a day to take it, and do you have someone here who has been treated or failed the Vosevi? I have genotype 1b please look at the bottom. I had already one DAA treatment and I have L31M RAVs.
What about side effects etc. I can add that I was taking Viekira Exviera with no side effects at all.
2ndTreatmnt  geno 1b- Vosevi 12 weeks - SOT Sept 12 2018 to EOT Dec 5 2018. Pre-treatment - VL 1.4 mil, ALT 45, AST __, ALP 69, GGT 90, bilir 16. 2 weeklabs:VL 49, ALT 26, AST __, GGT 53. Bili 21, 4 weeklabs:VL <15, GGT42 other normal, 5weeklabs:ALT 17,AST 27, Bili 11.8,  ALP 68, GGT 36 ... VL 12,   6weeklabs ALT 19, AST 26, Bili 16,20, GGT35, VL<12

1stTreatm Compl. Viekira+Exviera no Riba Nov2015. 1b,TT,F1, 1400000U Relapsed 4 weeks EOT

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,079
  • Get tested, get treated, get cured, fight Hep c!
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Lukey

  • Member
  • Posts: 315
  • Let Thy Food Be Thy Medicine
Re: I will start Vosevi retreatment soon
« Reply #2 on: August 23, 2018, 01:50:59 pm »
I'm finishing 12 wks on Vosevi Sept 26. I have milk, tolerable SFX. I seem to get tired about 3 PM a lot, then I need a nap. It tended to dry out my GI tract and slow up my elimination. Drink lots of water. If you get SFX, try more water. Take your pill "about" the same time every day. I like mine with my mid day meal, since I eat only OMAD (one meal a day). It can be give or take an hour or so.  I felt a little achy last night, not bad. It's not bad at all and see my results below. I have 5 weeks to go on it.
Male -  HCV since 1982 - Born 1951 ~ Geno 1a

Did 8 weeks of Harvoni in 2015. Got normal AST & ALT and undetected VL by week 5, then relapsed 4 weeks post.
-----------------------------------------------------------
July 5, 2018 : began 12 weeks of Vosevi with a VL of 540,000 and AST & ALT of 65 and 105.
2 weeks in : AST 19, ALT 20
5 weeks in : AST 18, ALT 12, VL "<15 detected"
10 weeks in : AST 19, ALT 14, VL "<15 not detected"
4 weeks post : "<15 not detected"

Offline lporterrn

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  • LucindaPorterRN
    • LucindaPorterRN
Re: I will start Vosevi retreatment soon
« Reply #3 on: August 23, 2018, 02:29:58 pm »
The prescribing instructions says take it with food, once a day. I suggest taking it with the meal you are most likely to remember to take the pill with. I prefer morning for once daily pills since I eat breakfast at home daily.

If you put "vosevi" into the forum search field, you can find other posts about peoples' experiences.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
http://blogs.hepmag.com/lucindakporter/

 


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