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Author Topic: FDA Warns of Rare Serious Liver Injury From Certain Hep C Meds  (Read 6861 times)

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Offline Hep Editors

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    • Hep Mag
FDA Warns of Rare Serious Liver Injury From Certain Hep C Meds
« on: September 30, 2019, 11:33:33 am »
The Food and Drug Administration (FDA) has issued a warning of rare liver injury, including liver failure and even death in some cases, that may occur among people taking the direct-acting antiviral (DAA) regimens Mavyret (glecaprevir/pibrentasvir), Zepatier (grazoprevir/elbasvir) and Vosevi (sofosbuvir/velpatasvir/voxilaprevir) to treat hepatitis C virus (HCV).

The advisory is based on 63 such reports, which largely involve individuals whose moderate to severe liver impairment meant that they should not have been prescribed these particular medications in the first place. Because Mavyret, Zepatier and Vosevi all contain drugs from the protease inhibitor class of DAAs, they are not indicated for use by people who have what is known as Child-Pugh B or C liver impairment.

Read more...
https://www.hepmag.com/article/fda-warns-rare-serious-liver-injury-certain-hep-c-meds

 


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