Welcome, Guest. Please login or register.
January 17, 2019, 10:41:10 pm

Login with username, password and session length


Members
Stats
  • Total Posts: 53423
  • Total Topics: 4444
  • Online Today: 69
  • Online Ever: 1314
  • (June 22, 2016, 05:23:42 am)
Users Online
Users: 2
Guests: 55
Total: 57

Welcome

Welcome to the Hep Forums, a round-the-clock discussion area for people who have Hepatitis B, C or a co-infection, their friends and family and others with questions about hepatitis and liver health. Check in frequently to read what others have to say, post your comments, and hopefully learn more about how you can reach your own health goals.

Privacy Warning: Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.
  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.
  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.
  • Product advertisement (including links); banners; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from the Hep Forum Moderators.
Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: Are there any new studies out or statistics for Harvoni posttx 2018?  (Read 1545 times)

0 Members and 1 Guest are viewing this topic.

Offline robertk1997

  • Member
  • Posts: 6
Hi, I'm a 21 year old male who had gotten Hepatitis C for a very short period back in 2016 and we treated immediately with Harvoni (taken for 2 months I think?). It has been a very long time and I've nearly forgotten about the fact that I've had it. I only remember at random times when I think hard to myself about why it is I can't focus super well, or why my mind is sometimes foggy... I remember that I was on Harvoni and had hepatitis C at a point.

I become really depressed when I remember this because I try to push it out of my mind, and NEVER do I want to think of the possibility of the virus coming back. Truly a nightmare... especially being clean and finding some meaning in life - my past constantly haunts me in some way.

So the big question, are there any new studies or input from members in regards to Hep C post-tx (Harvoni specifically or just similar treatment) as to whether there are long term consequences, re-occurrence of the virus, or anything new that has emerged? I know I don't trust the FDA or pharmaceuticals at all anymore considering the modern model is based around the Rockefellers model from the early 1900's. Can anyone please give me any input - the good, great, bad, and ugly. Thank you,
Robert.

Offline andrew j

  • Member
  • Posts: 445
Re: Are there any new studies out or statistics for Harvoni posttx 2018?
« Reply #1 on: September 22, 2018, 07:49:32 pm »
Hi Robert,

My recovery has been reasonably normal, I think.
I am older than you are (61), and I had Hep C for about 40 years.
I am 2 years-or-so post-Tx.

Most people seem to recover normally - though I have to say - it seems that people who experience side-effects post-Tx have generally not experienced any symptoms prior to Tx - and vice versa.

I was really unwell when I had Hep C.
Getting treated has therefore been like some sort of miracle for me.
If there is a downside (there isn't, really) it's that I still seem to feel tired a lot - and easily run out of gas.
Otherwise - it's all good, as they say!

Some have reported mild adverse reactions to Tx, which require actively engaging in one's health post-Tx (including diet and exercise etc., and sometimes follow-up healthcare), and a few have, unfortunately, wound up with more serious side-effects, including general debilitation, severe joint and muscle pain, and skin conditions.

Once again, though, most people seem to be doing fine - which is a good thing considering the huge transformation that takes place treating something as insidious as Hep C.

Have a trawl around here, and look esp. at some of the stories on the homepage, and in the blogs section.

Hoping that you are doing OK today,

A.

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,079
  • Get tested, get treated, get cured, fight Hep c!
Re: Are there any new studies out or statistics for Harvoni posttx 2018?
« Reply #2 on: September 23, 2018, 12:57:07 am »
I had hep c for 37 years was diagnosed with cirrhosis after being infected for 30 years.

I treated three times in the past with interferon based treatments for six months each time but had no response to treatment. I treated with Solvadi and Olysio when they were first approved for 12 weeks but relapsed.

My fifth and last treatment was 24 weeks of Harvoni along with ribavirin because of my prior treatment history and cirrhosis.

I finished that treatment in May 2015 and remain cured. I feel great at 60 years old and living with liver cirrhosis for over 10 years now. I thank modern medicine every day for saving my life.

Best of luck to you and congrats on your cure.
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Mila

  • Member
  • Posts: 35
Re: Are there any new studies out or statistics for Harvoni posttx 2018?
« Reply #3 on: September 26, 2018, 06:41:00 pm »
You should check out this section of the forums:
Hepatitis C Research News & Studies

It's in the left side navigation.

I unknowingly had HepC for probably 40 or so years until I was properly diagnosed in 2015. I never had any symptoms and my AST level was literally 2 points above the high end of normal and they stayed there for decades while everything else was normal. When I found out I had it for sure and might never get sick from it, but was fully able to pass it on to others I decided to get treatment because I had a chance of developing symptoms and who wants to have that in their body? Or infect others...even worse!

