Fatty Liver Disease Main Forums > Nonalcoholic Steatohepatitis (NASH)

When Will We See Drug Treatments for NASH Fibrosis?

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Hep Editors:
Perhaps as many as one in four people in North America have non-alcoholic fatty liver disease (NAFLD), in which excess fat accumulates in the liver of an individual who drinks little or no alcohol. The disease is tightly linked with metabolic syndrome and insulin resistance and is a top driver of liver disease, including non-alcoholic steatohepatitis (NASH).

NAFLD and NASH often occur with fibrosis (scarring) of the liver, and yet to date no medications have been approved to treat such liver damage in this population. For anyone with NAFLD and fibrosis, the primary recommended treatment is moderate intensity exercise along with a healthy diet to promote weight loss.

Read more...
https://www.hepmag.com/article/will-see-drug-treatments-nash-fibrosis

FrancesLarsen:
Thanks for sharing! I didn't pay much attention to NAFLD until now.

FinleyMorse:
If I'm not wrong, NAFLD is the same as NASH, and both terms are related to obesity.

Lynn K:
NAFLD is non alcohol fatty liver disease and NASH is nonalcoholic steatohepatitis which is the later stage of liver injury

While NAFLD and NASH are associated with being overweight they can occur in patients who are not obese and can even occur in patients who are considered normal BMI

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959355/

FrancesLarsen:
The prevalence of NAFLD is alarming and the lack of approved treatments is concerning.

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