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Author Topic: Ladies, a question about Mavyret and taking birth control at the same time.  (Read 9892 times)

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Offline whitelotus51

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  • Posts: 7
Does anyone take Mavyret and the birth control pill? On the Mavyret website it says not to take a combination birth control pill while on Mavyret because of the estrogen. It says the estrogen can increase ALT liver enzyme levels. Any opinions on this? I called my specialty pharmacy as well and talked to a pharmacist. They advised against it, but then I talked to another pharmacist and they said it's fine, so I'm a bit confused. Is it better just to take a progestin only pill? I haven't started birth control yet but will be this week. Any opinions would be appreciated. Thanks!

Offline whitelotus51

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  • Posts: 7
Oh! And I will say I'm not looking for medical advice, but more so opinions on what other ladies are doing. Thanks :)

Offline Lynn K

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  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Personally I would suggest speaking with your doctor. What works for someone else may not be the best idea for you.
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline lporterrn

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  • Posts: 1,969
  • LucindaPorterRN
    • LucindaPorterRN
I agree with Lynn. I find the safety info lacking - maybe also a pharmacist. They clearly state it is recommended to not co-administer Mavyret with ethinyl estradiol-containing
medications, but the rest of the literature doesn't mention it, such as in the patient info. By co-administer, do they mean simultaneously or not at all?

Sorry I can't be more helpful, but I am stumped. Please let us know what you discover.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline whitelotus51

  • Member
  • Posts: 7
Thanks for the replies ladies. Yeah, it seems to be confusing. I had called my gastro doc today actually and they transferred me to the medical assistant. I asked all the same questions and she said "call the pharmacy who gave you the prescription". Which I have already done twice and talked to 2 separate pharmacists there like i previously mentioned. I'm actually going to my physician assistant tomorrow to talk about birth control. She works at a gynecology office, so yeah. I wonder if its a big deal anyway if the ALT level is elevated temporary for a few weeks anyway???

Offline Lynn K

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  • Member
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  • Get tested, get treated, get cured, fight Hep c!
My thought is even though it isn’t mentioned on every reference I found I would go with the recommendation unless there is a pressing need to use one of the not recommended types I would go with a preferred type of birth control better to err on the side of caution
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline lporterrn

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  • Posts: 1,969
  • LucindaPorterRN
    • LucindaPorterRN
Perhaps try the manufacturer's support line? The phone # is listed on their website:https://www.mavyret.com/
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

 


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