I had a lot of side effects while on Harvoni and some that lasted for a time after but it was immediate that I noticed both the HepC and the Harvoni no longer in my body. So even the things I thought were normal were the result of HepC. Some were symptoms.

Bottom line is I finished my tx 2 years ago and I am not sorry about doing it. I am many years older than you are and already had reactions to other kinds of medications for other things, unrelated to HepC or Harvoni, so side effects from drugs was not lost on me. Ultimately, I ended up with Celiacs disease 4 days into tx and that did not go away. Frankly...if that is the worst it has to offer than I am grateful for it too. I'd rather not have a disease that would have made me so very ill and ravage my organs.

I don't eat gluten now and I am fine. Don't worry about this. Spend your new health and life living and not worrying about after effects of Harvoni. You are HepC free and that is huge. Its everything. This is your 2nd chance a gift that was unheard of 15 years ago.

Be well,
~Mila
Infected probably 1977/78
1st diagnosed: 2009
UN-diagnosed: 2012
RE-diagnosed by new Dr 2015
naive treament
genome type: 1a
Viral count at start of Harvoni treatment: 8,090,000
AST/SG: 51
ALT: 71
F1-2

4 Week:
HCV RNA: NOT DETECTED
AST/SG: 31
ALT: 44

8 Week:
HCV RNA: NOT DETECTED
AST: 33
ALT: 45

Week 12:
No HepC detected repeat in 3 months

2 years:
non detected

Offline mario555

  • Member
  • Posts: 225
Re: Are there any new studies out or statistics for Harvoni posttx 2018?
« Reply #4 on: November 21, 2018, 04:56:12 pm »
I had hep c for 43 years (my guess) and was borderline starting cirrhosis. I had failed 2 previous interferon treatments and had nothing to lose. I received 24 weeks of Harvoni and I felt I was overdosing towards the last 4-5 weeks! I finished my treatment almost 4 years ago. During the treatment I suffered from tinnitus and dizziness and I still have a fair amount of the two side effects. Tinnitus if I am tired or stressed and dizziness if I tilt my head to the left!
On the positive side I feel 10 years younger, I can digest anything I want and most wonderful, I can fall asleep in 5 minutes compared to 3 hours before!
I am very thankful to science and gilead and I would do the treatment all over again without hesitation (but for 20 weeks only......)
60 years old. Likely infected 1975. Geno 1a
F4  8 millions VL,  AST 140  ALT 140
Generally in good health except problems are creeping up rapidly!
2 failed attempts Inf 2000 and Inf-riba 2010
Harvoni 24 weeks
Start 11/13/2014   EOT 4/27/2015
VL2 - UND
VL4 - UND (may 25)
VL12 - UND
VK24 -  UND
Hopefully cured forever!

Offline slats1056

  • Member
  • Posts: 740
  • SVR to all and to all a good life!
Re: Are there any new studies out or statistics for Harvoni posttx 2018?
« Reply #5 on: November 21, 2018, 11:31:51 pm »
 Hi Robert,
   Check out this link . A lot of info. provided , so it will take some reading and patience! Found it last week and I am still breaking it down to My situation. You need to check out the references to Harvoni as well as by the drug names. ( Ledipasvir and Sofosbuvir ) A lot to take in , so take Your time and don't get discouraged.

  It will help out if You supply so of Your background info. as well.  I.E. Your genotype , viral load , liver enzymes , and such. Also , do You have any time frames from when You finished treatment and Your follow up tests for SVR12 or SVR24? I had some issues while on Harvoni Tx. as well as post Tx. most of which have gotten better slowly. With the exception of tinnitus and lingering joint pain to this day.

  I am currently on re-treatment with Mavyret for sixteen weeks ( just started week four Monday ) which is a breeze if I do say so Myself. Just turned 64 on the day You posted this , and have had HCV since 1973 . So that makes Me an old fart compared to You I guess ;D ;D ;D
  Anyway here is the link! http://www.natap.org/hcv.htm


                                                 Slats

 I AM JUST GOING TO PUT AN " OUT OF ORDER " STICKER ON MY FOREHEAD AND CALL IT A DAY!
73 non ab 98 hep c refused pegint/riba
6-15 Gen.1b 1/2 MIL ALT72 AST37 No cirrhosis
7-15  Harvoni 12 weeks
10-14-15 EOT VIRAL LOAD NON-DET  
12-30-15 EOT+12 VIRAL LOAD NON DET  SVR12            8-9-18 HCV LOAD 1.02IU/ml AST22  ALT30 RELAPSE?
9-18-18 confirmed gt 1b relapse
10-16-18 approved 16 weeks Mavyret

 


© 2019 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.